A compact fourth-order finite difference scheme for the three-dimensional Cahn-Hilliard equation

Li, Y.,Lee, H.G.,Xia, B.,Kim, J. North-Holland Pub. Co 2016 Computer physics communications Vol.200 No.-

<P>This work extends the previous two-dimensional compact scheme for the Cahn-Hilliard equation (Lee et al., 2014) to three-dimensional space. The proposed scheme, derived by combining a compact formula and a linearly stabilized splitting scheme, has second-order accuracy in time and fourth-order accuracy in space. The discrete system is conservative and practically stable. We also implement the compact scheme in a three-dimensional adaptive mesh refinement framework. The resulting system of discrete equations is solved by using a multigrid. We demonstrate the performance of our proposed algorithm by several numerical experiments. (C) 2015 Elsevier B.V. All rights reserved.</P>

Sauchinone from Saururus chinensis protects vascular inflammation by heme oxygenase-1 induction in human umbilical vein endothelial cells

Li, B.,Lee, Y.J.,Kim, Y.C.,Yoon, J.J.,Lee, S.M.,Lee, Y.P.,Kang, D.G.,Lee, H.S. G. Fischer 2014 Phytomedicine Vol.21 No.2

Sauchinone, a diastereomeric lignan isolated from the roots of Saururus chinensis (LOUR.) BAILL. (Saururaceae), is reported to exert a variety of biological activities such as hepatoprotective, anti-inflammatory actions and inhibitory effects on bone resorption. In this study, we investigated the effect of sauchinone in suppressing cell adhesion molecules such as vascular cell adhesion molecule-1 (VCAM-1) and intracellular adhesion molecule-1 (ICAM-1) expression in high glucose stimulated human umbilical vein endothelial cells (HUVEC). Sauchinone inhibited the phosphorylation and degradation of IκB-α, as well as the nuclear translocation of nuclear factor kappa B (NF-κB) p65 caused by the stimulation of high glucose. In addition, sauchinone induced heme oxygenase (HO)-1 expression through nuclear translocation of nuclear factor E2-related factor 2 in HUVEC. The effects of sauchinone on the high glucose-induced expression of VCAM-1 and ICAM-1 and nuclear translocation of NF-κB p65 were partially reversed by transfection of the cells with HO-1 siRNA. These findings suggest that sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of sauchinone in HUVEC.

Enhanced strength and ductility in particulate-reinforced aluminum matrix composites fabricated by flake powder metallurgy

Kai, X.Z.,Li, Z.Q.,Fan, G.L.,Guo, Q.,Xiong, D.B.,Zhang, W.L.,Su, Y.S.,Lu, W.J.,Moon, W.J.,Zhang, D. Elsevier Sequoia 2013 Materials science & engineering. properties, micro Vol.587 No.-

Reinforcement agglomeration always leads to severe stress concentration and porosity, which is detrimental to the deformation ability and mechanical properties of particulate-reinforced metal matrix composites. In this study, uniform distribution of 32vol%B<SUB>4</SUB>C has been achieved in B<SUB>4</SUB>C/Al composite by means of flake powder metallurgy (Flake PM), in which flake Al powder is used as the starting material. The flake Al powder exhibits higher apparent volume than spherical powders of the same mass, and thus can provide more space to accommodate the B<SUB>4</SUB>C particles. Therefore, compared with conventional PM, Flake PM can lead to more uniform distribution of B<SUB>4</SUB>C particles in the composite powder as well as in the consolidated composite. Meanwhile, the flake Al powder has a nano skin of Al<SUB>2</SUB>O<SUB>3</SUB>, which could be fractured and dispersed inside the fine matrix grains during consolidation, and were found to induce a higher normalized strain hardening rate for the composite during deformation. As a result, the Flake PM 32vol%B<SUB>4</SUB>C/Al composite exhibits an ultimate tensile strength of 305MPa and a uniform elongation of 6.6%, 63% stronger and 13% more ductile than its counterpart fabricated by conventional PM.

Comparison of Motility, Acrosome, Viability and ATP of Boar Sperm with or without Cold Shock Resistance in Liquid Semen at 17℃ and 4℃, and Frozen-thawed Semen

Yi, Y.J.,Li, Z.H.,Kim, E.S.,Song, E.S.,Kim, H.B.,Cong, P.Q.,Lee, J.M.,Park, Chang-Sik Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.2

This study was designed to analyze boar sperm to compare motility, acrosome morphology, viability and ATP by various preservation methods between Duroc boar A with cold shock resistance sperm and Duroc boar B with cold shock sensitivity sperm. Semen volume, sperm concentration, motility and normal acrosome between Duroc boar A and B did not show any differences within 2 h after collection. There were no differences in sperm motility and normal acrosome between boar A and B at 1 day of preservation at $17^{\circ}C$ and $4^{\circ}C$, respectively. However, sperm motility and normal acrosome from 2 day of preservation at $17^{\circ}C$ and $4^{\circ}C$, respectively, were higher for boar A than boar B. The frozen-thawed sperm motility and normal acrosome were higher for boar A than boar B. The sperm viability and ATP concentration according to storage period of liquid semen at $17^{\circ}C$ and $4^{\circ}C$ were higher for boar A than boar B. Also, the sperm viability and ATP concentration of frozen-thawed semen were higher for boar A than boar B. In conclusion, we found out that the original quality of boar semen with cold shock resistance sperm played an important role.

