FRACTAL ANALYSIS FOR FRACTURE PROCESS OF ROLYMER MATERIALS

Liu, Liu, Xiaobo,Gu, Gu, Yi,Jiang, Jiang, Luxia,Cai, Cai, Xingxian 한국재료학회 1995 Fabrication and Characterization of Advanced Mater Vol.1 No.3

This work focuses on fractal analysis for fracture process of polymer materials in theoric model and experimental ditermination. A series of theoric fractal model based on fracutred surface for fracutre process of polymer materials are founded, and the fractal dimension of fractured surface wa obtained under various break mechanism including crack in shear bands, crack development in stonely wave, crack cross, break in brittle, fractured pocess for the rigid filtered polymers and self-reinforced liquid crystal thermotes. These results retlected that the bigger the fractal dimensiion of the fractured surface, the higher the toughenss of polymer materials. According to Griffith strength, the mechanical properties of polymers increased lindarly with the rise of fractal dimension value.

Multi‑DoF wireless power transfer systems based on magnetic dipole coils with multiple receivers

Xiaobo Liu,Cancan Rong,Xiong Tao,Conghui Lu,Yingyin Zeng,Renzhe Liu,Minghai Liu 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.3

To improve the degree of freedom (DoF), and the multi-terminal power supply capability of wireless power transfer (WPT) systems, multi-DoF WPT systems for multiple pickups based on magnetic dipole coils are proposed in this paper, which can simultaneously charge multiple receivers regardless of the position degree. First, the equivalent circuit model of the magnetic dipole coils is provided. The critical factors of the proposed multi-load systems are analyzed, such as transfer efficiency, power distribution, and optimal load. Second, a multi-load wireless power transfer system with equal transmitting (TX) and receiving (RX) coil is designed, and the misalignment tolerance of lateral and rotating occasions for the RX coils is discussed. In particular, a multi-load WPT system with miniaturized step-laminated receivers is implemented based on the magnetic dipole coils. Finally, experimental prototypes are established. The obtained results indicate that the output power for the equal dual-load WPT system can reach more than 78 W with a total efficiency of more than 80% under a transfer distance of length of the receiving coil winding. In addition, the output power of the non-equal four-load WPT system can reach 30 W with a total efficiency of 86%. The proposed systems provide practical guidance for the future development of multi-DoF WPT systems for use in portable devices, unmanned intelligent systems, and smart household applications.

Correlation between red blood cell distribution width/platelet count and prognosis of newly diagnosed diffuse large B-cell lymphoma

Xiaobo Liu,Yanliang Bai,Ying Liu,Weiya Li,Yabin Cui,Jinhui Xu,Xingjun Xiao,Xiaona Niu,Kai Sun 대한혈액학회 2023 Blood Research Vol.58 No.4

Background Red blood cell distribution width/platelet count ratio (RPR) is a reliable prognostic assessment indicator for numerous diseases. However, no studies to date have examined the relationship between RPR and the prognosis of diffuse large B-cell lymphoma (DLBCL). Therefore, this study aimed to investigate the correlation between RPR and the clinical characteristics and prognosis of patients with diffuse large B-cell lymphoma. Methods We retrospectively studied 143 patients with newly diagnosed DLBCL and used the median value as the RPR threshold. We also investigated the correlation of pretreatment RPR level with clinical characteristics and its impact on DLBCL prognosis. Results Using the median value as the cut-off, patients with DLBCL were divided into a low RPR group (<0.0549) and a high RPR group (≥0.0549). Patients in the high RPR group were older, had a later Ann Arbor stage, were prone to bone marrow invasion, and had a higher National Comprehensive Cancer Network International Prognostic Index score (P < 0.05). A survival analysis showed that progression-free survival (PFS) (P =0.003) and overall survival (OS) (P <0.0001) were significantly shorter in the high versus low RPR group. A multifactorial Cox analysis showed that bone marrow invasion and elevated lactate dehydrogenase (LDH) were separate risk factors for PFS (P <0.05), while an RPR ≥0.0549 and elevated LDH were separate risk factors for OS (P <0.05). Conclusion A high RPR (≥0.0549) in patients with newly diagnosed DLBCL is an independent risk factor for a poor prognosis.

Cross-Linked Sulfonated Poly(arylene ether nitrile)s with Low Swelling and High Proton Conductivity

Jingchun Liu,Penglun Zheng,Mengna Feng,Renbo Wei,Xiaobo Liu 한국고분자학회 2017 Macromolecular Research Vol.25 No.12

A series of cross-linked composite membranes were prepared from sulfonated poly (arylene ether nitrile) (SPEN) and 2, 5-diaminobenzensulfonic acid (DABSA) via a direct cross-linking method aiming to obtain low-swelling and excellent proton conductivity membrane. This experiment had two advantages: expectant low-swelling in the extreme temperatureand excellent proton conductivity. Besides, all cross-linked membranes showed excellent thermal stability which exhibiting a temperature of initial decomposition about 250 °C. The membranes showed the IEC values varying from 1.449 to 1.675 mmol·g-1. The result suggested that the SPEN-DABSA membranes are potential candidates as PEM in DMFCs.

