만성 발목 관절 외측 불안정성의 진단에서 스트레스 방사선검사의 유용성

김용민,조병기,김동수,최의성,손현철,박경진,김동환,Kim, Yong-Min,Cho, Byung-Ki,Kim, Dong-Soo,Choi, Eui-Sung,Shon, Hyun-Chul,Park, Kyoung-Jin,Kim, Dong-Hwan 대한정형외과스포츠의학회 2011 대한정형외과스포츠의학회지 Vol.10 No.1

목적: 만성 발목 관절 외측 불안정성 환자에 대한 기계적 불안정성의 평가에서 스트레스 방사선검사의 진단적 유용성을 알아보고자 하였다. 대상 및 방법: 본원에서 변형 Brostrom 술식을 시행받은 환자들 중 수술 소견상 외측 측부인대(전 거비 인대)의 완전 파열이 확인되었던 42예를 대상으로 하였다. 대조군으로는 발목 관절 손상의 과거력이 없고 이학적 검사상 불안정성 소견을 보이지 않는 정상 한국인 성인 총 60명(120예)을 모집하였다. Telos 기구를 이용한 전방 전위 및 내반 스트레스 검사를 시행한 뒤, 거골 경사각과 거골 전방전위 정도를 계측하였다. 대조군에서 얻어진 정상범위를 기준으로 스트레스 방사선검사의 민감도, 특이도, 양성 예측도, 음성 예측도를 분석하였다. 결과: 스트레스 방사선검사 상 정상 한국인 성인에서의 거골 경사각은 평균 $4.2{\pm}2.1$도, 거골 전방전위는 평균 $3.9{\pm}1.9$ mm로 계측되었다. 95% 신뢰한계 분석을 이용한 정상 범위의 설정시 거골 경사각의 정상 범위는 8.3도 이하, 거골 전방전위는 7.6 mm 이하로 분석되었다. 이 수치를 기준값으로 하는 경우 발목 관절 스트레스 방사선검사 상 거골 경사각의 민감도는 57%, 특이도는 97%, 양성 예측도는 89%, 음성 예측도는 86% 였고, 거골 전방전위의 민감도는 69%, 특이도는 97%, 양성 예측도는 91%, 음성 예측도는 90% 였다. 결론: 만성 발목 관절 외측 불안정성 환자에 대한 기계적 불안정성의 평가에서 스트레스 방사선검사는 비교적 우수한 특이도 및 양성, 음성 예측도를 보였으나 민감도는 낮아, 유용하지만 정확성은 떨어지는 검사법인 것으로 분석되었다. 기계적 불안정성이 발목 관절 스트레스 방사선검사 상 실제보다 덜 반영된다고 생각되며, 스트레스 방사선검사 소견만으로 발목 관절 외측 불안정성을 배제해서는 안 될 것으로 생각한다. Purpose: This study was performed to evaluate the diagnostic usefulness of ankle stress radiograph for evaluation of chronic lateral ankle instability. Materials and Methods: Among patients undergoing the modified-Brostrom procedure, 42 cases with complete rupture of the anterior talofibular ligament were enrolled in this study. Sixty Korean adults (120 cases) were recruited as the control group. Radiologic measurement of talar tilt and anterior talar translation was performed through stress radiographs using Telos device. We obtained the normal range of Korean adults, and used as a standard value for judgment of mechanical instability. We analyzed the sensitivity, specificity, positive and negative prediction value of ankle stress radiograph. Results: On ankle stress radiograph, normal range of talar tilt angle and anterior talar translation was below $8.3^{\circ}$, below 7.6mm. Talar tilt angle on varus stress radiograph showed 57% of sensitivity, 97% of specificity, 89% of positive and 86% of negative prediction value. Anterior talar translation on anterior drawer stress radiograph showed 69% of sensitivity, 97% of specificity, 91% of positive and 90% of negative prediction value. Conclusion: Ankle stress radiograph had a good specificity, positive and negative prediction value for the evaluation of mechanical instability. However it underestimated the mechanical instability of ankle joint. It must be remembered that normal stress radiograph does not exclude ankle instability.

