Design and Expression of Recombinant Antihypertensive Peptide Multimer Gene in Escherichia coli BL21

Sheng Qi Rao,Yu Jie Su,Jun Hua Li,Zhen Zhen Xu,Yan Jun Yang 한국미생물 · 생명공학회 2009 Journal of microbiology and biotechnology Vol.19 No.12

An Online Response System for Anomaly Traffic by Incremental Mining with Genetic Optimization

Su, Ming-Yang,Yeh, Sheng-Cheng The Korea Institute of Information and Commucation 2010 Journal of communications and networks Vol.12 No.4

A flooding attack, such as DoS or Worm, can be easily created or even downloaded from the Internet, thus, it is one of the main threats to servers on the Internet. This paper presents an online real-time network response system, which can determine whether a LAN is suffering from a flooding attack within a very short time unit. The detection engine of the system is based on the incremental mining of fuzzy association rules from network packets, in which membership functions of fuzzy variables are optimized by a genetic algorithm. The incremental mining approach makes the system suitable for detecting, and thus, responding to an attack in real-time. This system is evaluated by 47 flooding attacks, only one of which is missed, with no false positives occurring. The proposed online system belongs to anomaly detection, not misuse detection. Moreover, a mechanism for dynamic firewall updating is embedded in the proposed system for the function of eliminating suspicious connections when necessary.

Characterizations of Ag-catalyzed ZnO nanostructures prepared by vapor–solid mechanism

Su-Hua Yang,Pao-Chih Chen,Sheng-Yu Hong 한국물리학회 2009 Current Applied Physics Vol.9 No.2

This paper presents the synthesis and field emission characteristics of zinc oxide (ZnO) nanostructures grown on Ag-deposited Si substrate by using the vapor–solid (VS) mechanism. The morphology of the ZnO nanostructures was related to source and substrate temperatures. Nanowhiskers, nanotips and well-aligned nanorods were grown at substrate temperatures of 620, 650 and 680℃, respectively. A strong bluish-green photoluminescence (PL) indicated that the nanostructures had many surface defects correlated with oxygen vacancies. Field emission analyses showed that the turn-on fields of ZnO nanowhiskers, nanotips and well-aligned nanorods were 4.5, 5.8 and 6.1 V/㎛, respectively. The high emitter density and high aspect ratio of the well-aligned nanorods resulted in an enhancement in emission current density. Furthermore, the field emission stability of the well-aligned nanorods was better than that of the nanowhiskers and nanotips. The emission current densities of the ZnO nanowhiskers, nanotips and well-aligned nanorods, measured after continuous operation for 6 h, were approximately 2.05, 4.68 and 20.5 μA/㎠, respectively. This paper presents the synthesis and field emission characteristics of zinc oxide (ZnO) nanostructures grown on Ag-deposited Si substrate by using the vapor–solid (VS) mechanism. The morphology of the ZnO nanostructures was related to source and substrate temperatures. Nanowhiskers, nanotips and well-aligned nanorods were grown at substrate temperatures of 620, 650 and 680℃, respectively. A strong bluish-green photoluminescence (PL) indicated that the nanostructures had many surface defects correlated with oxygen vacancies. Field emission analyses showed that the turn-on fields of ZnO nanowhiskers, nanotips and well-aligned nanorods were 4.5, 5.8 and 6.1 V/㎛, respectively. The high emitter density and high aspect ratio of the well-aligned nanorods resulted in an enhancement in emission current density. Furthermore, the field emission stability of the well-aligned nanorods was better than that of the nanowhiskers and nanotips. The emission current densities of the ZnO nanowhiskers, nanotips and well-aligned nanorods, measured after continuous operation for 6 h, were approximately 2.05, 4.68 and 20.5 μA/㎠, respectively.

