중합효소연쇄반응을 통해 확진되고 Atovaquone과 Azithromycin으로 치료한 Human Babesiosis 1예

윤기태,김연아,구남수,김준형,정세진,김홍정,송경호,최유경,신소연,김영근,김명수,박윤선,최준용,송영구,김준명 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

저자들은 국내에서 처음으로 중합효소연쇄반응 검사를 통하여 B. microti에 의한 인체 바베시오시를 진단하였으며, atovaquone과 azithromycin 병합요법을 사용하여 치유한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Human babesiosis is a tick-borne infectious disease caused by Babesia species. The clinical diagnosis is difficult because of nonspecific symptoms like flu. Rapid diagnosis of human babesiosis is microscopic examination in peripheral blood smear (Giemsa-stain) which reveals characteristic forms of an intracellular quadruplet parasite. But differentiation between Babesia microti and Plasmodium species can be quite difficult because of the morphologic similarity. We experienced a case of human babesiosis. The patient was a 62-year old Korean male who had been in New Jersey, U.S.A for 2 months. We initially diagnosed as malaria infection because the peripheral blood smear revealed intracellular single ring form organism. But the patient was not improved significantly by the treatment with chloroquine regimen. Finally we confirmed human babesiosis by polymerase chain reaction for Babesia microti. We treated the patient successfully with a regimen of atovaquone and azithromycin which has fewer adverse reactions than a regimen of clindamycin and quinine.

鹽化物 含有量에 따른 鐵筋腐食 및 콘크리트 强度特性에 관한 實驗的 硏究

김정섭,강연구,유덕룡,박광수 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.2

As reinforced concrete buildings have been large, high-storied and high perfomance supply of river sand and gravel is insufficient and sex sand and crushed gravels which have the problem in internal force and durability are used as substitute aggregates. The problems caused by the use of sea sand lower the durability of reinforced concrete building according t o the content of chloride and shellfishes and cause the problem of corrosion and neutralization of reinforcing rod. Therefore, this study analyzes the degree of corrosion and neutralization of reinforcing rod which are the causes of lowering durability of reinforced concrete buildings with the variable of chloride content through the experiment and obtains the following results. 1. As a result of experimenting river sand and sea sand by comparison, the corrosion can be found at reinforcing rod without using rust proof paint regardless of the covering depth from 60 days of age and especially, the extensive corrosion is occurred at the damaged reinforcing rod among the same rods. 2. As a result of neutralization experiment with river sand and sea sand, there is no response in neturalization till 60 days of age. 3. As a result of strength and non-destructive strength test with river sand and sea sand, it is found that the value of strength is increased more at the test specimen using sea sand than river sand and while the specimen using river sand shows increasing value of strength continuously based on 28 days of age, the specimen using sea sand shows the decrease in strengh as it has more chloride contents. It is thought that evaluation experiment and method of durability and security and countermeasure of durability according to age on the basis of the basic materials of this study should be conducted as future research task.

Changes in the Physicochemical Quality Characteristics of Cabbage Kimchi with respect to Storage Conditions

You, Su-Yeon,Yang, Ji-Su,Kim, Sung Hyun,Hwang, In Min Hindawi Limited 2017 Journal of food quality Vol.2017 No.-

<P>In this study, the changes in pH, organic acid content, acidity, and salinity of kimchi prepared at 0 days, stored 1–8 weeks at 4 and 10°C, and stored at room temperature for two days were analyzed. Organic acids content was analyzed by using analytical technique of high-performance liquid chromatography (HPLC). This method was also validated using quality assurance parameters of linearity, limits of detection and quantification (LOD and LOQ), precision, and spike recovery experiments. In the analysis of organic acids content (mg/kg), it was found that the kimchi stored for 1–8 weeks at 4 and 10°C showed gradual increase in the organic acids content during storage period. The order of organic acids was lactic acid > acetic acid > citric acid > malic acid > succinic acid > oxalic acid > fumaric acid. The pH values of kimchi stored at 4°C, 10°C, and 25°C were 4.1, 3.6–3.7, and 4.1, respectively.</P>

Molecular and Crystalline Structure of Rice Starches according to Processing Adaptability

Su-Yeon You,Lin-Lin Bian,Hyun-Jung Chung 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

아밀로오스 함량이 다른 쌀 전분의 분자 및 결정 구조와 이화학적 특성

유수연(Su-Yeon You),이은정(Eun-Jung Lee),정현정(Hyun-Jung Chung) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.6