순서기반 비정상행위 탐지 센서의 임계치 결정 방법

김용민,김민수,김홍근,노봉남,Kim, Yong-Min,Kim, Min-Su,Kim, Hong-Geun,No, Bong-Nam 한국정보처리학회 2001 정보처리학회논문지 C : 정보통신,정보보안 Vol.8 No.5

본 논문은 SOM과 HMM을 이용하여 시스템 호출 수준에서 순서기반의 비정상행위 탐지 센서를 구현하였다. 그리고, 시스템 호출에서 중요한 정보가 무엇이고 임계값은 어떻게 설정해야하는 지를 분석하였다. 본 논문에서 사용한 SOM의 새로운 필터링 규칙과 축약 규칙은 HMM의 입력 크기를 줄일 수 있었다. 이러한 축약은 HMM기반 비정상행위 탐지의 실시간 처리능력을 보장해 준다. 또한, 비정상행위 수라는 개념을 도입하여 HMM의 탐지결과에 대한 민감성을 둔화시켜서, 사용자가 탐지결과를 쉽게 이해하고 false-positive를 줄이는 효과가 있었다. 그리고, 능동적으로 threshold 값을 조정하여 시스템 상황에 따라 탐지센서가 적응할 수 있도록 하였다. In this paper, we implement sequence-based anomaly detection sensor using SOM and HMM, and analyze what is important information in system call and how a threshold is decided. The new filtering and reduction rules of SOM reduces the input size of HMM. This gives real-time processing to HMM-based anomaly detection sensor. Also, we introduced an anomaly count into the sensor. Due to lessened sensibility, a user easily understand easily the detection information and false-positive was decreased. And the active coordination of the threshold value makes the detection sensor adapt according to the system condition.

Anti-Inflammatory Effects of Tongbi-san(通痺散) Extract on RAW264.7 Macrophages

김용민,김희택,김이화,Kim, Yong-Min,Kim, Hee-Taek,Kim, Ee-Hwa The Society of Korean Medicine Ophthalmology 2016 한방안이비인후피부과학회지 Vol.29 No.4

Objectives : This study is to investigate the anti-inflammatory and anti-oxidant effects of Tongbi-san extract (TS) on RAW264.7 macrophages using by cell cytotoxicity, Nitric Oxide (NO) and Prostaglandin $E_2$ ($PGE_2$) production and 1,1-diphenyl-2-picryl ghdrazyl (DPPH) free radical scavenging capability. Methods : Cell cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The production of NO was measured by Griess assay. The production of $PGE_2$ was measured by immunoassay. And the anti-oxidant activity was measured by the DPPH method. Results : TS did not increased significantly compared to the TS untreated group in the cell cytotoxicity. TS inhibited NO and $PGE_2$ production in lipopolysaccharide-stimulated RAW 264.7 cells. TS had the DPPH free radical scavenging capability. Conclusion : The anti-inflammtory and anti-oxidant effects of TS may be use for a treatment of anti-inflammatory diseases.

백내장 수술 후 각막 지각의 변화와 각막신경 회복의 비교

김용민,김선웅,김태임,김응권,서경률,Yong Min Kim,Sun Woong Kim,Tae Im Kim,Eung Kwon Kim,Kyung Ryul Seo 대한안과학회 2007 대한안과학회지 Vol.48 No.1

Purpose: To compare corneal sensitivity and recovery of corneal innervations after a temporal clear corneal incision in cataract surgery. Methods: We measured changes to corneal sensitivity using Cochet-Bonnet esthesiometer in 25 eyes of 20 patients and analyzed corneal nerve density with confocal microscopy in 20 eyes of 20 patients who had undergone cataract surgery. The parameters were measured before, and at 1 week, 1 month, and 3 months after cataract surgery. Results: The mean preoperative corneal sensitivity was 56.40±3.39 mm at the temporal corneal incision site, and there was a significantly decreased sensitivity of 29.80±2.69 mm and 42.40±4.36 mm postoperatively at 1 week and 1 month, respectively. Nonetheless, by three months, corneal sensitivity had returned to 56.00±2.89 mm and was not significantly different from measurements prior to the cataract surgery. The mean preoperative subbasal nerve density was 5296±1642 ?m/mm2. After cataract surgery, the subbasal nerve density was significantly reduced to 4113±1421, 3555±1448, 4198±1239 ?m/mm2 at 1 week, 1 month, and 3 months, respectively. Conclusions: Corneal sensitivity after cataract surgery returned to near preoperative levels within 3 months before complete restoration of normal corneal innervations. Therefore, regeneration of subbasal nerve fibers (, as determined by confocal microscopy,) requires more time than the return of corneal sensation after cataract surgery.

