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박성봉,김영미,전성일,이기철,김영훈,정영조,이영렬,이정호,최영민 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6
목 적 : 정 신분열병 환자의 자기만입 정도에 영향을 미치는 인구학적 변인들 및 질병연관 변인들을 규명해 보고자 하였다. 또한. 환자들의 자기만입과 병식 사이의 연관성. 자기만입과 자존심 사이의 연관성을 알아보고자 하였다. 방 법 : 정신과 의사가 병록지와 면담을 통하여 대상 정신분열병 환자들의 인구학적 변인들 및 질병연관 변인들에 관한 자료를 얻고 환자들의 병식 정도를 평가한 후, 환자들로 하여금 자기보고형의 자기만입 척도와 자존심 척도를 시행하게 하였다. 총 111명의 환자가 연구대상으로 선택되었다. 결과: . 1) 여자가 남자보다 유의하게 높은 자기만입 척도 점수를 나타내었다 2) 질병연관 변인들 중 하위집단 사이에 자기만입 척도 점수의 유의한 차이를 보이는 변은 없었다. 3) 자기만입 척도 점수와 병식 점수 사이에 유의한 상관관계가 없었다. 4) 자기만입 척도 점수와 자존심 척도 점수 사이에 유의한 역상관 관계를 보였다. 결 론 : 본 예비 연구의 결과로 보아 정신분열 병 환자의 병식이 부족한 상태에서도 자기만입이 진행될 수 있으며. 자기만입이 심할수록 환자의 자존심이 저하되는 것으로 생각된다. 또한 여자 환자들이 남자 환자들보다 자기만입에 더 취약한 것으로 생각된다. 따라서 정신분열 병 환자의 이해와 치료를 위하여 자기만입에 관한 지속적인 연구가 필요할 것으로 생각된다. objective : This study was conducted to identify demographic variables and illness related variables which may affect the severity of self-engulfment in the patients with schizophrenia. We also studied the relationship between self-engulfment and insight, and the relationship between self-engulfment and self-esteem. Methods : Data on demographic variables and illness related variables for the subjects were gathered from hospital records and clinical interviews by the psychiatrists. Degree of insight for the subjects was assessed through clinical interviews by the psychiatrists. Degree of self-engulfment and self-esteem for the subjects was assessed from the self-engulfment scale and the self-esteem scale respectively. A total of 111 patients with schizophrenia were selected for statistical analysis. Results 1) The females exhibited significantly higher scores than the males on the self-engulfment scale. 2) There was no illness related variable, which exhibited a significant difference among subgroups on the self-engulfment scale. 3) There was no significant correlation between the self-engulfment scores and the insight 4) There was a significantly inverse correlation between the self-engulfment scores and the self-esteem scores. Conclusion : The results of this preliminary study suggest that self-engulfment may develop despite lack of insight and that there was inverse relationship between self-engulfment and self-esteem in the patients with schizophrenia. It also suggests that females are more subject to self-engulfment than males. So, authors suggest that it is valuable to do further studies of self-engulfment in the patients with schizophrenia.
최기훈 ( Gi Hoon Choi ),최광민 ( Goang Min Choi ),김형수 ( Hyoung Soo Kim ),조성준 ( Seong Joon Cho ),류세민 ( Se Min Ryu ),안희철 ( Hee Cheol Ahn ),서정열 ( Jeong Yeol Seo ) 대한결핵 및 호흡기학회 2006 Tuberculosis and Respiratory Diseases Vol.61 No.5
연구배경: 농흉을 치료하는데 VATS가 도입된 후 VATS의 유용성에 대해 많은 연구의 결과들이 보고 되고 있으며 실제로 치료 프로토콜에도 변화를 가져 왔으나 아직까지는 문헌상의 보고가 양적으로 충분하지 못하며 기존의 치료방법에 비해 VATS의 장점 역시 명확하게 검증되어 있지 못한 상태이다. 방법: 의무기록과 흉부 방사선 사진을 검토하여 기존의 치료 환자 군과 VATS 환자 군을 비교하였다. 2001년 1월부터 2003년 12월까지 한림대학교 춘천성심병원에 농흉으로 입원하여 기존의 방법으로 치료받은 환자들을 A군으로 하고 2003년 12월부터 2006년 8월까지 농흉으로 흉강경 수술을 받은 환자들을 B군으로 나누어 입원기간, 흉관 유지 기간, 백혈구증가증이 있던 기간, 발열이 있던 기간, 항생제 사용기간을 비교하였다. 그리고 흉막비후, 갈비가로막각이 각각 치료 전후 어떻게 변하였는지 비교하여 보았다. 결과: A군은 15명으로 남자가 11명 여자가 4명이었고, 평균 나이는 58.2±15.7세 이었고, B군은 11명으로 남자가 9명, 여자가 2명이었으며 평균 나이는 51.6±9.5세 이었다. B군에서 입원 기간(16.6±7.4일, A군은 33.7±22.6일; p=0.014)과 흉관 유지 기간 (10.5±5.7일, A군은 19.5±14.4; p=0.039), 백혈구증가 기간(6.7±6.5일, A군은 18.8±13.2일; p=0.008), 발열 기간(0.8±1.8일, A군은 9.4±9.2일; p=0.004), 항생제 사용기간 (B군 14.9±6.4일, A군 25.4±13.9일; p=0.018)이 A군에서보다 통계적으로 유의하게 감소하였다. 그러나 흉막비후, 갈비가로막의 둔함의 정도는 통계적으로 유의한 변화는 없었다. 