Black box-assisted fine-grained hierarchical access control scheme for epidemiological survey data

Xueyan Liu,Ruirui Sun,Linpeng Li,Wenjing Li,Tao Liu 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.9

Epidemiological survey is an important means for the prevention and control of infectious diseases. Due to the particularity of the epidemic survey, 1) epidemiological survey in epidemic prevention and control has a wide range of people involved, a large number of data collected, strong requirements for information disclosure and high timeliness of data processing; 2) the epidemiological survey data need to be disclosed at different institutions and the use of data has different permission requirements. As a result, it easily causes personal privacy disclosure. Therefore, traditional access control technologies are unsuitable for the privacy protection of epidemiological survey data. In view of these situations, we propose a black box-assisted fine-grained hierarchical access control scheme for epidemiological survey data. Firstly, a black box-assisted multi-attribute authority management mechanism without a trusted center is established to avoid authority deception. Meanwhile, the establishment of a master key-free system not only reduces the storage load but also prevents the risk of master key disclosure. Secondly, a sensitivity classification method is proposed according to the confidentiality degree of the institution to which the data belong and the importance of the data properties to set fine-grained access permission. Thirdly, a hierarchical authorization algorithm combined with data sensitivity and hierarchical attribute-based encryption (ABE) technology is proposed to achieve hierarchical access control of epidemiological survey data. Efficiency analysis and experiments show that the scheme meets the security requirements of privacy protection and key management in epidemiological survey.

Preparation and Evaluation of Pectin-based Colon-specific Pulsatile Capsule In Vitro and In Vivo

Jing Liu,Liang-ke Zhang,Yuntao Jia,Wenjing Hu,Jing-qing Zhang,Huiming Jiang 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.11

The purpose of this study was to develop and evaluate a colon-specific, pulsatile drug delivery system, which consists of an impermeable capsule body filled with a 5-aminosalicylic acid rapid-disintegrating tablet and a pectin-based erodible plug placed in the opening of the capsule body. To obtain an appropriate gel-forming ability and suitable lag time for the colon-specific drug delivery, high-methoxy pectin (HM-pectin) was formulated with lactose and lowmethoxy pectin (LM-pectin) with HPMC to prepare the plug tablet. In order to evaluate the lag time, prior to the rapid drug release, both the formulation of the plug tablet and in vitro release medium were studied. The lag time prior to the rapid drug release was mainly determined by the HM-pectin/lactose or LM-pectin/HPMC ratio. The addition of pectinase or rat cecal content into the release medium shortened the lag time significantly, which predicted the probable enzyme sensitivity of pectin plug tablet. In vivo studies showed that the plasma concentration of drug can only be detected 6 h after oral administration of the pulsatile capsule, which indirectly proved the colon-specific characteristics. These results show that the pulsatile capsule may have the therapeutic action for colon-specific drug delivery.

Weighting factor design based on SVR–MOPSO for finite set MPC operated power electronic converters

Yonglu Liu,Zhengmao Yang,Xubin Liu,Hanbing Dan,Wenjing Xiong,Tao Ling,Mei Su 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.7

Selecting weighting factors is a challenge for the finite set model predictive control (FS-MPC). Based on the support vector regression (SVR) algorithm and the multi-objective particle swarm optimization (MOPSO) algorithm, this paper proposes a new weighting factor design principle. SVR is used to establish the functional relationship between the input weighting factors and the output performance indexes (such as the average switching frequency (fsw) and the total harmonic distortion of the output voltage). Even in the case of small samples, this can provide accurate performance index estimates for any combination of weighting factors. The established SVR function is taken as the fitness function. Then, MOPSO is used to search for Pareto optimal weighting factor combinations. The proposed method can converge in a few steps and does not require tedious calculations. Moreover, it is applicable to optimization problem with two or more weighting factors for arbitrary topology models. It also provides a range of optimal weighting factor solution sets. Finally, the proposed methodology is verified on a practical weighting factor design problem in a FS-MPC regulated voltage source inverter. Experimental results confirm the correctness of the theoretical analysis.

