마우스 대장암 모델 구축 및 항암제 활성 평가를 위한 예비 연구

김예솔,강봉석,이상은,이은주,이경록,정상헌,박정숙 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

Abstract – Aberrant crypt foci (ACF) are early imorphological changes observed in rodents after administration of colon-specific carcinogen such as azoxymethane (AOM). ACF are considered to be putative preneoplastic lesions and are widely used as a surrogate biomarker to rapidly evaluate chemopreventive potential of compounds. The size of colorectal cancer was evaluated after administration of three anticancer drugs, 1 parent drug and 2 prodrugs. The body weights of mice were measured daily and considered as a surrogate for evaluation of general wellbeing. Colons were removed, cut along the longitudinal axis and flushed with phosphate-buffered saline. Each colon was cut into three equal lengths and fixed flat between filter papers. The fixed colon sections were stained with methylene blue. The number of ACF per colon, the number of aberrant crypts observed in each focus and the location of each focus were recorded. After single administration of AOM and multiple doses of anticancer drugs, no significant changes in the body weights of the mice was observed which was recorded for 52 days. However, an expected ACF was not observed in any treated groups. These findings suggest the induction of ACF in mice requires the promotion by dextran sulfate sodium as well as the initiation by AOM.

건식과 습식 반탄화 바이오매스의 화학적 구조적 특성

이은주,정수아,정예진,형세진,이재원 전남대학교 농업과학기술연구소 2022 농업생명과학연구동향 Vol.60 No.-

The study analyzed the physical and chemical properties of dry-torrefied (DT) and wet-torrefied (WT) biomass. Hemicellulose was mainly degraded by torrefaction, and the contents of glucan and lignin were relatively increased. The degradation rate of biomass was higher in WT (18.25%–23.13%) than in DT biomass (3.12%–3.83%), and it increased with increasing reaction time. Torrefaction improved the crystallinity of the biomass from 36.88% in the raw material to a maximum value of 60.97% in the biomass subjected to wet torrefaction for 30 min (WT-30). The thermal stability of torrefied biomass was improved in WT-10 (17.21%), WT-60 (15.38%), and DT-60 (8.74%) compared to that of the raw material (2.35%). The hydrophobicity and fine particle distribution of biomass were increa- sed by torrefaction, with the lowest water absorption (3.08%) and the highest distribution of fine particles (8.20%) being observed in WT-60 biomass.

제품유형과 광고의 불일치성이 광고와 제품평가에 미치는 영향 : 제품유형과 광고의 상호작용 효과를 중심으로

예종석,이은정,김균 한국방송광고공사 2005 광고연구 Vol.0 No.69

소비자 의사 결정과정에 대한 정보를 제공하는 커뮤니케이션은 마케팅이나 광고전략에 있어서 중요한 역할을 한다. 다양한 마케팅 커뮤니케이션 도구들이 개발되면서 마케터들은 과다한 정보를 제공하게 되었고 제한된 소비자들의 관심을 끌기 위해 수많은 사람들과의 경쟁에 합류하게 되었다. 이에 대한 해결책의 일환으로 불일치한 광고에 대한 연구가 진행되었다. 따라서 본 연구에서는 제품을 구매의도에 따라 쾌락적 제품과 실용적 제품으로 분류하고 광고의 불일치성이 각 제품유형에 미치는 영향을 비교 평가하였다. 연구결과 기대·관련 - 비기대·관련 광고의 광고평가에 대한 차이에서는 느낌, 공감, 신뢰, 제품 평가에 대한 도움이 제품별 차이가 유의한 것으로 나타났으며, 기대·관련 - 기대·비관련 광고의 광고평가에 대한 차이에서는 신뢰, 유익, 제품평가에 대한 도움이 제품별 차이가 있는 것으로 나타났다. 또한 기대·관련 - 비기대·비관련 광고의 광고평가에 대한 차이에서는 느낌, 공감, 설득이 제품별 차이가 있는 것으로 나타났다. 본 연구는 이와 같이 태도와 설득에 관한 연구에 기초하여 광고의 불일치성을 기대성과 관련성이라는 개념으로 구분하여 소비자들이 느끼는 광고와 제품평가, 구매의도를 실증적으로 연구하였다. 또한 태도의 다중 구성 요소 이론을 제품의 구매동기에 따른 제품형태로 확장하여 새로운 영역의 발전을 시도하였으며, 서로 다른 불일치 차원에서 소비자들의 반응의 차이를 구하여 제품별로 비교 평가하였다. The purpose of this study is to classify products into hedonic products and utilitarian products by intention to purchase, and to compare and evaluate effects of inconsistency of advertisement on product types. The results of this study shown that concerning the expectation and the relevance of advertisement, there was significant difference in the advertisement evaluation, product evaluation, and intention to purchase partially. This study can be considered to be significant academically in terms of classifying inconsistency of advertisement into “expected” and “relevant” and examining customers’ response against advertisement, product evaluation, and intention to purchase empirically on the basis of studies on attitude and persuasion. And, this study had academic significance as it was attempted to develop the new field of studies by extending multi components theory of customers’ attitude into product type by purchase motive of products, and to examine difference in consumers’ response in different level of inconsistency and to compare and evaluate by products.

