주변 자원과의 연계를 통한 명심체험마을의 발전방향

이태순,김은영,윤성수,리신호 忠北大學校 農業科學硏究所 2012 農業科學硏究 Vol.28 No.2

The MYEONGSIM village located in Baekkok-myeon, Jincheon-gun, Chungcheongbuk-do, Korea has been developed the green tourism, farm stay and green rural experience project. Although the village has more varius advavtages such as gacilities and experience program than the other villages its tourists are gradually decreasing. In this thesis, specific development direction of the village will be proposed by the analysis of characteristics of tourists and SWOT analysis through understanding of characteristics of visitors and investigation of rural amenith resources

특발성 경련질환으로 오인된 원발성 부갑상선기능저하증 1례

신성하,최정영,김준기,고영춘,조상욱,김순호,임중규 全南大醫大 2001 전남의대학술지 Vol.37 No.1

소아청소년기에 치수치료를 받은 제1대구치의 술전 상태 조사

이순영,이경호,노홍석,정태성,김신 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

제1대구치는 막중한 역할을 함에도 불구하고, 청소년 이전에 건강을 상실하는 경우가 드물지 않다. 본 연구는 청소년기 이 전에 치수치료를 받게 된 제1대구치의 우식 및 수복 상태와 분포를 파악할 목적으로 시도되었다. 최근 5년간 부산대학교 치 과병원에서 치수치료를 받은 18세 이하 106명 환자의 135개 제1대구치를 대상으로 의무기록에 대한 조사를 시행하여 다음 과 같은 결과를 얻었다. 1. 평균 연령은 11.9세(남 11.5세, 여 12.5세)였고 유의한 성차를 보였으며(p<0.05), 악별로는 상악 47개, 하악 88개로 하악 치아가 더 많았다. 2. 치수 치료 전 치료 기왕력이 없는 치아는 74개, 치수 또는 수복 치료를 받은 치아는 61개였다. 그 중 재치수치료를 받게 된 경우는 22개로 치수절제술-치수절단술의 순이었으며, 단순 수복치료를 받았던 치아는 39개로 복합레진-아말감-GI- 인레이-수복물 탈락 후 미치료-열구전색 및 주조 전장관의 순이었다. 3. 병소 위치가 분류 가능한 73개의 병소 중에서는 근심면 병소가 22개, 교합면 혹은 협설면 병소 39개, 원심면 병소가 12 개를 차지하였다. In clinical dentistry, it is not difficult to meet the permanent first molars with severe coronal caries lesions in children or adolescents. The circumstances surrounding the first molars of children and adolescents are so immature and imperfect compared with those of adults. So we thought it significant to understand the status of these teeth at the moment of endodontic treatment and immediate cause of it. 106 patients with 135 permanent molars necessitating endodontic treatment in childhood and adolescence were included in this study, and the dental records and radiographs were examined. 1. The mean age was 11.9 year (male 11.5, female 12.5) and the result shows significant difference between gender(p<0.05). The mandibular teeth took more than half percentage than maxillary teeth. 2. Of 135 teeth, 45.2 percent of teeth had history of dental treatment previously and 16.3 percent of teeth showed necessity of re-endodontic treatment. 3. Of 73 teeth, 22 teeth had mesial-wall cavity causing endodontic treatment, 39 had occlusal cavity, and 12 had distal cavity.

