1990년대 강우석 영화의 서울 공간 재현

장우진(Chang, Woo Jin) 한국영화학회 2018 영화연구 Vol.0 No.75

이 글은 가장 대중적인 상업영화 감독으로 인정받는 강우석 감독의 1990년대 영화가 서울의 주거공간과 도시공간을 어떻게 재현하고 있는지 논의한다. 분석대상은 서울 올림픽 이후부터 IMF 사태 발생 전까지 제작된 〈행복은 성적순이 아니잖아요〉(1989), 〈나는 날마다 일어선다〉(1990), 〈누가 용의 발톱을 보았는가〉(1991), 〈미스터 맘마〉(1992), 〈투캅스〉(1993), 〈마누라 죽이기〉(1994), 〈투캅스2〉(1996)이며, 이들 작품은 모두 서울을 공간적 배경으로 한다는 공통점이 있다. 이 글이 제기하는 질문은 세 가지이다. 첫째, 1990년대 서울 공간 변화의 특징이 무엇인가? 둘째, 1990년대 강우석의 영화들은 서울의 주거공간과 도시공간을 어떻게 재현하고 있는가? 셋째, 그러한 주거공간과 도시공간의 영화적 재현을 통해 우리가 독해할 수 있는 당대의 가치체계나 욕망, 불안 등은 어떠한 것인가? 1990년대는 경제적 호황과 더불어 중산층이 급부상한 시기였다. 이 시기에 서울은 아파트 단지가 대규모로 개발되었고 교통망이 크게 확충되었다. 이에 따라 도시 분산화가 이루어졌고, 아파트는 서울 중산층의 대표적 주거공간이 되었다. 강우석의 영화는 1991년까지 주로 현실 비판의 영화였으며, 아파트를 부정적 이미지로 재현하였다. 그러나 1992년 이후 아파트는 중산층 인물의 평범하고도 일상적인 주거공간으로 제시되었다. 이는 당시 아파트가 중산층이 소유하기를 원하는 욕망의 대상이 된 현실을 반영한 것이며, 강우석의 영화는 현실과 동경의 어색한 부정교합 형태로 중산층의 욕망을 소비하게 만들었다. 또한, 당시 한국영화가 도시의 화려함에 주목한 반면, 강우석의 영화는 개발이 되지 않았거나 이미 버려진 도시의 주변공간을 주목하는 경향이 있었다. 이것은 발전의 미완을 상기시켜 주었다. 한편, 강우석의 영화는 새로운 도시공간으로서 자동차 실내공간을 제시하였다. 당시 중산층의 사적 욕망과 소비 대상이었던 자동차의 실내공간은 이제 개인의 자유와 프라이버시가 보장된 은밀한 사적 공간으로 재현되었다. This paper discusses how are the residential and urban spaces in Seoul represented in the 1990s movies directed by Kang Woo-suk who was recognized as the most popular commercial film director in Korea. The subjects of the analysis are as follows: 〈행복은 성적순이 아니잖아요〉(1989), 〈나는 날마다 일어선다〉(1990), 〈누가 용의 발톱을 보았는가〉(1991), 〈미스터 맘마〉(1992), 〈투캅스〉(1993), 〈마누라 죽이기〉(1994), 〈투캅스2〉(1996). All of these have a common thing that they have a spatial background in Seoul. There are three questions that this paper poses. First, what are the characteristics of spatial change in Seoul during the 1990s? Second, how did the films of Kang Woo-suk in the 1990s reproduce the residential and urban spaces in Seoul? Third, what are the value systems, desires, and anxieties of those days that we can read through the cinematic representation of residential spaces and urban spaces? The 1990s was a time when the middle class emerged with economic boom. At this time, apartment complexes were developed on a large scale in Seoul and the transportation network was greatly expanded. As a result, urban decentralization has been achieved, and the apartment has become a representative residential space of the middle class in Seoul. Kang Woo-suk ‘s movies were mainly films of criticism of reality until 1991, and they reproduced the apartments as negative images. However, since 1992, apartments have been presented as ordinary and everyday living spaces of middle class people in his movies. This reflects the fact that the apartment was the object of desire to be owned by the middle class at that time, and Kang Woo-suk’s movie made spectators consume the desire of the middle-class in the form of awkward malocclusion of reality and longing. In addition, while Korean films generally paid attention to the splendor of the city, Kang Woo-suk’s films tended to pay attention to the surrounding space of the city that had not been developed or had been abandoned. This reminded us of the incompleteness of development. On the other hand, Kang Woo-suk’s movies presented the interior space of a car as a new urban space. The interior space of a car, the target of private desires and consumptions of middle class, became represented as a private urban space with individual freedom and privacy guaranteed.