결론: 농흉에서 흉강경을 이용한 치료를 하면 기존의 방법에 비해 입원 기간, 흉관 유지기간, 백혈구증가증 기간, 발열 기간, 항생제 사용기간을 단축시킬수 있어 환자의 증상을 더 빨리 개선시키며, 흉관을 조기에 제거할 수 있고 입원기간을 단축시킨다. Background: Since video-assisted thoracoscopic surgery (VATS) was introduced as a new treatment modality for empyema thoracis, numerous reports have suggested that VATS is a more effective treatment method than the traditional methods that mainly use antibiotics and drainage apparatus. However, no confirmative evidence of the superiority of VATS over the traditional method has been provided yet. Methods: We attempted to evaluate the efficacy of VATS for the treatment of empyema thoracis by reviewing past medical records and simple chest films. First, we divided the patients into two groups based on the treatment method: group A of 15 patients who were treated with the traditional method between January 2001 and December 2003, and group B of 9 patients who were treated with VATS between December 2003 and August 2006. The final outcomes used in this study were the number of days of hospital stay, chest tube duration, leukocytosis duration, febrile duration, and intravenous antibiotics usage duration. In addition, radiological improvements were compared. Results: The mean age(±standard deviation) of 11 men and 4 women in group A was 58.2±15.7 years, and of 9 men and 2 women in group B was 51.6±9.5 years. Group B had a significantly shorter hospital stay (16.6±7.4 vs. 33.7±22.6 days; p=0.014), shorter chest tube duration (10.5±5.7 vs. 19.5±14.4 days; p=0.039), shorter leukocytosis duration (6.7±6.5 vs. 18.8±13.2 days; p=0.008), shorter febrile duration (0.8±1.8 vs. 9.4±9.2 days; p=0.004), and shorter duration of intravenous antibiotics usage (14.9±6.4 vs. 25.4±13.9 days; p=0.018). However, radiological improvements did not show any statistical differences. Conclusion: Early application of VATS for empyema thoracis treatment reduced hospital stay, thoracostomy tube duration, leukocytosis duration, febrile duration, and antibiotics usage duration in comparison with the traditional methods. The early performing of VATS might be an effective treatment modality for empyema thoracis. (Tuberc Respir Dis 2006; 61: 463-472)
최기훈 ( Gi Hun Choi ),서정열 ( Jeong Yeol Seo ),안무업 ( Moo Eob Ahn ),안희철 ( Hee Cheol Ahn ),김성은 ( Sung Eun Kim ),천승환 ( Seung Hwan Cheun ),이승용 ( Seung Yong Lee ),최광민 ( Kwang Min Choi ),김형수 ( Hyung Soo Kim ),정 대한외상학회 2006 大韓外傷學會誌 Vol.19 No.2
Tricuspid regurgitation after blunt chest trauma is rarely seen in the emergency department. A 19-year-old patient visited our emergency department with chest discomfort after collision with his brother while skiing. Recently, Skiing as a winter sports has become popular with the Korean people, so there is an increasing tendency for patients with diverse traumas associated with ski accidents to visit the emergency department. From simple abrasions or contusions to deadly injuries with unstable vital signs, we are seeing many kind of injuries in the emergency department. We present the case report of a patient with tricuspid regurgitation after a blunt chest trauma during the skiing. (J Korean Soc Traumatol 2006;19:188-191)
Choi, Joon-Phil,Shin, Gi-Hun,Brochu, Mathieu,Kim, Yong-Jin,Yang, Sang-Sun,Kim, Kyung-Tae,Yang, Dong-Yeol,Lee, Chang-Woo,Yu, Ji-Hun JAPAN INSTITUTE OF METALS 2016 MATERIALS TRANSACTIONS Vol.57 No.11
