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Jin, Xuan-Ji,Lee, Eun-Jeong,Choi, Jae-Eul The Korean Society of Crop Science 2007 Journal of crop science and biotechnology Vol.10 No.1
Classification of blast resistance type of 129 Korean rice cultivars was carried out based on reaction pattern to 10 Japanese blast pathogen isolates(Pyricularia oryzae). The cultivars were divided into 11 groups based on the presumed resistance genes as follows; Pia type(19 cultivars), Pita-2 type(4), Pik type(3), Pib type(5), Piz type(11), Pik-s type(8), Pik and Pii type(4), Pia and Pita type(8), Pia and Pik type(6), Pita, Pik and Pii type(4) and no-grouping type(57). These results would provide important information to rice breeding for durable and broad resistance to rice blast.
Nicotine exacerbates tacrolimus-induced renal injury by programmed cell death
( Yu Ji Jiang ),( Sheng Cui ),( Kang Luo ),( Jun Ding ),( Qi Yan Nan ),( Shang Guo Piao ),( Mei Ying Xuan ),( Hai Lan Zheng ),( Yong Jie Jin ),( Ji Zhe Jin ),( Jung Pyo Lee ),( Byung Ha Chung ),( Bum 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.6
Background/Aims: Cigarette smoking is an important modifiable risk factor in kidney disease progression. However, the underlying mechanisms for this are lacking. This study aimed to assess whether nicotine (NIC), a major toxic component of cigarette smoking, would exacerbates tacrolimus (TAC)-induced renal in-jury. Methods: Sprague-Dawley rats were treated daily with NIC, TAC, or both drugs for 4 weeks. The influence of NIC on TAC-caused renal injury was examined via renal function, histopathology, oxidative stress, mitochondria, endoplasmic reticulum (ER) stress, and programmed cell death (apoptosis and autophagy). Results: Both NIC and TAC significantly impaired renal function and histopathology, while combined NIC and TAC treatment aggravated these parameters beyond the effects of either alone. Increased oxidative stress, ER stress, mitochondrial dysfunction, proinflammatory and profibrotic cytokine expressions, and programmed cell death from either NIC or TAC were also aggravated by the two combined. Conclusions: Our observations suggest that NIC exacerbates chronic TAC nephrotoxicity, implying that smoking cessation may be beneficial for transplant smokers taking TAC.
( Hai Yan Zhao ),( Hui Ying Li ),( Jian Jin ),( Ji Zhe Jin ),( Long Ye Zhang ),( Mei Ying Xuan ),( Xue Mei Jin ),( Yu Ji Jiang ),( Hai Lan Zheng ),( Ying Shun Jin ),( Yong Jie Jin ),( Bum Soon Choi ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.0
Background/Aims: Accumulating evidence indicates that L-carnitine (LC) protects against multiorgan damage through its antioxidant properties and preservation of the mitochondria. Little information is available about the effects of LC on renal fibrosis. This study examined whether LC treatment would provide renoprotection in a rat model of unilateral ureteral obstruction (UUO) and in vitro. Methods: Sprague-Dawley rats that underwent UUO were treated daily with LC for 7 or 14 days. The influence of LC on renal injury caused by UUO was evaluated by histopathology, and analysis of gene expression, oxidative stress, mitochondrial function, programmed cell death, and phosphatidylinositol 3-kinase (PI3K)/ AKT/forkhead box protein O 1a (FoxO1a) signaling. In addition, H<sub>2</sub>O<sub>2</sub>-exposed human kidney cells (HK-2) were treated with LC. Results: LC treatment inhibited expression of proinflammatory and profibrotic cytokines, and was followed by a significant attenuation of tubulointerstitial inflammation and fibrosis. The increased oxidative stress caused by UUO was associated with mitochondrial dysfunction and excessive apoptosis and autophagy via PI3K/AKT/FoxO1a-dependent signaling, and this was abrogated by administration of LC. In H<sub>2</sub>O<sub>2</sub>-exposed HK-2 cells, LC decreased intracellular production of reactive oxygen species, and suppressed expression of profibrotic cytokines and reduced the number of apoptotic cells. Conclusions: LC protects against the progression of tubulointerstitial fibrosis in an obstructed kidney.