국내에서 육종된 아밀로오스 함량이 다른 3가지 쌀 품종의 전분 특성을 살펴봄으로써 새로운 식품 소재의 개발을 위한 기초자료로 활용하고자 전분의 분자 및 결정 구조적 특성과 소화 특성을 조사하였다. 새고아미 전분은 다산1호나 새일미에 비해 아밀로오스 함량, 아밀로펙틴의 짧은 사슬(DP 6-12) 함량, 페이스팅 온도, RS 함량이 유의적으로 높았으며 반대로 아밀로오스의 중합도, 아밀로오스와 아밀로펙틴의 분자량, 아밀로펙틴의 B1사슬(DP 13-24), 상대적 결정성, 입자표면 결정성(1047/1022), 팽윤력, 호화 온도(T<SUP>o</SUP>, T<SUP>p</SUP>, T<SUP>c</SUP>), 호화 엔탈피, 페이스팅 점도(최고점도, 최종점도, 강하점도, 치반점도), RDS 함량, eGI값이 유의적으로 낮았다. 다산1호는 새일미에 비해 낮은 RDS 함량과 높은 SDS 함량을 보였다. 두 쌀 전분의 소화율의 차이는 분자 구조적 특성(아밀로오스 함량, 아밀로오스 중합도, 분자량, 아밀로펙틴 분자의 가지사슬 길이 분포)과 결정 구조적 특성(상대적 결정성, 1047/1022, 호화 온도와 엔탈피)의 차이에 근거하였다. 결과적으로 3가지 국내산 쌀 품종들의 전분 분자 및 결정 구조적 특성과 소화율 결과는 다양한 유형의 쌀을 이용한 가공제품 개발의 기초자료로 활용될 수 있을 것으로 기대된다. The in vitro digestibility and molecular and crystalline structures of rice starches (Seilmi, Dasan1, and Segoami) with differing amylose content were investigated. Segoami had the highest amylose content (30.9%), whereas Dasan1 had the lowest amylose content (21.2%). The molecular weight (M<SUB>w</SUB>) of amylose and amylopectin in Segoami was much lower than that of the other two rice starches. Segoami had the highest proportion (8.7%) of amylopectin short branch chains (DP 6-12) and the lowest proportion of B1 chains (DP 13-24). The relative crystallinity, intensity ratio of 1047-1022 cm<SUP>?1</SUP> (1047/1022) and gelatinization enthalpy followed the order: Segoami>Seilmi~Dasan1. Segoami showed substantially low pasting viscosity. Rapidly digestible starch (RDS), slowly digestible starch (SDS), and resistant starch (RS) contents showed the highest value in Seilmi, Dasan1, and Segoami, respectively. The expected glycemic index (eGI) of Segoami was lower than that of the other two rice starches. Overall results suggested that the digestibility of rice starch could be highly influenced by their molecular and crystalline structure.

YOLOv5를 이용한 개인정보 탐지 및 마스킹 알고리즘 구현

유수연 ( Su-yeon Yoo ),박유나 ( You-na Park ),서지혜 ( Ji-hye Seo ),오지연 ( Ji-yeon Oh ) 한국정보처리학회 2023 한국정보처리학회 학술대회논문집 Vol.30 No.2

미디어 공유 활성화에 따라 개인정보 노출의 위험성이 증가하고 있다. 본 논문에서는 YOLOv5를 통해 학습한 모델을 바탕으로 이미지에서 개인정보가 담긴 물체를 탐지하는 연구를 진행하였다. 모델로 탐지된 객체에는 광학 인식 기술(OCR)을 적용하여 객체 내의 텍스트 속 개인정보 영역을 마스킹 한다. 설계된 알고리즘은 여러 분야에 활용되어 개인정보에 대한 서비스 강화를 제공해 줄 수 있을 것으로 기대된다.

