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      • SCOPUSKCI등재

        Study on Museum Digital Exhibition Mode and Industrialization of Intangible Cultural Heritage

        Bai, Jian-Song,Boo, Jong-Chul The Korea Institute of Information and Commucation 2011 Journal of information and communication convergen Vol.9 No.2

        Nowadays, most of exhibits are material antiquities while the exhibit of intangible cultural heritage is deficient and the form is less advanced which cannot meet the exhibition needs of digital times. This has resulted in insufficient display of intangible heritage's value which may not facilitate inherit and protection of intangible heritage, no other than protection mechanism of forming healthy industrialization. This article has established digital exhibition mode in museum about intangible cultural heritage by analysis on current museum and using mobile communication and augmented reality techniques. Discuss the mode in the layer integrating creative industry and mobile industry and provide practicable reference project of forming the healthy industrialization mechanism for protecting intangible heritage.

      • Lymph Node Ratio is More Predictive than Traditional Lymph Node Stratification in Lymph Node Positive Invasive Breast Cancer

        Bai, Lian-Song,Chen, Chuang,Gong, Yi-Ping,Wei, Wen,Tu, Yi,Yao, Feng,Li, Juan-Juan,Wang, Li-Jun,Sun, Sheng-Rong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Objective: To evaluate the relationships between lymph node ratio (LNR, the ratio of positive lymph nodes in excised axillary lymph nodes) and disease-free survival (DFS) by comparing with traditional absolute positive lymph node number (pN classification) for prediction of breast cancer (BC) progrnosis. Methods and Patients: We retrospectively reviewed patients who received comprehensive therapy in Department of Breast Surgery, Hubei Cancer Hospital, China from Jan 2002 to Dec 2006 (Group A), and Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, China from Jun 2008 to May 2012 (Group B). Patients were allocated to low-risk (${\leq}0.20$), intermediate-risk (> 0.20 but ${\leq}0.65$), high-risk (>0.65) groups by LNR. The primary endpoint was 5-DFS. Results: A total of 294 patients were included in our study. LNR was verified as a negative prognostic factor for DFS (P=0.002 in Group A, P<0.0001 in Group B). Then we found the effects of pN and LNR delamination on disease-free survival (DFS) had statistical significance (P=0.012 for pN and P=0.031 for LNR stratification in Group A, both of them P<0.001 in Group B). Compared to pN staging, LNR staging displayed superior performance in prognosis, the adjusted hazard ratio of recurrence being 2.07 (95%CI, 1.07 to 4.0) for intermediate risk group (P=0.030) and 2.44 (95%CI, 1.21 to 4.92) for high risk group (P=0.013) in Group A. Conclusions: LNR stratification proved an adverse prognostic factor of DFS in lymph nodes positive invasive BC using cut-off values 0.20 and 0.65, and was more predictive than traditional pN classification for 5-DFS.

      • 두경부 편평상피세포암 세포주에서 세포주기조절인자의 활성 및 이상 : 후두편평상피세포암에서 종양억제유전자 CDKN2 유전자의 발현이상

        송시연 ( Si Youn Song ),한태희 ( Tae Hee Han ),배창훈 ( Chang Hoon Bai ),김용대 ( Yong Dae Kim ),송계원 ( Kei Won Song ) 영남대학교 기초/임상의학연구소 2005 Yeungnam University Journal of Medicine Vol.22 No.2

        Background: Cyclin-dependent kinase (CDK) inhibitors are family of molecules that regulate the cell cycle. The CDKN2, a CDK4 inhibitor, also called p16, has been implicated in human tumorigenesis. The CDKN2 inhibits the cyclin/CDK complexes which regulate the transition from G1 to S phase of cell cycle. There is a previous report that homozygous deletion of CDKN2 region on chromosome 9p21 was detected frequently in astrocytoma, glioma and osteosarcoma, less frequently in lung cancer, leukemia and ovarian cancer, but not detected in colon cancer and neuroblastoma. However, little is known about the relationship between CDKN2 and laryngeal cancer. Therefore this study was initiated to investigate the role of CDKN2 in human laryngeal squamous cell carcinoma development.1) Materials and methods: We used 5 human laryngeal carcinoma cell lines whether they have deletions or losses of CDKN2 gene expression by DNA-PCR or RT-PCR, respectively. We examined 8 fresh frozen human laryngeal cancer tissues to detect the loss of heterozygosity (LOH) of CDKN2. PCR was performed by using microsatellite markers of short arm of human chromosome 9 (D9S126, D9S144, D9S156, D9S161, D9S162, D9S166, D9S171, D9S200 and D9SIFNA). For informative cases, allelic loss was scored if the signal of one allele was significantly decreased in tumor DNA when compared to the same allele in normal DNA. Results: The CDKN2 DNA deletion was observed in 3 cell lines. The CDKN2 mRNA expression was observed in only one cell line, which was very weak. LOH was detected in 7 cases (87.5%). Conclusion: These results suggest that CDKN2 plays a role in the carcinogenesis of human laryngeal squamous cell carcinoma.