아세틸 콜린 유발 검사시 허혈성 심전도 변화와 흉통의 발생이 내피세포 기능장애에 미치는 영향

최철웅(Cheol Ung Choi),나승운(Seung-Woon Rha),김선원(Sun Won Kim),나진오(Jin Oh Na),임홍의(Hong Euy Lim),김진원(Jin Won Kim),김응주(Eung Ju Kim),한성우(Seong Woo Han),박창규(Chang Gyu Park),서홍석(Hong Seog Seo),오동주(Dong Joo Oh) 대한임상노인의학회 2010 대한임상노인의학회지 Vol.11 No.4

연구배경: 아세틸 콜린 유발 검사시 발생하는 흉통과 허혈성 심전도 변화가 아세틸 콜린에 의해 발생하는 관상동맥의 내피세포 기능에 어떤 영향을 주는지 알아보고자 했다. 방법: 흉통으로 내원하여 관상동맥 조영술과 아세틸 콜린 유발검사를 시행받은 1,085명의 환자를 대상으로 하였다. 아세틸 콜린 유발 검사를 하는 동안 허혈성 심전도 변화 및 흉통의 발생 유무에 따른 관상동맥 내피세포 기능의 특징을 비교하였다. 결과: 539명의 환자에서 아세틸 콜린 검사시 내피세포 기능 장애가 발생 하였다. 허혈성 심전도 변화가 있었던 그룹이 심전도 변화가 없었던 그룹보다 흉통이 더 많았고(78.1% vs. 60.8%, P=0.007), 관상동맥 조영술상 다발성 관상동맥 경련이 빈번하였고(59.4% vs. 40.6%, P=0.004), 관상동맥의 경련 정도도 더 심하였다(64.1% vs. 46.5%, P=0.006). 흉통이 있었던 그룹이 흉통이 없었던 그룹보다 허혈성 심전도 변화의 빈도가 더 높았다(14.7% vs. 7.5%, P=0.007). 또한 흉통이 있었던 그룹이 관상동맥 경련이 다발성으로 발생하는 경우가 많았고 (50.7% vs. 29.5%, P<0.001), 미만성으로 발생하는 경우가 많았고(87.1% vs. 75%, P<0.001), 관상동맥의 경련의 정도도 더 심하였다(51.6% vs. 43.5%, P=0.041). 결론: 아세틸 콜린 유발검사시 발생하는 허혈성 심전도 변화와 흉통은 관상동맥 경련의 정도와 경련이 발생하는 관상동맥 개수와 연관이 있다. Background: ECG changes and chest pain during acetylcholine (Ach) provocation tests may constitute important clinical parameters for Ach-induced endothelial dysfunction. We investigated the association between ischemic ECG changes and chest pain during the Ach-provocation test and angiographic characteristics of Ach-induced endothelial dysfunction. Methods: A total of 1,085 patients with anginal symptoms underwent diagnostic coronary angiography (CAG) and Ach-provocation tests. We compared angiographic characteristics of Ach-induced endothelial dysfunction according to the presence of ECG change and chest pain. Results: A total of 539 patients experienced Ach-induced endothelial dysfunction. Patients who experienced ECG change group suffered more frequent chest pain (78.1% vs. 60.8%, P=0.007), angiographically more frequent multiple coronary artery spasm (59.4% vs. 40.6%, P=0.004), and more severe coronary artery spasm (64.1% vs. 46.5%, P=0.006) than patients without ECG change. However, there was no difference in the length of endothelial dysfunction between the groups. The incidence of ischemic ECG changes in patients with chest pain was higher than in patients without chest pain (14.7% vs. 7.5%, P=0.007). Patients who experienced chest pain more often experienced multiple (50.7% vs. 29.5%, P<0.001), diffuse (87.1% vs. 75%, P<0.001), and severe coronary artery spasm (51.6% vs. 43.5%, P=0.041) than patients without chest pain. Conclusion: Ischemic ECG changes and chest pain during the Ach-provocation test are associated with multi-vessel involvement and severe coronary artery spasm. Chest pain is associated with the length of endothelial dysfunction, but ischemic ECG change is not.

