Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells

( Jae-sung Ryu ),( Kyu-tae Chang ),( Ju-taek Lee ),( Malg-um Lim ),( Hyun-ki Min ),( Yoon-ju Na ),( Su-bin Lee ),( Gislain Moussavou ),( Sun-uk Kim ),( Ji-su Kim ),( Kinarm Ko ),( Kisung Ko ),( Kyung- 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.6

The ACKNOWLEDGEMENTS should be corrected as follows, "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea. The published article in this journal was a part of the 2013 Doctoral thesis of Jae-Sung Ryu submitted to Wonkwang University, Korea." and not "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea."

식이섬유 보충용 식품의 섭취에 따른 여성의 비만관련 체구성 요인 및 배변만족도의 변화

임용택,강선영,김재등,김성수,김재우,이충영,김정모 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

The Purpose of this study was to investigate the effect of functional food including dietary fiber supplementation on body composition concerning obesity and defecation satisfaction of women. Twelve young healthy women but had defecation difficulty were participated as a subject. Body weight, %body fat, WHR mesurement and defecation satisfaction questionnaire were performed before and after 2 weeks' supplementation. The results of this study were as follows : First, Body composition concerning obesity such as body weight(p=.0065), % body fat(p =.0004) and WHR(p=.0007) after 2 weeks' functional food including dietary fiber supplementation was decreased significantly. Second, defecation satisfaction functional food including dietary fiber supplementation was increased significantly(p = .0039). This results suggested that functional food including dietary fiber supplementation should be recommended as effective dietary food for persons with obesity and defecation difficulty.

구리 지역에서 조사한 고혈압의 인지도, 치료률 및 관리률

홍철호,김순길,홍택원,이제,신진호,이재웅,김경수,김정현,임헌길,이방헌 대한간질학회 2003 대한간질학회지 Vol.9 No.1

쇄골 중간부 골절후 불유합 및 지연 유합의 원인

윤정로,심재익,김택선,이성종,김영배,김학준,안국환,장재영,홍명표 대한골절학회 2002 대한골절학회지 Vol.15 No.4

쇄골 중간 1/3 부위의 골절은 치료 결과가 양호하여 보존적 치료가 원칙적으로 받아 들어지고 잇으며 불유합에 대한 빈도도 낮은 것으로 되어 있다. 그러나 최근 전위 및 단축의 정도가 심할 경우 높은 불유합의 결과와 불량한 임상 결과를 보고하고 있어 이런 예에 대해선 수술적 치료를 권장하고 있다. 저자들은 단축 및 전위의 정도와 불유합의 연관성을 알아보고자 하였다. 연구 대상 및 방법 : 1993년 2월부터 2002년 1월까지 본원에 내원 했던 성인 중간부 쇄골 골절 환자 194명 중 완전 전위를 보인 78례를 조사하여 이중 63례를 대상으로 분석하여 후 향적 연구를 시행하였다. 4개월 추시 후에도 방사성 사진상 유합 소견이 관찰되지 않으면 불유합의 유의성을 알아보고자 하였다. 결 과 : 63례 중 불유합 및 지연 유합을 소견을 보인 환자는 15(23%)례였다. 골유합을 보인 48례의 단축은 평균 8.6㎜(2㎜-17㎜)였고, 전위는 평균 9.7㎜(2-22㎜)였다 .불유합 및 지연 유합을 보였던 15례에서 단축은 평균 14.5㎜(3㎜-37㎜), 전위는 평균 17.3㎜(4-25㎜)였다. 18㎜이상 단축이 있었던 경우 불유합의 발생과는 통계학적으로 유의성을 나타내었고(Fisher's exact test, p<0.01), Chi-square test상 16㎜ 이상의 전위를 보였던 경우 불유합 발생과 통계학적으로 의미가 있었다(p<0.01). 결 론 : 쇄골 골절 특히 중간 1/3의 골절은 비교적 보존적 치료에 결과가 좋은 것으로 되어 있으나, 전위 및 단축이 심한 경우 불유합에 대한 가능성이 높이 때문에 보다 경과 관찰시 유합의 진행이 없으면 적극적인 치료를 고려해야한다. Purpose : Because the prognosis of the mid 1.3 clavicle fracture is good, the conservative treatment with a figure of 8 bandage is the gold standard and the nonunions are rare. However, recently surgical treatment is recommended when the shortening and displacement is severe because of the high nonunion rate and the poor clinical result. This study was undertaken to evaluate that the shortening and displacement at fracture site are associated with the development of nonunion. Materials and Methods : We analysed the 194 fractures of mid 1/3 clavicle in adults which had been treated conservatively from February 1993 to January 2002 and did the retrospective study. Of these, 78 cases were originally in the middle third of the clavicle and had been completely displaced. We reviewed 63 of these cases. The shortening and displacement at the fracture site was measured on the initial roentgenogram. And the analysis of the patients' chart was done for another predisposing nonunion factors. Nonunion and delayed union are considered to be present when there has been little or no progression of clinical or radiographic healing at a minimum of 4 months after injury. Results : 15 of the 63 cases had developed nonunion.. The average 8.6㎜(2㎜-17㎜) shortening and average 9.7㎜(2-22㎜) in the union patients. The average 14.5㎜(3㎜-37㎜) shortening and average 17.3㎜(4-25㎜) in the nonunion patients. We found that initial shortening ≥18㎜(Fisher's exact test, p<0.01) and initial displacement ≥ 16㎜(Chi-square test. p<0.01)at the fracture site were significantly associated with the development of nonunion. Conclusion : The conservative treatment with figure-80-bandage is the gold standard in the clavicle middle one third fracture. However, the nonunion is commonly occurs in the cases of more of severely shortened and displaced fractures. If there are no signs of callus formation and the patient complains of pain after several week, osteosynthesis should be considered.

