폐경전 여성에서 혈중 성호르몬결합글로불린 농도와 산화스트레스의 연관성

최영주,오지영,홍영선,성연아 대한내분비학회 2004 Endocrinology and metabolism Vol.19 No.1

연구배경: 여성에서 남성화의 간접적인 지표인 SHBG 농도는 인슐린저항성과 관련되며, 심혈관질환의 위험을 예측할 수 있는 지표로 보고되었다. 심혈관질환의 위험인자들이 산화스트레스의 증가와 관련되며, 최근 남성 호르몬의 증가와 인슐린저항성을 특징으로 하는 다낭성난소증후군 환자에서 성호르몬과 산화스트레스가 관련된다는 연구결과가 있다. 본 연구는 SHBG와 산화스트레스의 연관성을 규명하기 위하여 시행되었다. 방법: 당뇨병, 고혈압, 심혈관질환의 과거력 및 흡연력이 없는 폐경전 여성 46명을 대상으로 하여 방사 면역계수법으로 SHBG를 측정하였으며, ox-LDL은 효소면역측정법으로, TAS 및 MDA는 분광광도계로 측정하였고, SHBG와 산화스트레스를 나타내는 지표들간의 연관성을 관찰하였다. 결과: 1. 정상내당능군과 내당능장애군간에 SHBG와 MDA 농도는 유의한 차이가 없었으며, TAS는 내당능장애군에서 정상내당군에 비해 유의하게 높았다(1.41±0.15 mmol/L, 1.30±0.17 mmol/L, p=0.034). 2. SHBG 농도는 비만군에서 비비만군에 비해 유의하게 낮았다 (56.6±34.2 nmol/L, 76.0±23.8 nmol/L, p=0.036). 3. SHBG 농도는 체질량지수 (r=-0.394, p=0.007), 당부하후혈당(r=-0.326, p=0.027), 허리둘레(r=-0.323, p=0.029), 허리 대 허벅지둘레비 (r=-0.308, p=0.037), 공복인슐린 농도 (r=-0.387, p=0.008), 내장지방면적 (r=-0.339, p=0.021)과 유의한 음의 상관관계가 있었고, 인슐린 감수성지표와는 유의한 양의 상관관계(r=0.397, p=0.008)가 있었다. 4. SHBG 농도는 MDA 농도 (r=-0.357, p=0.015) 및 ox-LDL 농도 (r=-0.367, p=0.014)와 유의한 음의 상관관계가 있었다. 5. 다중회귀분석에서 연령, 체질량지수, 당부하후혈당, 허리둘레, 공복인슐린 농도, 수축기 혈압, 고밀도지 단백콜레스테롤, 중성지방을 보정한 후 SHBG 농도는 MDA 및 ox-LDL에 유의하게 독립적으로 영향을 주었다. TAS에 영항을 주는 인자로는 공복인슐린 농도와 당부하후 혈당이 통계학적으로 유의하였고, SHBG는 유의한 관련성이 없었다. 결론: 폐경전 여성에서 SHBG의 감소는 산화스트레스의 증가와 관련되어 심혈관질환의 위험을 예견할수 있는 지표로 생각된다. Background: Low levels of sex hormone-binding globulin (SHBG), an indirect index of androgenicity, are associated with insulin resistance and cardiovascular risk factors. The risk factors of the cardiovascular disease are known to be related to oxidative stress. In recent reports, sex hormones were associated with oxidative stress in women with polycystic ovarian syndrome (PCOS), which is characterized by increased androgenicity and insulin resistance. with NGT. Methods: To investigate the relationship between sex hormones and oxidative stress, we examined the association of malondialdehyde (MDA), total antioxidant status (TAS), oxidized low density lipoprotein cholesterol (ox-LDL), and SHBG in 46 Korean premenopausal women. Results: 1. SHBG and MDA levels were not significantly different among the women with NGT and IGT. But, TAS was significantly lower (p=0.034) in the subjects with IGT than in the subjects with NGT. 2. The SHBG level was significantly lower (p=0.036) in obese women than in non-obese women. 3. The SHBG level was significantly inversely correlated with BMI (r=-0.394, p=0.007), post challenge glucose (r=-0.326, p=0.027), waist size (r=-0.323, p=0.029), waist-to-thigh ratio (WTR) (r=-0.308, p=0.037), fasting insulin level (r=-0.387, p=0.008), visceral fat area (VFA)(r=-0.339, p=0.021), and was significantly positively correlated with SI (r=0.397, p=0.008). 4. The SHBG level was significantly inversely correlated with levels of MDA (r=-0.357, p=0.015) and ox-LDL (r=-0.367, p=0.014). 5. In a multiple linear regression analysis, the SHBG level was a significant and independent factor for both MDA and ox-LDL. For TAS, the fasting insulin level and post challenge glucose were significant and independent factors. Conclusion: Increased androgenicity assessed by the decrease in serum SHBG levels is associated with the increase in MDA and ox-LDL. These results suggest that increased androgenicity in premenopausal women can contribute to the development of cardiovascular diseases via increased oxidative stress (J Kor Soc Endocrinol 19:48∼57, 2004).

