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Cembranoid Diterpenes from the Soft Coral Lobophytum crassum and Their Anti-inflammatory Activities
Cuong, Nguyen Xuan,Thao, Nguyen Phuong,Luyen, Bui Thi Thuy,Ngan, Nguyen Thi Thanh,Thuy, Dinh Thi Thu,Song, Seok Bean,Nam, Nguyen Hoai,Kiem, Phan Van,Kim, Young Ho,Minh, Chau Van Pharmaceutical Society of Japan 2014 Chemical & pharmaceutical bulletin Vol.62 No.2
The Impact of Corporate Social Responsibility on Brand Image: A Case Study in Vietnam
Cuong Xuan PHAN,Lam Van LE,Duy DUONG,Thuy Chung PHAN 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.4
This paper examines the impact of university social responsibility on brand image and student satisfaction. Social responsibility impact on consumer behavior has been studied extensively. But the same impact has not been rigorously tested to the same extend in the education sector. Firstly, we analyze the perception of university social responsibility (USR) and its components, including (1) the quality of teaching programs, facilities, and academic staff; (2) supporting learning activities; and (3) human resource policies. Secondly, we investigate the relationship between university social responsibility, brand image, and student satisfaction. The study examined these relationships through a proposed economic model based on answers from a survey of 298 students at the University of Food Industry Ho Chi Minh City. From the above survey data, the author proceeds to quantify variables and, based on Cronbach’s Alpha reliability coefficient, EFA factor analysis, and linear regression, to measure the impact of each social responsibility factor on business of the university and student satisfaction. The results show that university social responsibility actually affects the university’s brand image and student satisfaction. Our findings suggest that universities should develop an appropriate marketing strategy to reinforce brand image and student satisfaction through the university social responsibility model.
Cuong, Nguyen Xuan,Thao, Nguyen Phuong,Luyen, Bui Thi Thuy,Ngan, Nguyen Thi Thanh,Thuy, Dinh Thi Thu,Song, Seok Bean,Nam, Nguyen Hoai,Kiem, Phan Van,Kim, Young Ho,Minh, Chau Van WILEY‐VCH Verlag 2014 Chem Inform Vol.45 No.28
<P><B>Abstract</B></P><P>isolation, structure determination and antiinflammatory effects of nine cembranoid diterpenes including four new compounds, crassumols D—G (I)—(IV), respectively</P>
Nguyen Xuan Nhiem,Pham Hai Yen,Nguyen Thi Thanh Ngan,TRANHONG QUANG,Phan Van Kiem,Chau Van Minh,Bui Huu Tai,Nguyen Xuan Cuong,Seok Bean Song,김영호 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.4
Momordica charantia is used to treat various diseases, including inflammatory conditions. Previous reports indicated that the extract of this plant inhibits activation of nuclear transcription factor-jB (NF-jB) but activates peroxisome proliferator-activated receptor (PPAR). Additionally, cucurbitane-type triterpene glycosides are the main bioactive components of the fruit of M. charantia. Therefore, we investigated the anti-inflammatory activity of 17 cucurbitane-type triterpene glycosides (1–17) isolated from this plant. Their inhibition of NF-jB and activation of PPAR activities in HepG2 cells were measured using luciferase reporter and PPAR subtype transactivation assays. Compounds 6 and 8 were found to inhibit NF-jB activation stimulated by tumor necrosis factor-a (TNFa) in a dose-dependent manner. With 50% inhibition concentration (IC50) values of 0.4 lM, compounds 6 and 8 were more potent inhibitors than the positive control, sulfasalazine (IC50 = 0.9lM). Compounds 4, 6, and 8 also inhibited TNFa-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2mRNA. However, only compound 13 significantly increased PPARc transactivation.