근피로 후 세 가지 회복 방법

이예영,김지은,서예은,정다연,강현주 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

Muscle fatigue is a symptom that decreases your muscles’ ability to perform over time. It can be associated with a state of exhaustion, often following excessive sports activity or exercise. While exercise is a common cause of muscle fatigue, this symptom can be the result of other health conditions. Muscle fatigue caused by excessive activity limits activities of daily living and difficult to maintain a stable posture. Therefore, the purpose of this study was to investigate the effect of stretching, icing, and sports massage on muscle fatigue recovery.

박물관 브랜드 마케팅 및 공간 프로모션 전략 -숙명여자대학교 내 정영양자수박물관 C·E·M 공간디자인을 중심으로-

김은애,김예은,정채림,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 정영양자수박물관의 콘텐츠를 활용한 통합 브랜드를 개발함에 있어 브랜드·디자인 ·마케팅을 융합한 시점에서 바라보고 그래픽아이덴티티, 제품아이덴티티, 공간아이덴티티 통합브랜드를 구축하는 일련의 프로세스를 밝히는데 목적이 있다. 이에 본 연구는 기존의 박물관 방문자들과 20-30대 여성을 대상으로, 디자인과 마케팅의 융합된 측면에서 도출된 ‘C·E·M’을 物, 事, 人, 場가 융합된 문화로 한정한다. 그 결과, ‘C·E·M’은 디자인과 마케팅 전략을 융합하여 로고 및 사인물의 그래픽디자인부터 제품디자인, 공간디자인에 이르기까지 일관성과 객관성, 스토리성을 도출한다. 끝으로 본 연구는 브랜드가 디자인과 마케팅을 융합하여 더 체계화된 G·I, P·I, S·I의 통합 브랜드 매뉴얼을 만든 것에 의의가 있다. 아울러 향후 이와 관련된 통합브랜드 디자인 개발에 있어서 기초 자료로 활용될 것으로 기대된다

태권도 옆차기 동작의 우수자와 비우수자간의 운동학적 비교 분석

이호진,한재희,김륜건,홍예은,우상연 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

The purposes of this study were to analyze the kinematic variations between skilled and unskilled individuals and obtain the data needed to improve effective side kick skill in Teakwondo. We used a video analysis program to collect performance time, changes in movement of the center of the body, angle, and angular velocity. The results were as follows : 1) in unskilled cases, side kick motion occurred for more time than in unskilled cases, 2) to make a stronger kick, the skilled group increased the joint speed of the legs and unskilled athletes have smaller angles than experienced athletes. As a result, the total performance time of side kicks was shorter for skilled people and was consistent with other previous studies. The angle of the knee joint and hip joint had a great influence on the side kick.The range of motion of the hip and knee joints should be increased so that the desired hitting point can be quickly reached.

노인과 대학생의 낙상 위험 분석

정다현,김예희,김지은,이예영,강현주 순천향대학교 기초과학연구소 2021 순천향자연과학연구 논문집 Vol.27 No.1.2

The purpose of this study was to analyze risk of falls between elderly people and college students. The subjects of this study were 25 people aged 70 years or older and 17 college students located in Asan. We measured sensory, integrated balance, nervous, musculoskeletal system and HQR by FRA system (Inbody, Korea). The results of measurement showed significant differences in sensory system (p<.01), integrated balance (p<.001), nervous system (p<.001), and musculoskeletal system (p<.001) between groups. These results suggest that aging makes difference of function of these systems. In our view, counterplans need to be implemented, including exercise intervention to prevent decreases of fall risk,

마임 건강식품 홍삼진을 이용한 전통과 모던의 융합적 브랜드 이벤트 프로모션 산업체 연계를 통한 아트, 디자인, 공학, 마케팅 융합 디자인을 중심으로-

길혜경,박민지,이하은,조예린,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 융합 연출 디자인 이라는 목적에서 출발하여 마임 브랜드 홍삼진 제품을 다각적 측면에서 기획 및 분석하는데 목적이 있다. 이에 본 연구는 2017년 3월~ 6월 15주 동안 숙명여대 환경디자인학과<융합 캡스톤 디자인>수업을 통해 이루어졌다. 또한 본 연구는 마임브랜드 중, 건강식품을 브랜딩하고 있는 <홍삼 진>을 선택하였다. 그 결과 본 연구는 기존 이벤트 프로모션과 전시의 사회적 문제를 도출하였고, 이를 해결하기 위한 방안으로서 전통과 현대의 융합의 오감적 체험 프로모션을 주제로 선정하였다. 아울러 본 연구는 SWOT/STP 마케 팅 분석 방법과 브레인스토밍을 사용하여 아트, 디자인, ICT, Marketing의 융합 브랜드를 구축하였다.끝으로 본 연구는 향후 마케팅을 기반한 융합 브랜드 개발에 있어 기초 자료로 활용될 수 있을 것이라 기대된다.

여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석

김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.

Fault Current Limiting Characteristic of Non-inductively Wound HTS Magnets in Sub-cooled LN2 Cooling System

Dong Keun Park,Min Cheol Ahn,Seong Eun Yang,Chanjoo Lee,Bok-Ye01 Seek,Yong Soo Yoon,Tae Kuk Ko 한국초전도저온학회 (구 한국초전도저온공학회) 2006 한국초전도저온공학회논문지 Vol.8 No.2