Developmental Characteristics of SCNT Pig Embryos Knocked-out of Alpha-1,3-Galactosyltransferase Gene

Joo-Hyun Shim1,Mi-Rung Park,Byoung-Chul Yang,Yeoung-Gyu Ko,Keon Bong Oh,Jeong-Woong Lee,Jae-Seok Woo,Eung-Woo Park,Soo-Bong Park,Seongsoo Hwang 한국동물번식학회 2009 Reproductive & developmental biology Vol.33 No.3

가상현실 기법의 활용이 지식 성취도 향상에 미치는 효과 : 눈의 구조와 기능 내용을 중심으로 The Structure and Function of Eye

심규철,류수정,김현섭,김희수,박영철 한국과학교육학회 2003 한국과학교육학회지 Vol.23 No.1

The purpose of present study was to develop teaching-learning materials based virtual reality technology(VRT), and to examine the effect of it on the knowledge achievement of biology. Authoring tool of virtual reality(VR) was 3D Webmaster made in Superscape Ltd., United Kingdom. Educational materials was developed for the structure and function of eye of life field in the 10th science. It was learner-directed and interactive educational material using the Web-based and desktop VR. The result showed a meaningful improvement on the achievement. Using 3D VR shows the potential of available education media in the next generation as science teaching-aided material, which especially was efficient in the understanding and perception of abstract or difficult to direct experience learning contents.

전기자극이 성견 골결손부에 매식된 임플란트 주위조직의 치유에 미치는 영향

심재창,김영준,김옥수,정현주 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.2

Several experimental studies showed that the application of small amounts of electric current to bone stimulated osteogenesis at the site of the cathode and suggested that electrical currents promote osseointegration around dental implants. The purpose of this study was to determine the effect of direct microcurrent to endosseous titanium implants placed in bone defects. The right and left 2nd, 3rd and 4th mandibular premolars in ten mongrel dogs (15kg of weight) were extracted. One month later, Ti-machined screw type implants(3.8 mm diameter×8.5 mm length, AVANA�, Ostem) were placed in surgically created circumferential defect area(width 5mm, depth 4mm). The implants were divided into three groups according to the treatment modalities: Control group- implants without electrical stimulation; Experimental group I- implants with allogenic demineralized freeze dried bone grafting and Experimental group Ⅱ- implants allogenic demineralized freeze dried bone grafting and electric stimulation. The animals were sacrificed in the 4th and 8th week after implant placement and un-decalcified specimens were prepared for histological and histometrical evaluation of bone-implant contact ratio (BIC) and bone formation area ratio (BFA) in defect area. Some specimens at 8 weeks after implantation were used for removal torque testing. Histologically, there were connective tissue infiltration in the coronal part of defect area in control and the experimental group I. whereas direct bone contact was found in the experimental group Ⅱ without connective tissue invasion. Average BIC ratios at 4 weeks of healing were 60.1% in the experimental group Ⅱ, 47.4% in the experimental group I and 42.7% in the control. Average BIC ratios at 8 weeks after implantation were 67.6% in the experimental group Ⅱ, 55.9% in the experimental group I and 54,6% in the control. The average BFA ratio was 84.0% in the experimental group Ⅱ, 71.8% in the experimental group I and 58.8% in the control at 4 weeks, and the BFA ratios were 89.6% in the experimental group Ⅱ, 81.4% in the experimental group I and 70.5% in the control at 8 weeks after implantation. The experimental group Ⅱ showed also significantly greater BIC and BFA ratios compared to the control and the experimental group I (p<0.05). The removal torque values at 8 weeks after implantation were 56 Ncm in the experimental group Ⅱ, 49 Ncm in the experimental group I and 43 Ncm in the control. There was a statistically significant difference among 3 groups(p<0.05) . These results suggest that electrical stimulation improve and accelerate bone healing around endosseous titanium implants in bone defect.

Tetracycline 처리된 차폐막이 치은 섬유아세포에 미치는 영향

심재창,김영준,정현주,박병주 전남대학교 치과대학 1999 전남치대논문집 Vol.11 No.1

The purpose of this study was to evaluate the effect of tetracycline-treated e-PTFE membrane on the human gingival fibroblast attachment. To evaluate the cell attachment to membrane, the number of gingival fibroblast attached to e-PTFE membrane was counted by hemocytometer. Also the cytotoxic effect of tetracycline-treated e-PTFE membrane on human gingival fibroblast was measured by Wataha's MTT assay. After tetracycline-treated barrier membrane was exposed to culture media for 24 hours, cell attaachment to membrane and cytotoxic effect were measured. The results were as follows; As for cell proliferation rate, total cell number increase in both control group and tetracycline-treated e-PTFE membrane in course of time, but the cell numbers were decreased to half in tetracycline-treated barrier membrane as in the control group. In MTT assay, tetracycline-treated e-PTFE membrane showed moderate to weak cytotoxic effect compared to non-treated control. At the begining, tetracycline-treated, so was barrier membrane released abundant tetracycline and so decreased the number of cell attached barrier membrane, but not almost observed cellular activity inhibition on attached cell and as decreasing tetracycline-treated barrier membrane, the number of attached cell were increased. These results might suggest that tetracycline-treated e-PTFE membrane showed relatively low proliferation rate of attached cells, but weak cytotoxic effect. So it is suggested tetracycline-treated e-PTFE membrane could bind gingival connective tissue normally and the healing site could gain stability.

