從 《隨園詩話》談批評與鑑賞, 考據之間的關系 : the Example of Suiyuan Shihua

吳宏一 韓國外國語大學校 外國學綜合硏究센터 中國硏究所 2004 中國硏究 Vol.33 No.-

Traditional “shihua”writings easily convey an impression of loose organization, as they often lack a rigorous system in form and look like informal essays and notes. In addition, they often offer more than pure literary criticism in content and resemble fiction and conversational discourse, thus inviting criticism of its motley nature. Yet scholars of Chinese literary criticism know that shihua are indispensable reference materials in any research on Chinese poets and poetics. I will take a few statements from Yuan Mei's Suiyuan shihua to illustrate the essence of shihua writings, as well as discuss the relationship among writing, criticism, appreciation and textual research.

FIR 디지틀 필터의 계수양자화효과와 Wordlength의 최적화

權宇鉉,丁弘 경북대학교 공과대학 1980 工大硏究誌 Vol.9 No.-

On FIR digital filter characteristics, roundoff and truncation effects of coefficient quantization are first analysed and then those equations are validated experimentally. When the product NB of tap number N, and bit number B is fixed, the optimal point (N, B) where the RMS amplitude deviation between ideal and quantized filter is minimum is found to be exist uniquely and obtained experimentally with digital computer simulation.

AM-FM, AM-PM 兩立的인 AM 스테레오 方式의 周波數 스펙트럼 分布와 帶域幅에 관한 연구

丁弘,權宇鉉 경북대학교 공과대학 1981 工大硏究誌 Vol.10 No.-

Amongst various modulation methods for compatible AM stereo, the two systems, AM-FM and AM-PM, whose methods of modulation and characteristics of signals are similar to each other, have been discussed in this paper. Most of all, the characteristics of spectrum and bandwidth of these systems are important practically and cannot be analyzed easily by simple AM, FM or PM approximation since these characteristics are varying according to both the magnitude and the phase of two input signals (left and right channels). In the light of these facts, the spectrum and bandwidth of AM-FM and AM-PM systems was first analyzed quantitatively considering intermodulation effects caused by nonlinear modulation functions. Then, these results were simulated on a digital computer to be validated and compared with the data and explained on the basis of frequency spectrum and bandwidth.

모노와 兼用 AM스테레오 變調信號의 페이서 解釋

權宇鉉,丁弘 慶北大學校 1982 論文集 Vol.33 No.-

In most cases of the analysis of analog modulated signals, phasor interpretation is required to calculate the frequency spectrum and therefore its bandwidth. In this paper, the comprehensive modulated signals including Monos and Compatible AM Stereos are analized to get the phasor diagram and therefore to locate the sidebands without mathematical complexity as much as possible. At first, a series of simple modulated signals are considered and then these results are applied to obtain phasors of other sophisticated modulation systems easily. Then the practical AM compatible stereo systems including the newly proposed one are introduced and simulated for their time domain operations on a digital computer.

요추 추간판 탈출증 환자 30例의 요추신연법 倂用에 대한 臨床的 考察

김재홍,조명래,채우석 大韓鍼灸學會 2003 대한침구의학회지 Vol.20 No.3

Objective : The purpose of this report is to usee more Chuna treatment clinically by comparing the improvement of Back pain and Sciatica between Common treatment Group and Common treatment with Chuna treatment Group. Methods : This study was carried out on 30 patients with Back pain and Sciatica who ere hospitalized in Dongshin Univ. Oriental Hospital form April 2001 to December, 2002. Group A of 15 patients wer taken both common treatment and Chuna treatment. And Group B of 15 patients were only taken common treatment. And after 10 days of admission, we checked and compared VAS(Visual Analogue Scale) and improvement index out of these two groups. Results : The result of the VAS(Visual Analogue Scale) and improvement index of comparison analysis between two groups after 10 days, shows that the improvement of Back pain and Sciatica in Common treatment with Chuna treatment Group is more effective than that in Common treatment Group.

Hong Kong Panel Study of Social Dynamics (HKPSSD): Research Designs and Data Overview⁺

( Xiaogang Wu ),( Clear Water Bay ),( Hong Kong Sar ) 한국보건사회연구원 2015 한국복지패널 학술대회 논문집 Vol.8 No.-

The Hong Kong Panel Study of Social Dynamics (HKPSSD)aims to establisha city-wide representative household panel survey to track socioeconomic changes and its impact on people`s livelihood in Hong Kong. The content covers housing, economic activity and consumption at household levels and education, marriage, fertility, employment, health, daily social activities, mental health and social attitude at individual levels. Three waves of data have been completed in 2011, 2013 and 2015, respectively. 3,214 households, 7,218 adults and 958 children have been interviewed in the benchmark survey (Wave 1), among which 2,165 households, 4,270 adults and 623 children are re-interviewed in the second wave. In addition, a refreshment sample of 1,007 households (including 1,960 adults and 145 children) with new themes was added in 2014, which together with those remaining in Wave 2, are followed in Wave 3 in 2015. This essay introduces the background, research designs, and content coverage of three waves of HKPSSD, and presents some descriptive statistics of relevant variable in the data. HKPSSDis expected to serve an important database for social science research and policy study in Hong Kong, and for comparative analyses of Chinese societies in Hong Kong, Taiwan and mainland China.

Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA : GSK3β inhibition via PKA and LKB1

Wu, Hong Min,Lee, Chan Gyu,Hwang, Se Jin,Kim, Sang Geon Wiley (Blackwell Publishing) 2014 British journal of pharmacology Vol.171 No.11

<P>Methylene blue (MB) has recently been considered for new therapeutic applications. In this study, we investigated whether MB has antioxidant and mitochondria-protecting effects and can prevent the development of toxicant-induced hepatitis. In addition, we explored the underlying basis of its effects.</P>

Can CD44+/CD24- Tumor Cells Be Used to Determine the Extent of Breast Cancer Invasion Following Neoadjuvant Chemotherapy?

Hong Wu,Ruhui Li,XiaoDong Hang,Ming Yan,Feng Niu,Lidi Liu,Wei Liu,Song Zhao,Shaokun Zhang 한국유방암학회 2011 Journal of breast cancer Vol.14 No.3

Purpose: To investigate the distribution of CD44+/CD24- cells in breast cancers in relation to tumor size before and after the administration of neoadjuvant chemotherapy. Methods: CD44+/CD24- tumor cells obtained from breast cancer specimens were characterized in vivo and in vitro using tumor formation assays and mammosphere generation assays, respectively. The distribution of CD44+/CD24- tumor cells in 78 breast cancer specimens following administration of neoadjuvant chemotherapy was also evaluated using immunofluorescence assays, and this distribution was compared with the extent of tumor invasion predicted by Response Evaluation Criteria in Solid Tumours (RECIST). Results: In 27/78 cases, complete remission (CR) was identified using RECIST. However, 18 of these CR cases were associated with a scattered distribution of tumor stem cells in the outline of the original tumor prior to neoadjuvant chemotherapy. After neoadjuvant chemotherapy, 24 cases involved cancer cells that were confined to the tumor outline, and 21 cases had tumor cells or tumor stem cells overlapping the tumor outline. In addition, there were 6 patients who were insensitive to chemotherapy, and in these cases, both cancer cells and stem cells were detected outside the contours of the tumor volume imaged prior to chemotherapy. Conclusion:CD44+/CD24- tumor cells may be an additional parameter to evaluate when determining the extent of breast cancer invasion.

hMSH2 and nm23 Expression in Sporadic Colorectal Cancer and its Clinical Significance

Wu, Hong-Wei,Gao, Li-Dong,Wei, Guang-Hui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Objective: To study the expression of the mismatch repair proteins hMSH2 and nm23 in sporadic colorectal cancer, determine any inter-relationship, and further investigate any clinical significance. Methods: Expression of hMSH2 and nm23 proteins was assessed in 87 colorectal cancer tissues by SP immunohistochemistry, with analysis of survival using follow-up data. Results: In the sporadic colorectal cancer tissues, nm23 protein expression appeared independent of the histological type (P>0.05), but correlated with the invasion depth and lymphatic metastasis (P<0.05). In contrast, hMSH2 protein expression was not significantly correlated with these clinicopathologic features (P>0.05), although it positively correlated with that of nm23 protein in the sporadic colorectal cancers (rs=0.635, P<0.05). Combined expression of the two was found to be related with invasion depth, lymphatic metastasis and prognosis of sporadic colorectal cancer (P<0.05). Conclusion: nm23 protein level was related with the degree of malignancy, and could be used as an index to predict the invasion and metastasis potential. The expression of hMSH2 protein is positively correlated that of nm23 protein, and the combined expression of the two has certain guiding significance for the prognosis of sporadic colorectal cancer.

Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts antiinflammatory effect by direct inhibiting toll like receptor 4 signaling pathway

Hong-Lin Xu,Guang-Hong Chen,Yu-Ting Wu,Ling-Peng Xie,Zhang-Bin Tan,Bin Liu,Hui-Jie Fan,Hong-Mei Chen,Gui-Qiong Huang,Min Liu,Ying-Chun Zhou 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.1

Background: Panax ginseng Meyer (P. ginseng), a herb distributed in Korea, China and Japan, exerts benefits on diverse inflammatory conditions. However, the underlying mechanism and active ingredients remains largely unclear. Herein, we aimed to explore the active ingredients of P. ginseng against inflammation and elucidate underlying mechanisms. Methods: Inflammation model was constructed by lipopolysaccharide (LPS) in C57BL/6 mice and RAW264.7 macrophages. Molecular docking, molecular dynamics, surface plasmon resonance imaging (SPRi) and immunofluorescence were utilized to predict active component. Results: P. ginseng significantly inhibited LPS-induced lung injury and the expression of proinflammatory factors, including TNF-a, IL-6 and IL-1b. Additionally, P. ginseng blocked fluorescence-labeled LPS (LPS488) binding to the membranes of RAW264.7 macrophages, the phosphorylation of nuclear factor-kB (NF-kB) and mitogen-activated protein kinases (MAPKs). Furthermore, molecular docking demonstrated that ginsenoside Ro (GRo) docked into the LPS binding site of toll like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD2) complex. Molecular dynamic simulations showed that the MD2-GRo binding conformation was stable. SPRi demonstrated an excellent interaction between TLR4/MD2 complex and GRo (KD value of 1.16 × 10<SUP>-9</SUP> M). GRo significantly inhibited LPS488 binding to cell membranes. Further studies showed that GRo markedly suppressed LPS-triggered lung injury, the transcription and secretion levels of TNF-α, IL-6 and IL-1β. Moreover, the phosphorylation of NF-kB and MAPKs as well as the p65 subunit nuclear translocation were inhibited by GRo dose-dependently. Conclusion: Our results suggest that GRo exerts anti-inflammation actions by direct inhibition of TLR4 signaling pathway.