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유형식,한두석,엄인웅,김수남 원광대학교 치의학연구소 1993 圓光齒醫學 Vol.3 No.1
The purpose of this study was to evalutate the primary lesions of the jaws in 110 patients of receiving treatment in Department of Oral and Maxillofacial Surgery, Wonkwang University. On the basis of patients record, retrospective examination was performed in terms of diagnosis, treatment, and classifications. According to the age and sex, the frequency on location, signs and symptoms, duration of Hospital visit after onset, and radiologic features were studied. The results obtained were as follows 1. The most common disease of the bone lesions were infectious disease. 2. The ratio of male and female patients was 1.4 : 1. 3. Most of the cases occured in the age 30 to 59. 4. Chief complaints at the visit were swelling, followed by pain, pus discharde and others. 5. Interval of Hospital visit after onset was within 30 days. 6. The size of the lesions were in the category of over 40㎜ diameter. 7. The incidence of mandible were similar to that of the maxilla.
Balanced approach can help initial outcomes
Dong-Sik Kim,Young-Dong Yu,Sung-Won Jung,Kyung-Sook Yang,Yeon-Seok Seo,Soon-Ho Um,Sung-Ock Suh 대한외과학회 2014 Annals of Surgical Treatment and Research(ASRT) Vol.87 No.1
Purpose: To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors. Methods: Medical records of initial 50 liver transplantations were reviewed retrospectively. Results: Twenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 ± 11.6 and 13.1 ± 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8 %, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT. Conclusion: As a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.
Kim, Dong-Sik,Yu, Young-Dong,Jung, Sung-Won,Yang, Kyung-Sook,Seo, Yeon-Seok,Um, Soon-Ho,Suh, Sung-Ock The Korean Surgical Society 2014 Annals of Surgical Treatment and Research(ASRT) Vol.87 No.1
<P><B>Purpose</B></P><P>To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors.</P><P><B>Methods</B></P><P>Medical records of initial 50 liver transplantations were reviewed retrospectively.</P><P><B>Results</B></P><P>Twenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 ± 11.6 and 13.1 ± 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8%, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT.</P><P><B>Conclusion</B></P><P>As a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.</P>
유연호(Yeun-Ho Yu),민경식(Kyeong-Sik Min),남원상(Won-Sang Nam),변준형(Joon-Hyung Byun),엄문광(Moon-Kwang Um) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.6
The soundness of composite materials has been tested by nondestructive methods such as X-ray, C-scan, AE (Acoustic Emission), etc. but these testings are not suitable for composite structures in operation. Recently, optical fiber sensors are widely used for monitoring of curing, distortion, and damage of composite materials. When optical fiber sensors are embedded in composite materials, however, they can affect mechanical properties because of the langer diameter of sensors compared to reinforcing fibers. In this study, effects of embedded optical fiber sensors on mechanical properties of composite materials are identified. The result of tensile, compression and flexural properties in both cases of with and without optical fibers are reported.
재발한 혼합 간세포 담관상피암종 및 저혈관성 간세포암종 동시 절제 1예
김태형 ( Tae Hyung Kim ),엄순호 ( Soon Ho Um ),박상정 ( Sang Jung Park ),박승운 ( Seung Woon Park ),이한아 ( Han Ah Lee ),서연석 ( Yeon Seok Seo ),유영동 ( Young Dong Yu ),김동식 ( Dong-sik Kim ),김주영 ( Joo Young Kim ) 대한간암학회 2017 대한간암학회지 Vol.17 No.1
Liver cancer is more complex to treat compared to cancers in other organs, since liver function should be considered. In addition, only a few patients can be applied curative treatment due to advanced stage at diagnosis. Therefore, early stage detection is important and has been increased through screening and surveillance programs using image modalities recently. However, it is still difficult to diagnose small or hypovascular hepatocellular carcinoma (HCC) even using advanced image modalties. In particular, hypovascular HCCs do not show arterial contrast enhancement which is a typical finding of HCC on computed tomography (CT) and magnetic resonance imaging (MRI). Those also account for a considerable portion of early HCC. We present 54 years-old man who had recurrent hypervascular and hypovascular nodules on three phase CT and gadoxetic acid-enhanced MRI. The nodules were removed by surgical resection and confirmed as combined hepatocellular-cholangiocarcinoma and well differentiated HCC respectively. (J Liver Cancer 2017;17:94-99)
