최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

국내 대형 EPC업체의 산업설비 상세설계 수행능력평가 및 문제점 분석

최종수,고윤혁 동국대학교 산업기술연구원 2007 산업기술논문집 Vol.16 No.2

본 연구의 목적은 국내 대형 EPC업체의 상세설계 역량을 평가하고 상세설계 프로세스상의 문제점을 도출하는데 있다. 연구결과에 의하면 국내 대형 EPC 업체들의 상세설계능력은 선진국 대비 상당 수준에 이르러 타 부문에 비해 경쟁력이 높은 분야로 평가되었으나 프로세스상에서 비효율적인 요소가 다수 있는 것으로 나타나 이를 해결함으로써 효율성을 높일 수 있는 여지가 있는 것으로 평가되었다. 파악된 비효율적인 요소들은 국제건설시장에서 국내 업체들이 경쟁력을 확보하기 위해 반드시 해결해야 하는 문제이며 짧은 시간에 적은 투자로 효과를 기대할 수 있는 분야로 사료된다. 본 연구를 통해 도출된 결과는 향후 산업설비 설계분야의 발전자 엔지니어링 핵심기술 확보에 기초가 되는 자료로 활용될 수 있을 것이다.

pefloxacin과 β-cyclodextrin 과의 포접화합물에 관한 연구

최윤수,김민숙 대구효성가톨릭대학교 1998 연구논문집 Vol.57 No.2

Inclusion complex of pefloxacin(PFX) with β-cyclodextrin(β-CyD) in aqueous solution and in solid phase was studied by solubility test, UV-and IR-spectrometry, melting point test and powder X-ray diffractometry. The stable solid inclusion complex of PFX-β-CyD was prepared by freeze-drying method and molar ratio of the inclusion complex(1:1) was obtained from elemental analytical data. The apparent stability constant k of the inclusion complex was calculated from the solubility diagram by Higuchi equation. Photodegradation studies of PFX and PFX-β-CyD inclusion complex were performed by photochemcial reactor with UV-B light source. Kinetic Photodegradation pattern of PFX and PFX-β-CyD inclusion complex were found as second-order reaction, but photodegradation rate of PFX-β-CyD inclusion complex was decreased than that of PFX alone.

상류지점 수위표 수위변동에 따른 하류지점 수위표 수위변동예측

최한규,임윤수,백효선 江原大學校 産業技術硏究所 2010 産業技術硏究 Vol.30 No.B

Generally, the accuracy of the prediction of flood elevation is difficult to identify due to the sedimentation on a river bed, earth and sand being moved by flow, and localized torrential downpours caused by climate change. It is also because of natural and artificial influences on rivers. To predict river floodings successfully, more precise and reliable flood elevation prediction system is needed, in which the concentration time of downstream is numerically interpreted through analyzing and utilizing the watermark of the upper region. Therefore, this research analyzed the prediction methods of the changes in water levels, which use the watermarks of the upper region. The watermarks which impacts the spot being predicted of flood was selected through floodgate analysis and correlation analysis. With the selected watermarks, a statistically reliable regression equation was yielded.

Butane gas가 흰쥐 혈청과 조직의 Lactatedehydrogenase 및 Cholinesterase에 미치는 영향

윤수홍,박은주,조수열,최현태 한국환경독성학회 1991 환경독성보건학회지 Vol.6 No.2

Acute poisoning with organic solvents and other volatile compounds now usually follows deliberate inhalation (volatile substance abuse) or ingestion of these compounds. The effect of butane gas inhalation was analyzed for serum, liver, brain, lung and muscle. And the observations are revealed on rat cholinesterase activity, lactatedehydrogenase activity and electrophoretic pattern of lactatedehydrogenase isozyme. The results are as follows: 1. The rat cholinesterase activity on serum, liver and muscle show the decreased by increasing of inhalation time of butane gas in particular the lung cholinesterase activity was greatly affected. 2. Butane gas inhalation brought out the lactatedehydrogenase activity increased of the serum and the tissues and had an important effect especially in both the liver and muscle lactatedehydrogenase activities. 3. Each tissue was found to have a characteristic distribution of lactatedehydrogenase isozymes on celluloseacetate electrophoresis and the development of inhalation time is shown the disappearance and diffusion of band. The toxicity of butane gas inhalation was most prominence in the liver and lung toxicity was occurred also.

