Sezary증후군과 병발된 용혈성 빈혈 1예

유광하,진춘조,김홍승,이종인,심영학,정순희,이창훈 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

저자등은 전신적인 소양감을 동반한 홍반성 판상의 피부 병변과 자가 면역성 용혈성 빈혈이 동반된 Sezary 증후군을 진단하고 복합 화학 요법 CHOP으로 치료하여 피부 증상과 빈혈이 호전된 예를 문헌고찰과 함께 보고하였다. Sezary syndrome(SS), a leukemic variant of cutaneous T-cell lymphoma(CTCL), is monoclonal proliferation of CD4 T-cell having cerebriform nuclei in the skin and the peripheral blood. It is associated with erythroderma, pruritis, lymphadenopathy with protracted clinical course and systemic spread. We present a case of SS i a 38-year-old woman with generalized exfoliative erythroderma, plaques, and pruritus. Histopathologic findings of the skin lesions revealed infiltration of atypical lymphocytes in the dermis and epidermis. Electron microscopic findings of peripheral blood and skin showed atypical lymphocytes with cerebriform nuclei. Laboratory findings revealed direct Coombs' positive autoimmune hemolytic anemia, a rare association of SS. Chemotherapy with CHOP produced improvement of the skin manifestation and anemia.

사회적 지원이 섬유산업 종사자의 직무스트레스 징후 및 직무성과에 미치는 영향

유화숙,박광희 한국의류산업학회 2005 한국의류산업학회지 Vol.7 No.1

The pm-pose of this study was to investigate social support buffering stress symptoms and the relationship between stress symptoms and job performance. The data were obtained from questionnaires completed by 529 workers employed in textile or clothing companies. The SPSS package was used for data analysis which included t-test, ANOVA, and correlation analysis. The results showed there were significant differences in the perceived levels of social support according to individual differences such as gender, marital status, length of service, title of current position, and division of responsibility. Workers with a high level of supervisor or co-worker social support were found to have the lower levels of stress symptoms. Social support appeared to moderate the relationship between stress symptoms and job performance.

Sezary증후군과 병발된 용혈성 빈혈 1예

유광하,진춘조,김홍승,이종인,심영학,정순희,이창훈 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

대장게실염 -18 예-

김광연,차귀현,이영희,유경수 대한대장항문학회 1986 Annals of Coloproctolgy Vol.2 No.1

태권도 지도자들이 체육관 경영 시 고려하는 주요 요인 분석

조광민,이건희,김상유 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

Taekwondo which has adopted as a formula competitive games in 2004 Athens Olympic is establishing itself as world-widely recognized marshal arts, Taekwondo training centers which perform most of Taekwondo education, however, have been giving rise to many problems, Among others, reduction of the number of training peoples and limited an age group are the most serious ones. The purpose of this study was to help the Taekwondo trainers with solving various problems, such as facilities, trainer's quality, and training programs, and with consequently managing successful training center. It was abstracted by cluster random sampling method from Taekwondo Masters who work or operate Taekwondo Gym A questionnaire was sent to a Taekwondo Masters, Out of 300 copies, 196 copies were actually used in the practical analysis, Any copies with lost pages or insincere answers were excluded. For this study, SPSS 11.0 for Windows statistic package were used to analyzing collected samples, To analyze the data, frequency analysis, multiple responses, t-test, factor analysis, One-way ANOVA were conducted. And Scheffe method was used for the post analysis, investigating the propriety of the questionnaire, the factors analysis was executes by varimax after the professionals' review about the selecting Taekwondo Gym. As the result of the factor analysis, Factor 1 was named as the master's talent, Factor 2. as the accessive to the Taekwondo Gym and Factor 3 as the facility of Taekwondo Gym, And internal, external of Master, In the questionnaire of this study, reliability was used to verifying All Cronbach's a were over .700. As a conclusion, a diet program or a physical-training program need be developed forvarious groups of customers from the youth to the old, and training programs and in future study, marketing strategy for regional. needs should also be made.

광용혈에 의한 Phenothiazine류의 광독성에 관한 연구

白光欽,金鳳姬,柳柄泰 충남대학교 약학대학 의약품개발연구소 1987 藥學論文集 Vol.3 No.-

To investigate the phototoxicity of phenothiazines, five phenothiazines and one thioxanthene derivative were examined by using a 40W BLB fluorescent tube in the buffered (phosphate buffered saline and veronal buffered saline) reaction system consisting of human RBC (20 V/V%) and the drugs in concentrations from 1㎍/㎖ to 100㎍/㎖. The extent of photohemolysis was examined by a spectrophotometer. It was also observed that toxic photoproducts were formed by perphenazine and chlorpromazine. All of the active compounds showed more potent photohemolyzing activities in veronal buffered saline than in phosphate buffered saline. Substitution in 2-position of phenothiazine structure is thought to enhance this capacity, and particularly so when the substituent is chlorine. Substitution in 10-position of phenothiazine structure may also augment the phototoxic activity, though to a lesser degree.