Culture-Positive Spontaneous Ascitic Infection in Patients with Acute Decompensated Cirrhosis: Multidrug-Resistant Pathogens and Antibiotic Strategies

Jing Liu,Yanhang Gao,Xianbo Wang,Zhiping Qian,Jinjun Chen,Yan Huang,Zhongji Meng,Xiaobo Lu,Guohong Deng,Feng Liu,Zhiguo Zhang,Hai Li,Xin Zheng 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.2

Purpose: This study investigated multidrug-resistant (MDR) pathogens and antibiotic strategies of culture-positive spontaneousascitic infection (SAI) in patients with acute decompensated cirrhosis. Materials and Methods: We retrospectively analyzed 432 acute decompensated cirrhotic patients with culture-positive SAI from11 teaching hospitals in China (January 2012 to May 2018). A Cox proportional hazards model analysis was conducted to identifyindependent predictors of 28-day mortality. Results: A total of 455 strains were isolated from 432 ascitic culture samples. Gram-negative bacteria (GNB), gram-positive bacteria(GPB), and fungi caused 52.3, 45.5, and 2.2% of all SAI episodes, respectively. Episodes were classified as nosocomial (41.2%), healthcare-related (34.7%), and community-acquired (24.1%). Escherichia coli (13.4%) and Klebsiella pneumoniae (2.4%) were extendedspectrumβ-lactamase producing isolates. The prevalence of methicillin-resistant Staphylococcus aureus was 1.1%. Ceftazidime,cefepime, aztreonam, and amikacin were recommended as first-line antibiotics agents for non-MDR GNB infections; piperacillin/tazobactam and carbapenems for MDR GNB in community-acquired and healthcare-related or nosocomial infections, respectively;and vancomycin or linezolid for GPB infections, regardless of drug-resistance status. Multivariate analysis revealed days ofhospital stay before SAI, upper gastrointestinal bleeding, white blood cell count, alanine aminotransferase, serum creatinine concentration,total bilirubin, and international normalized ratio as key independent predictors of 28-day mortality. Conclusion: MDR pathogens and antibiotic strategies were identified in patients with acute decompensated cirrhosis with culture-positive SAI, which may help optimize therapy and improve clinical outcomes.

A Fractal-Interpolation Model for Diagnosing Spalling Risk in Concrete at Elevated Temperatures

Caiwei Liu,Chaofeng Liu,Wenlong Xu,Xiaobo Zhang,Yue Lan 대한토목학회 2018 KSCE Journal of Civil Engineering Vol.22 No.12

Spalling risk analysis and assessment of fire-loaded concrete structures is an essential part of research on fire-resistant behavior of concrete structures. In this work, the authors developed a stochastic interpolation-based fractal model capable of quickly assessing spalling risk in concrete at high temperatures based on mainly factors affecting explosive spalling. The preliminary grading standard of the factors elected in the study was established based on the data from literature. Test samples were then generated by the stochastic interpolation method according to uniform distribution. A spalling risk diagnosis model was built based on fractal dimension weights. In addition, 10 specimens were assessed with the presented model. The evaluation results obtained by the model in this study were in good agreement with those obtained by the fuzzy pattern recognition approach and coincided well with the actual fire test results. The applicability and reliability of the proposed model were verified and can provide theoretical support for identification of the spalling risk of concrete at elevated temperatures.

Identification of Novel Subregions of LOH in Gastric Cancer and Analysis of the HIC1 and TOB1 Tumor Suppressor Genes in These Subregions

Jingcui Yu,Songbin Fu,Peng Liu,Xiaobo Cui,Yu Sui,Guohua Ji,Rongwei Guan,Donglin Sun,Wei Ji,Fangli Liu,An Liu,Yuzhen Zhao,Yang Yu,Yan Jin,Jing Bai,Jingshu Geng,Yingwei Xue,Jiping Qi,Ki-Young Lee 한국분자세포생물학회 2011 Molecules and cells Vol.32 No.1

Previously, we identified 3 overlapping regions showing loss of heterozygosity (LOH, R_1-R_3 from 11 to 30 cM) on chromosome 17 in 45 primary gastric cancers (GCs). The data indicated the presence of tumor suppressor genes (TSGs) on chromosome 17 involved in GC. Among the putative TSGs in these regions, HIC1 (in SR_1) and TOB1 (in SR_3) remain to be examined in GC. By immunohistochemistry (IHC), methylation-specific PCR (MSP) and western blot, we evaluated the expression and regulation status for HIC1 and TOB1 protein in GC. We narrowed down the deletion intervals on chromosome 17 and defined five smaller LOH subregions, SR_1-SR_5 (0.54 to 3.42 cM), in GC. We found that HIC1 had downregulated expression in 86% (91/106) and was methylated in 87% (26/30) of primary GCs. Of the primary GCs showing downregulation of HIC1 protein, 75% (18/24) had methylated HIC1 gene. TOB1 was either absent or expressed at reduced levels in 75% (73/97) of the GC samples. In addition, a general reduction was found in total and the ratio of unphosphorylated to phosphorylated TOB1 protein levels in the differentiated GC cell lines. Further analysis revealed significant simultaneous downregulation of both HIC1 and TOB1 protein in GC tissue microarray samples (67%, 52/78) and in primary GCs (65%, 11/17). These results indicate that silencing of HIC1 and TOB1 expression is a common occurrence in GC and may contribute to the development and progression of the disease.

