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      • KCI등재

        Scale up of xylitol production from sugarcane bagasse hemicellulosic hydrolysate by Candida guilliermondii FTI 20037

        Priscila Vaz de Arruda,Júlio César dos Santos,Rita de Cássia Lacerda Brambilla Rodrigues,Débora Danielle Virgínio da Silva,Celina Kiyomi Yamakawa,George Jackson de Moraes Rocha,Jonas Nolasco Júnior,Jo 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.47 No.-

        In this study, volumetric oxygen mass transfer coefficient (kLa) was selected as a criterion for facilitatingthe scale up of xylitol production by Candida guilliermondii at the bench and pilot-scale level. A kLa valueof 16 h 1 was applied in reactors with volumetric capacity of 2.4 L, 18 L and 125 L. Fermentation wassuccessfully scaled-up from the bench to pilot-scale level with all experiments demonstrating aminimum of 60% xylose to xylitol conversion efficiency. Under all evaluated conditions glycerol andethanol were also produced as by-products of xylose metabolism. Only minor differences were observedin the fermentation profile when reactor volumes ranging from 2.4 L to 125 L were used forexperimentation purposes, reaching, at pilot scale, yield and volumetric productivity of 0.55 g g 1and 0.31 g L 1 h 1, respectively, with maximum specific growth rate of 0.26 h 1. This demonstrates andreinforces the feasibility of using kLa as scale up criterion. The use of this parameter allowed precisereproduction of results obtained at bench bioreactor level to a larger scale; this is extremely crucial andimportant information considering that the aim of the proposed biotechnological process is to reach thelevel required for the industrial viability.

      • KCI등재

        Estimating the Pragmatic Language Abilities in Indian Adolescents between 10 and 16 Years of Age: Using Contextually Flooded Visual Scenes

        Larisa Vaz,Sudhin Karuppali 한국언어청각임상학회 2019 Communication Sciences and Disorders Vol.24 No.3

        배경 및 목적: 청소년의 화용언어 평가는 이들이 주로 접하는 학업이나 기타 다른 의사소통 맥락을 사용한다. 지금까지 인도에서는 화용언어 평가에 대한 관심이 적었기에 본 연구는 독창적인 시각자료를 사용하여 정상발달을 보이는 청소년의 맥락 관련 화용능력 프로파일을 제공하고자 하였다. 방법: 본 연구의 참여자는 10-16세 청소년이었으며 1년 간격의 여섯 연령집단으로 구분되었다. 본 연구에서는 물리적 상황 맥락(PCS), 물리적 사건 맥락(PCE), 청자 관계(AR), 청자 수(AN), 청자 감정상태(AM), 종합적 맥락(CT) 등으로 맥락 관련 변수를 측정하였다. 본 연구는 세 단계로 실시되었다. 첫 단계는 자극 개발 단계(자극 준비, 내용 타당성, 예비연구)이었으며, 두 번째 단계는 과제실행 단계, 세 번째 단계는 자료 및 통계분석 단계이었다. 결과: 본 연구에서는 PCS, PCE, AR, AN, AM, CT 점수를 연령에 따라 비교하였다. 크루스칼 왈리스 테스트 결과, 총 여섯 변수 모두에서 연령에 따른 차이가 통계적으로 유의하였다(p<.05). 만-휘트니 테스트 결과, 일부 연령집단에서는 통계적으로 유의한 차이가 관찰되지 않았으나(p>.05) 인지발달에 따른 일부 연령집단(10-11세, 12-14세, 15세)에서는 통계적으로 유의한 차이가 관찰되었다(p<.05). 논의 및 결론: 본 연구는 인도 아동의 정상 화용발달 단계를 이해하는 데 도움이 될 수 있는 새로운 평가도구를 제시하였으며 이를 통해 언어발달장애가 있는 청소년 평가에 도움을 줄 수 있을 것이다. Objectives: The assessment of pragmatic language in adolescents mainly focuses on using academic and other communicative contexts that they are largely exposed to. Considering the lesser focus laid on aspects of pragmatic language in India, the current study aims to profile the context-related pragmatic language abilities in typically developing adolescents using ingenious visual-based scenes. Methods: The participants were 10- to 16-year-old allocated into six age groups with 1-year intervals. The targeted context-related parameters were physical context-setting (PCS), physical context-event (PCE), audience relationship (AR), audience number (AN), audience mood (AM), and context total (CT). The study was carried out in three phases. Phase I included the development of the stimuli (stimuli preparation, content validation, and pilot study); Phase II involved the task administration; while, Phase III involved the data and statistical analysis. Results: The results have been discussed based on the age-wise comparisons of the total scores received in PCS, PCE, AR, AN, AM, and CT. The results of the Kruskal-Wallis test indicated an overall good level of significance (p<.05) across the 6 groups for all six parameters. Though Mann Whitney Tests indicated a poor level of significance (p>.05) between certain groups across certain parameters, a good level of significance (p<.05) was obtained when viewing the groups from a cognitive perspective (10-11, 12-14, and 15 years). Conclusion: This study delivers a novel tool in understanding pragmatic developmental trends in Indian children, laying new paths towards the assessment of adolescents with language disorders.