( Nguyen Xuan Cuong ),( Duong Van Huy ) 한국국방연구원 2021 The Korean Journal of Defense Analysis Vol.33 No.2
The South China Sea is one of the world’s security hot spots regarding territorial sovereignty disputes among China, Taiwan and some Southeast Asian countries such as Vietnam, the Philippines, Malaysia and Brunei. Currently, the dispute situation in the South China Sea is increasingly complicated and tends to be more stressful because the region’s situation is not only heated up by territorial sovereignty disputes and geostrategic competition among great powers, but also by various non-traditional security issues, including fisheries security issues such as overfishing, illegal fishing activities, conflicts over fishery activities between countries. However, at present, there are no effective cooperative and rational mechanisms for fisheries in the South China Sea. Meanwhile, the Association of Southeast Asian Nations (ASEAN) is an important mechanism for managing regional security issues, including non-traditional security in the South China Sea. However, ASEAN’s role in this region is still relatively weak. Given this situation, the article analyzes the current situation of fisheries security issue in the South China Sea and clarifies how ASEAN’s role in this sector plays out in the current period. What actions should ASEAN take to contribute to ensuring non-traditional security in the South China Sea in general and fisheries security in particular?
국가 이미지와 관여도가 베트남 스마트폰 소비자의 구매결정에 미치는 영향
( Dao Xuan Cuong ),임달호 ( Dalho Lim ),신영애 ( Youngae Shin ) 한국유통경영학회 2021 유통경영학회지 Vol.24 No.6
Purpose: The purpose of this study is to understand the influence of various factors on smartphone purchase decisions in Vietnam and to investigate the effect of involvement and country image in the process. Research design, data, and methodology: In order to achieve the research purpose, a hypothesis and a research model were developed by to validate the proposed study model. First, an exploratory factor analysis was performed to confirm reliability and validity. a confirmatory factor analysis was conducted based on the reliability and exploratory factor analysis results. Finally, by checking the discriminant validity, we empirically tested hypotheses after comparing the correlation value with the root average variance extracted. Results: As a result, there is a control effect on the influence of product characteristics, friends, and family on the purchase decision in the process of factors affecting the purchase decision. Among them, there is evidence that brand awareness, family and friends are the most powerful factors. Research shows that product features, brand awareness, pricing, social influence, and family and friends positively influence smartphone purchase decisions. Among them, there is evidence that brand awareness, family and friends are the most powerful factors. Implications: This study identified the purchase decision factors of consumers in large cities of Vietn am. As a result, companies that in tend to advance to Vietnam should establish marketing strategies to heighten the brand image. Smartphones are high-priced products for consumers in Vietnam, so the products are thoroughly evaluated before purchasing them. Accordingly, product marketing tailored to the consumers in Vietnam is necessary.
Cytotoxic Oleane-type Triterpene Saponins from Glochidion eriocarpum
Nguyen Xuan Nhiem,김영호,Vu Kim Thu,Phan Van Kiem,Chau Van Minh,Bui Huu Tai,TRANHONG QUANG,Nguyen Xuan Cuong,Pham Hai Yen,Hye-Jin Boo,강정일,강희경 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.1
The anticancer activity of ten compounds from the aerial parts of Glochidion eriocarpum were evaluated on two human cancer cell lines, HL-60 and HCT-116. Compounds 1-4 displayed highly potent cytotoxic activity on the HCT-116 cancer cell line with IC50 values ranging of 0.41~1.16 μM. Compounds 1-4 significantly inhibited the HL-60 cell line with IC50 values ranging of 4.51~6.33 μM. These results suggested that the benzoyl group at the C-22 position in oleane-type triterpene saponins was essential for cytotoxicity towards tumor cells. Moreover, compounds 2 and 3 showed more potent cytotoxicity than compounds 1 and 4 against HL-60 and HCT-116 cells. With respect to the mechanism underlying cytotoxicity, compounds 1-4 increased chromatin condensation, a typical apoptotic characteristic in HL-60 and HCT-116 cells. In the mechanism of apoptosis induction, compounds 1-4 reduced Bcl-2expression, whereas the expression of Bax was increased compared to controls in HCT-116 cells. In addition, compounds 1-4 decreased the level of procaspase-3. The cleavage of poly (ADP-ribose) poly merase (PARP), a vital substrate of effector caspase, was observed in HCT-116 cells. Furthermore, the induction of apoptosis was also accompanied by an activation of extracellular signal-regulated kinase (ERK) and p38 kinase in HCT-116 cells. These findings provide evidence demonstrating that the pro-apoptotic effects of compounds 1-4 are mediated through the activation of ERK and p38 in HCT-116 cells.