Projections of summertime ozone concentration over East Asia under multiple IPCC SRES emission scenarios

Lee, Jae-Bum,Cha, Jun-Seok,Hong, Sung-Chul,Choi, Jin-Young,Myoung, Ji-Su,Park, Rokjin J.,Woo, Jung-Hun,Ho, Changhoi,Han, Jin-Seok,Song, Chang-Keun Elsevier 2015 Atmospheric environment Vol.106 No.-

<P><B>Abstract</B></P> <P>We have developed the Integrated Climate and Air Quality Modeling System (ICAMS) through the one-way nesting of global–regional models to examine the changes in the surface ozone concentrations over East Asia under future climate scenarios. Model simulations have been conducted for the present period of 1996–2005 to evaluate the performance of ICAMS. The simulated surface ozone concentrations reproduced the observed monthly mean concentrations at sites in East Asia with high R<SUP>2</SUP> values (0.4–0.9), indicating a successful simulation to capture both spatial and temporal variability. We then performed several model simulations with the six IPCC SRES scenarios (A2, A1B, A1FI, A1T, B1, and B2) for the next three periods, 2016–2025 (the 2020s), 2046–2055 (the 2050s), and 2091–2100 (the 2090s). The model results show that the projected changes of the annual daily mean maximum eight-hour (DM8H) surface ozone concentrations in summertime for East Asia are in the range of 2–8 ppb, −3 to 8 ppb, and −7 to 9 ppb for the 2020s, the 2050s, and the 2090s, respectively, and are primarily determined based on the emission changes of NO<SUB>x</SUB> and NMVOC. The maximum increases in the annual DM8H surface ozone and high-ozone events occur in the 2020s for all scenarios except for A2, implying that the air quality over East Asia is likely to get worse in the near future period (the 2020s) than in the far future periods (the 2050s and the 2090s). The changes in the future environment based on IPCC SRES scenarios would also influence the change in the occurrences of high-concentrations events more greatly than that of the annual DM8H surface ozone concentrations. Sensitivity simulations show that the emissions increase is the key factor in determining future regional surface ozone concentrations in the case of a developing country, China, whereas a developed country, Japan would be influenced more greatly by effects of the regional climate change than the increase in emissions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Change in ozone level is determined by the combination of NO<SUB>x</SUB> and NMVOC emissions. </LI> <LI> Ozone level over East Asia would get worse in the near future (the 2020s) than far future. </LI> <LI> A high-concentration event generally increases and more frequently occurs in the future. </LI> <LI> Change in ozone air quality in a developing country depends more on emissions change. </LI> <LI> Change in ozone air quality in a developed country depends more on climate change. </LI> </UL> </P>

