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      • SCIESCOPUSKCI등재

        TCA: A Trusted Collaborative Anonymity Construction Scheme for Location Privacy Protection in VANETs

        Zhang, Wenbo,Chen, Lin,Su, Hengtao,Wang, Yin,Feng, Jingyu Korean Society for Internet Information 2022 KSII Transactions on Internet and Information Syst Vol.16 No.10

        As location-based services (LBS) are widely used in vehicular ad-hoc networks (VANETs), location privacy has become an utmost concern. Spatial cloaking is a popular location privacy protection approach, which uses a cloaking area containing k-1 collaborative vehicles (CVs) to replace the real location of the requested vehicle (RV). However, all CVs are assumed as honest in k-anonymity, and thus giving opportunities for dishonest CVs to submit false location information during the cloaking area construction. Attackers could exploit dishonest CVs' false location information to speculate the real location of RV. To suppress this threat, an edge-assisted Trusted Collaborative Anonymity construction scheme called TCA is proposed with trust mechanism. From the design idea of trusted observations within variable radius r, the trust value is not only utilized to select honest CVs to construct a cloaking area by restricting r's search range but also used to verify false location information from dishonest CVs. In order to obtain the variable radius r of searching CVs, a multiple linear regression model is established based on the privacy level and service quality of RV. By using the above approaches, the trust relationship among vehicles can be predicted, and the most suitable CVs can be selected according to RV's preference, so as to construct the trusted cloaking area. Moreover, to deal with the massive trust value calculation brought by large quantities of LBS requests, edge computing is employed during the trust evaluation. The performance analysis indicates that the malicious response of TCA is only 22% of the collaborative anonymity construction scheme without trust mechanism, and the location privacy leakage is about 32% of the traditional Enhanced Location Privacy Preserving (ELPP) scheme.

      • KCI등재

        Dapk1 promoted inflammation of infantile pneumonia by p38MAPK/NF-κB signaling pathway

        Zhang Wenbo 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.3

        Background The present study was designed to investigate the function of death-associated protein kinase 1 (DAPK1) in infantile pneumonia and explore the potential mechanism of the actions. Objective Male C57BL/6 mice were injected with 2 mg/kg of LPS for the mice model of infantile pneumonia. A549 cells were treated with 100 ng/ml of LPS for vitro model of infantile pneumonia. Dapk1 mRNA and protein expressions in 6, 12 or 24 h after induction model of mice. Results Dapk1 gene increased inflammation in vitro model through activation of p38MAPK-mediated NF-κB expression. The inhibition of p38MAPK or NF-κB reduced the pro-inflammation effects of DAPK1 in infantile pneumonia. Conclusions Our study demonstrates that Dapk1 promoted inflammation of infantile pneumonia by p38MAPK/NF-κB signaling pathway, may be achieved inflammation by activation of p38MAPK/NF-κB signaling pathway.

      • KCI등재

        Performance investigation of nanoscale thermal cloak by the perforated silicon film

        Zhang Jian,Zhang Haochun,Zhang Dong,Sun Wenbo,Li Yiyi 한국물리학회 2022 Current Applied Physics Vol.35 No.-

        In recent years, nanoscale thermal cloak, as a representative of nanoscale heat flux regulation devices, has attracted a lot of attention from researchers. However, the existing design methods are relatively complicated and all adopt constant temperature boundaries, the temperature changes constantly in the real environment, which greatly hinders its engineering applications. In this paper, inspired by phonon localization theory, we construct a nanoscale thermal cloak by a perforated silicon membrane and evaluate its cloaking performance and dynamic response. Results show that when the perforated area is fixed, the more the number of holes, the better the cloaking performance. In addition, the nanoscale thermal cloak still exhibits good cloaking performance in the dynamic environment. Finally, the cloaking mechanism is analyzed by calculating the phonon density of states (PDOS) and mode participation rate (MPR), and the reduction of thermal conductivity in the functional region is attributed to phonon localization.

      • Research on the Surface Defect Detection of Magnetic Sheet for Industrial Manufacture

        Wenbo Zhang,Rongwei Duan,Yongxin Feng,Deyu Zhang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.1

        The research of defect detection technology of magnetic sheet surface has important significance for improvement of production efficiency and product quality in enterprise. A single threshold method is used for binary segmentation of magnetic sheet image in this paper, then the template localization algorithm is used for template position of magnetic sheet image after binary segmentation, the magnetic sheet image with different position should be transformed into a unified coordinate system for detecting, then least square method is used for fitting straight line and fillet edge, then the calculated values are compared with standard value to determine whether are knock edges. Further, the appropriate grayscale threshold is set by the pitting and scratches characteristics of magnetic sheet image, the magnetic sheet image should be segmented according to the determined threshold value, if the defect exists, the defect area or length will be calculated, then the result is compared with standard values to determine whether is pitting or scratches. The final tests of technology in this paper show that the detection rate of knock edge and the detection rate of pitting or scratches are both acceptable.