( Ji Hoon Ha ),( A Rang Kim ),( Keon-soo Lee ),( Song Hua Xuan ),( Hee Cheol Kang ),( Dong Hwan Lee ),( Mi Yeon Cha ),( Hye Jin Kim ),( Mi An ),( Soo Nam Park ) 한국미생물 · 생명공학회 2019 Journal of microbiology and biotechnology Vol.29 No.1
The effects of Lavandula angustifolia extract fermented with Pediococcus pentosaceus DK1 on UVB-mediated MMP-1 expression and collagen decrease in human skin fibroblasts were determined, and the conversion of its components was also analyzed. Fermentation was performed at varying L. angustifolia extract and MRS medium concentrations, and optimal fermentation conditions were selected. L. angustifolia extracts showed decreased cytotoxicity after fermentation in the fibroblasts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extract showed MMP-1 expression 8.2-14.0% lower than that in UVB-irradiated fibroblasts treated with non-fermented extract. This was observed even at fermented extract concentrations lower than those of non-fermented extracts. Fibroblasts treated with fermented L. angustifolia extract showed 20% less reduction in collagen production upon UVB irradiation than those treated with non-fermented extracts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extracts showed 50% higher inhibition of ROS generation than those treated with non-fermented extract. Luteolin and apigenin glycosides of L. angustifolia were converted during fermentation, and identified using RP-HPLC and LC/ESI-MS. Therefore, the effects of L. angustifolia extract on MMP-1 expression and collagen decrease in UVB-irradiated human skin fibroblasts were increased through fermentation by P. pentosaceus.
Mechanical, electrical and wear properties of Cu-TiB2 nanocomposites fabricated by MA-SHS and SPS
Ji-Soon Kim,Dae-Hwan Kwon,Thuy Dang Nguyen,Khoa Xuan Huynh,Pyuck-Pa Choi,Myung-Gyu Chang,Young-Jin Yum,Young-Soon Kwon 한양대학교 세라믹연구소 2006 Journal of Ceramic Processing Research Vol.7 No.3
Cu-TiB2 nanocomposite powders were obtained by means of a combination of mechanical treatment and combustion reaction. Spark plasma sintering (SPS) was used to inhibit grain growth and thereby obtain fully dense Cu-TiB2 sintered bodies with a nanocomposite structure. The phases of the synthesized product were identified using X-ray diffraction and results showed only Cu and TiB2, with no other phases existing in the product. The particle size of self-propagating high-temperature synthesized powder was smaller than 250 nm. Mechanical and electrical properties were investigated after SPS at 650 oC for 30 minutes, the electrical conductivity decreased from 75 to 54% International Annealed Copper Standard (IACS) with the TiB2 content increased from 2.5 to 10 wt.%. while the hardness increased from 56 to 97 HRB. In addition, the tensile strength and wear resistance of the composites increased as the TiB2 content increased. Cu-TiB2 nanocomposite powders were obtained by means of a combination of mechanical treatment and combustion reaction. Spark plasma sintering (SPS) was used to inhibit grain growth and thereby obtain fully dense Cu-TiB2 sintered bodies with a nanocomposite structure. The phases of the synthesized product were identified using X-ray diffraction and results showed only Cu and TiB2, with no other phases existing in the product. The particle size of self-propagating high-temperature synthesized powder was smaller than 250 nm. Mechanical and electrical properties were investigated after SPS at 650 oC for 30 minutes, the electrical conductivity decreased from 75 to 54% International Annealed Copper Standard (IACS) with the TiB2 content increased from 2.5 to 10 wt.%. while the hardness increased from 56 to 97 HRB. In addition, the tensile strength and wear resistance of the composites increased as the TiB2 content increased.