The Crucial Role of the Establishment of Computed Tomography Density Conversion Tables for Treating Brain or Head/Neck Tumors

Yang, Shu-Chin,Lo, Su-Hua,Shie, Li-Tsuen,Lee, Sung-Wei,Ho, Sheng-Yow Korean Society of Medical Physics 2021 의학물리 Vol.32 No.3

Purpose: The relationship between computed tomography (CT) number and electron density (ED) has been investigated in previous studies. However, the role of these measures for guiding cancer treatment remains unclear. Methods: The CT number was plotted against ED for different imaging protocols. The CT number was imported into ED tables for the Pinnacle treatment planning system (TPS) and was used to determine the effect on dose calculations. Conversion tables for radiation dose calculations were generated and subsequently monitored using a dosimeter to determine the effect of different CT scanning protocols and treatment sites. These tables were used to retrospectively recalculate the radiation therapy plans for 41 patients after an incorrect scanning protocol was inadvertently used. The gamma index was further used to assess the dose distribution, percentage dose difference (DD), and distance-to-agreement (DTA). Results: For densities <1.1 g/cm³, the standard deviation of the CT number was ±0.6% and the greatest variation was noted for brain protocol conditions. For densities >1.1 g/cm³, the standard deviation of the CT number was ±21.2% and the greatest variation occurred for the tube voltage and head and neck (H&N) protocol conditions. These findings suggest that the factors most affecting the CT number are the tube voltage and treatment site (brain and H&N). Gamma index analyses for the 41 retrospective clinical cases, as well as brain metastases and H&N tumors, showed gamma passing rates >90% and <90% for the passing criterion of 2%/2 and 1%/1 mm, respectively. Conclusions: The CT protocol should be carefully decided for TPS. The correct protocol should be used for the corresponding TPS based on the treatment site because this especially affects the dose distribution for brain metastases and H&N tumor recognition. Such steps could help reduce systematic errors.

Procedures of Diminishing Browning of the in Vitro Clonal Propagation of Pistacia vera L

Yang Liu,Shu-Chai Su,Ping-Sheng Leng 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

CHARACTERIZING THE TIME-FREQUENCY PROPERTIES OF THE 4 Hz QUASI-PERIODIC OSCILLATION AROUND THE BLACK HOLE X-ray BINARY XTE J1550-564

SU, YI-HAO,CHOU, YI,HU, CHIN-PING,YANG, TING-CHANG,HSIEH, HUNG-EN,CHUANG, PO-SHENG,LIN, CHING-PING,LIAO, NAI-HUI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

We present the results from analysis of the Hilbert-Huang transform (HHT) for the 4 Hz quasi-periodic oscillations (QPO) around the black hole X-ray binary XTE J1550-564. The resultant Hilbert spectra demonstrate that the QPO is composed of a series of intermittent signals appearing occasionally. From the analysis of the HHT, we further found the distribution of the lifetimes for the intermittent oscillations and the distribution for the time intervals with no significant signal (the break time). The mean lifetime is 1.45 s and 90% of the oscillation segments have lifetimes less than 3.1 s whereas the mean break time is 0.42 s and 90% of break times are less than 0.73 s. We conclude that the intermittent feature of the QPO could be explained by the Lense-Thirring precession model and rules out interpretations of continual frequency modulation.

LONG-TERM VARIATION STUDY OF CATACLYSMIC VARIABLES WITH PALOMAR TRANSIENT FACTORY

YANG, MICHAEL TING-CHANG,CHOU, YI,HU, CHIN-PING,SU, YI-HAO,HSIEH, HUNG-EN,LIN, CHING-PING,CHUANG, PO-SHENG,LIAO, NAI-HUI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

The Palomar Transient Factory is a project making use of a Schmidt 48 inch telescope located on the Palomar Mountain, which is surveying the sky with dynamical cadences. It was deployed in 2009 and the observed sky region is over 1200 square degrees. We have studied the long-term periodic variabilities of the known galactic cataclysmic variables (CVs). More than 20 of the sources had been found to have long term periodic signals, ranging from several tens of days to several hundreds of days. Some possible scenarios are proposed to explain the results, such as a magnetic field change of the companion star, precession of the accretion disk, triple systems and superoutburst cycles. Some preliminary discussion will be presented in this article.

Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

Yan-Su Guo,Dong-Xia Wu,Hong-Ran Wu,Shu-Yu Wu,Cheng Yang,Bin Li,Hui Bu,Yue-sheng Zhang,Chun-Yan Li 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.3

A subset of patients of amyotrophic lateral sclerosis (ALS) present with mutation of Cu/Zn superoxide dismutase 1 (SOD1), and such mutants caused an ALSlike disorder when expressed in rodents. These findings implicated SOD1 in ALS pathogenesis and made the transgenic animals a widely used ALS model. However, previous studies of these animals have focused largely on motor neuron damage. We report herein that the spinal cords of mice expressing a human SOD1 mutant (hSOD1-G93A), besides showing typical destruction of motor neurons and axons, exhibit significant damage in the sensory system, including Wallerian-like degeneration in axons of dorsal root and dorsal funiculus, and mitochondrial damage in dorsal root ganglia neurons. Thus, hSOD1-G93A mutation causes both motor and sensory neuropathies, and as such the disease developed in the transgenic mice very closely resembles human ALS. A subset of patients of amyotrophic lateral sclerosis (ALS) present with mutation of Cu/Zn superoxide dismutase 1 (SOD1), and such mutants caused an ALSlike disorder when expressed in rodents. These findings implicated SOD1 in ALS pathogenesis and made the transgenic animals a widely used ALS model. However, previous studies of these animals have focused largely on motor neuron damage. We report herein that the spinal cords of mice expressing a human SOD1 mutant (hSOD1-G93A), besides showing typical destruction of motor neurons and axons, exhibit significant damage in the sensory system, including Wallerian-like degeneration in axons of dorsal root and dorsal funiculus, and mitochondrial damage in dorsal root ganglia neurons. Thus, hSOD1-G93A mutation causes both motor and sensory neuropathies, and as such the disease developed in the transgenic mice very closely resembles human ALS.

Study on Crystallization Kinetics of Dynamically-Vulcanized PP/EPDM Blends

Bin Yang,Yan-Li Deng,Xia Ru,Ji-Bin Miao,Ming Cao,Jia-Sheng Qian,Li-Fen Su,Peng Chen,Jing-Wang Liu,La-Xia Wu,Tao Pang 한국고분자학회 2016 폴리머 Vol.40 No.4

Two types of β nucleating agents (β-NAs), aryl dicarboxylic acid amide (TMB-5) and diphenyl phthalate diamine (NT-C), were adopted to modify the polypropylene (PP)/ethylene propylene diene monomer (EPDM) blends, which were prepared by dynamic-vulcanization technology. Wide angle X-ray diffraction (WAXD) and differential scanning calorimetry (DSC) were used to study the crystallization kinetics of PP. Our results showed that the addition of β-NAs can considerably increase the crystallization temperature, and significantly decrease the spherulite size of β-PP (L300). The Jeziorny analysis showed there were ~82% and ~89% of relative crystallinity generated from the primary crystallization in the composites containing TMB-5 and NT-C, respectively. The crystallization half time (t0.5) showed that NT-C improved the overall crystallization rate more effectively than TMB-5. In addition, the peaks of the relative crystallization rate curves were shifted towards higher temperature by 14 and 9℃ with the addition of TMB-5 and NT-C, respectively.

An Online Response System for Anomaly Traffic by Incremental Mining with Genetic Optimization

Ming-Yang Su,Sheng-Cheng Yeh 한국통신학회 2010 Journal of communications and networks Vol.12 No.4

A flooding attack, such as DoS or Worm, can be easily created or even downloaded from the Internet, thus, it is one of the main threats to servers on the Internet. This paper presents an online real-time network response system, which can determine whether a LAN is suffering from a flooding attack within a very short time unit. The detection engine of the system is based on the incremental mining of fuzzy association rules from network packets,in which membership functions of fuzzy variables are optimized by a genetic algorithm. The incremental mining approach makes the system suitable for detecting, and thus, responding to an attack in real-time. This system is evaluated by 47 flooding attacks,only one of which is missed, with no false positives occurring. The proposed online system belongs to anomaly detection, not misuse detection. Moreover, a mechanism for dynamic firewall updating is embedded in the proposed system for the function of eliminating suspicious connections when necessary.