세계화 시대의 갈등 : 인권의 보편성과 상대성 Universality and Relativity of Human Rights

심현주 가톨릭대학교 인간학연구소 2006 인간연구 Vol.- No.10

An epoche of globalization, it is necessary to cooperation internationally for the protection of human rights. Through the increase in human flow and cultural exchange, the solidarity of civil society and the trade and the capital flow without a barrier on a global dimension, the globalization provides a sufficient condition for the proliferation of universal norm of human rights. At the same time it can generalize cultural difference or intensify the estrangement between core and peripheral culture. The reason of this is that the globalization is a phenomenon not simply on economical dimension, but on a complex dimension. In the respect that the globalization of human rights is related to the normal identity of a society, it leads to the sensitive response. The attempt to mediate between the discourse on human rights and the identity of individual culture is the phenomenon that is brought through the global economy and the mutual exchange of cultures. But the discorse on human rights must be free from political mechanics. First of all human rights has a concern in fundamental rights of individuality, and the trans-individual systems as a group, state and culture are only a means, which protects and promotes human rights. In order to the normalization of universal human rights in mechanics of globalization will this paper explore the conflicts in discourse about human rights and offer the schemes to overcome the conflicts.

세계화시대에 민족문화의 전망

沈玹朱 한국종교교육학회 2004 宗敎敎育學硏究 Vol.18 No.-

세계화는 한편으로 새로운 얼굴을 한 자본주의적 세계체제에 대한 불안과, 다른 한편으로는 전 인류의 연대적 실천에 대한 희망을 증가시킨다. 세계체제는 각 민족국가들의 정체성을 위협하는 결정적인 요소로 나타나고 있다. 이 위협에 대한 대항으로 민족의 정체성을 강화시키기 위한 전통문화운동이 활발하게 진행되고 있다. 시대의 변화를 맞고 있는 이 시점에서도 "전통"이 민족의 정체성을 담보할 수 있는 원동력인가? 또 "전통문화"가 현 세계체제에 맞설 수 있는 대항가치로서 유효한가? 라는 질문들은 이 시대의 향방을 정하는데 필수적이다. 본고는 현재 세계적으로 열풍을 일으키는 전통문화운동에 대한 성찰을 통해 인류사회를 위한 앞으로의 실천을 모색하고자 한다. Globalization increases on the one hand the precariousness by the capital world-system, that has a new face, on the other a hope of a cooperative praxis of the human being. The world-system comes in view as an decisive element, that threatens to the identity of every nation-state. But what as the resistance against that threat is actually spread out is only such as the tradition-culture-movement for the strengthening of the national identity. On this point are questions necessary for a direction of this epoch: is the "tradition" at this time of the epochal change as usual the driving force, that can take the national identity?, and is the "traditional culture" effective as the counter-value against the present world-system? This paper will explore a way for the praxis toward the future of the human society through the reflection on the present "tradition-culture-movement".

일개 대학 병원 종사자의 직종별 직무스트레스 수준

심미선,이강숙,홍현숙,이경숙 가톨릭대학교 산업의학센터 2000 韓國의 産業醫學 Vol.39 No.4

This study was carried out to find out the job stress factors, coping skill, stress symptom, stress results at a university hospital workers and to develop the goal of health promotion including stress management program. The data for job stress were collected from 61 doctors, 141 nurses, and 84 assistant-nurses in a university from March, 2000 to April, 2000. The results of the study were summarized as follows; 1.The stress scores from job internal factors were highest in doctor group for variety, in nurse group for significance, and assistant-nurse group for identity. 2.The hospital workers felt high stress from promotion and salary but there was no difference from professional groups. There were significant differences in interpersonal relation and organizational norm between nurse and assistant-nurse group and in job-home conflict between doctor and assistant-nurse group. 3.The stress symptoms such as anxiety, depression, and physical symptom were highest in assistant-nurse group. 4.The coping skill was highest in nurse group. 5.The result of stress such as work performance, job involvement and organization commitment was highest in nurse group. The intention to change the job was highest in doctor group. 6.The stress scores had positive correlations with various symptoms. In conclusion, the hospital workers felt high stress from job, interpersonal relation, and organizational norm. In order to relive the stress, the stress management program including to improve coping skill and strategy would be necessary.

뇌 동맥류 파열환자에서 안구운동 장애 : 증례 보고 Case Report

현용인,강재규,도종웅,정현태,심영기 최신의학사 1991 最新醫學 Vol.34 No.12

연구개의 이소성 뇌조직 - 1예 보고-

최현주,이연수,김영신,이교영,강창석,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.11

재생골재 생산방식의 차이에 따른 재생 굵은골재의 품질 특성에 관한 비교 연구

심종우,이문환,이세현,전현규 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study is intended for effective recycling of waste concrete. It analyzes the quality 0 the recycled coarse aggregate with production types. The conclusions of the study are as follows. 1. The recycled coarse aggregate which is produced through 5th Crushing Process (A-Type) shows the improvement in grading and particle shape, reduction in an absorption rate until 1.14% due to removal of attached the mortar and paste. Therefore, it satisfies the standards of KS F 2573(recycled aggregate for concrete) as the first grade. 2. The recycled coarse aggregate which is produced through 3rd Crushing Process(B-Type) is suited to the quality prOVlSlOns of the standards of KS F 2573, shows a 3.12% absorption rate that is second grade as recycled coarse aggregate. Based on the above results, it is possible to product first and second grade recycled coarse aggregates with production types. It is concluded that recycled coarse aggregate with production types can be used as aggregate within required conditions. And more researches are also needed to make recycled coarse aggregate better to use for concrete.