Carotenoids 식이와 알코올이 혈액학적 성분과 간조직에 미치는 영향에 관한 연구

조만희,김연선,이상한,우기민,장예진,김창세 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Alcohol is well known agent which can damage the human tissues such as liver via stimulating lipid peroxidation and storage, denaturation of macromolecules, and inhibiting protein metabolism. On the other hand, carotenoids in addition to vitamins A, C, E and lipoic acid, play important roles in protecting these oxidative damages as well as preventing the production of free radicals. This study was carried out to elucidate the precise effects of alcohol administration into rats on the antioxidative functions of dietary carotenoids and isolated β-carotene, and to find out any parameters to uncover more detailed biochemical mechanisms of these agents. For these purposes, two different approaches were performed: 1) examination of the changes in hematological parameters (e.g., total proteins, A/G ratio, ALT/AST et. al) and statistical correlations among inter- and intragroups, 2) examination of the histopathological changes by an electron microscope. The results were analyzed and summarized as following; (1) Carrot diet for one week caused a slight increase in albumin. A/G ratio and AST levels, and a slight decrease in ALT, ALP, BUN and uric acid levels. Two-week alcohol administration following carrot diet increased total proteins, albumin A/G ratio and BUN levels. However, both groups were shown to have little significant changes in cholesterol concentrations. (2) Cheese diet for one week caused a significant increase in total proteins, albumin, AST, ALP, uric acid and total cholesterol levels, and a significant decrease in A/G ratio and glucose concentrations. However, two-week β-carotene diet following cheese intake increased total proteins albumin, A/G ratio, BUN and total cholesterol levels, whereas AST, ALT, ALP and uric acid levels were decreased. (3) Alcohol administration for one week caused an increase in AST activities and a decrease in total proteins, albumin, ALT, ALP and BUN levels. A successive β-carotene diet following alcohol administration increased total proteins, albumin, ALT, ALP and BUN levels, whereas decreased AST and uric acid levels. However, there were not significant changes in A/G ratio, glucose and total cholesterol levels in both groups. (4) β-carotene diet for one week caused a slight increase in albumin, glucose, AST and uric acid levels, and a slight decrease in ALP and BUN levels. Two-weeks alcohol administration following β-carotene diet increased albumin, glucose, BUN and total cholesterol levels, whereas decreased AST, ALT, ALP and uric acid levels. (5) Although the pathological investigation on the liver did not reveal significant changes, cheese diet group (CH-BC/1-CH) was shown to have some lipid deposits. Some results were unexpected and different from typical hematological changes shown by other researchers. Nonetheless, these results strongly suggest that the liver damage or hepatism caused by alcohol intake affects many kinds of biochemical metabolisms, which results in significant changes in many hematological parameters. In addition, dietary carotenoid and isolated β-carotene were shown to have protective roles against the biochemical changes by alcohol intake.

안전상비의약품 판매 이후 중독환자 특성 변화

김창영,이의중,이성우,김수진,한갑수,Kim, Chang Yeong,Lee, Eui Jung,Lee, Sung Woo,Kim, Su Jin,Han, Kap Su 대한임상독성학회 2018 대한임상독성학회지 Vol.16 No.1

Purpose: On November 15, 2012, sales of OTC (Over-The-Counter) drugs began at convenience stores, which changed the accessibility of some drugs. As a result, the exposure and access patterns of these drugs could have changed. In this study, we reviewed the changes in the characteristics of drug poisoning patients because of the reposition of nonprescription drugs according to the revised Pharmaceutical Affairs Act. Methods: A retrospective study was conducted to evaluate changes in characteristics of drug poisoning patients between 2008 and 2016. A registry was developed by an emergency medical center in a local tertiary teaching hospital, and patients who visited the center were enrolled in this registry. We compared two periods, from 2008 to 2012 (Pre OTC) and from 2013 to 2016 (Post OTC), for type of intoxicant, time from poisoning to visiting the emergency center, intention, psychiatric history, previous suicidal attempt, alcohol status, and emergency room outcomes. The primary outcome was the number of patients who took acetaminophen and NSAIDs (nonsteroidal anti-inflammatory drugs). Secondary outcomes were ICU admission rate, mortality rate, and number of patients who visited the ER when the pharmacy was closed after taking acetaminophen and NSAIDs (nonsteroidal anti-inflammatory drugs). Results: Among 1,564 patients, 945 and 619 patients visited the emergency room during pre and post OTC periods. The number of patients with acetaminophen and NSAIDs poisoning decreased from 9.2% to 6.1% (p=0.016). The ICU admission rate and mortality rate in the emergency room did not show significant results in the relevant patient groups, and so was the number of patients visiting ER when the pharmacy was closed taking acetaminophen and NSAIDs. Conclusion: Despite the sales of nonprescription drugs at convenience stores, the number of acetaminophen and NSAIDs poisoning patients decreased.