Expression of fox-related genes in the skin follicles of Inner Mongolia cashmere goat

Wenjing Han,Xiaoyan Li,Lele Wang,Honghao Wang,Kun Yang,Zhixin Wang,Ruijun Wang,Rui Su,Zhihong Liu,Yanhong Zhao,Yanjun Zhang,Jinquan Li 아세아·태평양축산학회 2018 Animal Bioscience Vol.31 No.3

Objective: This study investigated the expression of genes in cashmere goats at different periods of their fetal development. Methods: Bioinformatics analysis was used to evaluate data obtained by transcriptome sequencing of fetus skin samples collected from Inner Mongolia cashmere goats on days 45, 55, and 65 of fetal age. Results: We found that FoxN1, FoxE1, and FoxI3 genes of the Fox gene family were probably involved in the growth and development of the follicle and the formation of hair, which is consistent with previous findings. Real-time quantitative polymerase chain reaction detecting system and Western blot analysis were employed to study the relative differentially expressed genes FoxN1, FoxE1, and FoxI3 in the body skin of cashmere goat fetuses and adult individuals. Conclusion: This study provided new fundamental information for further investigation of the genes related to follicle development and exploration of their roles in hair follicle initiation, growth, and development.

Tensile-Mechanical Degradation-Properties and J-C Constitutive Model of Studs after Strong-Acid Corrosion

Wenjing Qiao,Hao Zhang,Gang Zhang,Fan Yang,Zhiguo Liu 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.9

This paper presents an investigation on strong-acid relations between corrosion rate and corrosion time in 30 studs, dipped into 36% industrial hydrochloric acid through 0.5 h, 1 h, 2 h, 4 h, 8 h, 12 h, 24 h, 48 h, and 72 h, respectively. These corroded studs are performed tensile tests to study failure mode and stress-strain curves in studs with different corrosion time. Thereafter, a 3-D finite element is established through computer program to validate test results, and then analyze mechanical properties along with failure mode of studs exposed to strong-acid corrosion. The analysis results show that the failure mode gradually changes from ductile-damage state to brittle-damage state. The corrosion rates present a non-linear elevation with an increase of strong-acid-corrosion time. The nominal yield strength, the nominal ultimate strength, and the elongation in the corroded studs exhibit a fast-downward trend when increasing corrosion time. However, the degradation of elastic modulus turn into a slow step and the yield strength ratio in studs tends to be steady. The J-C model (Johnson-Cook Constitutive) with updated coefficients can be applied to reflect the constitutive relations in studs after strong-acid corrosion under quasi-static tension conditions. Further, this model can simulate stress flows within studs after strong-acid corrosion. This research results can provide a guide for long-lifetime construction and safe maintenance in steel structural bridge.

Political Ties and Firm Performance in China: Evidence from a Quantile Regression

Wenjing Xie,Keji Liu,Fei Xie,Haoyuan Ding 동아시아연구원 2017 Journal of East Asian Studies Vol.17 No.3

Whether political ties enhance or weaken firm performance has been widely investigated in a number of studies, including some on China. Based on a database of non-financial A-share listed firms from 2004 to 2012, we study the effects of political ties on firm performance within a quantile regression framework. We find that there is a positive relationship between political ties and economic performance, but that it is diminishing with respect to firm performance. Political ties appear particularly important for weaker firms.

Development of EST-SSRs from the ark shell (Scapharca broughtonii) transcriptome and their application in genetic analysis of four populations

Wenjing Wang,Biao Wu,Zhihong Liu,Liqing Zhou,Xiujun Sun,Jiteng Tian,Aiguo Yang 한국유전학회 2021 Genes & Genomics Vol.43 No.6