<P>Selective laser melting (SLM) is an attractive manufacturing technique for the production of metal parts with complex geometries and high performance. This manufacturing process is characterized by highly localized laser energy inputs during short interaction times which significantly affect the densification process. In this present work, experimental investigation of fabricating 316L stainless steel parts by SLM process was conducted to determine the effect of different laser energy densities on the densification behavior and resultant microstructural development. It was found that using a low laser energy density below 50 J/mm(3) produced an instable melt pool that resulted in the formation of unmelted particles, pores, cracks, and balling in the as-built parts with low densification. In contrast, the as-built parts at a high energy density above 200 J/mm(3) showed irregular scan tracks with a number of pores and metal balls that decreased part density. The optimal laser energy density range was accordingly determined to be 58-200 J/mm(3) by eliminating obvious SLM defects, which led to near full densification. The SLM samples fabricated using optimal parameters allowed observation of a microhardness of 280 Hv, ultimate strength of 570 MPa, and yield strength of 530 MPa that were higher than those of the as-cast and wrought 316L stainless steel.</P>
Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
Choi, Bong-Kyu,Choi, Mal-Gi,Kim, Jae-Yeol,Yang, Yoosoo,Lai, Ying,Kweon, Dae-Hyuk,Lee, Nam Ki,Shin, Yeon-Kyun National Academy of Sciences 2013 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.110 No.10
<P>Parkinson disease and dementia with Lewy bodies are featured with the formation of Lewy bodies composed mostly of α-synuclein (α-Syn) in the brain. Although evidence indicates that the large oligomeric or protofibril forms of α-Syn are neurotoxic agents, the detailed mechanisms of the toxic functions of the oligomers remain unclear. Here, we show that large α-Syn oligomers efficiently inhibit neuronal SNARE-mediated vesicle lipid mixing. Large α-Syn oligomers preferentially bind to the N-terminal domain of a vesicular SNARE protein, synaptobrevin-2, which blocks SNARE-mediated lipid mixing by preventing SNARE complex formation. In sharp contrast, the α-Syn monomer has a negligible effect on lipid mixing even with a 30-fold excess compared with the case of large α-Syn oligomers. Thus, the results suggest that large α-Syn oligomers function as inhibitors of dopamine release, which thus provides a clue, at the molecular level, to their neurotoxicity.</P>
Anti-neuroinflammatory Effect of the Ethanolic Extract of Aster koraiensis Nakai
Gi Hwan Lee(이기환),Kwan Woo Kim(김관우),Chang Yeol Yang(양창열),Dae Young Lee(이대영),Da Hye Yoon(윤다혜),Yoon Ji Lee(이윤지),Je Seung Jeon(전제승),Je Hun Choi(최재훈),Geum Soog Kim(김금숙),Young Seob Lee(이영섭) 한국약용작물학회 2023 한국약용작물학회 학술대회논문집 Vol.2023 No.1
Perpendicular Magnetization of CoZr/Pt Multilayers
길준표,Gi Yeol Bae,서동익,박완준,Won Joon Choi,Jae Sung Noh 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.10
Recently, perpendicular magnetization of tunnel junctions has been proposed as a way to reduce the size of spin-transfer torque random access memory. In order to determine the free layer of a magnetic tunnel junction, we present a Co(90)Zr(10) alloy which is expected to have higher polarization than any other soft magnet. At a thickness of 0.6 nm, CoZr successfully forms perpendicular magnetization using interfacial anisotropy on CoZr/Pt interfaces. Unlike the Co/Pt multilayer, the CoZr/Pt multilayer shows magnetization recovery following 1.5 T field cooling after 300 ℃ annealing since the Zr insertion prevents the formation of a CoPt alloy. This work proposes CoZr as a free layer candidate for magnetic tunnel junctions due to its advantages of lower switching current and higher thermal stability.