여성에서 Dehydroepiandrosterone sulfate와 인슐린저항성증후군의 연관성

김효정,홍은순,오지영,홍영선,성연아 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

연구배경: DHEA는 안드로겐 전구체로서 연령 증가에 따라 감소한다. 남성에서 DHEA는 인슐린저항성 및 심혈관질환에 대한 보호 작용을 하는 것으로 알려져 있으나 여성에서는 인슐린저항성과 심혈관질환에 대한 DHEA의 역할은 정립되어 있지 않다. 본 연구는 여성에서 인슐린저항성과 심혈관질환에서 DHEA의 역할을 규명하고자 시행하였다. 방법: 지역사회에서 무작위 추출된 471명의 여성을 대상으로 DHEA보다 반감기가 길고 일중 변동이 적은 것으로 알려져 있는 DHEAS의 농도를 방사면역측정법으로 측정하였다. DHEAS 농도와 인슐린저항성증후군 및 이 증후군을 구성하는 인자들과의 연관성을 관찰하였다. 결과: 1. 인슐린저항성증후군 인자의 빈도는 비만 25.3%, 내당능장애 8.5%, 고혈압 21.9%, 이상지질혈증 6.2%이었으며 인슐린저항성증후군의 빈도는 16.5%이었다. 2. DHEAS는 연령(r=-0.47, p<0.001), 수축기혈압(r=-0.18, p<0.001), 이완기혈압(r=-0.10, p<0.05), 공복혈당(r=-0.10, p<0.05), 포도당부하 2시간 혈당(r=-0.12, p<0.01), 및 중성지방(r=-0.16, p<0.01)과 의미있는 음의 상관관계가 있었다. 3. DHEAS 농도를 사분위수로 나눈 후 연령을 보정한 후 인슐린 저항성증후군 구성요소의 빈도를 관찰하였을 때 DHEAS 농도 감소에 따라 고혈압의 빈도가 유의하게 증가하였다.(p<0.05). 4. 연령(p<0.0001) 및 체질량지수(p<0.05)가 DHEAS에 영향을 주는 인자로 작용하였다. 5. 연령을 보정한 후 낮은 DHEAS농도는 인슐린저항성증후군의 위험인자로 작용하지 않았다. 결론: 여성에서 혈청 DHEAS 농도는 혈압, 혈당 및 혈청 지질 농도와 음의 상관관계가 있었으며, 연령을 보정한 후 DHEAS 농도가 감소함에 따라 고혈압의 빈도가 증가하는 것으로 보아 최소한 DHEAS는 인슐린저항성증후군에 대해 위해 작용을 가지지는 않는 것으로 생각된다. 그러나 DHEAS의 인슐린저항성증후군 및 심혈관질환에 대한 보호 작용을 증명하기 위해서는 이들 대상자를 전향적으로 추적 관찰하여 인슐린저항성증후군 및 심혈관질환의 발생과 DHEAS의 관계를 규명해야 할 것이다. Background: Dehydroepiandosterone (DHEA) is an androgen precursor, and is known to be decreased by the aging process. DHEA has been known to have a protective effect on insulin resistance and cardiovascular disease in men, but remains controversial in women. The aim of this study was to elucidate the role of DHEA on insulin resistance, and the risk for cardiovascular disease, in women. Methods: We analyzed the relationship between DHEA sulfate (DHEAS), known to have a longer half-life and less diurnal variation than DHEA, and insulin resistance syndrome (IRS) in 471 non-diabetic women from an urban community diabetes prevalence study. Serum DHEAS concentrations were measured using a commercially available radioimmunoassay kit. Results: 1. the frequencies of obesity, impaired glucose tolerance, hypertension and dyslipidemia were 25.3, 8.5, 21.9 and 6.2%, respectively, and the frequency of IRS was 16.5%. 2. DHEAS was significantly inversely correlated with age (r=-0.47, p<0.001), systolic blood pressure (r=-0.18, p<0.001), diastolic blood pressure (r=-0.10, p<0.05), fasting serum glucose (r=-0.10, p<0.05), postchllenge 2 hour glucose (r=-0.12, p<0.01) and triglycerides (r=-0.16, p<0.01). 3. As serum DHEAS concentrations, by quartiles, were decreased, the age-adjusted frequency of hypertension was significantly increase (p<0.05). 4. A Multiple linear regression analysis revealed that DHEAS was significantly associated with age (p<0.0001) and BMI (p<0.05). 5. A Logistic regression analysis showed that DHEAS was not associated with IRS after adjustment for age. Conclusion: DHEAS is inversely associated with age. DHEAS has no harmful effect, and may even have a protective role, on insulin resistance syndrome. Prospective examinations of DHEAS and insulin resistance syndrome in women are needed to confirm the mechanism for the association between DHEAS and the development of cardiovascular disease (J Kor Soc Endocrinol 17:675∼684, 2002).