Background The ark shell (Scapharca broughtonii) is one of the most economically important mollusks in the Bohai Sea and Yellow Sea of China. In recent years, ark shells from the Korean population were introduced to China for seed propagation and culture. Objective To explore the impact of the introduction of Korean ark shell on the genetic diversity of native population in China. Methods Simple sequence repeat (SSR) is efective and widely used tool for genetic analysis. In this study, 180 EST-SSRs were selected and verifed by polymerase chain reaction and polyacrylamide gel electrophoresis. Subsequently, fve polymorphic EST-SSRs were screened and their primers were modifed by fuorescein for use in the genetic analysis of four populations. Results Genetic analysis showed that 361 alleles amplifed by fve SSR loci were detected in the four populations. The number of alleles for the fve SSRs ranged from 8 to 30, with a mean of 18.05 (standard deviation, SD=6.492). The efective number of alleles varied from 2.253 to 22.222, with a mean of 10.596 (SD=4.713). Observed heterozygosity and expected heterozygosity were 0.167–0.833 and 0.566–0.971, with average values of 0.520 (SD=0.177) and 0.891 (SD =0.062), respectively. Polymorphic information content ranged from 0.521 to 0.953, with a mean of 0.865 (SD=0.070). The pairwise genetic diferentiation coefcient (FST) of the four populations ranged from 0.0267 to 0.0477, showing low genetic diferentiation. The phylogenetic tree constructed by neighbor-joining method showed that the genetic distance between the Chinese Dalian native population and three Korean populations was relatively more far than that among those Korean populations. Conclusion The results indicated that the genetic structure of the Dalian wild population was less afected by the introduced Korean wild populations.

Regional Economic Evaluation Based on a Novel Fuzzy Clustering Method in Big data

Liu Zhaohui,Li Liyan,Xu Wenjing 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.3

Selenide-linked polydopamine-reinforced hybrid hydrogels with on-demand degradation and light-triggered nanozyme release for diabetic wound healing

Wenjing Li,Ying Bei,Xiangqiang Pan,Jian Zhu,Zhengbiao Zhang,Tinglin Zhang,Jieting Liu,Dan Wu,Meng Li,Yan Wu,Jie Gao 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Multifunctional hydrogels with controllable degradation and drug release have attracted extensive attention in diabetic wound healing. This study focused on the acceleration of diabetic wound healing with selenidelinked polydopamine-reinforced hybrid hydrogels with on-demand degradation and light-triggered nanozyme release. Methods Herein, selenium-containing hybrid hydrogels, defined as DSeP@PB, were fabricated via the reinforcement of selenol-end capping polyethylene glycol (PEG) hydrogels by polydopamine nanoparticles (PDANPs) and Prussian blue nanozymes in a one-pot approach in the absence of any other chemical additive or organic solvent based on diselenide and selenide bonding-guided crosslinking, making them accessible for large-scale mass production. Results Reinforcement by PDANPs greatly increases the mechanical properties of the hydrogels, realizing excellent injectability and flexible mechanical properties for DSeP@PB. Dynamic diselenide introduction endowed the hydrogels with on-demand degradation under reducing or oxidizing conditions and light-triggered nanozyme release. The bioactivity of Prussian blue nanozymes afforded the hydrogels with efficient antibacterial, ROS-scavenging and immunomodulatory effects, which protected cells from oxidative damage and reduced inflammation. Further animal studies indicated that DSeP@PB under red light irradiation showed the most efficient wound healing activity by stimulating angiogenesis and collagen deposition and inhibiting inflammation. Conclusion The combined merits of DSeP@PB (on-demand degradation, light-triggered release, flexible mechanical robustness, antibacterial, ROS-scavenging and immunomodulatory capacities) enable its high potential as a new hydrogel dressing that can be harnessed for safe and efficient therapeutics for diabetic wound healing.

The experimental investigation of bisphenol A degradation by Fenton process with different types of cyclodextrins

Wenjing Chen,Changjun Zou,Yuan Liu,Xiaoke Li 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.56 No.-

In this work, the degradation efficiencies of bisphenol A (BPA) by Fenton reaction were comparedsystematically with varying cyclodextrins. The results showed that the removal rate of BPA displays aconsiderable increase by Fenton reaction in presence of b-cyclodextrin (b-CD) and its derivatives. Specifically, 98 2% and 89 2% of BPA was removed with carboxymethyl-b-cyclodextrin (CMCD) andb-CD, respectively. Additionally, to understand the reaction mechanism, the structure activity ofcyclodextrins with substrate and the kinetic of Fenton reaction with cyclodextrins have beeninvestigated. Results showed that the structure activity was the major role for cyclodextrins in thissystem.