      • SCOPUSKCI등재

        More frequent detection of calcified carotid atherosclerotic plaques and mineralized laryngeal cartilages on digital than on film-based panoramic radiographs

        de-Azevedo-Vaz, Sergio Lins,Machado, Joao Victor Pereira,Pereira, Teresa Cristina Rangel,Freitas, Deborah Queiroz Korean Academy of Oral and Maxillofacial Radiology 2019 Imaging Science in Dentistry Vol.49 No.1

        Purpose: To determine whether calcified carotid atherosclerotic plaques(CCAPs) and mineralized laryngeal cartilages (MLCs) were more frequently detected on digital or film-based panoramic radiographs. The clinical relevance of this question is that some radiopacities seen on digital radiographs may correspond to medium-density tissues that are not necessarily mineralized. Materials and Methods: Data were collected from panoramic radiographs and the respective reports issued by 2 private oral radiology centers. A total of 388 radiographs and reports were divided into film-based (group A) and digital (group D) radiographs. The frequencies of CCAPs and MLCs were analyzed using the Fisher exact test, and odds ratios were also calculated (${\alpha}=1%$). Results: The mean age of patients whose reports and radiographs showed CCAPs and/or MLCs ranged from 50.1 to 54.1 years. There was a predominance of females. A higher frequency of CCAPs and MLCs was observed in group D than in group A at both centers(P<0.01). CCAPs and MLCs were detected 4 times more frequently in group D than in group A at one of the centers. Conclusion: CCAPs and MLCs were more frequently detected on digital than on film-based panoramic radiographs. Further studies are needed to determine whether such radiopacities do indeed correspond to mineralized, rather than medium-density, tissues.

      • SCIESCOPUSKCI등재

        The MAK16 Gene of Entamoeba histolytica and Its Identification in Isolates from Patients

        Maria del Pilar Crisostomo-Vaz,Victor Alberto Marevelez-Acost,Andres Flores-Luna,Enedina Jimenez-Cardoso 대한기생충학열대의학회 2014 The Korean Journal of Parasitology Vol.52 No.4

        To identify sequences of Entamoeba histolytica associated with the development of amebic liver abscess (ALA) in hamsters, subtractive hybridization of cDNA from E. histolytica HM-1:IMSS under 2 growth conditions was performed: 1) cultured in axenic medium and 2) isolated from experimental ALA in hamsters. For this procedure, 6 sequences were obtained. Of these sequences, the mak16 gene was selected for amplification in 29 cultures of E. histolytica isolated from the feces of 10 patients with intestinal symptoms and 19 asymptomatic patients. Only 5 of the 10 isolates obtained from symptomatic patients developed ALA and amplified the mak16 gene, whereas the 19 isolates from asymptomatic patients did not amplify the mak16 gene nor did they develop ALA. Based on the results of Fisher’s exact test (P<0.001), an association was inferred between the presence of the mak16 gene of E. histolytica and the ability to develop ALA in hamsters and with the patient’s symptoms (P=0.02). The amplification of the mak16 gene suggests that it is an important gene in E. histolytica because it was present in the isolates from hamsters that developed liver damage.

