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- 저자 : 이성종 (검색결과 241 건)
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이성종,이석하,이동기,유연식,심재익,김택선,조홍만 대한골절학회 2000 대한골절학회지 Vol.13 No.2
Purpose: In the proximal tibial condylar fractures, the authors analyzed the treatment results clinically and radiologically, after arthroscopically assisted accurate anatomical reduction of articular surface and rigid internal fixation with early mobilization. Materials and methods: We reviewed 56 cases of tibial condylar fracture that were treated at our the orthopaedic department between January 1990 and December 1996 and the follow-up period was 1 year above. According to Schatzker's classifications, we classified the type of fracture and we analyzed the results by average union time and Porter s criteria after accurate anatomical reduction of articular surface and rigid internal fixation in 51 cases, and 22 cases of total 51 cases were arthroscopically assisted redcution of articular surface and internal fixation. Results: According to Schatzker's classification, Type I 15 cases, Type II 14 cases, Type III 6 cases, Type IV 7 cases, Type V 3 cases, Type VI 11 cases. Associated soft tissue injuries were total 22 cases that were MCL injuries 12 cases, lateral meniscal injuries 6 cases. The average union time was 15.5 weeks and by Porter's criteria, 56 cases, of which 39 cases(71%) had an good result. Conclusion: we considered that good results can be obtained by assistant use of arthroscopy and rigid internal fixation with early mobilization, that accurate diagnosis and appropriate treatments of accampaning injuries according to the type of fractures, and accurate anatomical reduction of articualr surface.
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이성종,안국환,윤정로,심재익,김택선,김영배,김학준,장재영,홍명표 대한골절학회 2002 대한골절학회지 Vol.15 No.4
목 적 : 쇄골 중간 1/3 부위의 골절은 치료 결과가 양호하여 보존적 치료가 원칙적으로 받아 들여지고있으며 불유합에 대한 빈도도 낮은 것으로 되어 있다. 그러나, 최근 전위 및 단축의 정도가 심할 경우높은 불유합의 결과와 불량한 임상 결과를 보고하고 있어 이런 예에 대해선 수술적 치료를 권장하고있다. 저자들은 단축 및 전위의 정도와 불유합의 연관성을 알아보고자 하였다. 연구 대상 및 방법 : 1993년 2월부터 2 0 0 0 2 년 1월까지 본원에 내원 했던 성인 중간부 쇄골 골절 환자1 9 4 명 중 완전 전위를 보인 7 8례를 조사하여 이중 6 3례를 대상으로 분석하여 후 향적 연구를 시행하였다. 4개월 추시 후에도 방사선 사진상 유합 소견이 관찰되지 않으면 불유합 혹은 지연 유합으로 판정을 하였다. 단축 및 전위 정도를 처음 방사선 사진에서 측정하였고 이들과 불유합의 유의성을 알아 보고자 하였다.. 결 과 : 63례 중 불유합 및 지연 유합을 소견을 보인 환자는 1 5 ( 2 3 % ) 례였다. 골유합을 보인 4 8례의 단축은 평균 8 . 6 m m ( 2 - 1 7 m m ) 였고, 전위는 평균 9.7mm (2-22mm)였다. 불유합및 지연 유합을 보였던 1 5례에서 단축은 평균 14.5mm(3-37mm), 전위는평균 1 7 . 3 m m ( 4 - 2 5 m m ) 였다. 18mm이상단축이 있었던 경우 불유합의 발생과는 통계학적으로 유의성을 나타내었고( F i s h e r ’s exact test, p〈0.01). Chi-square test상1 6 m m이상의 전위를 보였던 경우 불유합 발생과 통계학적으로 의미가 있었다( p〈0 . 0 1 ) .