느릅나무 뿌리껍질 성분의 유방염균에 대한 항균효과

신성진,윤민호,권순경,최우영 충남대학교 농업과학연구소 1999 농업과학연구 Vol.26 No.1

젖소 유방염 병원균에 대한 느릅나무 뿌리껍질(楡白皮)의 항균활성을 검토하기 위하여 용매분획별로 시험한 결과 일반적으로 chloroform 분획이 가장 효과적이었고 butanol 및 물분획의 활성은 낮았다. 유방염균을 Fleish extract broth에서 액체 배양할 경우에 chloroform 분획을 첨가하면 생육이 억제되었으며 특히 Staphylococcus aureus 및 Streptococcus sp. No. 12는 초기생육이 현저하게 저해되는 경향을 나타내었다. Hoechst 제약의 표준방법에 의한 MIC 시험에서도 유사한 결과를 얻었다. 또한 건조한 느릅나무의 뿌리껍질 100g을 물로 추출하여 겉보기 점도 77.5 cP, 최대흡수 파장 440㎚의 황갈색 수용성 점질물 4.500㎖를 회수할수 있었다. 이를 정제 건조한 무게는 32~35g이었으며, 탄수화물 함량이 61.0±1.0%, 단백질 8.0±0.2%로서 다당이 주성분이었다. 이상의 실험결과를 통해 유백피의 용매 추출분획물은 항균활성을 나타내는 성분으로, 그리고 수용성 점질물은 흡수성과 점성이 높은 다당류로서 염증 부위에 수렴작용을 나타내는 성분으로 결론지을 수 있었다. The methanolic extracts from the elm (Ulmus davidiana var japonica) root barks which have been known as an oriental medicine Eubackpie for the treatment of edema, ulcer and inflammation were examined for their bacteriocidal effects on mastitis pathogens of milk cows. The growth of the pathogenic bacteria such as Staphylococcus aureus and Streptococcus sp. No. 12 was markedly inhibited by the chloroform fraction among the extracts, and these antibacterial activities were also supported by MIC test. Water-soluble mucilage was obtained from the root barks with a yield of 36.8∼40.2% bf dry weight basis. This substance appeared to be a kind of polysaccharide with 61.0±1.0% carbohydrate content, and to have hygroscopic and astringent properties due to its high viscosity and water absorption.

島嶼地域의 特殊性과 開發必要性에 關한 硏究

申順浩 淸州大學校 1983 論文集 Vol.16 No.1

The population of our country is now over 40,000,000. If the population growth continues like this, will reach 50,000,000 by the turn of this century. Besides the fact that most-of the people in our country are crowding into Seoul and other big cities is a serious hindrance to balanced development of the land and the preservation of the national homogeneity. The development of the land up until the 1970s has brought about poverty and alienation of the rural communities and sea villages, because Government had the policy to stress only the best use of agglomeration economies. This phenomenon is appreared evident especially in (the remote) islands region as parts of the marginal areas. In this thesis, I aims at presenting a more reasonable direction of the national land development by grasping the real situation of the islands, that are alienated and have fallen behind. First of all the characteristics of those areas and the consciousness of the developmental problems of islands will be screened. And it will define the concept of island that is scarcely researched and furthermore present a general and comprehensive idea of the marginal areas and their characterstics, since those islands are the important part of marginal areas. Then it'll describe the pre-sent condition of the islands and their special circumstances. It'll also analyze such problems of these areas as transportation, the indirect social facilities, the circulation system, the sources and level of the islanders' incomes, their consciousness of ownership, and their living circumstances. But this is only a partial for the fundamental and basic research for the development of those islands. For a balanced development of the national land, it should be followed by more specific stratigies and techniques for the development of those areas.

부착단백질이 사람 치수세포의 부착 및 증식에 미치는 영향에 관한 연구

신영주,최호영,민병순,박상진,최기운 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

The purpose of this vitro study was to evaluate attachment and proliferation of human pulpal cells to the attachment glycoprotein-coated and non-coated culture dishes. Well known adhesive glycoproteins were used, such as type I collagen, type IV collagen, fibronectin, laminin, and vitronectin. Each adhesive glycoproteins applied onto the culture dishes. In this study, the protein coated and non-coated dishes were classified as each groups. Human pulpal cells cultured onto each culture dishes. After 90 minute, 4 hour and 24 hour incubation attached cells in each group were counted with hematocytometer for evaluation of the attachment of human pulpal cells. The configurations of attached human pulpal cells were done by SEM observation. The results as follows 1. After 90 minute incubation the score of attachment of human pulpal cells was best in laminin-coated group among groups. Then fibronectin, type IV collagen group were better, and allproteins were higher than control. 2. After 4 hour incubation the numbers of attachment of human pulpal cells were most in fibronectin coated group. 3. After 24 hour incubation all of adhesive glycoproteins showed high and similar attachment effect to human pulpal cells. 4. In SEM observation, fibronectin and type IV collagen groups showed well spreaded human pulpal cells, then laminin group was moderately spreaded, and vitronectin group was mildly spreaded as well as control group.

