말초혈액 내 백혈구수와 대사증후군과의 연관성

황상태,김범수,황상준,서정열,김병진,이원영,성기철,강진호,김선우,이만호,박정로 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.3

방광질루 치험

황선태,이종찬,양상국,김홍섭,노용수 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Vesicovaginal fistula is a distressing complication which may follow hysterectomy, prolonged labor, chemical cauterization due to uterine prolapse, radiation therapy and cervix cancer. The management of vesicovaginal fistula still remains controversial in regard to the type of approach and timing of repair but the classic opinion is to wait 3 to 6 months to allow the surgical inflammatory reaction to subside. We experienced 4 cases of vesicovaginal fistula which were as follows; Case 1: 51-year-old The vesicovaginal fistula, about 3.0cm in diameter, after laparascopic hysterectomy 15 days ago was repaired with interposition of a gracilis muscle flap via the transvaginal route. Case 2: 38-year-old The vesicovagianl fistula, about 2.5cm in diameter, after Cesarean section 5 years ago was repaired with interposition of the omental flap via the transabdominal route because she had been accompanied by an overian cyst. Case 3: 46-year-old The vesicovaginal fistula, about 2.5cm in diameter, after manual self abortion at home 30 years ago was repaired with interposition of fibro-fatty tissue in labia via the transvaginal route. Case 4: 43-year-old The vesicovaginal fistula, about 2.0cm in diameter, after prolonged labor 12 years ago was repaired with interposition of the fibro-fatty tissue in labia via the transvaginal route. There noted no complications or recurrence during the minimal 1 year follow-up.

μBGA 무연솔더 (Sn-3.5Ag-0.7Cu)와 전해 및 무전해 Ni 도금층 계면의 열적 안정성

오성룡,황태복,오용준 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.9

The morphology and thermal stability of the interfacial phases in the joints between lead free solder (Sn3.5AgO.7Cu) and electroless Ni-P (12 at%P) and electro Ni under bumper metallizations(UBM) were investigated as a function of thermal aging. Samples were prepared by reflowing at 250℃, N₂ atmosphere and aging in the range of 125 to 170℃ for up to 1000h. After reflow, in the electrolytic Ni/solder joint, the interfacial IMC was mostly Nirich (Ni,Cu)₃Sn4 with an addition of about 8 at% Cu while in electroless Ni-P/solder joint it showed both Cu-rich (Cu,Ni)_(6)Sny and Ni-rich (Ni,Cu)₃Sn4. After relatively short aging time, the interfacial IMC on electrolytic Ni layer has developed into the dual-layed structure of (Ni,Cu)₃Sn₄(bottom) and (Cu,Ni)_(6)Sny(top). But IMC on electroless Ni-P layer were (Cu,Ni)_(6)Sn_(6) and changed into the dual structure only after long aging time of 500h. The growth rate of IMC with aging was higher on electrolytic Ni layer than on electroless Ni-P. The different behavior of electroless Ni-P/SAC joint came from Ni₃P formation between IMC and electroless Ni-P layer which retards diffusion of Ni and Sn to the opposite direction. The thickness of Ni₃P layer was propositional to that of IMC. For longer aging time, NiSnP layer was found at the interface between IMC and Ni₃P layer. Interestingly, in spite of low consumption rate of electroless Ni-P than electrolytic Ni layer by suppressing IMC growth, the interface of Ni-P/IMC was locally hollowed by the accelerated reaction of the Ni-P layer through local thickness reduction of Ni₃P and NiSnP layers. This reduced the effective remaining thickness of Ni-P layer.

新生兒의 聽成腦幹反應

劉溶相,禹泳琮,黃泰周 全南大醫大 1986 전남의대학술지 Vol.23 No.2

韓國人에서 HumFIBRA/FGA와 D21S11 遺傳座의 對立遺傳子 頻度와 遺傳的 變異의 分析

김윤신,황적준,이혜린,구태완,한길로,김성민,이혜승 大韓法醫學會 1998 대한법의학회지 Vol.22 No.1

Allele-and genotype frequencies of the two short tandem repeat (STR) loci, HumFGA and D21S11, were determined in Korean population(n=196). DNA typing was accomplished by applying fluorescence-labeled PCR products and a differently labeled sequenced allelic ladders, followed by automated analysis using ABI 377 automatic sequencer and GeneScan 2.02 software. Prior to typing, allelic ladder of each locus was constructed with a combination of all alleles occuring from the population sample. A total of 15 alleles and 48 genotypes with the heterozygosity of 0.854 for HumFGA, and 12 alleles and 33 genotypes with the heterozygosity of 0.787 for D21S11 are observed in a population of 196 genetically unrelated individuals. No deviations from Hardy-Weinberg equilibrium were observed(p=0.753 for HumFGA, p=0.262 for D21S11). The data presented here (power of discrimination and average power of exclusion) show that both STR Loci, HumFGA and D21S11, are very informative for individualization from criminal evidences, and are also useful for parentage testing.

