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법음성학에서의 오디오 신호의 위변조 구간 자동 검출 방법 연구
양일호(Yang, IL-Ho),김경화(Kim, Kyung-Wha),김명재(Kim, Myung-Jae),백록선(Baek, Rock-Seon),허희수(Heo, Hee-Soo),유하진(Yu, Ha-Jin) 한국음성학회 2014 말소리와 음성과학 Vol.6 No.2
We propose a novel scheme for digital audio authentication of given audio files which are edited by inserting small audio segments from different environmental sources. The purpose of this research is to detect inserted sections from given audio files. We expect that the proposed method will assist human investigators by notifying suspected audio section which considered to be recorded or transmitted on different environments. GMM-UBM and GSV-SVM are applied for modeling the dominant environment of a given audio file. Four kinds of likelihood ratio based scores and SVM score are used to measure the likelihood for a dominant environment model. We also use an ensemble score which is a combination of the aforementioned five kinds of scores. In the experimental results, the proposed method shows the lowest average equal error rate when we use the ensemble score. Even when dominant environments were unknown, the proposed method gives a similar accuracy.
정상과 갑상선 종양조직에서 사람 IGF-I 유전자의 발현
홍성화,김진우,고석환,최영길,김영설,김광원,양인명,우정택,김성운,김덕윤,장현하,박상미 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.4
Many of the growth-promoting properties of growth hormone (GH) are mediated by insulin-like growth factor-I (KGF-I), a highly conserved circulation 70-amino ackd peptide. Recent studies have shown that multiple mechanisms influence IGF-I gene expression, including trascription from two pormoters, alternative RNA splicing and variable polyadenylation. In thyroid tissue, thyroid stimulating hormone (TSH) and TGF-I are the most possible candidates for follicular cell proliferation and hypertrophy. Actually IGF-I had autocrine and paracrine effect for tissue growing. We prepared thyroid tumor tissue mRNAs using single step method for detecting IGF-I levels according to different tissue, I, e, thyroid adenoma or papillary thyroid carcinoma. We used Northern blot analysis for IGF-I mRNA and Rnase protection assay (RPA) for IGF-I transcription start sites. For Northern blot, we used whole human IGF-I cDNA as a DNA probe and for RPA, we used IGF-I exon 1 containing noncoding promoter 1 as a riboprobe. We got good RNA bands from Northern blot analysis around 1 kb(IGF-I A) and 7.5 kb(IGF-I B) region. To clarify the amount of both IGF-IA and IB mRNAs, we measured autoradinographied signal of IGF-a mRNA's bands using densitometer. In IGF-IA signals, there's no change among liver and thyroid tissues, but in case of IGF-IB mRNA bands, thd signal was markedly increased in thyroid carcinoma tissues than that of normal thyroid tissue (85% vs 14%). In the study of RPA, aoo thyroid tissues used the same transcription start sites as those of liver's. We concluded that that this different regulation of IGF-I mRNA was originated from tissue specificity. That meant some tissue specific transcription factors were related to tissue IGF-I -Sung Woon Kim, et al. : Human IGF-I Gene Expression in Normal and Thyroid Tumor Tissues- expression (J Kor Soc Endocrinol 8: 414~421, 1993).
Sun Hye Kim,Ha Ney Choi,Ji-Yun Hwang,Namsoo Chang,Wha Young Kim,Hye Won Chung,Yoon Jung Yang 한국영양학회 2011 Nutrition Research and Practice Vol.5 No.3
The objectives of this study were to develop a food-frequency questionnaire (FFQ) for Vietnamese female immigrants in Korea and to evaluate the validity of the FFQ. A total of 80 food items were selected in developing the FFQ according to consumption frequency, the contribution of energy and other nutrients, and the cooking methods based on one-day 24 hour recall (24HR) from 918 Vietnamese female immigrants between November 2006 and November 2007. The FFQ was validated by comparison with 24HR of 425 Vietnamese female immigrants between November 2008 and August 2009. The absolute nutrient intake calculated from the FFQ was higher than that estimated by 24HR for most nutrients. The correlation coefficients between 24HR and FFQ ranged from 0.10 (vitamin C) - 0.36 (energy) for crude intake, 0.05 (vitamin E) - 0.32 (calcium) for per 1000 kcal, and 0.08 (zinc) - 0.34 (calcium) for energy-adjusted, respectively. More than 70% of subjects were classified into the same or adjacent agreement groups for nutrients other than fiber, sodium, vitamin A, vitamin C, and vitamin E, while less than 10% of subjects were classified into complete disagreement groups. We conclude that the FFQ appears to be an acceptable tool for estimating nutrient intake and dietary patterns of Vietnamese female immigrants in Korea. Future studies to validate the FFQ using various biomarkers or other dietary assessment methods are needed.