당뇨황반부종의 치료에서 유리체 절제술의 효과와 유리체강 내 트리암시놀론 주입술과의 비교

김용민,김성수,이성철,권오웅,고형준,Yong Min Kim,Sung Soo Kim,Sung Chul Lee,Oh Woong Kwon,Hyung Jun Koh 대한안과학회 2006 대한안과학회지 Vol.47 No.7

Purpose: The purpose of this study is to evaluate the benefit of pars plana vitrectomy (PPV) and removal of the internal limiting membrane (ILM) in diabetic macular edema, and to compare the effects of PPV and removal of ILM with intravitreal triamcinolone acetonide injection. Methods: Fifteen eyes of 14 patients on whom PPV and removal of the ILM (group A) were performed and 14 eyes of 14 patients who received single intravitreal triamcinolone acetonide injection (group B) for diabetic macular edema over six months were included in this study. The main outcome measures were macular thickness, as measured by optical coherence tomography and visual acuity at 1, 3, and 6 months postoperatively. Results: The mean preoperative visual acuity was 0.06±0.05 and macular thickness 516.01±120.29 ?m in group A. At 1 month postoperatively, this group showed no significant improvement of visual acuity. However, there was significant improvement at 3 and 6 months postoperatively. Macular thickness also decreased significantly at 1, 3, and 6 months postoperatively. In group B, the mean preoperative visual acuity was 0.10±0.08 and macular thickness was 548.82±116.44 ?m. At 1 and 3 months postoperatively, significant improvement of visual acuity was noted in this group. However, there was no significant difference at 6 months postoperatively. Macular thickness also decreased significantly at 1, 3, and 6 month postoperatively. Between two groups, visual acuity and macular thickness improved in Group B at 1 month postoperatively but at 6 months, visual acuity improved in Group A and there was no significant difference of macular thickness between the two groups. Conclusions: PPV and removal of the ILM are good therapeutic options for diabetic macular edema to improve visual acuity and macular thickness. These also offer more long term efficacy than intravitreal tiamcinolone acetonide injection.

희토류 원소를 이온주입법으로 도핑한 GaN 박막의 광전이 특성

김용민,Kim, Yong-Min 한국진공학회 2007 Applied Science and Convergence Technology Vol.16 No.3

사파이어 기판위에 성장된 GaN 기판위에 희토류 원소인 Gd을 이온주입 (ion-implantation)법으로 도핑한 시료에 대하여 온도 변화에 따른 광발광 (photoluminescence) 특성을 연구하였다. 이온주입 도핑에 따른 광전이 특성은 전이 진폭이 저온 (5 K)에서 590 nm 근처에서 최고값을 갖는 불순물 전이가 나타남을 보인다. 이때 이 전이는 온도가 올라감에 따라 세기강도는 감소하나 청색편이 현상을 보이며 200 K 이상에서는 오히려 세기강도가 증가하는 비정상 전이 특성을 보임을 관측하였다. 이러한 비정상 광전이는 희토류 불순물 효과와 이온주입에 따른 결정격자의 불완전성에 기인하는 것으로 여겨진다. We have studied optical transitions of Gd-implanted GaN epilayers. Photoluminescence transition intensity at 590 nm at T=5 K diminishes and its center position moves to short avelength (blue shift) with increasing temperature up to 200 K. Above T=200 K, the transition intensity increases with increasing temperature while the center position remains the same. We believe that such anomalous optical transition behavior is due to the effect of rare-element in the semiconductor host material and lattice imperfection which was occurred during the implantation process well as.

JPEG 인코더를 위한 고성능 병렬 프로세서 하드웨어 설계 및 검증

김용민,김종면,Kim, Yong-Min,Kim, Jong-Myon 대한임베디드공학회 2011 대한임베디드공학회논문지 Vol.6 No.2

As the use of mobile multimedia devices is increasing in the recent year, the needs for high-performance multimedia processors are increasing. In this regard, we propose a SIMD (Single Instruction Multiple Data) based parallel processor that supports high-performance multimedia applications with low energy consumption. The proposed parallel processor consists of 16 processing elements(PEs) and operates on a 3-stage pipelining. Experimental results for the JPEG encoding algorithm indicate that the proposed parallel processor outperforms conventional parallel processors in terms of performance and energy efficiency. In addition, the proposed parallel processor architecture was developed and verified with verilog HDL and a FPGA prototype system.