건강성인자원자에 있어서 Theophylline과 β_(2)-adrenergicagonists (Procaterol 및 Albuterol)의 약동학적 상호작용

신현택,권현명,김호순 숙명여자대학교 약학연구소 1998 약학논문집-숙명여자대학교 Vol.14 No.-

Theophylline and adrenergic β₂ -agonists are frequently used together in bronchial asthma and chronic obstructive pulmonary disease(COPD). Among the adrenergic β₂ -agonists, procaterol and albuterol are most frequently used with theophylline in Korean hospitals. The effect of procaterol and albuterol administration on pharmacokinetics of theophylline was studied in 11 normal healthy volunteers(6 males, 5 females). The theophylline clearances with and without /J-adrenergic agonist (procaterol) were 38.76 + 9.53 ml/kg/hr and 32.46 + 8.46 ml/kg/hr respectively, which were not statistically significant. Similar result was seen with albuterol. The values of AUC, T_(1/2), Ke and Vdss were not influenced by either procaterol or albuterol. Also, there was no significant change in cardiac output and heart rate. In conclusion, adrenergic β₂ -agonists (procaterol and albuterol) do not alter theophylline pharmacokinetics.

農村地域靑少年의 離農現象에 關한 硏究

申順浩 청주대학교 새마을연구소 1985 새마을硏究論文集 Vol.2 No.-

This paper aims at investigating the human resources that is be-fore anything most essential for the development of the rural area. The younger generation in rural area (especially farming area), even though they are not only the pillar of tomorrow but indispensable element in modernization and development of farming villages, has shown a sharp decrease. Accordingly, this paper intend to investigate First, the situation of steady decrease of the rural youths, Second, the causes of their out migration, Third, the way of thinking of rural inhabitants including younger generation, Fourth, the problems raised by the youths' out migration, Fifth, the countermeasures to deal with such a situation and the conclusion. The rapid industrialization since 1960's and the national program for land development pursuing the agglomeration economics to utmost have brought about a sharp decrease in the agricultural population, especially sharper decrease in the young people. Therefore, it is investigated that their ways of thinking because the causes of their out migration are well reveal in it. The detailed causes are seem to be as follows: 1) the meagerness of economic income bases. 2) the fact that there are more difficulties in farming than in engaging in the urban industry. 3) our social value system of looking-down on toward agriculture. 4) other constrained cultural, educational conditions in the rural area. The last chapter of this paper suggests the countermeasures to cope with such a situation and conclusion. The development of rural area is essential for the solution of urbanization, the balanced development of land and the national solidarity. In the light of the fact that such a development of farming area is the development from the below, the youths' settlement in the rural area is, more than anything else, important.

혈청 Cystatin C와 크레아티닌에 근거한 사구체 여과율의 비교

신호식,정연순,임학 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Background : In recent years, cystatin C (CysC) was proposed as a new marker for the glomerular filtration rate (GFR) due to a constant serum level. The present study analyzes whether creatinine based GFR prediction equations might be replaced by simple prediction equations based on serum concentrations of CysC in healthy young Korean men. Methods : We studied 145 apparently healthy young Korean men aged 19-29 years who visited The Armed Forces Yangju Hospital (Gyeonggi Province, Repulic of Korea) for health check from November 2008 to January 2009. Creatinine-based GFR was estimated by the formula of modified MDRD, Crockcroft Gault (CG). CysC-based GFR was estimated by the formula of Larsson, Hoek, Filler, Grubb, Le Bricon, Orebro-cyst (DAKO), Orebro-cyst (Gentian). Linear regression analysis was performed to evaluated correlations between GFR estimating formulae based upon serum CysC and serum creatinine. Results : Among CysC based GFR, Hoek's GFR is most similar with CG GFR and abbreviated MDRD GFR. Significant correlations were noted between CysC based GFR and creatinine based GFR. Conclusion : Creatinine based GFR prediction equations for healthy young Korean men might be replaced by simple prediction equations based on serum concentrations of CysC (especially Hoek' equation). 배경 : 혈청 cystatin C는 외부 요인에 영향을 받지 않고 일정한 값을 유지하므로 사구체 여과율에 대한 새로운 표지자로 제시되고 있다. 본 연구는 젊은 성인 남성에서 cystatin C에 근거한 사구체 여과율이 혈청 크레아티닌에 의한 사구체 여과율을 대체할 수 있는지 조사하였다. 방법 : 2008년11월부터 2009년1월까지 병원을 방문한 평균 연령 21세의 젊은 성인남성 145명을 대상으로 하였다. Cystatin C에 근거한 사구체 여과율은 Larsson, Hoek, Filler, Grubb, Le Bricon, Orebro-cyst (DAKO), Orebro-cyst (Gentian) 공식을 이용하였고 혈청 크레아티닌에 근거한 사구체 여과율은 변형된 MDRD, Crockcroft Gault 공식을 이용하여 산출하였다. Cystatin C에 근거한 사구체 여과율과 혈청 크레아티닌에 근거한 사구체 여과율은 선형 회귀분석을 통해서 연관 관계를 확인하였다 결과 : Cystatin C에 근거한 사구체 여과율 산출 공식중에서 Hoek 공식에 의한 사구체 여과율이 혈청 크레아티닌에 근거한 사구체 여과율과 의미있는 상관관계를 보였다. 결론 : 젊은 성인 남성에서 Cystatin C에 근거한 사구체 여과율은 혈청 크레아티닌에 의한 사구체 여과율을 대체할 수 있을 것으로 생각된다.

