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      • KCI등재

        Valorization of spent activated carbon in glycerine deodorization unit for methylene blue removal

        Hui Tang Shu,Zaini Muhammad Abbas Ahmad 한국탄소학회 2021 Carbon Letters Vol.31 No.4

        Spent Calgon Filtrasorb activated carbon (SAC) from glycerine deodorization unit was evaluated for the removal of methylene blue (MB). The SAC was used without further modifcation. The SAC was characterized for BET surface area, pH, pHpzc and FTIR to determine the textural and chemical properties of SAC. The batch adsorption study of MB was carried out under diferent initial concentrations (5–500 mg/L), pH (2–11) and contact time (0–200 h). The SAC was found to have high BET surface area, pore volume and average pore diameter of 735 m2 /g, 0.292 cm3 /g and 2.56 nm, respectively. The properties of SAC contributed to high MB adsorption capacity of 283 mg/g. The equilibrium data ftted well with Langmuir model, indicating monolayer adsorption; while the activation energy (Ea) of Dubinin–Radushkevitch (D–R) model is lower than 8 kJ/mol, signifying physisorption. The adsorption kinetics was best illustrated by pseudo-second-order model, while the intraparticle difusion and Boyd models suggested that flm difusion is the rate-controlling step. These fndings showed that Calgon Filtrasorb SAC from glycerine deodorization unit can be potentially reused an adsorbent for the removal of dyes.

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      • KCI등재

        Evaluation of Nurse Practitioners' Professional Competence and Comparison of Assessments Using Multiple Methods: Self-Assessment, Peer Assessment, and Supervisor Assessment

        Hui Yu Liang,Fu In Tang,Tze Fang Wang,Shu Yu 한국간호과학회 2021 Asian Nursing Research Vol.15 No.1

        Purpose: Nurse practitioners (NPs) are increasingly important in healthcare as they play a key role in leading advanced nursing practices. Assessing their professional competence is essential. The aim of this study was to evaluate NPs' professional competencies based on at a collaborative model around NP self and compare different methods of assessment. Methods: This is a cross-sectional study, and a purposive sample of 211 participants in the teaching hospital was used. Methods used were self-assessment (nurse practitioners), peer assessment (physicians and nurses) and supervisor assessment (head nurses). Results: The competence of nurse practitioners was rated as moderate (mean score = 3.45 of a possible 5; SD = 0.59). However, each method resulted in differences in competence for total scores and dimensions. The highest competence was in direct patient care (mean = 3.55, SD = 0.53), and the lowest score was in monitoring the quality of patient care (mean = 3.30, SD = 0.82). post hoc analysis shown that supervisor assessment rated professional competence significantly lower than the method of selfassessment and peer assessment (F = 10.07, p < .001). Conclusion: NPs require an increased effort to continuous learning for enhancing professional competencies. Moreover, using multiple methods for assessment to obtain a more comprehensive and accurate evaluation of NPs’ professional competence.

      • KCI등재

        Virtual Queue Based QoS Layered Vertical Mapping in Wireless Networks

        ( Shu-guang Fang ),( Ri-zhao Tang ),( Yu-ning Dong ),( Hui Zhang ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.6

        Wireless communication is one of most active areas in modern communication researches, QoS (Quality of Service) assurance is very important for wireless communication systems design, especially for applications such as streaming video etc., which requires strict QoS assurance. The modern wireless networks multi-layer protocol stack structure results in QoS metrics layered and acting in cascade and QoS metrics vertical mapping between protocol layers. Based on virtual buffer between protocol layers and queuing technology, a unified layered QoS mapping framework is proposed in this paper, in which we first propose virtual queue concept, give a novelty united neighboring protocol layers QoS metric mapping framework, and analysis method based on dicerete-time Markov chain, and numerical results show that our proposed framework represents a significant improvement over previous model.

