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급성심근경색에 병발한 심실중격결손증의 수술적 치료 1 예
조승연,정남식,윤정한,이웅구,정상만,신길자,홍승록 대한내과학회 1986 대한내과학회지 Vol.31 No.3
Perforalion of the ventricular septum is a rare but serious complication following myocardial infarction. It usually results in progressive intractable congestive heart failure and death; for that reason, it requires aggressive surgical intervention. Since the first report of surgical treatment for this serious complication by Cooley and colleagues, many reports decribed their complications. Here We report a case of postinfarction septal rupture treated by patch repair of the rupture and single coronary bypass graft.
Isolation and Characterization of Aniline-Degrading Bacteria
Kahng, Hyung-Yeel,Kim, Seung-Il,Woo, Mi-Jeong,Park, Yong-Keun,Lee, Yung-Nok The Microbiological Society of Korea 1992 미생물학회지 Vol.30 No.3
Six isolated strains degrading aniline were selected, identified and designated as pseudomonas putida K6, Pseudomonas acidovorans K82, Achromobacter gr. D. V. K24, Achromobacter xylosocidans K4, Moraxella sp. K21 and Moraxella sp. K22. All of them degraded 1000 ppm aniline completely within 30 to 36 hours. Most of these strains are resistant to antibiotics more than one, but Moraxella sp. has not any antibiotic marker tested. Most strains except for P. acidovorans K82 were shown to have resistance to the heavy metal ions such as Ni, Cu, Li, Ba, Co, etc. but not to Hg to which only P. putida K6 was resistant. M. sp. K21 was capable of degrading aniline to a maximum concentration of 2500 ppm without any repression. The incubation of the cell in limited pH ranges (4-8) had no great effect on aniline degradation. The addition of bactopeptone to the minimal media promoted the speed of aniline degradation, but the addition of glucose rather repressed the rate of aniline degradation. Through enzyme assay, A. gr. D. V. K 24 was shown to degrade aniline through artho-pathway and formed .betha.-ketoadipate as intermediate metabolite.
Endoscopic Spinal Surgery for Herniated Lumbar Discs
Shim, Young-Bo,Lee, Nok-Young,Huh, Seung-Ho,Ha, Sang-Soo,Yoon, Kang-Joan The Korean Neurosurgical Society 2007 Journal of Korean neurosurgical society Vol.41 No.4
Objective : So called "minimally invasive procedures" have evolved from chemonucleolysis, automated percutaneous discectomy, arthroscopic microdiscectomy that are mainly working within the confines of intradiscal space to transforaminal endoscopic technique to remove herniated epidural disc materials directly. The purpose of this study is to assess the result of endoscopic spinal surgery and favorable indication in the thoracolumbar spine. Methods : The records of 71 patients, 73 endoscopic procedures, were retrospectively analysed. Yeung Endoscopic Spine Surgery system with 7 mm working sleeve and $25^{\circ}$ viewing angle was used. The mean follow up period was 6 months [range, 3-9]. Results : Operated levels were from T12-L1 disc down to L5-L6 of S1 disc. Of 71 cases, 2 patients underwent transforaminal endoscopic surgery twice due to recurrence after initial operation. MacNab's criteria was used to assess the outcome. Favorable outcome, excellent of good, was seen in 78% [57 procedures] of the patients. Among 11 fair outcomes, only 1 procedure was followed by secondary open procedure, laminectomy with discectomy. Two of 5 poor outcomes were operated again by same procedure which resulted in fair outcomes. One patient with aggravated cauda equina syndrome remained poor and a lumbar fusion procedure was performed in other patient with poor outcome. There were 2 postoperative discitis that were treated with conservative care in one and anterior lumbar interbody fusion in the other. Conclusion : Evolving technology of mechanical, visual instrument enables minimal invasive procedure possible and effective. The transforaminal endoscopic spinal surgery can reach as high as T12-L1 disc level. The rate of favorable outcome is mid-range among reported endoscopic lumbar surgery series. Authors believe that the outcome will be better as cases accumulate and will be able to reach the fate of standard open microsurgery.
Cloning and Characterization of Two catA Genes in Acinetobacter lwoffii K24
CHUNG, YOUNG HO,HA, KWON-SOO,LEE, YUNG NOK,KIM, SEUNG IL,PARK, YOUNG-MOK,KIM, SOOHYUN,CHOI, JONG SOON,LEEM, SUN HEE,PARK, YONG KEUN 東亞大學校附設遺傳工學硏究所 1997 遺傳工學硏究 Vol.- No.6
Two novel type I catechol 1,2-dioxygenases inducible on aniline media were isolated from Acinetobacter lwoffii K24. Although the two purified enzymes, CDI₁and CDI₂, had similar intradiol cleavage activities, they showed different substrate specificities for catechol analogs, physicochemical properties, and amino acid sequences. Two catA genes, catA₁and catA₂, encoding by CDI₁ and CD I₂, respectively, were isolated from the A. lwoffii K24 genomic library by using colony hybridization and PCR. Two DNA fragments containing the catA1 and catA₂ genes were located on separate regions of the chromosome. They contained open reading frames encoding 33.4-and 30.4-kDa proteins. The amino acid sequences of the two proteins matched well with previously determined sequences. Interestingly, further analysis of the two DNA fragments revealed the locations of the catB and catC genes as well. Moreover, the DNA fragment containing catA₁ had a cluster of genes in the order catB₁-catC₁-catA₁ while the catB₂-catA₂-catC₂ arrangement was found in the catA₂ DNA fragment. These results may provide an explanation of the different substrate specificities and physicochemical properties of CDI₁ and CDI₂.