2·30대의 생활패턴을 반영한 영화관 애플리케이션 예매 UI 디자인 -개인의 스케줄에 따른 시간 우선 예매중심으로-

유수연 ( You Su Yeon ),최종훈 ( Choi Jong Hoon ) 한국기초조형학회 2017 기초조형학연구 Vol.18 No.5

본 연구의 목적은 모바일을 통해 영화를 가장 많이 예매하는 2·30대의 생활패턴을 반영한 새로운 영화 예매 구조를 제시하는 것이다. 최근 여가에 대한 사회적 관심의 증대에 따라 개인의 여가활동 투자가 증가했다. 가장 쉽게 접할 수 있는 여가활동 중 하나인 영화관람 또한 이러한 추세에 따라 관람객이 증가하고 있으며 영화관은 관람객의 만족감 증대를 위한 서비스 중 하나인 모바일 애플리케이션 예매방식을 이용 고객의 요구에 맞춰 발전시켜왔다. 하지만 현재 영화관 애플리케이션은 영화관, 날짜, 영화 세 가지의 항목을 선택하여 가장 효율적으로 예매를 할 수 있는 시스템을 유지하고 있다. 현재 영화관 애플리케이션 예매 구조는 대부분의 사용자가 어려움 없이 사용할 수 있어 범용성은 높다고 할 수 있지만 애플리케이션을 가장 많이 사용하는 2·30대의 라이프스타일이나 영화 예매 경험을 적극적으로 고려하지 못한 한계가 있다. 이에 본 연구는 영화 예매를 모바일로 가장 많이 하는 2·30대의 생활 패턴과 기존 영화관 애플리케이션을 분석하여 새롭게 제시할 영화 예매 UI을 위한 방향성을 제시하였다. 또한, 사용자 조사를 통해 영화 예매를 하는 상황을 관찰하고 인터뷰하여 분석하였다. 그 결과, 회사(학교 생활 중 여유 시간, 일과가 끝난 후, 심야·조조 시간, 일정 또는 약속이 취소됐을 때와 같이 개인의 하루 일과 및 시간을 중심으로 예매를 한다는 것을 발견하였다. 조사를 통해 그들의 일과 중 생기는 여유 시간을 설정하고 그 시간을 중심으로 영화를 예매할 수 있는 새로운 영화 예매 UI를 디자인하였다. 한 페이지에 영화 제목, 장소, 시간 등의 많은 정보를 한 번에 보여주는 것이 아닌, 자신이 선택한 시간에 따라서 선택적으로 정보를 볼 수 있게 구성한 것이다. 마지막으로 사용성 테스트를 통해 기존의 예매방식보다 새롭게 제안한 예매방식이 사용자들의 만족도와 사용성 측면에서 효과적이라는 결과를 도출하였다. The objective of this research is to propose a new movie reservation structure which applies the lifestyle patterns of individuals in the 20~30 age group. Due to the recent growth of social interest in leisure, the amount of time invest in leisure activities have increased. Following this trend, one of the most easily accessible leisure activities, which is going to the movies, is increasing and to meet the needs of these moviegoers, one of the methods movie theaters have developed is a mobile application that allows the audience to make reservations for movies. However, the current applications are maintaining a system which is incredibly efficient because it makes users only choose 3 things, which are the movie theater, date, movie, to book the movie. Due to its generality, the current structure of the movie reservation applications allow the majority of its users to book movies without much difficulty, however, there are limitations because it does not take into account the lifestyle or movie reservation experience of the individuals in their 20~30s, who use these applications the most. Therefore, this research proposes a direction for the movie reservation UI to be newly presented which will analyze the lifestyle patterns and existing movie theater applications of the 20~30 age group. Furthermore, the situation of making movie reservations was analyzed through user interviews. As a result, it was found out that they make reservations centered on their personal time, such as during their spare time during work or school, at the end of the day, when their schedule or appointment has been canceled. Through this investigation, we have designed a new movie reservation UI that enables users to set up the spare time they have during the day and during that time, make reservations for movies. Finally, through usability testing, we have deduced that the new movie reservation method proposed is more effective in terms of user satisfaction and usability than the pre-existing movie reservation methods.

Novel technology using AI-based MALDI-TOF/MS for prediction of spontaneous preterm delivery

( Su Ji Yang ),( Sang Hee Jung ),( Eun Hee Ahn ),( Ji Hyon Jang ),( You Jung Han ),( Hye Yeon Boo ),( Donggun Seo ),( Dong-chan Kim ),( Ji Hyae Lim ),( Hyun Mee Ryu ) 대한산부인과학회 2023 대한산부인과학회 학술대회 Vol.109 No.-

Odor Discrimination Using Neural Decoding of the Main Olfactory Bulb in Rats

You, Kyung-Jin,Ham, Hyoung Geol,Lee, Hyun Joo,Lang, Yiran,Im, Changkyun,Koh, Chin Su,Kim, Mi-Yeon,Shin, Hyung-Cheul,Shin, Hyun-Chool IEEE 2011 IEEE Transactions on Biomedical Engineering Vol.58 No.5

<P>This paper presents a novel method for inferring the odor based on neural activities observed from rats' main olfactory bulbs. Multichannel extracellular single unit recordings were done by microwire electrodes (tungsten, 50 μm, 32 channels) implanted in the mitral/tufted cell layers of the main olfactory bulb of anesthetized rats to obtain neural responses to various odors. Neural response as a key feature was measured by subtraction of neural firing rate before stimulus from after. For odor inference, we have developed a decoding method based on the maximum likelihood estimation. The results have shown that the average decoding accuracy is about 100.0%, 96.0%, 84.0%, and 100.0% with four rats, respectively.</P>

Feature Article : Stem Cell-Based Hepatic Differentiation for Cell Therapy of Liver Diseases

( Su Yeon An ),( Ji You Han ),( Jong Hoon Kim ) 한국조직공학과 재생의학회 2010 조직공학과 재생의학 Vol.7 No.1

Alternative liver disease treatment has been intensively studied because of the shortage of donated organs for transplantation and difficulty in culturing primary human hepatocytes for cell therapy. Human hepatocytes generated from pluripotent stem cells evolved as a promising treatment for liver disease as a means to overcome these limitations. Recently, embryonic stem cells (ESCs) and adult stem cells have been successfully differentiated into hepatocyte-like cells in vitro. However, it is difficult to compare the results of previous studies because of multiple paths of differentiation using many different standards, protocols, and animal models. Additionally, these cells are required to examine their functionality, their liver regenerating mechanism after appropriate animal models of liver disease prior to clinical trials. In this review paper, we summarize a variety of stem cells and their individual characteristics, which provide multiple opportunities for cell therapy treatment of liver disease patients. Furthermore, we present the current standard of applicable preclinical hepatocytes derived from stem cells such as experimental indicators for differentiation in vitro, confirmation of survival, engraftment, and function after cell transplantation into various preclinical liver disease animal models.