Large-Scale Plasma Patterning of Transparent Graphene Electrode on Flexible Substrates
Kim, Ji Hye,Ko, Euna,Hwang, Joonki,Pham, Xuan-Hung,Lee, Joo Heon,Lee, Sung Hwan,Tran, Van-Khue,Kim, Jong-Ho,Park, Jin-Goo,Choo, Jaebum,Han, Kwi Nam,Seong, Gi Hun American Chemical Society 2015 Langmuir Vol.31 No.9
<P>Graphene, a two-dimensional carbon material, has attracted significant interest for applications in flexible electronics as an alternative transparent electrode to indium tin oxide. However, it still remains a challenge to develop a simple, reproducible, and controllable fabrication technique for producing homogeneous large-scale graphene films and creating uniform patterns with desired shapes at defined positions. Here, we present a simple route to scalable fabrication of flexible transparent graphene electrodes using an oxygen plasma etching technique in a capacitively coupled plasma (CCP) system. Ascorbic acid-assisted chemical reduction enables the large-scale production of graphene with solution-based processability. Oxygen plasma in the CCP system facilitates the reproducible patterning of graphene electrodes, which allows controllable feature sizes and shapes on flexible plastic substrates. The resulting graphene electrode exhibits a high conductivity of 80 S cm<SUP>–1</SUP> and a transparency of 76% and retains excellent flexibility upon hard bending at an angle of ±175° and after repeated bending cycles. A simple LED circuit integrated on the patterned graphene film demonstrates the feasibility of graphene electrodes for use in flexible transparent electrodes.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2015/langd5.2015.31.issue-9/la504443a/production/images/medium/la-2014-04443a_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/la504443a'>ACS Electronic Supporting Info</A></P>
정량적 피드백 이론을 이용한 유압 로드 시뮬레이터에 관한 힘 제어계 설계
김진완(Jin Wan Kim),현동길(Dong Ji Xuan),김영배(Young Bae Kim) 대한기계학회 2007 大韓機械學會論文集A Vol.31 No.11
This paper presents the road simulator control technology for reproducing the road input signal to implement the real road data. The simulator consists of the hydraulic pump, servo valve, hydraulic actuator and its control equipment. The QFT(Quantitative Feedback Theory) is utilized to control the simulator effectively. The control system illustrates a tracking performance of the closed-loop controller with low order transfer function G(s) and pre-filter F(s) for a parametric uncertain model. A force controller is designed to communicate the control signal between simulator and digital controller. Tracking specification is satisfied with upper and lower bound tolerances on the steep response of the system to the reference signal. The efficacy of the QFT force controller is verified through the numerical simulation, in which combined dynamics and actuation of the hydraulic servo system are tested. The simulation results show that the proposed control technique works well under uncertain hydraulic plant system. The conventional software (Labview) is used to make up for the real controller in the real-time basis, and the experimental works show that the proposed algorithm works well for a single road simulator.
3 축 유압 도로 시뮬레이터의 정량적 피드백 제어 시스템 설계
김진완(Jin Wan Kim),현동길(Dong Ji Xuan),김영배(Young Bae Kim) 대한기계학회 2008 大韓機械學會論文集A Vol.32 No.3
This paper presents design of the quantitative feedback control system of the three axes hydraulic road simulator with respect to the dummy wheel for uncertain multiple input-output(MIMO) feedback systems. This simulator has the uncertain parameters such as fluid compressibility, fluid leakage, electrical servo components and nonlinear mechanical connections. This works have reproduced the random input signal to implement the real road vibration's data in the lab. The replaced m2 MISO equivalent control systems satisfied the design specifications of the original m*m MIMO control system and developed the mathematical method using quantitative feedback theory based on schauder's fixed point theorem. This control system illustrates a tracking performance of the closed-loop controller with low order transfer function G(s) and pre-filter F(s) having the minimum bandwidth for parameters of uncertain plant. The efficacy of the designed controller is verified through the dynamic simulation with combined hydraulic model and Adams simulator model. The Matlab simulation results to connect with Adams simulator model show that the proposed control technique works well under uncertain hydraulic plant system. The designed control system has satisfied robust performance with stability bounds, tracking bounds and disturbance. The Hydraulic road simulator consists of the specimen, hydraulic pump, servo valve, hydraulic actuator and its control equipments
QFT를 이용한 유압 로드 시뮬레이터에 관한 힘 제어계 설계
김진완(Jin Wan Kim),현동길(Dong Ji Xuan),남양해(Yang Hai Nan),김영배(Young Bae Kim) 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.5
This paper presents the road simulator control technology for reproducing the road input signal to implement the real road data. The simulator consists of the hydraulic pump, servo valve, hydraulic actuator and its control equipment. The QFT is utilized to control the simulator effectively. The control system illustrates a tracking performance of the closed-loop controller with low order transfer function G(s) and pre-filter F(s) for a parametric uncertain model. A force controller is designed to communicate the control signal between simulator and digital controller. The efficacy of the QFT force controller is verified through the numerical simulation, in which combined dynamics and actuation of the hydraulic servo system are tested. The simulation results show that the proposed control technique works well under uncertain hydraulic plant system. The conventional software (Labview) is used to make up for the real controller in the real-time basis, and the experimental works show that the proposed algorithm works well for a single road simulator.