Research on Protection and Inheritance Strategy of Endangered Traditional Ceramic Crafts in Southern Fujian Folklore

Xiaobo Lian,Qingnian Zhang,Linping Zhou,Yuntao Huang,Zhouqing Liu KOREA INSTITUTE FOR HUMANITIES AND SOCIAL SCIENCES 2024 Journal of Arts and Cultural Studies(ACS) Vol.3 No.1

Background: In recent years, China's established many institutions and introduced reform programs to protect cultural heritage. Purpose:This research analyzes the protection status and development mode of endangered traditional ceramics in southern Fujian to better protect the endangered traditional ceramic technology in southern Fujian. It further researches ceramic process protection and inheritance development strategy. Methods: The attitudes of relevant national organizations towards protecting endangered traditional crafts are analyzed in the ceramic factory areas around Chaoshan and Foshan. The Dehua white porcelain, Jingdezhen porcelain mothers, and Foshan Shiwan dolls are compared through comparative research and literature to study various methods for protecting endangered traditional crafts. Further analyses on the strategies for the protection and development of the inheritance of endangered traditional ceramic crafts in the folklore of southern Fujian are also performed. Results: This article analyzes the protection and inheritance strategies of traditional ceramic crafts endangered in southern Fujian. It summarizes the three inheritance strategies of supporting inheritance talents, improving the protection mechanism, and establishing the protection and inheritance of traditional ceramic crafts on campus. Conclusion: The study of ceramic process protection strategy can summarize three points. First, to strengthen the precision support; second, to improve the inheritance and protection mechanism; and third, to establish research on the protection and inheritance of traditional ceramic processes.

Distributed Fuzzy Extended Kalman Filter for Multiagent Systems

Xiaobo Zhang,Haoshen Lin,Gang Liu,Bing He 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.5

In this study, a novel distributed Kalman filter based on a possibilistic framework was proposed to mitigate fuzzy noisein nonlinear multiagent systems. To describe fuzzy uncertainty, noises were modeled as fuzzy random variables with trapezoidal probability distributions instead of Gaussian distributions. A fuzzy information fusion (FIF) algorithm was proposed to fuse fuzzy state estimations from neighboring nodes. The nonlinear problem was solved by using local linearization. A distributed extended fuzzy information filter was designed by combining the FIF algorithm and local linearization in distributed sensor networks. The stability of this filter was analyzed. Finally, a target tracking simulation was performed to detail the effectiveness of the proposed filter algorithm.

Panduratin A Inhibits Cell Proliferation by Inducing G0/G1 Phase Cell Cycle Arrest and Induces Apoptosis in Breast Cancer Cells

Liu, Qiuming,Cao, Yali,Zhou, Ping,Gui, Shimin,Wu, Xiaobo,Xia, Yong,Tu, Jianhong The Korean Society of Applied Pharmacology 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.3

Because of the unsatisfactory treatment options for breast cancer (BC), there is a need to develop novel therapeutic approaches for this malignancy. One such strategy is chemotherapy using non-toxic dietary substances and botanical products. Studies have shown that Panduratin A (PA) possesses many health benefits, including anti-inflammatory, anti-bacterial, anti-oxidant and anticancer activities. In the present study, we provide evidence that PA treatment of MCF-7 BC cells resulted in a time- and dose-dependent inhibition of cell growth with an $IC_{50}$ of $15{\mu}M$ and no to little effect on normal human MCF-10A breast cells. To define the mechanism of these anti-proliferative effects of PA, we determined its effect critical molecular events known to regulate the cell cycle and apoptotic machinery. Immunofluorescence and flow cytometric analysis of Annexin V-FITC staining provided evidence for the induction of apoptosis. PA treatment of BC cells resulted in increased activity/expression of mitochondrial cytochrome C, caspases 7, 8 and 9 with a significant increase in the Bax:Bcl-2 ratio, suggesting the involvement of a mitochondrial-dependent apoptotic pathway. Furthermore, cell cycle analysis using flow cytometry showed that PA treatment of cells resulted in G0/G1 arrest in a dose-dependent manner. Immunoblot analysis data revealed that, in MCF-7 cell lines, PA treatment resulted in the dose-dependent (i) induction of $p21^{WAF1/Cip1}$ and p27Kip1, (ii) downregulation of Cyclin dependent kinase (CDK) 4 and (iii) decrease in cyclin D1. These findings suggest that PA may be an effective therapeutic agent against BC.