하악 고정성 임프란트를 이용한 퇴축된 하악골의 수복

정영진,박원희,안원준,이명렬,이영수,유광희,심광섭 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.2

Transmandibular implants are used limitedly such as on remaining symphyseal basal bone of atrophic mandible, on the bony defect of symphyseal area due to trauma or tumor as surgical implants. Among the more recent advances in oral implantology are the Fixed Mandibular Implant (FMI)based on the pioneering studies and clinical applications by Irwin Small of the USA and the development very high success rates for providing attachments and abutments in areas of the oral cavity severely compromised by either atrophy or surgical loss of osseous tissues. We will present a case report of regabilitation of totally edentulous mandible with advanced alveolar atrophy using Fixed Mandibular implant (F.M.I).

3개 대학병원의 주 진단 코딩사례 평가

서순원,김광환,부유경,서진숙,서정돈,윤석준,이영성,이무식,정희웅 한국의료QA학회 2002 한국의료질향상학회지 Vol.9 No.1

Background : Coding of principal diagnosis is essential component for producing reliable health statistics. We performed this study to evaluate the current practice of principal diagnoses determination and coding, and to give some basic data to improve coding of principal diagnosis. Method : Nineteen medical record administrators(MRAs) of 3 university hospitals participated in coding principal Dx. From August 1, 2001 to August 31, 2001. From each hospital, 10 medical records of patients with high frequency disease were selected randomly. Each 10 medical records were grouped into three(A,B,C). Then, these 30 medical records were given to each MRAs for coding. At the same time questionnaire was given to each of them. Questions were to prove how they decide and code the principal diagnosis among many current diagnoses ; how they decide and code the principal diagnosis when day see irrelevant diagnosis recorded as the principal diagnosis in medical record, when only tentative diagnoses were recorded without final diagnosis, and when different diagnoses were recorded in different sheets of same record. Agreement of coding among 3 hospitals were compared and survey results were analysed with SAS 6.12. Results : Agreement of coding was found in medical records 5-6 of each 10 medical records. Causes of disagreement were as follows. Difference of clinician’s opinion from each hospital; mixed use of guideline from KCD-3 and guideline from DRG; difference in 4th digit classification according to the absence of pathology report in the medical record; difference of abbreviations among hospitals. 57.9% of decided principal diagnosis after consulting to KCD-3 guideline. When there were difficulties in determining the principal diagnosis, 42.1% of MRAs decided principal diagnosis after discussion with the physician, 26.3% after discussion with fellow MRAs. Conclusion : There were differences in coding among hospitals. To minimize the difference, we suggest the development of disease-specific guidelines for coding in addition to the current general guideline such as KCD-3. To do this, Coding Clinic which can produce guidelines is needed.

녹차 및 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용

임성훈,서정순,윤영주,김광원,유소영,김화숙,국중기,이병래,차종희,박재윤 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.5

본 연구는 치아우식증에 관련된 Mutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연 생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 50% 에탄올을 이용하여 얻었다. 이들 추출물의 Mutans streptococci 표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장억제농도는 5 mg/ml이었다. 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다. Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatment. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casio tora were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5 mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea may be more effective than the tea prepared from C. tora in the prevention of enamel decalcification or dental caries around brackets.

정밀어태치먼트의 완압정도에 따른 하악국소의치의 지지조직에 대한 3차원 유한요소 응력분석

정연진,우순섭,이영수,심광섭,유광희 한양대학교 의과대학 1999 한양의대 학술지 Vol.19 No.1

The purpose of this study was to evaluate the stress distribution developed in the supporting structures by mandibular distal extension removable partial dentures with 4 different precision attachments. The examined precision attachments were Mini SG attachment, CM box attachment. Mini Dalbo attachment, Technoroach attachment. Concentrated force(vertical force 200N, horizontal force 50N) was applied on the artificial 2nd molar of the removable partial dentures and distributed force(vertical force 100N, horizontal force 25N) was applied on the each artificial 1st, 2nd molars of removable partial dentures. Total 4 cases were compared and analyzed with 3-dimensional finite element method. And then, stress distribution patterns were analyzed and compared. The results were as follows. 1. In case of concentrated force; Maximal stress distribution was showed on the alveolus under artificial 2nd molar and then, stress mainly distributed on the residual alveolus of the denture base. 2. In case of distributed force; Maximal stress distribution was showed on the distal alveolar crest of distal abutment, and then, stress mainly distributed on the alveolus of mesial and distal abutments. 3. The stress of residual alveolus of non rigid attachment was greater than that of rigid attachment. 4. The stress of abutments of rigid attachment was greater than that of non rigid attachment.