Analysis of the width ratio and wear rate of maxillary anterior teeth in the Korean population

Oh, Yeon-Ah,Yang, Hong-So,Park, Sang-Won,Lim, Hyun-Pil,Yun, Kwi-Dug,Park, Chan The Korean Academy of Prosthodonitics 2017 The Journal of Advanced Prosthodontics Vol.9 No.2

PURPOSE. The purpose of this study was to compare the width ratio of maxillary anterior teeth according to age in the Korean population and to evaluate the maxillary central incisor width-to-length (W/L) ratio, given differences in age and gender. MATERIALS AND METHODS. Ninety-three Korean adults were divided into 3 groups (n = 31) by age. Group I was 20 - 39 years old, Group II was 40 - 59 years old, and Group III was over 60 years of age. After taking an impression and a cast model of the maxillary arch, the anterior teeth width ratio and central incisor W/L ratio were calculated from standard digital images of the cast models using a graph paper with a digital single lens reflex (DSLR) camera. The calculated ratios were compared among all groups and central incisor W/L ratio were analyzed according to age and gender. All comparative data were statistically analyzed with one-sample t-tests, one-way ANOVAs with Tukey tests, and independent t-tests. RESULTS. No significant differences in maxillary anterior teeth ratios were found among the age groups. The maxillary central incisor W/L ratios in Group III were the greatest and were significantly higher than those in the other groups. The central incisor W/L ratio of men was higher than that of women in Group II. CONCLUSION. Maxillary anterior teeth width ratios were similar in all age groups in the Korean population. The maxillary central incisor was observed as worn teeth in the group over 60 years of age, and a significant difference between genders was found in 40 to 50 year olds.

A Research on the Analysis of Characteristics of Environmental Experience in Early Childhood and Recent years

Ah-yeon Oh,Yeonsook Lee,Yea-ji Lim,Ji-young Lee 한국주거학회 2015 한국주거학회 국제학술대회논문집 Vol.2015 No.4

Analysis of the width ratio and wear rate of maxillary anterior teeth in the Korean population

Yeon-Ah Oh,Hong-So Yang,Sang-Won Park,Hyun-Pil Lim,Kwi-Dug Yun,Chan Park 대한치과보철학회 2017 The Journal of Advanced Prosthodontics Vol.9 No.2

PURPOSE. The purpose of this study was to compare the width ratio of maxillary anterior teeth according to age in the Korean population and to evaluate the maxillary central incisor width-to-length (W/L) ratio, given differences in age and gender. MATERIALS AND METHODS. Ninety-three Korean adults were divided into 3 groups (n = 31) by age. Group I was 20 - 39 years old, Group II was 40 - 59 years old, and Group III was over 60 years of age. After taking an impression and a cast model of the maxillary arch, the anterior teeth width ratio and central incisor W/L ratio were calculated from standard digital images of the cast models using a graph paper with a digital single lens reflex (DSLR) camera. The calculated ratios were compared among all groups and central incisor W/L ratio were analyzed according to age and gender. All comparative data were statistically analyzed with one-sample t-tests, one-way ANOVAs with Tukey tests, and independent t-tests. RESULTS. No significant differences in maxillary anterior teeth ratios were found among the age groups. The maxillary central incisor W/L ratios in Group III were the greatest and were significantly higher than those in the other groups. The central incisor W/L ratio of men was higher than that of women in Group II. CONCLUSION. Maxillary anterior teeth width ratios were similar in all age groups in the Korean population. The maxillary central incisor was observed as worn teeth in the group over 60 years of age, and a significant difference between genders was found in 40 to 50 year olds.