인공 건조법에 의한 마른 명태의 품질 개선에 관한 연구 : 2. Some Methods for Hot-air Dehydration of Alaska Pollack 2. 열풍 건조법에 의한 마른 명태 제조

金用根,金敬順,卞在亨,李應昊,梁升澤 釜山水産大學校 1972 釜山水産大學 硏究報告 Vol.12 No.1

북양명태를 원료로서 마른명태를 가공하는 실험을 하여 다음과 같은 결과를 얻었다. 원료를 해동하여 내장을 제거하고, 그대로 29시간 열풍건조하여 마른명태를 가공할 수 있었으며, 제품의 수율은 22% 수분은 18%였다. 또한 원료어를 등갈이한 다음 머리, 내장, 흑막을 제거하고, 염장한 다음 22시간 열풍건조하여 건조시간도 단축할 수 있고, 색택도 좋은 제품을 만들 수 있고, 수율은 약 12%였다. 또한 원료어를 fillet로 처리하여 염장한 다음 열풍건조하므로서 건조시간을 더욱 단축할 수 있었고, 포장 및 조리하기에 편리한 제품을 가공할 수 있었다. 제품의 수율은 어체의 크기에 따라 차이가 있어 10∼22%였다. 그리고 채육기로 육을 채취한 다음 과산화수소를 써서 거품을 일어켜 새로운 형태의 다공성인 박층건제품을 가공할 수 있었고, 이 다공성 박층건제품은 흡수성이 좋아 instatant 식품으로 이용 가능하다는 결론을 얻었다. In this paper, some dehydration methods for frozen Alaska Pollack Theragra chalcogramma were studied. The cabinet type drier was used for the study. Samples were dehydrated for appropriate time at the air temperature of 38 to 40℃ under the air stream of 3m/sec. The frozen samples were defrosted, eviscerated, and hot-air dehydrated for 29 hours. The yield of dehydrated product was about 22% and moisture content was 18%. The brine salted samples which were headed, split and skinned were also hot-air dehydrated under the same conditions. This dehydration process could reduce dehydration time. The yield of dehydrated product was about 12% and moisture content was about 20%. For another method, frozen samples were first defrosted, washed thoroughly to remove dirt, slime and scales, and then beheaded, skinned and filleted. The fillet was dehydrated after brine salting. The yield was 10 to 22% and moisture content was 12%. The tissue of these hot-air dehydrated products such as round, split and fillet were very firm and difficult to reconstitute. In order to obtain dehydrated product of agreeable texture, another dehydration process was examined. Chopped meat was dipped in alkaline solution of 0.4% hydrogen peroxide for 30 minutes and then agitated for 10 minutes. By these treatment the foamy and emulsified minced meat was spread on a nylon net seated on metal tray, drained, and dehydrated. A better result was obtained by this process comparing with other's. This could be explained for the reason that the process resulted in the meat flake porous by which the meat could be rapidly reconstituted. The texture of the porous meat flake was good for a convenience food.

화학기상응축 공정으로 제조한 Fe 나노입자의 TEM 미세조직 및 결정화거동

김택수,이희정,오익현,한재길,최철진,이병택 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.12

Iron and iron nitride nanoparticles were synthesized by chemical vapor condensation (CVC) process, using a precursor of Fe(CO)_(5) and carrier gas of NH₃. Phase change and crystallization behaviors of as received particles were mainly examined by TEM technique. Only α-Fe nanoparticles were formed at the lowest decomposition temperature of 500℃. As the temperature increased, the crystallization of α-Fe nanoparticles was suppressed and Fe₃N nanoparticles were begun to be formed. Finally full crystallization of Fe₃N was observed at 1000℃. Typical size of the α-Fe and Fe₃N particles was less than 30 nm in diameter.