      • KCI등재

        과배란유도 성숙난포액내의 Insulin-like Growth Factor-I (IGF-I) , Insulin-like Growth Factor Binding Protein-3 (IGFBP-3), Growth Hormone (GH) 및 Estradiol (E₂) 과의 상호관계

        송찬호,박기현,조동제,이용주,이병석,장경환,정창진,배상욱,김동현 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.3

        Recently, the ovary is known to be a center of paracrine and autocrine rehulating factors. IGF-I is a local regulator of follicular function and a potent stimulator of ovarian cell proliferation and differentiation, in synergy will the gonadotrophins, whilst GH may exert its effect by changing intra-ovarian IGF-I concentration. Inbiological fluids, IGFs are bound to specific, high affinity binding proteins(IGFBP). The IGFBPs are considered paracrine modulators of the action of IGF-I in the ovary. The aim of the study is to elucidate relationships amongst IGF-I, IGFBP-3, GH and estadiol in mature follicular fluids or serum. Thirty-six infertility patients who underwent ovulation induction program by GnRH agonist short or long protocol for in vitro fertilization (IVF) were examined to investigate the correlations amongst the concentration of IGF-I, IGFBP-3, GH and estradiol in follicular fluid or serum. These hormones were quantitatively analyzed by radioimmunoassay(RIA) or Immunoradiometric assay(IRMA). There were statistically significant correlations between the concentration of IGF-I and GH, IGFBP-3 in follicular fluid. Therefore, GH tends to increase IGF-I levels in follicular fluid and IGF-I may functions as an important regulator of IGFBP-3 synthesis in follicular fluid, but IGFBP-3 is not likely to be under the direct control of GH in follicular fluid.

      • Comparison of the in Vivo Activity of Two Protent Oxytocin Antagonsts on Utrine Activit in the Rat

        Bai, Young-Hoon,Song, Chang-Hun,Pak, Sok-Cheon 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

        목적: 비임신 백서에서 옥시토신 길항제인 Antag I과 TT-235의 체내 효과를 비교하기 위하여 시행되었다. 재료 및 방법: 모든 백서들은 약물을 주입하기 위한 목적으로 마취상태하에서 cannula를 jugular vein에 넣었다. 또한 자궁의 수축상태를 측정하기 위해 끝에 풍선이 달리고 안에 물을 채워넣은 또 다른 cannula를 자궁속에 넣었다. 자궁이 수축되는 수치는 10분간의 간격대로 측정되고 계산되었다. 각 옥시토신 길항제를 5㎍의 농도로 백서에 주입한 다음, 5분 후에 100 mU의 옥시토신을 넣고 이후 계속하여 1시간 간격으로 총 5시간 동안 옥시토신 주입을 계속하였다. 결과: 옥시토신 길항제인 Antag I과 TT-235를 주입하고 난 5분 후에 옥시토신을 주고 자궁의 수축상태를 살폈을 때 대조군에 비해 각각 77%와 92%가 억제되었다(P <.05). 2시간이 지난 후에 Antag I은 대조군에 비해 53% 정도의 자궁수축 억제효과를 보였는데 여전히 유효한 차이가 있었다(P <.05). 3시간대부터는 더 이상 대조군과의 차이를 보이지 않은 Antag I에 비해 TT-235는 5시간대까지 계속에서 대조군과 유효한 차이를 보이면서 자궁수축을 억제시켰다. 결론: 옥신토신에 의해 유발된 비임신성 백서의 자궁수축은 TT-235에 의한 억제 효과가 오랫동안 지속되었다. 체내에서의 이와 같은 효과는 산모에서 자궁 조기 진통을 억제하는데 이 약제가 효과적으로 적용될 수 있다는 것을 암시하였다.

      • Anomalous Pseudocapacitive Behavior of a Nanostructured, Mixed-Valent Manganese Oxide Film for Electrical Energy Storage

        Song, Min-Kyu,Cheng, Shuang,Chen, Haiyan,Qin, Wentao,Nam, Kyung-Wan,Xu, Shucheng,Yang, Xiao-Qing,Bongiorno, Angelo,Lee, Jangsoo,Bai, Jianming,Tyson, Trevor A.,Cho, Jaephil,Liu, Meilin American Chemical Society 2012 Nano letters Vol.12 No.7