기능성 고등어 Fillet 제조 및 저장 중 품질 변화

신석우,장미순,권미애,서호준 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2004 한국식품저장유통학회지 Vol.11 No.1

고등어 fillet 제품의 저장 중 항산화의 기능성을 부여하고 고등어 특유의 비린내를 제거하기 위해 식염 외에 녹차, dillweed, 키토산, 올리고당, 생강을 첨가하여 진공포장한 후 5℃, 0℃, -20℃에 80일간 저장하면서 제품 특성을 조사하였다. 5℃에 저장한 고등어 fillet의 휘발성 염기질소 측정 결과는 이들 첨가물을 단독 또는 복합적으로 첨가한 시제품에서 2주 이내에 초기부패에 도달했고, 0℃에서는 4∼7주, -20℃에서는 저장 80일간 모든 시제품에서 신선도를 유지할 수 있었다. 이들 첨가물 가운데서도 키토산과 올리고당을 첨가한 시제품이 가장 신선도가 양호함을 알 수 있었다. 항산화성은 초기 과산화물가가 5.4∼7.8 meq/kg 이었던 것이 5℃ 저장시 35일째 15.7∼20.4 meq.kg, 0℃저장시 49일째 13.9∼18.4 meq/kg, -20℃저장시 80일째 11.6∼20.2 meq/kg으로 저온 일수록 산화속도가 늦었고 각각의 저장온도에서도 녹차, dillweed, 생강, 키토산, 올리고당을 첨가한 시제품에서 가장 산화속도가 늦었다. 친유성 갈색도는 -20℃에서 80일간 저장기간동안 거의 변화가 보이지 않았고 5℃와 0℃에서는 저장기간이 연장됨에 따라 갈색도는 증가하는 경향을 나타내었다. 저장 중 생균수 변화는 5℃와 0℃에서는 저장 80일째까지 생균수 변화는 보이지 않아 신선도 유지가 가능하였다. 관능검사 결과는 5℃저장시 14∼21일, 0℃저장시 28∼49일 점질물이나 산패취가 발생하여 상품적 가치를 상실하였고, -20℃에서는 80일간 저장기간 동안에 이들 변화는 나타나지 않았다. In oredr to endow mackerel fillet with antioxidant effect, functionality and remove fishy smell, chitosan, oligosaccaide, extracts of green tea, dill weed and ginger was used as soaking solution additives. Quality characteristics of soaked mackerel fillet(SMF) was investigated during storage temperature and time after vacuum packing with polyvinyl chloride film. From the results of VBN measurement, initial spoilage was showed within 2 or 3 weeks in SMF soaked with brine including extracts of green tea, herb and ginger at 5℃. In case of adding chitosan and oligosaccarides to the solution mentioned above, initial spoilage was found from 4 to 7 weeks, oxidation was reduced remarkably and SMF stored at -20℃ maintained the freshness during 80 days. Viable cell counts were reached to 108 for 3 weeks storage at 5 and 0℃. But no change of viable cell counts was founded at -20℃. The shelf-lifes of SMF according to 5, 0 and -20℃ storage temperatures were 2 to 3, 4 to 7 weeks and about 3 months, respectively.