자연 유산에서 드물게 관찰된 Jumping translocation 2례

이연우(Yeon Woo Lee),이봄이(Bom Yi Lee),박주연(Ju Yeon Park),최은영(Eun Young Choi),오아름(Ah Rum Oh),이신영(Shin Young Lee),류현미(Hyun Mee Ryu),강인수(Inn Soo Kang),양광문(Kwang Moon Yang),박소연(So Yeon Park) 대한의학유전학회 2010 대한의학유전학회지 Vol.7 No.1

Jumping translocation (JT)은 여러 세포주에서 하나의 공여 염색체가 둘 이상의 수여 염색체와 염색체 재배열을 보이는 염색체의 구조적 이상으로 종양 세포인 림프성 혈액암에서 빈번하게 관찰되는 획득성(acquired) JT에 비해 체질성(con-stitutional) JT는 매우 드물게 보고되고 있다. 본 증례에서는 자연 유산된 수태산물에서 관찰된 체질성 JT 2례를 보고하고자 한다. 증례 1은 임신 7주 유산아 조직의 세포유전학적 검사에서 핵형분석 결과는 46,XY,add(18)(p11.1)[61]/45,XY,der(18;21)(q10;q10)[32]/46,XY,-18,+mar[16]/46,XY,i(18)(q10)[9]/45,XY,der(15;18)(q10;q10)[6]/46,XY,+1,dic(1;18)(p22;p11.1)[2]/45,XY,der(13;18)(q10;q10)[1]/46,XY[32]로 관찰되었다. 공여 염색체는 18번이고 수여 염색체는 1, 13, 15, 18, 21번이었다. 증례 2는 임신 6주째 자연 유산된 유산아 조직으로부터 세포 유전학적 검사를 실시한 결과, 핵형은 46,XY,der(22)t(9;22)(q12;q13)[22]/46,XY,der(22)t(1;22)(q21;q13)[13]/46,XY,add(22)(q13)[5]/46,XY[23]고 관찰되었다. 공여 염색체는 22번이고 수여 염색체는 1, 9번이었다. 2례 모두 de novo였고 acrocentric 염색체를 수반하였으며 절단점은 대부분 중심절과 중심절 주위, 말단체에 존재하였다. 본 증례는 매우 드물게 관찰되는 체질성 JT로서 임신 초기 세포 분열 단계에서 발생했고 다양한 세포주에서 나타난 비정상 핵형으로 인해 정상적인 배발달이 이루어지지 못하여 자연 유산된 것으로 생각된다. Jumping translocations (JT) are chromosomal rearrangements involving one donor chromosome and several recipient chromosomes. While JTs are frequently observed as acquired chromosomal abnormalities in hematologic malignancies, constitutional JTs are only rarely reported. We report two cases of constitutional JT in chorionic villi derived from the products of conception. The karyotype of the first case was 46,XY,add(18)(p11.1)[61]/45,XY,der(18;21)(q10;q10)[32]/46,XY,-18,+mar[16]/46,XY,i(18)(q10)[9]/45,XY,der(15;18)(q10;q10)[6]/46,XY,+1,dic(1;18)(p22;p11.1)[2]/45,XY,der(13;18)(q10;q10)[1]/46,XY[32]. The donor was a chromosome 18. The recipient chromosomes were chromosomes 1, 13, 15, 18 and 21. In the second case, the karyotype was 46,XY,der(22)t(9;22)(q12;q13)[22]/46,XY,der(22)t(1;22)(q21;q13)[13]/46,XY,add(22)(q13)[5]/46,XY[23]. The donor was a chromosome 22 and recipients were chromosomes 1 and 9. Both cases were de novo. The breakpoints of chromosomes were mostly in centromeric regions, pericentromeric regions, or telomeric regions. Normal cell lines were observed in both cases. This report supports the prior findings that the unstable nature of JT, resulting in chromosomal imbalance, most likely contributed to these early miscarriages.