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위선암종의 예후인자로서 E-cadherin, CD44s & CD44v6의 발현
이성종,이태진,김미경,박언섭,홍연표,유재형 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.1
Previous studies have shown that cell adhesion molecules and angiogenic factors play an important role in the growth, progression, and metastasis of gastric cancers. Among the cell adhesion molecules, epithelial cadherin(E-cadherin) and CD44 are important in cancer invasion and metastasis. Loss of adhesive functions and gain of new adhesive functions are thought to be crucial in metastatic process. Vascular endothelial growth factor(VEGF) is another recently identified growth factor with significant angiogenic properties. the purpose of this study is to evaluate the significance of E-cadherin and CD44(standard, CD44s and splice variants, CD44v6), and VEGF expression in gastric adenocarainomas. Immunohistochemical straining of E-cadherin, CD44v6 and VEGF in formalin-fixed paraffin-embedded tissue sections of 125 gastric adenocarcinomas was done and correlations of the expression of E-cadherin, VEGF, CD44s, and CD44v6 with various clinico pathologic factors were studied. The overall expression rates of E-cadherin, VEGF, Cd44s and CD44v6 were 48.8%(61/125), 36.8%(46/125), 24.0%(30/125), and 47.2%(59/125), respectively, The E-cadherin and VEGF expression rates, even though statistically not significant, were inclined to correlate with tumor differentiation, depth of invasion and lymph node metastasis. The CD44s and CD44v6 expression rates were correlate with depth of invasion, lymph node metastasis, and survival rate. These data suggest that the expression of CD44s and CD44v6 may be more likely involved in the tumor progession and lymph node metastasis than E-cadherin and VEGF. So it may also be useful as a predictor of prognosis.
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대학 교육과정의 혁신적 개편을 통한 융합과학자 육성 방안
이성종,황은희,남기은,최철원 한국기술혁신학회 2009 한국기술혁신학회 학술대회 발표논문집 Vol.2009 No.5
Many of the renowned scientists for their innovative achievements in the scientific history have strived to study not only their major discipline but also other subjects so that they have pioneered new academic fields. However, science and technology has been developed divided into diverse fields in the last few centuries. Rapidly increased knowledge and information from each field has made it difficult for scientists to be thoroughly acquainted with other fields of study. Interdisciplinary science, a field of study that crosses traditional boundaries between academic disciplines, is a new emerging research area rather than already existing academic area. It is necessary to cultivate interdisciplinary scientists for the advance in interdisciplinary science. The existing four year bachelor programs seem to be inefficient to cultivate interdisciplinary scientist due to reinforced barriers between academic disciplines. This study suggests that seven year consilience courses must be established to improve the national level of interdisciplinary science. 과학사에 혁신적인 업적을 남긴 학자 중 다수가 여러 학문 분야에 걸쳐 수학하고 이를 응용하여 새로운 학문 분야를 개척한 것으로 보인다. 그러나 지난 몇 세기동안 과학기술은 여러 학문분야로 분화되면서 발전하였으며 각 분야별로 늘어나는 지식과 정보는 학문간 장벽을 높이는 결과를 초래하였다. 융합과학 분야는 기존의 전통적 학문 분야가 아닌 새로운 학제간 영역을 의미 하며 이러한 분야의 진보와 발전을 위해서는 다학문적 기초를 갖춘 융합과학자의 양성이 필요하다. 하지만 높아진 학문간 장벽으로 인하여 지난 수 십년 동안 유지되어 온 현행 4년제 학사 교육과정은 다학문적 기초를 갖춘 융합과학자를 양성하기에 효율적이지 못하다. 따라서 국가 융합 과학 수준의 도약을 위해 대학 학사과정에 통섭학과를 신설하되 7년제로 추진할 것을 제안한다.
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이성종,박영진,이석하,이동기,김택선,심재익,이덕용,유연식 대한골절학회 1999 대한골절학회지 Vol.12 No.1
The supracondylar fracture of the humerus is the most common fracture of the elbow in children and is occasionally associated with significant residual complications such as cubitus varus deformity. Clincal analysis was performed on 32 patients with displaced supracondylar fractures of humerus, who were treated either by closed reduction and percutaneous pinning or by open reduction and internal fixation. The results were as follows: 1. The average age of the children was 6.8 years old in both sexes, and male to female was 21 : 11. 2. The extension type was 26 cases(82%), flexion type was 6 cases(18%) and the left side was more frequently involved. 3. According to Pirone classification, type II was 14 cases, type III 18 cases. 4. There was no significant difference in the mean duration of bony union between the percutaneous group and the open reduction group. 5. Cubitus varus deformity and limitation of elbow motion were more common complications in open reduction group.
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