Phenylpropanoid Glycosides from Heterosmilax erythrantha and Their Antioxidant Activity
Nguyen Xuan Nhiem,김영호,Phan Van Kiem,Chau Van Minh,Ninh Khac Ban,Nguyen Xuan Cuong,Bui Huu Tai 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.10
By various chromatographic methods, one new phenylpropanoid glycoside, heterosmilaside(1), two known phenylpropanoid glycosides, helonioside B (2), and 2',6'-diacetyl-3,6-diferuloyl sucrose (3), and three known flavonoids, isoquercetin (4), quercetin-3-O-β-D-glucuronopyranoside (5), and quercetin-3-O-(2''-α-L-rhamnopyranosyl)-β-D-glucuronopyranoside (6) were isolated from the methanolic extract of the aerial part of Heterosmilax erythrantha Baill. Their structures were elucidated on the basis of spectroscopic analyses. All the isolated compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 5 and 6 showed significant antioxidant activity with SC50 values of 3.7 and 6.5 μg/mL, respectively.
Inhibitory Activity of Plantago major L. on Angiotensin I-converting Enzyme
Nguyen Xuan Nhiem,김영호,Bui Huu Tai,Phan Van Kiem,Chau Van Minh,Nguyen Xuan Cuong,Nguyen Huu Tung,Vu Kim Thu,Trinh Nam Trung,Hoang Le Tuan Anh,조성훈,장해동,권영인 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.3
Eight compounds were isolated from methanol extract of Plantago major L. leaves and investigated for their ability to inhibit angiotensin I-converting enzyme activity. Among them, compound 1 showed the most potent inhibition with rate of 28.06 ± 0.21% at a concentration of 100 μM. Compounds 2 and 8 exhibited weak activities. These results suggest that compound 1 might contribute to the ability of P. major to inhibit the activity of angiotensin I- converting enzyme.
Nguyen, Xuan Cuong,Nguyen, Dinh Duc,Thi Loan, Nguyen,Chang, Soon Woong IWA Publishing 2017 Water Science & Technology Vol.76 No.2
<P>In this study, a pilot-scale integrated constructed wetland with vertical flow (VF) and horizontal flow (HF) in series was designed and investigated to evaluate sewage wastewater treatment capacity. The VF unit was planted with <I>Canna indica</I> and was 1.2 m long, 1.2 m wide, and 1.2 m high; whereas the HF unit contained <I>Colocasia esculenta</I> and was 3.0 m long, 1.0 m wide, and 1.0 m high. The system was operated under different hydraulic loading rates (HLRs) of 0.1, 0.2, and 0.15 m/d. The effluent concentrations differed as HLR changed, and the means were total suspended solids (TSS): 87 mg/L; biological oxygen demand (BOD<SUB>5</SUB>): 31 mg/L; chemical oxygen demand (COD<SUB>Cr</SUB>): 59 mg/L; ammonium nitrogen (NH<SUB>4</SUB>-N): 5.3 mg/L; nitrate nitrogen NO<SUB>3</SUB>-N: 8.4 mg/L; total nitrogen (TN): 7.1 mg/L; phosphate (PO<SUB>4</SUB>-P): 0.9 mg/L; and total coliforms (TCol): 1,485 most probable number (MPN)/100 mL. The average removal efficiencies for TSS, BOD<SUB>5</SUB>, TN, NH<SUB>4</SUB>-N, PO<SUB>4</SUB>-P, and TCol were 28.3, 74.9, 79, 76.2, 3.6, and 82%, respectively. There were significant differences in the effluent concentrations among the three HLRs (<I>P</I> < 0.05), except for PO<SUB>4</SUB>-P.</P>