      • KCI등재

        More frequent detection of calcified carotid atherosclerotic plaques and mineralized laryngeal cartilages on digital than on film-based panoramic radiographs

        Sergio Lins de-Azevedo-Vaz,João Victor Pereira Machado,Teresa Cristina Rangel Pereira,Deborah Queiroz Freitas 대한영상치의학회 2019 Imaging Science in Dentistry Vol.49 No.1

        Purpose: To determine whether calcified carotid atherosclerotic plaques (CCAPs) and mineralized laryngeal cartilages (MLCs) were more frequently detected on digital or film-based panoramic radiographs. The clinical relevance of this question is that some radiopacities seen on digital radiographs may correspond to medium-density tissues that are not necessarily mineralized. Materials and Methods: Data were collected from panoramic radiographs and the respective reports issued by 2 private oral radiology centers. A total of 388 radiographs and reports were divided into film-based (group A) and digital (group D) radiographs. The frequencies of CCAPs and MLCs were analyzed using the Fisher exact test, and odds ratios were also calculated (α=1%). Results: The mean age of patients whose reports and radiographs showed CCAPs and/or MLCs ranged from 50.1 to 54.1 years. There was a predominance of females. A higher frequency of CCAPs and MLCs was observed in group D than in group A at both centers (P<0.01). CCAPs and MLCs were detected 4 times more frequently in group D than in group A at one of the centers. Conclusion: CCAPs and MLCs were more frequently detected on digital than on film-based panoramic radiographs. Further studies are needed to determine whether such radiopacities do indeed correspond to mineralized, rather than medium-density, tissues.

      • Need for and Relevance of Customer Relationship Management in Engineering Colleges

        Nancy D'Costa Vaz 아시아기술혁신학회 2014 Asian Journal of Innovation and Policy Vol.3 No.2

        Modern education, with special reference to higher education (HE), is far taken out of the traditional meaning of education. A number of business features have infiltrated these institutions of HE where students assume the place of a customer. In the present business scenario customer relationship management (CRM) technology assumes an important role in managing customers. Therefore a relevant question would be to know whether educational institutions need to implement this technology to manage their constituent relationships. This paper makes an attempt to evaluate studies on commercial features of a modern educational system and then present the findings of a study conducted to know the relevance of CRM Technology in HE. An evaluation is also made to know the awareness of the concept of CRM among the educators. The findings show that the educators’ awareness of CRM strategies is good, of CRM concepts is poor and of practice is average. Further, an overwhelming majority of the respondents felt that CRM is relevant for educational institutions in the present scenario.

      • KCI등재

        Need for and Relevance of Customer Relationship Management in Engineering Colleges

        Nancy, D'Costa nee Vaz Asian Society for Innovation and Policy 2014 Asian Journal of Innovation and Policy Vol.3 No.2

        Modern education, with special reference to higher education (HE), is far taken out of the traditional meaning of education. A number of business features have infiltrated these institutions of HE where students assume the place of a customer. In the present business scenario customer relationship management (CRM) technology assumes an important role in managing customers. Therefore a relevant question would be to know whether educational institutions need to implement this technology to manage their constituent relationships. This paper makes an attempt to evaluate studies on commercial features of a modern educational system and then present the findings of a study conducted to know the relevance of CRM Technology in HE. An evaluation is also made to know the awareness of the concept of CRM among the educators. The findings show that the educators' awareness of CRM strategies is good, of CRM concepts is poor and of practice is average. Further, an overwhelming majority of the respondents felt that CRM is relevant for educational institutions in the present scenario.

      • SCOPUSKCI등재

        STABLE WEAK SHADOWABLE SYMPLECTOMORPHISMS ARE PARTIALLY HYPERBOLIC

        Bessa, Mario,Vaz, Sandra Korean Mathematical Society 2014 대한수학회논문집 Vol.29 No.2

        Let M be a closed, symplectic connected Riemannian manifold and f a symplectomorphism on M. We prove that if f is $C^1$-stably weak shadowable on M, then the whole manifold M admits a partially hyperbolic splitting.

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