충남대학교병원 마취발전의 경향에 관한 분석 : 1967년부터 - 1996년까지 from 1967 to 1996

최세진,김상수,정규돈,윤석화,신용섭,손수창,이원형,김혜자,이정은 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

To evaluate the specificity and historical trends of the anesthesia in Chungnam National University Hospital, anesthetic experiences of 83,572 in total performed at Chungnam National University Hospital from January 1967 to December 1996 were analyzed statistically and clinically according to age, sex, surgical department, physical status, elective and emergency surgery, premedicants, IV anesthetics, anesthetic methods, inhalational anesthetics, muscle relaxants. The results were as follows : 1. The number of cases has been steadily increased year by year. 2. The ratio of male to female was 52.8% : 47.2%. 3. According to the age, There were 44,905 cases (54%) in the group of 13-45 years. 4. According to the ASA classification of physical status, most of the cases were belonged to the class 1 & 2 (72.5%). 5. The ratio of elective to emergency was 79.4% to 20.6%. 6. Recently, glycopyrrolate has been used increasingly. 7. Thiopental sodium has been mainly used for intravenous induction agent. 8. General anesthesia has been used mainly. 9. Enflurane is the most common inhalational anesthetic agent. but Isoflurane has been used increasingly. 10. Most of muscle relaxants are Pancuronium & Vecuronium(84.5%).

Midazolam의 백서 기관평활근 이완효과와 Flumazenil의 길항작용

윤석화,신용섭,손수창,이원형,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Midazolam have been used widely as adjuvants in both regional and general anesthesia and in high risk patients in the intensive care unit. In the present study we evaluated the effect of midazolam and antagonistic effect of flumazenil on isolated rat tracheal preparations mounted for recording isometric contractile force. Trachea smooth muscle were contracted with acetylcholine (10^-5M, Ach) and potassium chloride (40mM KC1). Midazolam 5x10 exp (-6)M and 5x10 exp (-5)M produced dose-dependent relaxation and flumazenil (3.2 x 10 exp (-7)M), central antagonist of benzodiazepine, pretreatment had no significant change midazolaminduced relaxation. Midazolam probably did not relax airway smooth muscle by activatong central benzodiazepine receptors, as flumazenil did not block the concentration-related relaxation of midazolam. Our study suggests that flumazenil may be used satety for asthmatic patients who have been with midazolam, as flumazenil did not antagonize airway relaxation elicited by midazolam.

Pefloxacin의 광분해에 관한 연구 Ⅰ

최윤수,석경순,이경선 대구효성가톨릭대학교 응용과학연구소 1994 응용과학연구논문집 Vol.3 No.-

We investigated the photodegradation of pefloxacin(PFX) in some conditions. Pefloxacin was decomposed by light with different patterns in several solvents-ethanol, methanol and water. In the neutral and alkaline the rate of photo-degradation was more rapid than in acidic. When oxygen was replaced to N_2 gas, we found that it prevent pefloxacin from photodegrada-tion. Using the singlet oxygen scavenges-sodium azide and α-tocopherol, we obtained an indica-tive evidence of that photo-degradation pathway is mediated by singlet oxygen.

골반강 종괴로 재발한 악성 난소 갑상선종

최수임,윤혜경 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Malignant struma ovarii is a rarely reported disease and the diagnostic criteria is still in debate. A 43 years old woman admitted to our hospital because of palpable lower abdominal mass in 1993. On ultrasonography, a cystic mass, measuring 6.1cm in long diameter, was found in the left ovary, and laparoscopic left salpingo-oophorectomy was performed. Submitted left ovarian tissue consisted of multiple fragments, and focal yellowish brown nodules were seen along the inner side of the cystic mass. Microscopically, mature cystic teratoma with focal thyroid tissues exhibiting usual nodular hyperplasia of thyroid gland or follicular adenoma of fetal type and positive reaction for thyroglobulin was observed. Neither cytologic atypia of follicular cells nor mitosis were found in the thyroid tissue, but thyroid tissue showed focal infiltrative borders into ovarian stroma and evidence of vascular invasion. The thyroid function test was within normal limit, and no abnormal finding was noted on thyroid scan at that time. In 2002, TAH with right salpingo-oophorectomy was done because of hypermenorrhea and palpable lower abdominal mass. A cystic mass and multiple small yellowish brown nodular lesions were found along the serosal surface of the uterus. Microscopically findings suggesting papillary carcinoma of thyroid gland, follicular variant, were noted. In 2003, segmental resection of small intestine and rectum were performed, and nodular lesion involving the rectal wall showed features suggesting follicular carcinoma of thyroid gland. We report a case of malignant struma ovarii recurred in the pelvic cavity, 9 years after left oophorectomy.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.