양수검사에서 small supernumerary marker chromosomes(sSMCs) 발견과 산전상담

문성택,김윤숙,전섭,최승도,선우재근,배동한 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

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이질균 세포 단백의 분석에 있어서의 은 염색의 이용

김재석,이유철,조동택 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.3

To study the mechanism of virulence of Shigella, sodium dodecyl sulfate-polyacrylamide gel electro-phresis was conducted on membrane fractions from 2 strains of HeLa cell invasive Shigella flexneri. After electrophresis gel slab was stained first with Coomasie brilliant blue R-250 staining then followed by silver staining, more than tenfold increase in sensitivity was achieved over Coomasie brilliant blue R-250 stain. The total membrane fraction from Shigella flexneri 85DH38 stained with silver showed 12 protein bands; 180 kilodalton(K), 127K, 100K, 78K, 64K, 55K, 47K, 45K, 43K, 39K, 38K and 12.8K, but stained with Coomassie brilliant blue R-250 showed only 5 bands. The sodium lauryl sarcosinate (SLS) soluble membrane fraction showed prominent 100K band and less prominent 5 bands; 180K, 78K, 64K, 55K and 45K. The SLS insoluble membrane fraction showed prominent 47k, 39K, and 38K bands of porin proteins and less prominent 43K and 12.8K band. The total membrane fraction from Shigella flexneri 78B-1 showed 7 protein bands which also appeared in the fractions from Shigella flexneri 85DH38. There were 5 bands of low molecular weight proteins (10K to 20K) in gel run at 20 ㎃ but not appeared at 35 ㎃.

MMPI 프로파일에서의 人爲的인 反應

金在煥,元鎬澤 大韓神經精神醫學會 1978 신경정신의학 Vol.17 No.4

The purpose of this study was to examine various patterns of artificial responses in the MMPI profile and its interpretability, and consequently to improve the validity of MMPI as a diagnostic tool. Three types of artificial responses are identified as follows: random response, social conformity or non-conformity, and all yes or all no response. The data of random response were obtained from 30 male and 30 female hypothetical cases by using a table of randon numbers. The data of social conformity and non-conformity response obtained from 200 normal subjects (M=118, F=82): Any item that was responded in a same direction in more than 50% of the responses was counted as social conformity response and any item that 50% of the responses was regarded as social non-conformity response. The profiles of these responses were as follows; (1) Random responses, social non-conformity, and all yes responses suggested "psychotic pattern" with an extremely high elevation on F scale. (2) All no responses showed highly defensive "neurotic tendency" with highly elevated L,& K scales and relatively high F scale. This study suggested that artificial response profiles postulated theoretically invalid were to be useful psychodiagnostic cue in clinical practice.

PD 제어기를 이용한 회전시스템의 동특성에 관한 연구

김택현,김종태,김재경 朝鮮大學校 機械技術硏究所 2005 機械技術硏究 Vol.8 No.1

기계 회전 시스템을 통하여 응답특성 및 제어효과에 대한 연구를 목적으로 하여 PD제어기를 사용하여 응답특성을 확인하였는데 제어기를 사용함은 얻고자하는 대상 플랜트의 출력 특성을 제어하는데 목적이 있다. 우선, 실험으로 들어가 시스템의 관성 (inertia), 스프링 강성(spring stiffness), 감쇠계수(damping coefficient) 등의 매개변수 값들을 측정하고, 하드웨어 게인 값을 정의한다. 다음으로 PD제어기의 설계를 하는데 우선 강체로 모델링된 시스템에서의 step 응답, ramp 응답, parabolic 응답과 sinusoidal 응답에서의 비례게인, 미분게인 값이 시스템에 미치는 영향을 통하여 제어특성과 효과를 알아보고, 2자유도(two degree of freedom) 기계 회전 시스템에 대하여 PD제어실험을 통하여 회전 시스템의 상승시간(rising time), 정착시간 (settling time) 등의 응답속도 개선, 그리고 오버슈트(overshoot), 언더슈트(undershoot) 등의 응답성능의 향상을 꾀한다. The mechanical rotation system is made up of belts, mass disks and gears. This precise piece of equipment is controlled electro-mechanically by the motor and operation program. The control strategy of the system can be changed by belts' stiffness and change of the mass and gear. This system can be modeled as a rigid body, and also finds broad application in such diverse fields as machine tools, the cruise control system in automobiles, and control in the attitude and gimbals of spacecraft. This system proves the necessity and effect of a closed loop control. The study of the mechanical rotation system excited by its base motion is not only able to predict the rotational performance, but obtain the fundamental data for vibration isolation. In this thesis, we studied the response abilities such as steady overshoot, undershoot and ect. and the response velocities such as rising time, settling time, and ect. in the mechanical rotation system. through PD control experiment..