충수염의 임상적 고찰과 초음파의 유용성

박정배,양혁준,김형수,황성연,박철완,이근 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Appendicitis is the most common acute abdomen in Emergency Medical Center & outpatient department. But sometimes, it is difficult for us to diagnose because of clinically variable symptoms. We reviewed the ultrasonographic findings and analyse 521 cases of appendectomy patients about its distribution of sex and age, seasonal prevalence, clinical symptom and signs, laboratory findings, duration from onset of symptom to arrival at hospital, duration from arrival at hospital to operation, vital signs, operative results, and associated diseases, which were treated at the department of General Surgery & Emergency Medical Center in Chung Ang Gil Hospital from July, 1994 to June, 1995. The results were as follows : 1. The most common age group was second decade. And male to female ratio was 1.43:1. Seasonal variation was not significant. 2. Of 521 cases, 141 cases(27.1%) visited the hospital within 24 hours from the onset of symptom, and 259 cases(49.7%) visited between 24 to 48 hours. 3. In duration from arrival to operation, the cases within 6 hours were 263 (50.5%), the cases between 6 and 12 hours were 131(25..1%). 4. In systolic blood pressure, cases below 90mmHg were 19(3.6%), cases above 160mmHg were 23(4.4%). Below 60mmHg diastolic pressure were 55 cases(10.6%), cases above 110mmHg were 9(1.7%). In pulse rate, above 90 rate/min were 171(32.8%). 5. On admission leukocytosis was found in 413 cases(79.3%) and 342 cases of them were pathologic appendicitis. 6. Ultrasoundgraphy was performed in the 87 cases, but 23 cases were suggested appendicitis. Among 23 cases, 22(95.7%) revealed pathologic appendicitis at ooperation and labortatory examination. Of the 64 cases which were normal on ultrasonography, only 2 cases(3.1%) were proved to be appendicitis. 7. The results of 496 operations without ultrasonography were appendicitis in 390 cases(78.6%), mesenteric lymphadenopathy 36(7.3%), pelvic inflammatory disease 28(5.6%), fecalith 15(3.0%), terminal ileitis 8(1.6%), diverticulitis 7(1.4%), urinary tract stones 5(1.0%), cecal cancer 2 cases, right ovarian tumor 2 cases, tubo-ovarian abscess 2 cases, grater omentum internal hernia 1 case. Our results showed that the sensitivity of ultrasonohraphy was 95.8% and the specificity 98.4% in the diagnosis of appendicitis, It suggests that the ultrasonography is very helpful in the diagnosis & differential diagnosis of acute appeendiditis.

Cone Beam CT를 이용한 하악 제 1대구치 맹출 양상에 관한 연구

신정근,김재곤,백병주,양연미,정진우 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

건강한 정상 교합 어린이 83명(남자 42명, 여자 41명)을 대상으로 보호자 동의하에 cone beam CT 영상을 촬영하여, 하악 제1대구치의 맹출 양상을 연구하였다. 대상을 발육 정도에 따라 Nolla stage(4-10단계)로 구분한 후 삼차원 기준 평면인 전두면(frontal), 시상면(Sagittal), 수평면(horizontal)에서 각각 하악 제1대구치의 맹출 양상을 관찰하였다. 1. 전두면과 수평면에서, 하악 제1대구치간 폭경은 감소하였는데, stage 5에서 stage 8까지 가장 크게 감소했다가 약간 증가하였다. 2. 시상면과 전두면에서, 하악 제1대구치 맹출량은 교합평면을 기준으로 stage 5에서 stage 7까지 가장 많은 맹출 이동을 보였다. 3. 수평면과 시상면에서, 하악 제1대구치는 제2유구치 원심면으로부터 stage 4에서 stage 6까지 원심으로 이동하였고 이후 큰 변화가 없었다. 4. 시상면에서, 교합 평면과 하악 제1대구치의 근원심 치축이 이루는 각은 stage 4에서 stage 8까지 증가하였다. 5. 전두면에서, 교합 평면과 하악 제1대구치의 협설측 치축이 이루는 각은 지속적으로 증가하였다. 6. 수평면에서, 정중 시상면과 하악 제1대구치의 치축이 이루는 각은 stage 5부터 stage 8까지 증가하다 stage 8이후에는 다시 약간 감소하였다. The purpose of this study was to investigate the eruption pattern of the mandibular first molar in sagittal. frontal and horizontal views using the cone beam CT scanning. CT images were obtained from healthy 83 children(42 boys. 41 girls) between 3 to 10 years of age with a normal dentition according to Nolla stage. 1. In the frontal and horizontal view. the intermolar width decreased continuously with stage and slightly increased at the last stage. 2. In the sagittal and frontal view. eruption distances from occlusal plane were observed the largest change between stage 5 and 7. 3. In the horizontal and sagittal view. mandibular first molar from distal surface of primary second molar moved distally between stage 4 and 6. 4. In the sagittal view, angle from occlusal plane to mesio-distal axis increased between stage 4 and 8. 5. In the frontal view, angle from occlusal plane to bucco-lingual axis increased continuously during all stage. 6. In the horizontal view, angle from midsagittal plane to long axis increased between stage 5 and 8.