Whole-genome Sequencing of Two Liver Tumors from One Patient
( Tae Hyung Kim ),( Soon Ho Um ),( Yeon Seok Seo ),( Seung Woon Park ),( Han Ah Lee ),( Sang Jung Park ),( Dong-sik Kim ),( Young Dong Yu ),( Sung Won Jung ),( Jae Hyun Han ),( Joo Young Kim ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: There is widely known that numerous genomic variance involved in carcinogenesis. Recent advances in technology make it possible to approach to them closer. The aim of this study is to elicit critical genomic variance in different liver cancer. Methods: We sequenced short-insert (150bp, on average) genomic libraries of two primary multicentric liver tumors and one non-cancerous liver (NCL) tissue surgically resected from a male with chronic hepatitis B. The HiSeq X-Ten sequencer was used with 150- paired-end reads. Among two liver tumors, one was combined hepatocellular- cholangiocarcinoma (CHCCC) and the other was well differentiated hepatocellular carcinoma (HCC). After alignment to human reference genome and removal of duplications, three genomes were compared with each other. Results: We obtained nucleotide sequences covering 106.0 Gb CHCCC genome (37.1 x coverage), 102.6 Gb of HCC genome (35.9 x coverage), and 106.5 Gb (37.3 x coverage) of NCL genome. The sequenced reads covered 99.5% on all three genomes. Comparison of the CHCCC and NCL genomes showed 13,544 somatic single nucleotide variants (SNV), 3,789 small insertions and deletions, and 57 structural variants in CHCCC genome. Distinct SNVs were composed of 2.2% on exon, 37.3% on intron, and 60.5% on intergenic regions. Comparison of the HCC and NCL genomes showed 3,675 somatic single nucleotide variants (SNV), 3,491 small insertions and deletions, and 18 structural variants in HCC genome. Distinct SNVs in HCC were composed of 2.6% on exon, 39.9% on intron, and 57.5% on intergenic regions. Conclusions: The prevalence of somatic SNVs and structural variants in CHCCC is much more than HCC when compared with NCL. And that indicates that more complex process involved in CHCCC. Further researches will be performed for finding significant changes and process, and validation.
박경만(Kyoung-Man Park),엄유식(Yu-Sik Um),이상재(Sang-Jae Lee),권영철(Young-Chul Kwon) 대한설비공학회 2009 대한설비공학회 학술발표대회논문집 Vol.2009 No.-
In the present study, the performance characteristics of R-410A heat-pump chiller in heating mode are experimentally investigated to understand capacity and reliability at the standard, the defrost, the low temperature and the on-off cycle conditions. Heating capacity, water flow rate and COP of R-410A heat-pump chiller are 11.4㎾, 33 l/min and 2.94, respectively. Heating capacity at low temperature condition decreases as the outside temperature decreases. From defrost and on-off cycle conditions, it is confirmed the reliability of R-410A heat-pump chiller.
小靑龍湯이 알레르기 鼻炎에 미치는 效果에 대한 實驗的 硏究
박주호,심성용,엄유식,남혜정,김경준,Park Ju-ho,Sim Sung-yong,Um Yu-sik,Nam Hae-jeong,Kim Kyung-jun 大韓外官科學會 2004 大韓外官科學會誌 Vol.15 No.1
Allergic rhinitis is an inflammation of the nasal mucosa which is triggered by an allergic reaction. When exposed to certain allergens, the IgE covered mast cells degranulate releasing inflammatory mediators and cytokines which results in a local inflammatory reaction. In many recent studies, molecular biological methods have been used to investigate the role of cytokines in pathogenesis and new therapeutic targets of allergic rhinitis. This experimental study was done to research effects of Sochungryong-tang. We have studied effect of mice on OVA-induced production of IL-4, IL-5, IFN-${\gamma}$ by murine splenocytes and effect of OVA-induced total IgE and OVA-specific IgE. The results were as follows; 1. In IL-4 study, Sochungryong-tang treated group was proved significant inhibitory effect(p〈0.005). 2. In IL-5 study, Sochungryong-tang treated group was proved significant inhibitory effect(p〈0.05). 3. In JFN-${\gamma}$ study, Sochungryong-tang treated group was proved significant inhibitory effect(p〈0.000001). 4. In Total IgE, Sochungryong-tang treated group was proved significant inhibitory effect(p〈0.000001). 5. In OVA-specific IgE, Sochungryong-tang treated group didn't showed significant inhibitory effect. Depending upon above results, it is considered that Sochungryong-tang has the inhibitory effect on the allergic rhinitis of mice and suggested that it could be used in relieving patients of the symptoms which are caused by allergic rhinitis.