      • KCI등재

        Apoptosis in response to heat stress is positively associated with heat-shock protein 90 expression in chicken myocardial cells in vitro

        Xiao-Hui Zhang,Hong Wu,Shu Tang,Qiao-Ning Li,Jiao Xu,Miao Zhang,Ya-Nan Su,Bin Yin,Qi-Ling Zhao,Nicole Kemper,Joerg Hartung,Endong Bao 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.2

        To determine heat-shock protein (Hsp)90 expression is connected with cellular apoptotic response to heat stress and its mechanism, chicken (Gallus gallus) primary myocardial cells were treated with the Hsp90 promoter, aspirin, and its inhibitor, geldanamycin (GA), before heat stress. Cellular viability, heat-stressed apoptosis and reactive oxygen species level under different treatments were measured, and the expression of key proteins of the signaling pathway related to Hsp90 and their colocalization with Hsp90 were detected. The results showed that aspirin treatment increased the expression of protein kinase B (Akt), the signal transducer and activator of transcription (STAT)-3 and p-IKKa/b and the colocalization of Akt and STAT-3 with Hsp90 during heat stress, which was accompanied by improved viability and low apoptosis. GA significantly inhibited Akt expression and p-IKKa/b level, but not STAT-3 quantity, while the colocalization of Akt and STAT-3 with Hsp90 was weakened, followed by lower cell viability and higher apoptosis. Aspirin after GA treatment partially improved the stress response and apoptosis rate of tested cells caused by the recovery of Akt expression and colocalization, rather than the level of STAT-3 (including its co-localization with Hsp90) and p-IKKa/b. Therefore, Hsp90 expression has a positive effect on cellular capacity to resist heat-stressed injury and apoptosis. Moreover, inhibition of Hsp90 before stress partially attenuated its positive effects.

      • KCI등재

        The association of Hsp90 expression induced by aspirin with anti-stress damage in chicken myocardial cells

        Xiao-hui Zhang,Huai-sen Zhu,Zhuang Qian,Shu Tang,Di Wu,Nicole Kemper,Joerg Hartung,Endong Bao 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.1

        The protective effect of aspirin during exposure to heat stress in broiler chickens was investigated. We assayed pathological damage, expression and distribution of Hsp90 protein and hsp90 mRNA expression in chicken heart tissues after oral administration of aspirin following exposure to high temperature for varying times. Heat stress induced increases in plasma aspartate aminotransferase, creatine kinase and lactate dehydrogenase activities while causing severe heart damage, which was characterized by granular and vacuolar degeneration, nuclear shrinkage and even myocardium fragmentation in cardiac muscle fibers. After aspirin administration, myocardial cells showed fewer pathological lesions than broilers treated with heat alone. A high positive Hsp90 signal was always detected in the nuclei of myocardial cells from broilers treated with aspirin, while in myocardial cells treated with heat alone, Hsp90 in the nuclei decreased, as did that in the cytoplasm. Aspirin induced rapid and significant synthesis of Hsp90 before and at the initial phase of heat stress, and significant expression of hsp90 mRNA was stimulated throughout the experiment when compared with cells exposed to heat stress alone. Thus, specific pre-induction of Hsp90 in cardiovascular tissue was useful for resisting heat stress damage because it produced stable damage-related enzymes and fewer pathologic changes.

      • KCI등재

        Port-Site Metastases and Chimney Effect of B-Ultrasound-Guided and Laparoscopically-Assisted Hyperthermic Intraperitoneal Perfusion Chemotherapy

        Ming-Chen Ba,Hui Long,Xiang-Liang Zhang,Yuan-Feng Gong,Zhao-Fei Yan,Shuai Wang,Yun-Qiang Tang,Shu-Zhong Cui 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.3

        Purpose: CO2 leakage along the trocar (chimney effect) has been proposed to be an important factor underlying port-site metastasisafter laparoscopic surgery. This study aimed to test this hypothesis by comparing the incidence of port-site metastasis betweenB-ultrasound-guided and laparoscopically-assisted hyperthermic intraperitoneal perfusion chemotherapy (HIPPC). Materials and Methods: Sixty-two patients with malignant ascites induced by gastrointestinal or ovarian cancer were divided into two groups to receive either B-ultrasound-guided or laparoscopically-assisted HIPPC. Clinical efficacy was assessed from the objective remission rate (ORR), the Karnofsky Performance Status (KPS) score, and overall survival. The incidence of port-site metastasis was compared between the two groups. Results: Patients in the B-ultrasound (n=32) and laparoscopy (n=30) groups were comparable in terms of age, sex, primary diseasetype, volume of ascites, and free cancer cell (FCC)-positive ascites. After HIPPC, there were no significant differences between the B-ultrasound and laparoscopy groups in the KPS score change, ORR, and median survival time. The incidence of port-site metastasis after HIPPC was not significantly different between the B-ultrasound (3 of 32, 9.36%) and laparoscopy (3 of 30, 10%) groups, but significantly different among pancreatic, gastric, ovarian, and colorectal cancer (33.33, 15.79, 10.00, and 0.00%, p<0.001). Conclusion: The chimney effect may not be the key reason for port-site metastasis after laparoscopy. Other factors may play a role, including the local microenvironment at the trocar site and the delivery of viable FCCs (from the tumor or malignant ascites) to the trauma site during laparoscopic surgery.