스티렌 폭로 근로자들의 기중 및 혈중 스티렌과 요중 만델산의 관계 분석

정호근,강성규,양정선,김기웅,이종성,조영숙,박인정 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

The concentration of styrene in air in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a polythylene bottle and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic acid were 8.16 ppm(geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory. Styrene in blood showed large difference by the working process. Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890 g/g creatinine and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption.

5년간 특수건강진단기관 분석정도관리 결과 분석

강성규,양정선,이미영,박인정,정호근 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목 적 : 1980년대 후반부터 산업보건에서 혈중 및 요중 중금속농도 분석의 정확성 문제가 크게 부각되었다. 같은 시료를 가지고 분석기관마다 보이는 커다란 오차로 인해 직업병 진단 결과에 대한 신뢰성을 크게 감소시켰다. 이에, 노동부에서는 1992년부터 특수건강진단 기관에 대한 생체시료 분석정도관리 프로그램을 시작하였다. 본 연구는 1995년부터 시작된 생체시료 분석정도관리 5년간의 결과를 보고하고, 현재 생물학적모니터링으로 사용되는 항목과 빈도를 조사하고 이 항목의 정도관리 참여율을 비교하여 산업보건 관계 연구나 직업병 관리에 참고할 수 있도록 하기 위해 실시하였다. 방 법 : 생체시료 분석정도관리는 무기와 유기분석분야로 나누어 일년에 전후반기 2회 실시하고 있으며, 지정항목과 자율항목으로 구분하고 있다. 지정항목인 혈중 납과 요중 마뇨산은 분야별로 한 번에 3개 농도수준을 주어 2개 이상이 기준값의 ±15%내외의 범위에 들면 적합한 것으로 판정하고 있으며, 자율항목은 2개의 시료를 주어 2개 모두 기준실험실 평균값의 ±3SD 내외의 범위에 들면 적합한 것으로 판정하고 있다. 결 과 : 지정항목인 혈중 납과 요중 마뇨산 분석은 평균 적합률이 각각 89%, 90% 이었고, 대학기관, 비영리법인, 종합병원, 사업장 자체기관별로 차이는 없었으나 신규 기판의 적합률 70% 수준으로 상대적으로 낮았다. 자율항목의 적합률은 평균 50% 수준이었고, 저농도보다는 고농도의 적합률이 떨어졌다. 국내에서 가장 많이 분석되고 있는 항목은 요중 마뇨산과 혈중 납이었고, 혈중 및 요중 망간도 많이 분석되고 있었다. 요중 삼염화물, 페놀, 만델산, 카드윰, 메칠마뇨산, 크롬 등도 많이 분석되고 있는 항목이었다. 혈중 망간, 요중 수은, 요중 NMF는 정도관리에서 적합판정을 받은 기관의 숫자보다 실제 분석을 하고 있는 기관의 숫자가 많았다. 결 론 : 지난 5년간의 생체시료 분석정도관리 결과 우리나라 분석실험실의 분석능력은 향상되고 있으나, 자율항목에 대한 분석능력은 아직 미흡한 것으로 나타났다. 그리고, 아직 일부 일부 항목에 대해서는 외부 정도관리 없이 분석되고 있는 경우도 있었다. Objective : The accuracy of analytical results of blood and urine heavy metals came out to the main issue on occupational health from late eighties. The discrepancy of the results for same samples from different laboratories made the diagnosis for occupational diseases be unreliable. Therefore, a quality control program for analysis of samples taken from workplace had been introduced in Korea since 1992. This study aims to show the quality control program for analysis of blood and urine samples and its proficient rates from 1992 to 1999 and to know how they have been being used in occupational health. Methods The quality control program runs twice a year with mandatory items of blood lead and urine hippuric acid and voluntary items of blood cadmium and manganese and urine mandellic acid and methyl hippuric acid. Participant laboratories are receiving three levels for each items and two out of three samples have to be qualified for being a profi-cient laboratory for the item. The acceptable range of blood lead and urine hippuric acid is ± 15% and that of the others is within 3 SD (standard deviation) from the reference values. Results : The proficient rates of blood lead and urine hippuric acid was 89%, 90%, repectively, however those of the other voluntary items have been from 51% to 62%. The proficient rates of urine mercury and urine N-methylformamide (NMF), which are introduced since 1999, were very poor. Urine hippuric acid and blood lead were analyzed frequently for the purpose of biological monitoring conducting by special health examination organizations. Urine and blood manganese and urine metabolites of trichloroethylene, urine phenol, methylhippuric acid and cadmium were followed. Conclusions : In conclusion, the quality control program for biological monitoring has dramatically improve the ability of analysing blood and urine samples and eventually con-tributes to diagnose occupational diseases and to prevent occupational poisoning. However, some biological monitoring data, such as urine manganese, mercury and NMF, have been still reported from laboratories that were not accepted as a proficient laboratory.