        <P>While pseudocapacitors represent a promising option for electrical energy storage, the performance of the existing ones must be dramatically enhanced to meet today’s ever-increasing demands for many emerging applications. Here we report a nanostructured, mixed-valent manganese oxide film that exhibits anomalously high specific capacitance (∼2530 F/g of manganese oxide, measured at 0.61 A/g in a two-electrode configuration with loading of active materials ∼0.16 mg/cm<SUP>2</SUP>) while maintaining excellent power density and cycling life. The dramatic performance enhancement is attributed to its unique mixed-valence state with porous nanoarchitecture, which may facilitate rapid mass transport and enhance surface double-layer capacitance, while promoting facile redox reactions associated with charge storage by both Mn and O sites, as suggested by in situ X-ray absorption spectroscopy (XAS) and density functional theory calculations. The new charge storage mechanisms (in addition to redox reactions of cations) may offer critical insights to rational design of a new-generation energy storage devices.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2012/nalefd.2012.12.issue-7/nl300984y/production/images/medium/nl-2012-00984y_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl300984y'>ACS Electronic Supporting Info</A></P>

      • SCISCIESCOPUS

        The effect of annealing temperatures on surface properties, hydroxyapatite growth and cell behaviors of TiO<sub>2</sub> nanotubes

        Bai, Yu,Park, Il Song,Park, Hyeoung Ho,Lee, Min Ho,Bae, Tae Sung,Duncan, Warwick,Swain, Michael John Wiley Sons, Ltd. 2011 Surface and interface analysis Vol.43 No.6

        <P><B>Abstract</B></P><P>Well‐ordered TiO<SUB>2</SUB> nanotubes were prepared by the electrochemical anodization of titanium in an ethylene glycol electrolyte containing 1 wt% NH<SUB>4</SUB>F and 10 wt% H<SUB>2</SUB>O at 20 V for 20 min, followed by annealing. The surface morphology and crystal structure of the samples were examined as a function of the annealing temperature by field emission scanning electron microscopy (FE‐SEM) and X‐ray diffraction (XRD), respectively. Crystallization of the nanotubes to the anatase phase occurred at 450 °C, while rutile formation was observed at 600 °C. Disintegration of the nanotubes was observed at 600 °C and the structure vanished completely at 750 °C. Electrochemical corrosion studies showed that the annealed nanotubes exhibited higher corrosion resistance than the as‐formed nanotubes. The growth of hydroxyapatite on the different TiO<SUB>2</SUB> nanotubes was also investigated by soaking them in simulated body fluid (SBF). The results indicated that the tubes annealed to a mixture of anatase and rutile was clearly more efficient than that in their amorphous or plain anatase state. The <I>in vitro</I> cell response in terms of cell morphology and proliferation was evaluated using osteoblast cells. The highest cell activity was observed on the TiO<SUB>2</SUB> nanotubes annealed at 600 °C. Copyright © 2010 John Wiley & Sons, Ltd.</P>

      • 高等學校卒業者의 學校集團弗素溶液漱口意識에 關한 調査硏究

        송윤신,백대일,김종배 경복대학 2002 京福論叢 Vol.6 No.-

        본 연구는 대학 신입생의 학교집단불소용액수구지식의 수준을 확인하고, 대중을 대상으로 하는 학교집단불소용액수구교육의 목표와 내용을 확인할 목적으로 2002년도 경복대학 신입생 586명을 대상으로 구강보건의식에 관한 설문지를 사용하여 설문조사하고 분석한 결과 다음과 같은 결론을 얻었다. 1. 영구치아의 사용기간 인지율이 59.2% 이었다. 2. 영구치아를 발거하는 제1원인상병 인지율이 48.3% 이었다. 3. 학교집단불소용액수구사업의 치아우식예방효과 인지율 36.7% 이었다. 4. 치아우식증을 예방함으로서, 진료받을 필요를 감소시켜, 국민건강보험료를 인하시키면서도, 치아의 수명을 연장시킬 수 있다는 사실을 인지하고 있는 사람이 3분의 1에 불과하였다 5. 초등학교와 중등학교에서 학생들에게 학교집단불소용액수구사업에 관하여 교육하여야한다. 6. 농어촌 주민들에게도 사회교육의 일환으로 학교집단불소용액수구사업에 관하여 교육하여야 한다. To make confirm the knowledge level, educational goal and teaching contents of gargling with fluoride solution of school, an investigation was performed to examine and analysed, targeting in 586 college freshmen. Following results were obtained.(The results show as follows.) 1. Acknowledgement rate of retaining period of permanant teeth was 59.2%. 2. Acknowledgement rate of primaly etiology that causes extraction of permanant teeth was 48.3%. 3. Acknowledgement rate of preventive effect to dental caries through the plan of fluoride gargle in group was 36.7%. 4. 33.3% of people acknowledge the fact that prevention from dental caries car1 result in prolonging the life span of permanant teeth as well as reduction of national health insurance payment. The most important thing is to educate this plan to all the students in primary and middle school, and as a social education by extension to educate this plan to all the residents in farming and fishing villages.

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