Thermoplasma acidophilum의 20S Proteasome에 의한 ATPase-활성적 단백질분해에 관한 연구

우기민,장예진,조만희,김창세,김완종,조성호,이상한 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

The eukaryotic 26S proteasome is an ATP/ubiquitin-dependent proteolytic complex consisting of the 20S core particle and 19S ATPase complex. However, because of its complexity and unstable properties, this study was carried out to present more simple and stable model for the ATP-activated proteolytic complex in prokaryotes which can take the place of the eukaryotic 26S proteasome. For this purpose, recombinant Thermoplasma 20S proteasome (T20S) and Methanococcus MS4, a sequence homolog of one ATPase subunit in the 19S ATPase complex, were successfully isolated from Escherichia coli (E. coli). The α and β subunits of T20S expressed in E. coli could assemble for themselves, and showed the peptide-hydrolyzing activity. Whereas both T20S and R20S (the 20S complex from rabbit skeletal muscle) had the highest peptidase activity against Suc-LLVY-AMC, a good substrate for chymotrypsin-like peptidase activity, the specific activity of T20S was slightly lower than that of R20S. In addition, several reagents such as KCI, SDS, and ovalbumin were shown to have different effects on the peptidase activities between T20S and R20S. When the ATPase activity of the purified MS4 were assayed , the Km for ATP was about 0.5 mM, and casein could stimulate the activity more than 2 fold without the change in Km. This result implicates that protein-activated ATPase may induce the conformational change of casein, and therefore suggests that MS4 ATPase may activate the proteolytic activity of the 20S proteasome via accelerating the recognition and translocation of the protein substrates.

P177 Dermoscopic findings during the course of β -blocker treatment for infantile hemangioma

( Jin-hwa Son ),( Hyun-ju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Jeong-min Kim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Byung-soo Kim ),( Moon-bum Kim ),( Hyun-chang Ko ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Dermoscopy is a useful tool for examining morphology and structure of blood vessels in vascular skin lesions like infantile hemangioma (IH). However, dermoscopic findings are not fully elucidated in the course of β-blocker treatment for IH. Objectives: To investigate changes of dermoscopic findings during the course of β-blocker treatment for IH. Methods: Superficial or mixed-type IH patients treated with topical timolol solution or oral propranolol were enrolled in Pusan National University Hospitals (Busan and Yangsan) from November 2011 to January 2016. Clinical photograph and dermoscopic findings were recorded and assessed at the baseline, 1, 2, 3 and 6 months. Results: Total 115 patients (male: 38 and female: 77 / superficial type: 48 and mixed type: 67 / timolol: 77 and propranolol: 38) were included. Diffuse light erythema tended to be diminished but milky-red area increased gradually during the course of treatment. The patients treated with oral propranolol showed more prominent changes on each dermoscopic findings than those treated with topical timolol (p=0.023 and p=0.018, respectively). But, other findings like red-globular vessels, red-dot vessels, red-circulated vessels, red-linear vessels did not show significant changes. Conclusion: Dissolution of diffuse light erythema and increase of milky-red area were significant dermoscopic findings in accordance with clinical improvement after β -blocker therapy for IH.