구기자 복합물 약침액이 간기능 개선에 미치는 영향

김용민,황동석,곽병문,김이화,Kim, Yong-Min,Hwang, Dong-Suk,Kwak, Byeong-Mun,Kim, Ee-Hwa 경락경혈학회 2019 대한침구의학회지 Vol.36 No.4

Objectives : This study investigated the hepatoprotective effect of herbal mixture including Lycii fructus (HML) in thioacetamide (TAA)-induced hepatotoxicity in mice. Methods : To confirm the liver protective effect, induced by TAA for 3 days injection at 100 mg/kg mice, HML were treated for 8 weeks at 300 mg/kg/day, 1000 mg/kg/day. Positive control was treated silymarin 50 mg/kg/day after TAA injection. The changes of mortality rate, clinical signs, organ weight, relative liver, blood chemistry and histopathological findings were analyzed after experiment. Results : Body weight gain was observed in all groups, but TAA treated group at 4th week and all treated groups decreased weight compared to the untreated group. As a result of organ weight measurement, organ weight gain due to hepatic injury was observed statistically significantly in TAA-treated group and TAA+Silymarin treated group, and the herbal mixture-treated group showed a tendency to decrease compared to the TAA treated group. Blood biochemistry showed that total cholesterol and very low density lipoprotein cholesterol decreased statistically in TAA+low-dose and high dose herbal mixture treated group compared to the TAA-treated group. Histopathological examination showed that liver abnormalities were not observed in untreated group, liver fibrosis was observed in liver injury with TAA treated and herbal mixture treated group. And, TAA+high dose herbal mixture group showed relaxation tendency on liver calcification compared to the TAA treated group. Conclusions : According to the above results, HML provided hepatoprotective effects on the hepatic injury by reduction of inflammatory responses.

불포화 풍화토 사면의 모관흡수력 분포에 대한 지반조건과 강우강도의 영향

김용민,이광우,김정환,Kim, Yong Min,Lee, Kwang Woo,Kim, Jung Hwan 대한토목학회 2013 대한토목학회논문집 Vol.33 No.3

본 연구에서는 강우 침투에 의한 사면의 모관흡수력 분포특성을 분석하기 위하여 수리학적-역학적 특성을 고려한 동시연계해석을 수행하였다. 이를 위해, 국내 3가지 지역에서 채취한 풍화토를 대상으로 함수특성곡선(SWCC)을 산정하였으며, 이를 토대로 지반조건, 강우특성, 사면경사에 따른 모관흡수력의 변화를 관측하였다. 그 결과, 강우강도가 증가함에 따라 사면내의 모관흡수력은 급격히 감소하는 경향이 나타났으며, 사면 경사에는 큰 영향을 받지 않는 것으로 나타났다. 또한 강우강도보다 포화투수계수가 작은 지반은 표층에서 포화가 쉽게 일어나는 것을 확인하였으며, 다층으로 존재하는 경우에도 사면표층 지반의 수리학적 특성이 모관흡수력 분포에 큰 영향을 주는 것으로 나타났다. The monolithically coupled finite element analysis for a deformable unsaturated soil slope is performed to investigate matric suction distribution on a soil slope subjected to rainfall infiltration, which can consider the hydraulic-mechanical characteristics for the analysis. The soil-water characteristic curves (SWCC) are experimentally determined to estimate three types of hydraulic properties of domestic areas. Based on the physical properties, the distribution of matric suction is investigated by considering the major factors, such as soil conditions, rainfall intensities, and slope angles. It is found from the results of this study that the matric suction rapidly decreases with an increase in rainfall intensity, regardless a slope angle. The slope surface is more easily saturated when its saturated hydraulic conductivity is smaller than rainfall intensity, and for the case of multi-layered soil slope, hydraulic characteristics of slope surface has a significant influence on matric suction distribution.

가스저장탱크 제조업의 보건관리 사례

김용민,Kim, Yong-Min 대한산업보건협회 2007 산업보건 Vol.230 No.-