신이식에서 이식신의 생존분석

오선미,김종학,황평주,구영선,강민규,나기량,김종섭,김성숙,이강욱,신영태,설종구,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To investigate the prognostic factors for the survival of transplanted kidney in patients with end-stage renal failure, 59 cases of renal transplantation from September 1986 to Feburary 1997 in Chungnam National University Hospital were analyzed retrospectively. The results were as follows: 1)The mean age of recipients was 33.8 years and that of doners was 38.9 years. The male to female ratio of recipients was 2.5:1, and that of donors was 1.03:1 2) Living related donore(LRD) were 79.6% and living non-related donors were 20.3%. The HLA-identical donors(ID) in LRD were 18.7% and HLA-haploidentical donors(HID) were 61.0%. In living non-related donors(LNRD), mean matched HLA-AB antigens were 1.56 and mean matched HLA-DR antigens were 0.56. 3) The average 5-year patient survival fate was 94%, and average 5-year graft survival rate was 70%. The 5-year graft survival fate of HLA-ID was 100%, and those HLA-HID and LNR were 70% and 36% respectively. 4) Total 33 episodes of acute rejection were found in 45.8% of transplanted patients. The number of acute rejection episode did not show significant difference between LRD and LNRD(P > 0.05). There was no significant difference in MLC between two groups(p > 0.05). 5) In comparison between the 18 patients who lost their graft function in 5 years and 17 patients who are maintaining graft function for more than 5 years, MLC was significantly lower in patients with functioning graft than of patients with non-functioning graft (p < 0.05). The number of rejection episode was also lower in patients with functioning graft than that of the patients with non-functioning graft(p < 0.05). However, there were no significant difference in recepient and donor age and history of pre-transplantation donor specific transfusion between two groups. With the results above, we can speculate that adequate donor selection according to good matched HLA typing and low MLC is very important for graft survival in renal transplantation. Prevention and treatment of acute rejection in renal transplantation is also na important factor for graft survival.

Deodorization of pig slurry and characterization of bacterial diversity using 16S rDNA sequence analysis.

Hwang, Ok-Hwa,Raveendar, Sebastian,Kim, Young-Ju,Kim, Ji-Hun,Choi, Jung-Woo,Kim, Tae-Hun,Choi, Dong-Yoon,Jeon, Che Ok,Cho, Sung-Back,Lee, Kyung-Tai Microbiological Society of Korea 2014 The journal of microbiology Vol.52 No.11

<P>The concentration of major odor-causing compounds including phenols, indoles, short-chain fatty acids (SCFAs) and branched chain fatty acids (BCFAs) in response to the addition of powdered horse radish (PHR) and spent mushroom compost (SMC) was compared with control non-treated slurry (CNS) samples. A total of 97,465 rDNAs sequence reads were generated from three different samples (CNS, n = 2; PHR, n = 3; SMC, n = 3) using bar-coded pyrosequencing. The number of operational taxonomic units (OTUs) was lower in the PHR slurry compared with the other samples. A total of 11 phyla were observed in the slurry samples, while the phylogenetic analysis revealed that the slurry microbiome predominantly comprised members of the Bacteroidetes, Firmicutes, and Proteobacteria phyla. The rarefaction analysis showed the bacterial species richness varied among the treated samples. Overall, at the OTU level, 2,558 individual genera were classified, 276 genera were found among the three samples, and 1,832 additional genera were identified in the individual samples. A principal component analysis revealed the differences in microbial communities among the CNS, PHR, and SMC pig slurries. Correlation of the bacterial community structure with the Kyoto Encyclopedia of Genes and Genomes (KEGG) predicted pathways showed that the treatments altered the metabolic capabilities of the slurry microbiota. Overall, these results demonstrated that the PHR and S MC treatments significantly reduced the malodor compounds in pig slurry (P < 0.05).</P>

정신분열증에서 Global Field Power Measurement를 이용한 지표학적 시각유발전위 P100의 비대칭

황동진,이정태,한상익 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.6

Objects : The authors attempted to assess asymmetric brain activity to topographic visual evoked potential P100 determined by the Global Field Power Measurement in schizophrenia. Methods : The subjects, 40 normal controls and 35 schizophrenics, were assessed in the absolute amplitude of topographic VEP P100 by GFP. Results : There were not significant differences in asymmetric brain activity between normal controls and schizophrenics. But, in O₁,the absolute amplitude of schizophrenics was significantly greater than of normal controls. Conclusion : there results suggested that the schizophrenics may differ from normal controls not in asymmetricity(or laterality), but in brain activity.