재외동포 현지 교과로서의 ‘조선어’ 교과의 복합적 위상 분석 연구를 위한 시론

오현아(Oh, Hyeon-ah),오지혜(Oh, Ji-hye),진가연(Jin, Ka-yeon),신명선(Sin, Myeong-seon) 국어국문학회 2016 국어국문학 Vol.- No.177

이 연구에서는 재외동포 현지 교과인 ‘조선어’ 교과의 복합적 위상을 ‘모국어 교과’, ‘분단 상황에서의 중간자적 언어 교과’, ‘재외동포 현지 교과’ 차원으로 구분하여 그 실태를 종합적으로 파악하여 비교·분석하는 연구의 필요성을 제기하고자 하였다. 첫째, ‘조선어’ 교과는 ‘모국어 교과’로서의 위상을 지닌다. 중국 내 공용어로서의 ‘중국어’와 모국어인 ‘조선어’의 위상에 관한 것으로, 이를 위해서는 먼저 공용어인 ‘중국어’와 모국어인 ‘조선어’에 대한 조선족의 인식 실태 조사를 학생, 학부모, 교사, 교육 행정가 등을 대상으로 실시해 볼 필요가 있다. 그리고 조선어 교육과정과 교과서의 사적 고찰을 통해 ‘조선어’ 교육이 어떠한 변화를 겪어왔는지에 대해 분석해 볼 필요가 있다. 이러한 현지 모국어 교육의 역사적 기술은 북미, 일본, 러시아 지역의 현지 모국어 교육의 역사적 기술로 확장될 가능성이 농후하다고 할 수 있다. 둘째, 조선어 교과는 ‘분단 상황에서의 중간자적 언어 교과’로서의 위상을 지닌다. 개혁 개방, 중․한 수교 이전 중국의 조선어 교육은 실제적으로 북한어의 영향을 많이 받아왔으나 개혁 개방, 중․한 수교 이후에는 남한어의 영향이 점차 증가하는 방향으로 진행되어 왔다. 따라서 ‘북한어’와 ‘남한어’ 사이의 ‘조선어’에 대한 조선족의 인식 실태 조사를 학생, 학부모, 교사, 교육 행정가 등을 대상으로 실시해 볼 필요가 있다. 그리고 남북한의 교육과정과 교과서와의 비교 고찰을 통해 조선어 교육에서의 남한의 국어교육과 북한의 국어교육의 영향 관계를 분석해 볼 필요가 있다. 이를 통해 특정 시기 재외동포의 현지 모국어 교육의 역사적 기술이 가능하며, 현재 ‘남한어’와 ‘북한어’ 사이 ‘조선어’의 중간자적 지정학적 위상을 명확히 파악할 수 있을 것으로 기대된다. 셋째, 조선어 교과는 ‘재외동포 현지 교과’로서의 위상을 지닌다. 현재 국립국제교육원, 재외동포재단 등에서 재외동포 대상의 한국어교육을 위한 교재들을 배포하고 있으며, 온라인 학습콘텐츠를 제공하고 있다. 그러나 현지 사정을 고려하지 못한 공급자 중심의 교재 제작으로 이들은 현지에서 제대로 활용되고 있지 못하다. 따라서 재외동포용 한국어 교재 개발에 참여했거나 한국어교육의 실행 주체인 한국어 교사를 대상으로 ‘한국어’에 대한 한국어교육 전문가의 인식 조사가 진행될 필요가 있다. 이를 통해 향후 재외동포를 위한 한국어 교재 개발의 제안 사항이나 주의 사항을 도출해낼 수 있을 것으로 기대된다. In this study, the complex status of ‘the Joseon language’ curriculum, which is a local curriculum of overseas Koreans, is divided into ‘the native language subject,’ ‘the mediator language subject in the divisional situation’ and ’the local language subject for overseas Koreans’ and this study attempted to comprehensively examine the actual status to raise the need for research of comparison and analysis. First, ‘the Joseon language’ has a status as a ‘native language subject.’ It is necessary to check the status of ‘Chinese’ as the official language in China and ‘the Joseon language’ as the mother tongue. For this purpose, it is necessary to conduct a survey on Korean‐Chinese’s perception of “the Chinese language” as the official language and “the Joseon language” as the mother tongue to students, parents, teachers and educational administrators. And it is necessary to analyze what kind of changes ‘the Joseon language education’ has undergone through the chronological study of Joseon language curriculum and textbooks. It is possible that the historical descriptions of the local native language education are likely to expand to those of the local native language education in North America, Japan and Russia. Second, the Korean language subject has a status as ‘a mediator language subject in the situation of division.’ The Korean language education in China before China’s reform, opening and signing a treaty of amity with Korea was actually influenced by the North Korean language. However, it can be said that after China’s reform, opening and signing a treaty of amity with Korea, the Korean language education in China has been influenced by the South Korean language gradually. It is necessary to conduct a survey on Joseon people’s perception of ‘the Joseon language’ in between ‘North Korean’ and ‘South Korean’ for students, parents, teachers, and education administrators. It is necessary to analyze the influencing relationships between South Korean language education and North Korean language education through a comparative study with the curriculum and textbooks of North and South Korea. Through this, it is possible to historically describe the local native language education for overseas Koreans at a certain time, and it is expected that it can clearly grasp the mediator geopolitical status of ‘the Joseon language’ between ‘South Korean’ and ‘North Korean.’ Third, the Joseon language curriculum has a status as a ‘local curriculum for overseas Koreans.’ Currently, the National Institute for International Education and the Overseas Koreans Foundation are distributing teaching materials for Korean language education for overseas Koreans and provide online learning contents. However, it is not well utilized locally due to the supplier‐oriented textbook production that does not consider local circumstances. Therefore, it is necessary to investigate Korean language education specialists’ recognition of ‘the Korean language’ who have participated in the development of Korean textbooks for overseas Koreans or who have been involved in the Korean language education. It is expected that it will be able to derive suggestions and cautions for the development of Korean textbooks for overseas Koreans in the future.