펠렛형 제올라이트를 이용한 이산화황의 흡착특성

이재희,김정국,양희철,김준형,이제근 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.1

KA, NaA, CaA 및 NaX 제올라이트가 충전된 실험실 규모의 흡착층을 이용하여 SO_2 유입농도, 충전층 높이 및 공간속도를 변화시키면서 SO_2 흡착실험을 수행하였다. 평형흡착량과 파과시간 모두 제올라이트 세공크기에 따라 KA, NaA, CaA, NaX 순으로 증가하였다. NaX상에서 SO_2를 흡착시킬 경우 SO_2 유입농도 504ppm 이하에서 파과시간은 증가하나 역시 물질전달범위도 증가하여 물질전달 속도는 감소하였다. Wheeler 식으로부터 제올라이트상의 파과시간에 대한 평형흡착량, 공간속도 및 1/C_0의 관계를 확인한 결과, 504ppm 이상보다 504ppm 이하의 저농도에서 파과시간이 상대적으로 증가하였다. The experimental of SO_2 adsorption, with varying SO_2 concentration, packed-bed depth, and space velocity, was carried out using a lab-scale fixed bed with zeolites, such as KA, NaA, CaA and NaX. Both of an equilibrium adsorption capacity and a breakthrough time increased with zeolite pore size, in order of KA, NaA, CaA and NaX. Breakthrough time of NaX increased under SO_2 concentration of 504 ppm, but mass transfer rate decreased due to expansion of mass transfer zone. Breakthrough time is relatively increased in the low gas concentration(<504 ppm) more than high concentration(>504 ppm), which is proved by the effects of equilibrium adsorption capacity, space velocity and l/C_0 for the zeolite from the relationship of Wheeler equation.

유방암종에서 p53, cyclin D1 및 cathersin D 단백발현의 의의

문경래,김환정,이미자,기근홍,서재홍,양정원,조현진 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives: Breast carcinoma is a heterogenous disease. The prognosis of this carcinoma correlates with various prognostic factors. The aim of this study was to assess the prognostic significance of expression of p53, cyclin Dl and cathepsin D protiens in association with various prognostic factors in invasive breast carcinoma. Materials and Methods: The relationship is presented between expression of p53, cyclin D1 and cathepsin D by immunohistochemistry and various established prognostic factors such as tumor size, histologic grade, lymph node status and extensive intraductal component in 55 cases of invasive breast carcinoma. Results: No significant correlations were observed between expression of p53, cyclin Dl and cathepsin D and tumor size. The expression of p53 correlated with high histologic grade. The expression of p53 and cyclin Dl correlated with lymph node metastasis. Conclusion: These results indicate that expression of p53 and cyclin Dl in invasive ductal carcinoma may be an important prognostic factor, closely related to the high histologic grade and lymph node metastasis.

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

A Precise Position Control of Robot Manipulator with Eight Joints

Yang-Keun Jeong,Seung-Hack Baek,Jong Bum Won,Jeong-Man Park,Hyun-Cheol Lee,Sung-Hyun Han 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10

Self-Transcendence Mediates the Relationship between Early Trauma and Fatal Methods of Suicide Attempts

Yang Jeong Hun,Rhee Sang Jin,Park C. Hyung Keun,Kim Min Ji,Shin Daun,Lee Jae Won,Kim Junghyun,Kim Hyeyoung,Lee Hyun Jeong,Ha Kyooseob,Ahn Yong Min 대한의학회 2021 Journal of Korean medical science Vol.36 No.5

Background: Early trauma is known to be a risk factor of suicide-related behavior. On the other hand, people who attempt suicide using a fatal method are reported to be more likely to complete suicide. In this study, we assumed that early trauma affects an individual's temperament and character and thereby increases the risk of a fatal method of suicide attempts. Methods: We analyzed 92 people with a history of previous suicide attempts. We compared the Temperament and Character Inventory-Revised scores between the groups with and without early trauma, and between the groups with and without a history of suicide attempt using fatal methods through an analysis of covariance with age, sex, and presence of a psychiatric history as covariates. A mediation analysis was conducted of the relationship between early trauma and fatal methods of suicide attempt with self-transcendence as a mediator. Results: Higher self-transcendence was reported in the fatal group (27.71 ± 13.78 vs. 20.97 ± 12.27, P = 0.010) and the early trauma group (28.05 ± 14.30 vs. 19.43 ± 10.73, P = 0.001), respectively. The mediation model showed that self-transcendence mediates the relationship between early trauma and fatal methods of suicide attempt. The 95% confidence intervals for the direct and indirect effect were (−0.559, 1.390) and (0.026, 0.947), respectively. Conclusion: Self-transcendence may mediate the relationship between early trauma and fatal methods of suicide attempt. Self-transcendence may be associated with unhealthy defenses and suicidal behavior for self-punishment and may constitute a marker of higher suicide risk.

밸런스워킹PT의 지도자와 학습자의 가치정향 분석

정양근(Jeong, Yang-Keun),유정애(You, Jeong-Ae) 한국코칭능력개발원 2021 코칭능력개발지 Vol.23 No.3