Microfluidic room temperature ionic liquid droplet generation depending on the hydrophobicity and interfacial tension

Woo-Jin Chang,Jung Wook Hwang,Joo-Hyung Choi,최범준,이규도,이상우,구윤모 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.1

We have characterized micro-droplet generation using water immiscible hexafluorophosphate ([PF6])- and bis(trifluoromethylsulfonyl)imide ([Tf2N])-based room temperature ionic liquids (RTILs). The interfacial tension between total 7 RTILs and phosphate buffered saline (PBS) was measured using a tensiometer for the first time. PBS is one of the most commonly used buffer solutions in cell-related researches. The measured interfacial tension ranges from 8.51 to 11.62 and from 9.56 to 13.19 for [Tf2N]- and [PF6]-based RTILs, respectively. The RTILs micro-droplets were generated in a microfluidic device. The micro-droplet size and generation frequency were determined based on continuous monitoring of light transmittance at the interface in microchannel. The size of RTIL micro-droplets was inversely proportional to the increase of PBS solution flow rate and RTILs hydrophobicity, while droplet generation frequency was proportional to those changes. The measured size of RTILs droplets ranged from 0.6 to 10.5 nl, and from 1.0 to 17.1 nl for [Tf2N]- and [PF6]-based RTILs, respectively. The measured frequency of generated RTILs droplets ranged from 2.3 to 37.2 droplet/min, and from 2.7 to 17.1 droplet/min for [Tf2N]- and [PF6]-based RTILs, respectively. The capillary numbers were calculated depending on the RTILs, and ranged from 0.51×10−3 to 1.06×10−3 and from 5.00×10−3 to 8.65×10−3, for [Tf2N]- and [PF6]-based RTILs, respectively. The interfacial tension between RTILs and PBS will contribute to developing bioprocesses using immiscible RTILs. Also, the RTILs micro-droplets will enable the high-throughput monitoring of various biological and chemical reactions using RTILs as new reaction media.

Treatment with spironolactone in Becker`s nevus associated with ipsilateral breast hypoplasia

( Jin Hwa Son ),( Hyunju Jin ),( Hyang Suk You ),( Woo Haing Shim ),( Jeong Min Kim ),( Margaret Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ),( Gun Wook Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Becker nevus syndrome is the association of becker``s nevus with breast hypoplasia and other ipsilateral bone or muscle changes. It is considered to be a hormone-dependent disorder caused by a disturbance in the activity of the androgen receptor. The receptor appears to be increased in Becker``s nevus, which may influence to the development of associated lesions. Herein, we report a case of Becker nevus syndrome improved after the treatment with spironolactone. A 13-year-old girl presented with well-defined brownish patch over left breast for 8 years. In addition, she noticed hypoplasia of her ipsilateral breast (12 x 10 cm) since 10 years age. Histopathologic examinations revealed acanthosis, elongation of rete ridges in epidermis and hyperpigmentation of the basal epidermal layer. The diagnosis has been confirmed to Becker``s nevus associated with ipsilateral breast hypoplasia. The Laboratory test (CBC, electrolytes, and LH/FSH) done and showed normal range. Her hypoplastic breast was treated with spironolactone with 50mg single dosage twice daily. She experienced mild menstrual irregularity and it was improved within 1 month. The left breast had enlarged abruptly to 13 x 10.5 cm after the treatment of 19 weeks.

Case Reports : Papular Mucinosis Associated with Systemic Lupus Erythematosus

( Woo Jin Lee ),( Gyeong Hun Park ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ),( Kee Chan Moon ),( Jai Kyoung Koh ) 대한피부과학회 2008 Annals of Dermatology Vol.20 No.4

Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower back of a 32-year-old man with systemic LE. It is interesting that he didn`t display any other skin manifestations of LE such as malar rash, discoid rash and photosensitivity during the previous 2 years. He achieved remission of his PNM without recurrence after 5 months treatment with topical steroids, in addition to receiving systemic antimalarials and steroids. (Ann Dermatol (Seoul) 20(4) 233∼236, 2008)