취약계층 지원주택 계획을 위한 주민참여디자인워크샵 의의

오아연(Oh, Ah-Yeon),이연숙(Lee, Yeun-Sook),김윤수(Kim, Yun-Su),박지선(Park, Ji-Seon) 한국실내디자인학회 2016 한국실내디자인학회 학술대회논문집 Vol.2016 No.05

In case of Korea where numerous houses have been supplied in short time due to rapid industrialization of its societies, as it had no time to have various considerations in proportion tosuch rapid speed, stereotype houses have been supplied massively. However, now it is time to supply qualitative housing after the long period of quantitative housing supplies. Furthermore, Korea confronts an era that it should seriously consider how quality of life can be improved through paradigm change. What is more, in case of its socially disadvantaged people, their opinions have not been reflected owing to top down housing supply method, thus causing diverse problems. It is necessary the dwelling should reflect the needs of prospect in gusers through their participation. The purpose of this study was to share the process of developing the public rental housing for the low income families with the participation of residents in the local community. The house was not conventional collective housing but supportive housing, thus needs the resident’s participation more necessarily. As method of study, user participated workshops were used. Houses developed through this process prevented and resolved the possible doubts and conflictions among the stakeholders. It is expected that the results of this study will contribute a lot to change the direction of housing supplies through housing development process that prevents the conflicts prior to construction and promotes there liability and trust transparent communication and two-way design process reflecting the residents’ opinions.

우수 지원주택 사례를 통해 본 취약계층 주거공간의 적정 규모

오아연(Oh, Ah-Yeon),장미선(Jang, Mi-Seon),이연숙(Lee, Yeun-Sook) 한국주거학회 2016 한국주거학회 학술대회논문집 Vol.28 No.2

지원주택 사례에 나타난 치유디자인특성 분석

오아연(Oh, Ah-Yeon),이연숙(Lee, Yeun-Sook),장미선(Jang, Mi-Seon) 한국실내디자인학회 2016 한국실내디자인학회 학술대회논문집 Vol.2016 No.10

People in the vulnerable social class is exposed to harmful environments to their health so that their physical and psychological health may deteriorate easily and their quality of life may also deteriorate due to their financial difficulties and social alienation. Supportive housing needs to reflect the characteristics of healing residents through normal residential environments in comparison to other facilities or spaces. Therefore, the purpose of this study is to analyze the characteristics of healing design reflected in the cases of supportive housing. For such purpose, supportive housings among the winners of Top Ten Projects selected by the affiliated committee of the American Institute of Architects were selected primarily and 4 supportive housings targeting the elderly or the disabled that were expected to reflect the characteristics of healing design more were selected finally and the case analysis was carried out targeting the finally selected supportive housings. Unlike the precedent studies that discussed only healing characteristics in physical, psychological and social health aspects, the result of case analysis showed that the design characteristics related to economic health were reflected in the supportive housing cases in addition to 3 health characteristics discussed in the precedent studies. It is expected that the result of this study will be utilized as preliminary data for the establishment of environments for improving the healing performance of supportive housing through the analysis of characteristics of healing design reflected at the time of planning the supportive housing.