      • Human Recombinant Endostatin Combined with Cisplatin Based Doublets in Treating Patients with Advanced NSCLC and Evaluation by CT Perfusion Imaging

        Zhang, Feng-Lin,Gao, Er-Yun,Shu, Rong-Bao,Wang, Hui,Zhang, Yan,Sun, Peng,Li, Min,Tang, Wei,Jiang, Bang-Qin,Chen, Shuang-Qi,Cui, Fang-Bo Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

        Aims: To study the effectiveness of human recombinant endostatin injection (Endostar(R)) combined with cisplatin doublets in treating advanced non-small cell lung cancer (NSCLC), and to evaluate outcome by CT perfusion imaging. Methods: From April 2011 to September 2014, 76 patients with advanced NSCLC who were treated with platinum-based doublets were divided into group A (36 patients) and group B (40 patients). Endostar(R) 15mg/day was administered 4 days before chemotherapy and combined with chemotherapy from day 5 in group A, and combined with chemotherapy from the first day in Group B. Endostar(R) in the two groups was injected intravenously for 14 days. Results: Treatment effectiveness in the two groups differed with statistical significance (p<0.05). Effectiveness evaluated by CT perfusion imaging, BF, BV, MTT and PS also demonstrated significant differences (all p<0.05). Adverse reactions in the two groups did not significantly vary (p> 0.05). Conclusions: The response rate with Endostar(R) administered 4 days before chemotherapy and combined with chemotherapy from day 5 in group A was better than Endostar(R) combined with chemotherapy from the first day, and CT perfusion imaging could be a reasonable method for evaluation of patient outcomes.

      • 0346 Occupational Exposure to Lead and Cancer in Two Cohort Studies of Men and Women in Shanghai, China

        Liao, Linda M,Friesen, Melissa C,Xiang, Yong-Bing,Cai, Hui,Koh, Dong-Hee,Ji, Bu-Tian,Yang, Gong,Li, Hong-Lan,Locke, Sarah J,Rothman, Nathaniel,Zheng, Wei,Gao, Yu-Tang,Shu, Xiao-Ou,Purdue, Mark P BMJ Publishing Group Ltd 2014 Occupational and environmental medicine Vol.71 No.suppl1

        <P><B>Objectives</B></P><P>Epidemiologic studies of occupational lead exposure have suggested increased risks of cancers of the brain, kidney, lung, meninges, and stomach; however, the totality of the evidence is inconsistent. To clarify whether lead is a carcinogen, we investigated the relationship between occupational lead exposure and risks of these five cancer sites in two prospective cohort studies in Shanghai, China.</P><P><B>Method</B></P><P>Annual job/industry-specific estimates of lead fume and lead dust exposure were derived from a statistical model that combined expert ratings of lead intensity with inspection measurements collected by the Shanghai Centre for Disease Control and Prevention. The job/industry estimates were applied to the lifetime work histories of subjects from the Shanghai Women’s Health Study (73 363 participants) and the Shanghai Men’s Health Study (61 379 participants) to estimate cumulative exposure to lead dust and lead fume. Cohort-specific relative hazard rate ratios (RRs) and 95% confidence intervals (CI) were estimated using Cox proportional hazards regression models and then pooled using a random effects meta-analysis model.</P><P><B>Results</B></P><P>We observed a statistically significant increased risk of meningioma among individuals with estimated occupational exposure to lead dust or fumes (RR=2.4, 95% CI:1.1–5.0), and in particular among those with an above-median cumulative exposure to dust or fumes (RR=3.1, 95% CI:1.3–7.4). We observed suggestive associations with lead exposure for cancers of the kidney (RR=1.4, 95% CI:0.9–2.3) and brain (RR=1.8, 95% CI:0.7–4.8), and null findings for cancers of the lung and stomach.</P><P><B>Conclusions</B></P><P>Our findings provide additional evidence that occupational lead exposure increases risk of meningioma.</P>

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