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      • KCI등재

        Realistic Visualization of Car Configurator Based On Unreal Engine 4(UE4)

        Yiming Zhong,윤태수,이병천 한국인터넷방송통신학회 2022 International Journal of Internet, Broadcasting an Vol.14 No.1

        The platform for displaying cars has been changing with the times. From the popularity of paper media to the rise of computer graphics, the improvement of technology has brought more space and possibilities to the automotive industry. Yiming Zhong proposed the workflow of car configurator through Unreal Engine 4 to implement the basic functions of configuration in 2021, according to Yiming Zhong's final presentation, there is still room to improve the realism of graphics and functionality of the car configurator. Therefore, in this paper we propose to upgrade the car shaders and lighting environments according to the real-world physics and add multi-scenes switching function to car configurator. However the multi-scenes switching function also brings a large amount of data, which leads to the problem of display lag. At the end of the paper, we use the level of details(LOD) process to reduce the amount of data for real-time computing in Unreal Engine 4 and the increase of frames per second(FPS) values verifies the feasibility of our optimization solution.

      • KCI등재

        Transcriptome Analysis of Early Responsive Genes in Rice during Magnaporthe oryzae Infection

        Yiming Wang,Soon Jae Kwon,Jingni Wu,최재영,이용환,Ganesh Kumar Agrawal,Shigeru Tamogami,Randeep Rakwal,Sang Ryeol Park,김범기,정기홍,강규영,김상곤,김선태 한국식물병리학회 2014 Plant Pathology Journal Vol.30 No.4

        Rice blast disease caused by Magnaporthe oryzae is oneof the most serious diseases of cultivated rice (Oryzasativa L.) in most rice-growing regions of the world. In order to investigate early response genes in rice, weutilized the transcriptome analysis approach using a300 K tilling microarray to rice leaves infected withcompatible and incompatible M. oryzae strains. Priorto the microarray experiment, total RNA was validatedby measuring the differential expression of rice defenserelatedmarker genes (chitinase 2, barwin, PBZ1, andPR-10) by RT-PCR, and phytoalexins (sakuranetinand momilactone A) with HPLC. Microarray analysisrevealed that 231 genes were up-regulated (>2 foldchange, p < 0.05) in the incompatible interaction comparedto the compatible one. Highly expressed genes were functionally characterized into metabolic processesand oxidation-reduction categories. The oxidativestress response was induced in both early and laterinfection stages. Biotic stress overview from MapMananalysis revealed that the phytohormone ethylene aswell as signaling molecules jasmonic acid and salicylicacid is important for defense gene regulation. WRKYand Myb transcription factors were also involved in signaltransduction processes. Additionally, receptor-likekinases were more likely associated with the defenseresponse, and their expression patterns were validatedby RT-PCR. Our results suggest that candidate genes,including receptor-like protein kinases, may play a keyrole in disease resistance against M. oryzae attack

      • KCI등재

        Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus

        Yiming Shen,Seong Kyu Han,Pan Dong Ryu 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.4

        The hypothalamic paraventricular nucleus (PVN) contains two types of neurons projecting to either the rostral ventrolateral medulla (PVNRVLM) or the intermediolateral horn (IML) of the spinal cord (PVNIML). These two neuron groups are intermingled in the same subdivisions of the PVN and differentially regulate sympathetic outflow. However, electrophysiological evidence supporting such functional differences is largely lacking. Herein, we compared the electrophysiological properties of these neurons by using patch-clamp and retrograde-tracing techniques. Most neurons (>70%) in both groups spontaneously fired in the cell-attached mode. When compared to the PVNIML neurons, the PVNRVLM neurons had a lower firing rate and a more irregular firing pattern (p < 0.05). The PVNRVLM neurons showed smaller resting membrane potential, slower rise and decay times, and greater duration of spontaneous action potentials (p < 0.05). The PVNRVLM neurons received greater inhibitory synaptic inputs (frequency, p < 0.05) with a shorter rise time (p < 0.05). Taken together, the results indicate that the two pre-sympathetic neurons differ in their intrinsic and extrinsic electrophysiological properties, which may explain the lower firing activity of the PVNRVLM neurons. The greater inhibitory synaptic inputs to the PVNRVLM neurons also imply that these neurons have more integrative roles in regulation of sympathetic activity.