A fractional approach to the time-temperature dependence of dynamic viscoelastic behavior

Z. L. Li,Y. Qin,B. Sun,C. L. Jia,W. J. Zhang,B. J. Yan,Q. L. Shi 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.1

Fractional derivative and WLF equation are effective in describing the dynamic behavior and time-temperature effect of viscoelastic damping materials, respectively. These approaches have essentially evolved from the viscoelastic constitutive behavior. Based on such intrinsic relation, a fractional time-temperature superposition principle model (FTTSPM) that integrates the fractional constitutive relation and WLF equation was proposed. The parameters of this model were determined by performing tensile and DMA tests, and the master curves at 5 °C constructed by FTTSPM and WLF equation were compared. The theoretical prediction over the extended frequency span as the master curves was made by using the fractional standard linear solid model (FSLSM) to validate FTTSPM. The numerical results show that FTTSPM conforms to the time-temperature superposition principle. The parameters α and B¢ in this model denote the impact of the material and environment on the shifted factor, respectively. For the storage and loss modulus, the extended frequency obtained by FTTSPM is broader than that obtained by the WLF equation. Moreover, the evaluation of the storage and loss modulus by FTTSPM is much closer to the theoretical prediction compared with that by the WLF equation. Therefore, FTTSPM is a concise and experiment-based approach with a higher precision and greater frequency-extended capacity compared with the WLF equation. However, FTTSPM inevitably faces a vertical shift when non-thermo-rheologically simple materials are considered. The physical mechanism and practical application of FTTSPM will be examined in further research.

Novel measurement method of heat and light detection for neutrinoless double beta decay

Kim, G.B.,Choi, J.H.,Jo, H.S.,Kang, C.S.,Kim, H.L.,Kim, I.,Kim, S.R.,Kim, Y.H.,Lee, C.,Lee, H.J.,Lee, M.K.,Li, J.,Oh, S.Y.,So, J.H. North-Holland 2017 Astroparticle physics Vol.91 No.-

<P>We developed a cryogenic phonon-scintillation detector to search for O nu beta beta decay of Mo-100. The detector module, a proto-type setup of the AMoRE experiment, has a scintillating (CaMoO4)-Ca-40-Mo-100 absorber composed of Mo-100-enriched and Ca-48-depleted elements. This new detection method employs metallic magnetic calorimeters (MMCs) as the sensor technology for simultaneous detection of heat and light signals. It is designed to have high energy and timing resolutions to increase sensitivity to probe the rare event. The detector, which is composed of a 200 g (CaMoO4)-Ca-40-Mo-100 crystal and phonon/photon sensors, showed an energy resolution of 8.7 keV FWHM at 2.6 MeV, with a weak temperature dependence in the range of 10-40 mK. Using rise-time and mean-time parameters and light/heat ratios, the proposed method showed a strong capability of rejecting alpha-induced events from electron events with as good as 20 sigma separation. Moreover, we discussed how the signal rise-time improves the rejection efficiency for random coincidence signals. (C) 2017 The Author(s). Published by Elsevier B.V.</P>

Influence of geology and human activity on the genetic structure and demography of the Oriental fire-bellied toad (Bombina orientalis)

Fong, J.J.,Li, P.P.,Yang, B.T.,Zhou, Z.Y.,Leache, A.D.,Min, M.S.,Waldman, B. Academic Press 2016 Molecular phylogenetics and evolution Vol.97 No.-