      • KCI등재

        Study on pharmacokinetics and tissue distribution of single dose oral tryptanthrin in Kunming mice by validated reversed-phase high-performance liquid chromatography with ultraviolet detection

        Xiaoyan Zhang,Jie Xia,Wenjing Zhang,Yao Luo,Wenbo Sun,Wei Zhou 한국한의학연구원 2017 Integrative Medicine Research Vol.6 No.3

        Background: Tryptanthrin is a major active constituent of several Chinese herbal plants, such as Isatidis radix. Tryptanthrin had been demonstrated to have several beneficial pharmacological effects in vitro for human diseases, including antitumor, anti-inflammatory and antibacteria activities. In contrast to the extensive in vitro investigations, the in vivo disposition process of tryptanthrin was explored limitedly. Methods: In this study, the pharmacokinetics (PK) and tissue distribution of tryptanthrin in Kunming mice following a single oral dose of 80 mg/kg tryptanthrin were investigated for the first time. Mouse plasma, liver, heart, spleen, lung, kidney and brain were collected and analyzed using a validated reversed-phase high-performance liquid chromatography with ultraviolet detection (RP-HPLC–UV) method after biological sample preparation by a simple liquid–liquid extraction. Results: The chromatographic analysis was performed on a Diamonsil C18 column (5 μm, 250 mm × 4.6 mm) and ultraviolet detection was set at a wavelength of 251 nm. The analysis was achieved with a mobile phase of methanol (A) and water (B) (60:40, v/v) at a flow rate of 1.0 mL/min. The method was linear over the concentration range of 4.0–400.0 μg/mL with a lower limit of quantification of 0.10–0.30 μg/mL. Inter- and intraday precisions (relative standard deviations %) were all within 2.93%. Recoveries of tryptanthrin were more than 86.44%. Maximal tryptanthrin concentrations in plasma and tissues of mice were reached within 2.5 hours. The actual highest concentration (Cmax) in mouse plasma was 3.13 μg/mL, the area under the curve (AUC0–t) was 9.38 h μg/mL, and the terminal half-life was 2.27 hours. The volume of distribution was 343.89 mL, the clearance rate was 204.58 mL/h, and the PK of tryptanthrin in mice after oral administration was fit to 2 compartment 1 st Order. After oral dosing of tryptanthrin to Kunming mice, the analyte was well distributed to the plasma and main tissues. Cmax was found in the liver with a mean value of 3.54 μg/g, followed by that in the kidney, lung, spleen, heart, and brain. Conclusion: In this study, a validated RP-HPLC–UV method was developed and successfully applied to PK and tissue distribution of oral tryptanthrin in mice. We confirmed that tryptanthrin was closely related and targeted to plasma, liver, kidney, and lung. These results indicate that tryptanthrin will have a good clinical application in the liver, kidney, or lung. The clinical use of tryptanthrin should focus on its pharmacodynamics and safety study in these tissues.

      • KCI등재

        Monitoring for Damage in Two-Dimensional Pre-Stress Scratching of SiC Ceramics

        Gaofeng Zhang,Yijiang Zeng,Wenbo Zhang,Houming Zhou,Zhangya Wen,Yuan Yao 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.11

        This paper reports an approach to use the acoustic emission (AE) technology for monitoring the surface/subsurface damage in twodimensional pre-stress scratching of SiC ceramics, in which the two-dimensional pre-stress is used to decrease the scratch-induced damage. Experiments in this study were conducted on a UMT-2 machine (CETR USA) utilizing a designed pre-stressing device under pressures of 0 MPa, 300 MPa and 500 MPa. The experimental results demonstrate that average frequency and magnitude of AE signals have a good correlation with the scratching tangential force and the scratch-induced surface /subsurface damage of materials. For a given normal load, the average frequency and magnitude of AE signals are observed to decrease with the increase in pre-stress, which indicates that surface/subsurface damage of SiC ceramics induced by two-dimensional pre-stress scratching is less than that induced by conventional scratching. The findings provide fundamental information for developing a practical on-line AE monitoring system that is effective in detecting surface/subsurface damage in scratching or grinding of ceramics. These results also demonstrate that two-dimensional pre-stress method contributes to decreasing the machining damage of brittle materials.