      • KCI등재

        Prediction on the physical properties of CuInS2 with various anion positions

        Yiming Ren,Yonghong Hu,Haibo Zeng,Li Xue 한국물리학회 2018 Current Applied Physics Vol.18 No.3

        The effects of various anion displacements (u) on electronic structures, elastic constants, Debye temperature and the minimum thermal conductivity of CuInS2 are studied by first-principles calculation. The lattice constant couples with the anion displacement, however, they are not consistent with the relation proposed by Abrahams and Bernstein. When the anion displacement varies from 0.2 to 0.3, the Cu-S bond length is elongated, while the In-S bond length is shortened, which cause the increase of band gap with anion displacement. The anisotropies of sound velocities and lattice thermal conductivities are also discussed. The results imply that the lattice thermal conductivity along [110] direction is the smallest and decreases with u. These research findings shed light on improving the thermoelectric properties by manipulating u and the direction of propagation.

      • KCI등재

        Proteasome Inhibitors Affect Appressorium Formation and Pathogenicity of the Rice Blast Fungus, Magnaporthe oryzae

        Yiming Wang,김상곤,Jingni Wu,Seok Yu,강규영,김선태 한국식물병리학회 2011 Plant Pathology Journal Vol.27 No.3

        Previously, we identified the 20S proteasome α-subunit of Magnaporthe oryzae (M. oryzae) induced during appressorium formation, and detected an increase in multiple protein ubiquitination during the early appressorium formation process (Kim et al., 2004). In this study, we further attempted to determine whether the proteasome is involved in the appressorium formation of M. oryzae both in vitro and in planta, using proteasome inhibitors. A significant increase in 20S proteasome during fungal germination and appressorium formation was observed using Western blot analysis with 20S proteasome antibody, demonstrating that proteasomemediated protein degradation was involved in appressorium formation. Pharmacological analysis using proteasome inhibitors, MG-132, proteasome inhibitor I (PI) and proteasome inhibitor II (PII) revealed that germination and appressorium formation were delayed for 4 to 6 h on rice leaf wax-coated plates. Similarly, the treatment of proteasome inhibitors with fungal conidia on the rice leaf surface delayed appressorium formation and host infection processes as well. Additionally, fungal pathogenicity was strongly reduced at 4 days’ postfungal infection. These data indicated that the fungal 20S proteasome might be involved in the pathogenicity of M. oryzae by the suppression of germination and appressorium formation.

      • KCI등재

        Adrenergic Control of Primo Tissue Size in Rats

        Yiming Shen,Yu Jeong Kim,Pan Dong Ryu 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.1

        Background: Hyperplastic morphological changes associated with erythropoiesis have been reported in the primo vascular system (PVS) tissue on the surface of abdominal organs in rats with heart failure (HF) or hemolytic anemia (HA). Objectives: Since adrenergic activity is commonly activated in both HF and HA, we investigated whether adrenergic signaling mediates the abovementioned morphological changes. Methods: We compared the effects of adrenolytic treatments (exercise training and 6-hydroxydopamine) on the gross morphology of the PVS tissues isolated from organ surfaces in HF or HA rats. HF and HA were induced by ligating the left coronary artery and injecting phenylhydrazine, respectively. We further compared the effects of norepinephrine and norepinephrine plus α- or β-adrenoceptor blockers. Results: The number of samples per rat, PN size, and proportion of red-colored samples in the PVS tissue increased in the HF and HA rats. These changes were reversed by adrenolytic treatments. Interestingly, 6-hydroxydopamine also reversed phenylhydrazineinduced hemolytic changes in erythrocytes. Subcutaneous administration of norepinephrine (3 mg/kg/d) increased the sampling frequency per rat and the PN size, but these effects were blunted at a higher dose (10 mg/kg/d). Norepinephrine administration had little effect on the proportion of red-colored tissues. Norepinephrineinduced morphological changes were completely blocked by a β-adrenoceptor antagonist (propranolol) but increased slightly by an α-adrenoceptor antagonist (phentolamine). Conclusion: Adrenergic signaling controls hyperplastic changes in the organ surface PVS in rats. These findings may explain the morphological dynamics of the PVS tissues proposed by Bong Han Kim and further clarify the pathophysiological roles of the PVS.