자궁외임신의 임상적고찰

황태영,나용연,김종욱,박완석,이태형,이승호,정원영 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1

1983년 5월 28일 개원 아래 1985년 9월 30일까지 2년 4개월 동안 영남대학교 의과대학 부속병원 산부인과에 입원 가료한 바 있는 자궁외임신 88예를 대상으로 하여 임상적으로 조사, 관찰, 분석한 결과 다음과 같은 결론을 얻었다. 1. 자궁외임신 분만수에 대한 빈도는 1:22.2였다. 2. 빈발연령은 30~34세가 38.6%로 가장 많았으며, 25~34세는 67%였다. 3. 분만횟수와 임신중절 횟수가 증가 할 수록 자궁외임신의 빈도는 감소하는 경향을 보였다. 4. 기왕력은 골반염이 25%,복강경 불임술이 13.7%였으며 반복 자궁외임신은 6.8%였다. 5. 주요증상은 하복부 동통이 85.2%, 질출혈이 56.8%였으며 Scock증상은 3.4%였다. 6. 입원 당시 혈색소치는 8gm%이하인 경우가 6.8%, 10gm%이하가 37.5%였으며 복강내 출혈은 1,000ml이하가 53.4%였으며 2,000ml이상이 22.8%였다. 7. 뇨 임신반응 검사의 양성율은 파열균(78%) 및 유산균(63.3%)이 무상균(54.5%)에 비해 높았으나 통계적인 의의는 없었다. 8. 더글라스씨와 천자의 양성율은 75.9%였다. 9. 임신주수별로는 6~9주 사이가 48.9%로 가장 많았고 12주 이상이 15.9%였다. This study was undertaken for the clinical evaluation and statistical analysis on the 88 women with histopathogically confirmed ectopic pregnancies who were admitted and treated from grand opening on May-28,1983 to Sept.-30,1985. Incidence of ectopic pregnancy was 1 in 22.2 deliveries and the most common age group was in 30~34 years of age. There was tendency of decreasing incidencies as the gravidity, parity or artificial abortion were over 3. The most common etiologic factor was pelvic inflammatory disease and procedures for family planning were the next common. Common symptoms were lower abdominal pain(85.2%) and vaginal spotting(56.8%). At the admission, hemoglobin level under 10gm% were 44.3%. 69.5% of urine HCG tests were positive. Culdocentesis was positive only in 75.9%. Termination was frequent at 6~7 weeks of gestation mostly with rupture or abortion. Free blood in the abdominal cavity was averaged 1,224ml. 4 cases of clinicobiochemically suspected ectopic pregnancies with spontaneous regression were excluded, and there was no fatal case treated in hospital.

Characterization of Angiogenesis Inhibitor Effect of Green Tea Seed Extract

Hwang, Jae-Ho,Lee, Sung-Hoon,Rha, Sung-Ju,Yoon, Ho-Seop,Shin, Jin-Hyuk,Lee, Jin-Hee,Seo, Myeong-Jin,Kang, Kyeong-Wan,Han, Kyeong-Ho,Kim, Yong-Joo,Kho, Kang-Hee,Kim, Seon-Jae,Shin, Tai-Sun The Korean Society for Integrative Biology 2009 Animal cells and systems Vol.13 No.2

Green tea seed was extracted with absolute ethanol,and the green tea seed extract(GTSE)was subjected to assays for toxicity, antioxidant ability, angiogenesis inhibitory effects and cell adhesion, as well as western blotting, and an in vivo experiment against 4 high-ranking adult cancers in Korea. Our series of experimental data demonstrated that GTSE has an antioxidant ability superior to that of EGCG in the green tea leaf, and also exhibits a profound high tumor growth inhibitory activity on a variety of cancer cell lines, as well as nude mice infected with cancer cells. GTSE was identified as a natural anticancer compound showing excellent angiogenesis inhibition and cancer cell suppression abilities. Our preliminary observations also indicate that GTSE may be another potential source of natural dietary antioxidants and also may be applicable as a novel natural anticancer agent.