The Oriental fire-bellied toad (Bombina orientalis) is a commonly used study organism, but knowledge of its evolutionary history is incomplete. We analyze sequence data from four genetic markers (mtDNA genes encoding cytochrome c oxidase subunit I, cytochrome b, and 12S-16S rRNA; nuDNA gene encoding recombination activating gene 2) from 188 individuals across its range in Northeast Asia to elucidate phylogeographic patterns and to identify the historic events that shaped its evolutionary history. Although morphologically similar across its range, B. orientalis exhibits phylogeographic structure, which we infer was shaped by geologic, climatic, and anthropogenic events. Phylogenetic and divergence-dating analyses recover four genetically distinct groups of B. orientalis: Lineage 1-Shandong Province and Beijing (China); Lineage 2-Bukhan Mountain (Korea); Lineage 3-Russia, Northeast China, and northern South Korea; and Lineage 4-South Korea. Lineage 2 was previously unknown. Additionally, we discover an area of secondary contact on the Korean Peninsula, and infer a single dispersal event as the origin of the insular Jeju population. Skyline plots estimate different population histories for the four lineages: Lineages 1 and 2 experienced population decreases, Lineage 3 remained stable, while Lineage 4 experienced a sharp increase during the Holocene. The timing of the population expansion of Lineage 4 coincides with the advent of rice cultivation, which may have facilitated the increase in population size by providing additional breeding habitat.

Investigation of PCR-RFLPs within Major Histocompatibility Complex B-G Genes Using Two Restriction Enzymes in Eight Breeds of Chinese Indigenous Chickens

R. F. Xu,K. Li,G. H. Chen,B. Y. Z. Qiang,D. L. Mo,B. Fan,C. C. Li,M. Yu,M. J. Zhu,T. A. Xiong,B. Liu 아세아·태평양축산학회 2005 Animal Bioscience Vol.18 No.7

New polymorphism of major histocompatibility complex B-G genes was investigated by amplification and digestion of a 401bp fragment including intron 1 and exon 2 using polymerase chain reaction-restriction fragment length polymorphism (PCRRFLP) technique with two restriction enzymes of Msp I and Tas I in eight breeds of Chinese indigenous chickens and one exotic breed. In the fragment region of the gene, three novel single nucleotide polymorphisms (SNPs) were detected at the two restriction sites. We found the transition of two nucleotides of A294G and T295C occurred at Tas I restriction site, and consequently led to a nonsynonymous substitution of asparagine into serine at position 54 within the deduced amino acid sequence of immunoglobulin variableregion- like domain encoded by the exon 2 of B-G gene. It was observed at rare frequency that a single mutation of A294G occurring at the site, also caused an identical substitution of amino acid, asparagine 54-to-serine, to that we described previously. And the transversion of G319C at Msp I site led to a non-synonymous substitution, glutamine 62-to-histidine. The new alleles and allele frequencies identified by the PCR-RFLP method with the two enzymes were characterized, of which the allele A and B frequencies at Msp I and Tas I loci were given disequilibrium distribution either in the eight Chinese local breeds or in the exotic breed. By comparison, allele A at Msp I locus tended to be dominant, while, the allele B at Tas I locus tended to be dominant in all of the breeds analyzed. In Tibetan chickens, the preliminary association analysis revealed that no significant difference was observed between the different genotypes identified at the Msp I and Tas I loci and the laying performance traits, respectively.

Inter - Grain Exchange Interaction and Hysteresis Loops of Melt - Spun Nd₁₃Fe77B10

J. H. Min,Y. B. Kim,W. S. Park,M. J. Park,Li Tian 한국자기학회 1996 Journal of Magnetics Vol.1 No.2

Hysteresis loops of melt-spun Nd₁₃Fe_(77) B_(10) cooled down at remanent state were measured at 4.2 K and 250 K. The hysteresis loops were analysed on the basis of the Stoner-Wohlfarth (S-W) model, the inter-grain exchange coupled single domain (SD) model and micromagnetism. The coercivity higher than that predicted from the S-W model and the striking shift of the thin minor loop along the H-axis observed at the fields of Hmax = 4 MA/m at 4.2 K indicated new evidences for the inter-grain exchange interaction. The S-W model failed in explaining the high_i Hc and the shift of the thin minor loop. The exchange coupled SD model was found to explain the experimental results qualitatively without difficulties associated with the S-W model. The micromagnetic calculations using a finite element technique simulated the experimental results fairly well quntitatively.

중년 사무직 남성의 직무스트레스와 허리둘레, 체질량지수의 관계에 관한 연구

강수임,고보경,김지영,노정연,리청,송주은,이현영,이혜민,최유경,정덕유,이민경 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: The purpose of this study was to determine the relationship between job stress, body mass index and waist circumference among middle aged male workers. Methods: Using a descriptive correlation study design, a total of 122 middle aged male workers were recruited through convenience sampling from November 8 to December 13, 2015. The questionnaire included in this study were general characteristics and the Korean Occupational Stress Scale-Short Form (KOSS-SF). Data were statistically analyzed using SPSS windows version 22 program with Pearson’s correlation coefficient. Results: A significant relationship was found between job stress, body mass index (p=.043) and waist circumference (p=.007). Conclusion: These results suggest that high job stress are significantly associated with both body mass index and waist circumference of middle aged male workers. This implies a need for intervention that focuses on reducing obesity and metabolic syndrome influenced by job stress.