      • KCI등재

        Korean red ginseng excitation of paraventricular nucleus neurons via non–N-methyl-D-aspartate glutamate receptor activation in mice

        Yiming Shen,Janardhan P. Bhattarai,Soo Joung Park,Gyu Seung Lee,Pan Dong Ryu,Seong Kyu Han 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2

        It has been reported that Korean red ginseng (KRG), a valuable and important traditional medicine, has varied effects on the central nervoussystem, suggesting its activities are complicated. The paraventricular nucleus (PVN) neurons of the hypothalamus has a critical role in stressresponses and hormone secretions. Although the action mechanisms of KRG on various cells and systems have been reported, the directmembrane effects of KRG on PVN neurons have not been fully described. In this study, the direct membrane effects of KRG on PVN neuronalactivity were investigated by using a perforated patch-clamp in ICR mice. In gramicidin perforated patch-clamp mode, KRG extract (KRGE)induced repeatable depolarization followed by hyperpolarization of PVN neurons. The KRGE-induced responses were concentrationdependentand persisted in the presence of tetrodotoxin, a voltage sensitive Na+ channel blocker. The KRGE-induced responses weresuppressed by 6-cyano-7-nitroquinoxaline-2,3-dione (10 μM), a non–N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, but notby picrotoxin, a type A gamma-aminobutyric acid receptor antagonist. The results indicate that KRG activates non-NMDA glutamate receptorsof PVN neurons in mice, suggesting that KRG may be a candidate for use in regulation of stress responses by controlling autonomic nervoussystem and hormone secretion.

      • KCI등재

        Adaptive Stabilization of Feedforward Time-delay Systems with Uncertain Output Equation

        Yiming Shao,Xianglei Jia,Wenhui Liu,Guobao Liu 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.4

        In this work, the problem of global adaptive stabilization is solved by output feedback for a family of feedforward nonlinear time-delay systems with uncertain output equation and unknown growth rate. To deal with system uncertainty, a low-gain observer incorporating with novel adaptive gain is first proposed. Next, via output feedback, an adaptive delay-free controller is constructed by combining scaling change with backstepping algorithm. Compared with existing results, the controller proposed is capable of handling both uncertain output equation and unknown delay. With the aid of Lyapunov-Krasovskii functional and Barbalat ˘ ’s lemma, it is shown that the state and its estimate converge asymptotically to zero, and the adaptive gain is bounded. Furthermore, by numerical simulations, the usefulness of the control scheme is illustrated.

      • KCI등재

        Biotic Stress-Responsive Rice Proteome: An Overview

        Yiming Wang,김상곤,김선태,Ganesh Kumar Agrawal,Randeep Rakwal,강규영 한국식물학회 2011 Journal of Plant Biology Vol.54 No.4

        Biotic stresses affect the plant growth, seed quality, and crop yield. The monocot model rice crop plant is no exception and is affected by a variety of biotic stress factors. High-throughput proteomics approaches are being applied in rice for the past several years to exploit better understanding the biotic stresses-responsive regulatory mechanisms. A large number of proteins responsive to biotic stresses, including pathogens and herbivores, have been cataloged. Cataloged proteins mainly belong to functional categories into metabolism, energy, defense mechanisms, and signaling. To date, majority of these proteins have not been functionally characterized yet,except the pathogen-related 10 protein, PBZ1. This review will briefly summarize and discuss: (1) the proteomicsbased investigation of biotic stress-responsive proteins in rice and (2) increasing importance of proteomics approach in defense biology and engineering the next-generation rice/crop plants.

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