      • KCI등재

        Energy Efficient Hybrid Satellite Terrestrial 5G Networks with Software Defined Features

        Jiaxin Zhang,Xing Zhang,Muhammad Ali Imran,Barry G. Evans,Yan Zhang,Wenbo Wang 한국통신학회 2017 Journal of communications and networks Vol.19 No.2

        In order to improve the manageability and adaptabilityof future 5G wireless networks, the software orchestration mechanism,named software defined networking (SDN) with controland user plane (C/U-plane) decoupling, has become one of themost promising key techniques. Based on these features, the hybridsatellite terrestrial network is expected to support flexibleand customized resource scheduling for both massive machinetype-communication (MTC) and high-quality multimedia requestswhile achieving broader global coverage, larger capacity and lowerpower consumption. In this paper, an end-to-end hybrid satelliteterrestrial network is proposed and the performance metrics, e. g., coverage probability, spectral and energy efficiency (SE andEE), are analysed in both sparse networks and ultra-dense networks. The fundamental relationship between SE and EE is investigated,considering the overhead costs, fronthaul of the gateway(GW), density of small cells (SCs) and multiple quality-ofservice(QoS) requirements. Numerical results show that comparedwith current LTE networks, the hybrid system with C/U split canachieve approximately 40% and 80% EE improvement in sparseand ultra-dense networks respectively, and greatly enhance thecoverage. Various resource management schemes, bandwidth allocationmethods, and on-off approaches are compared, and theapplications of the satellite in future 5G networks with softwaredefined features are proposed.

      • Research and Implement on Intelligent Scheduling of Coal Ash Delivering

        Na Zhang,Yuyan Zhang,Wenbo Yu,Libo Xu 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.6

        The coal ash sales process in our country is cumbersome, inefficient, lack of effective management and vehicle guidance policy, which leads to frequent traffic jams, ash loss, monitoring difficult and other issues, this paper presents a valid intelligent scheduling strategy for coal ash shipping to design and implement a new coal ash sales system, which proposes a good solution to the problem of coal ash vehicle indiscriminate disorderly, chaotic management

      • KCI등재

        Photocatalytic oxidation of gas-phase Hg0 by carbon spheres supported visible-light-driven CuO–TiO2

        Jiang Wu,Chaoen Li,Xiantuo Chen,Jing Zhang,Lili Zhao,Tianfang Huang,Tao Hu,Chong Zhang,Bu Ni,Xiao Zhou,Pankun Liang,Wenbo Zhang 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.46 No.-

        A simplified approach for the fabrication of CuO/TiO2@C is demonstrated. In this study, low cost CuO/TiO2@C photocatalysts (CSs loading 0.25–2 wt.%) were prepared, characterized and evaluated for gasphaseHg0 oxidation. The obtained CuO/TiO2@C photocatalysts were used to remove gaseous elementalmercury under UV light and LED respectively, and the optimum doping of content of CSs was determined. The results showed that the CuO/TiO2@C photocatalysts were highly efficient in oxidizing Hg0, reachingabove 64% when the CSs doping reached 0.5 wt.%. We have proposed that the probable mechanism bywhich CuO/TiO2@C photocatalysts remove gaseous elemental mercury: with CSs doping, CSs can act assensitizer and transfer electrons to the semiconductors, triggering the formation of very reactive radicalsto improve photocatalytic efficiency.

      • KCI등재

        Kidney bean defense response induced by western flower thrips, Frankliniella occidentalis feeding and the attenuated effect of calcium ion chelator

        Zhang Tao,Zhi Junrui,Liu Yong,Yue Wenbo,Zeng Guang 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2

        Calcium ion (Ca 2+ ) plays an important role in plant–insect interactions. Ethylene glycol-bis(2-aminoethylether)-N, N, N ′ , N ′ -tetraacetic acid (EGTA), a Ca 2+ chelator, can abolish Ca 2+ in plant cells following the disruption of plant physiological processes and the plant’s defense responses against biotic stress. To clarify whether EGTA pretreatment plants have an inhibitory effect on insect feeding induction, we determined variations in kidney bean (Phaseolus vulgaris (L., Fabales: Fabaceae)) plant defense responses induced by western flower thrips (WFT) (Frankliniella occidentalis (Pergande)) feeding and the reversal effects of EGTA. The results showed that WFT feeding can significantly activate the expression level of the jasmonic acid (JA) pathway marker genes allene oxide synthase (AOS) and lipoxygenase (LOX) and salicylic acid (SA) pathway marker genes phenylalanine ammonia lyase (PAL) and β-1,3 glucanase (PR-2), and induce the biosynthesis of JA and SA. However, pre treatment with EGTA showed varying degrees of reversal effects on JA and SA content and related gene expression levels with WFT feeding. These results indicate that WFT feeding can induce the biosynthesis of JA and SA and the expression of related genes to enhance the defense responses in kidney beans plants, while pretreatment with EGTA can attenuate the WFT-induced defense responses.

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