기종성 방광염 1예

마성권,나명윤,박종욱,고정희,염충호,김수완,김남호,최기철 全南大醫大 2001 전남의대학술지 Vol.37 No.2

정상 성인에서 수면박탈이 수면구조와 피로감에 미치는 영향

김완중,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

To identify the effects of sleep deprivation on sleep structure polysomnography was performed for 10healthy young adults. Visual analogue scale was also used to identify the effects of sleep deprivation on fatigue, mood, and sleepiness. The subjects were young adults, ranging in age from 21 to 26 years, without past or present histories of significant medical, neurological, or psychiatric illness as well as no current major sleep disturbances or parasomnias. After one adaptation night, each subject was recorded polysomnography in the sleep laboratory. Sleep records were analyzed according to the criteria of Rechtschaffen and Kales every 20 seconds, and tried paired-t-test and correlation. The results were summarized as follows. 1. After one night of total sleep deprivation, compared with the baseline, TST, stage 3, stage 4, and SWS were significanlty increased, and sleep latency was significantly shortened, and return to normal level after 3 nights of recovery. 2. The relative value(%) of stage 3, stage 4, and SWS were positive correlation between the baseline and the first recovery night. 3. Compared with the baseline, reaction time was significantly delayed in the first recovery night, and returned to normal level after 3 days of recovery. 4. The feeling of fatigue, mood, and sleepiness were significantly worsened in the first day after TSD, and returned to normal level after 3 days of recovery.

병원 내 환자에서 분리한 Klebsiella pneumoniae에서 광범위 β-lactamase의 분자생물학적 특성

위성현,김수영,김상일,김양리,유진홍,신완식,강문원 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.2

리튬이차전지용 부극재료로서 은분말에 대한 전기화학적 특성

박철완,도칠훈,문성인,윤문수 한국공업화학회 2003 응용화학 Vol.7 No.2

Silver powders have been extensively studied as an anode active material for lithium secondary batteries. In the present study, a unique attempt is made to develop silver negative electrode by slurry method, because the silver electrode is a good candidate to replace the commercial graphite electrode for lithium rechargeable batteries. Silver electrode was prepared and its electrochemical properties were characterized gradual increasing test state of charge (GISOC) analysis method. Charge-discharge performance indicates that the initial charge potential range of Li/Ag cells has showed similar behaviors compared with Li/Graphite system and the irreversible capacity facd is also higher than Li/Graphite system.

Staphylococcus aureus와 Coagulase-Negative Staphylococcus Species에 대한 Arbekacin의 시험관내 항균력

위성헌,강진한,허동호,이동건,김상일,김양리,최정현,김종현,유진흥,허재균,신완식,강문원 대한감염학회 2001 감염 Vol.33 No.4

Background : Most strains of methicillin-resistant Staphylococcus aureus (MRSA) now exhibit high-level resistance to various antibiotics, such as β -lactam antibiotics, aminoglycosides, macrolides, tetracyclines and quinolones. Recent reports describing the therapeutic failure of vancomycin for MRSA infections have arisen considerable concerns regarding the emergence of MRSA strains, which will require new therapeutic agents. Arbekacin, an aminoglycoside antibiotic, has antibacterial activity against both gram-positive and gram-negative bacteria and is stable in the presence of aminoglycoside inactivating enzymes produced by S. aureus. In this study, we compared the antibacterial activity of arbekacin with those of vancomycin, gentamicin, and amikacin against Staphylococcus aureus (S. aureus) and coagulase-negative staphylococci (CNS). Methods : For a collection of 549 S. aureus and 251 CNS isolates from three Catholic University Hospitals in Korea, minimum inhibitory concentrations (MICs) of arbekacin, vancomycin, amikacin and gentamicin were determined by agar dilution method using Mueller-Hinton agar according to NCCLS (National Committee for Clinical Laboratory Standards, USA)criteria. Results : Among 549 S. aureus isolates, 278 isolates were MRSA and 271 isolates were methicil sensitive S. aureus (MSSA). MIC50 & MIC90 of arbekacin against 549 S. aureus were 0.5 & 1 ㎍/mL, and MIC50 & MIC90 of vancomycin were 1 & 1 ㎍/mL. MIC of arbekacin against 549 S. aureus isolates ranges from 0.03 to 4 ㎍/mL, and MIC of vancomycin against 549 S. aureus ranges from 0.25 to 2 ㎍/mL. MIC90 of amikacin against 549 S. aureus was 32㎍/mL, and that of gentamicin was 128 ㎍/mL. MICs of amikacin and gentamicin were variable, ranging from 0.125 to 256, and otherwise arbekacin and vancomycin revealed relatively narrow range of MICs. MIC90 of arbekacin against 278 MRSA isolates & 271 MSSA were 1 & 0.5 ㎍/mL, and those of vancomycin against MRSA & MSSA were 1 & 1 ㎍/mL. MIC90 of amikacin against 278 MRSA & 271 MSSA isolates were 32 & 4 ㎍/mL, and that of gentamicin against MRSA & MSSA isolates were 128 & 32 ㎍/mL respectively. Among 251 CNS isolates, 122 isolates were MRCNS and 129 were MSCNS. MICSO & MIC90 of arbekacin against 251 CNS isolates were 0.25 & 2 ㎍/mL, and those of vancomycin were 1 & 2 ㎍/mL. MIC of arbekacin against 251 CNS isolates ranges from 0.015 to 32 ㎍/mL, and that of vancomycin isolates ranges from 0.25 to 2 ㎍/mL, MIC90 of arbekacin against 122 MRCNS & 129 MSCNS isolates were 2&0.3 ㎍/ML, and those of vancomycin were 2&s ㎍/ML. MIC90 of amikacin against 251 CNS isolates was 32 ㎍/ML, and that of gentamicin was 128 ㎍/ML for CNS. MIC90 of amikacin against 122 MRCNS & 129 MSCNS isolates were 128 & 8㎍/mL, and those of gentamicin ere 256 & 32 ㎍/mL. Conclusion : Considering above results, arbekacin can be useful agent against most strains of MRSA and MRCMS, which exhibit high-level resistance to amikacin and gentamicin. (Korea J Infect Dis 33:254~260, 2001)

Escherichia coli 패혈증 환자에 합병된 대칭적 하지 말단 괴사증 1예

남해성,유진홍,권순석,민준기,조현선,박민경,심병주,남유정,이지인,김진수,길욱현,조근종,신완식 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

We have encountered a rare case of symmetrical peripheral gangrene complicating Escherichia coli sepsis in a 47-years-old male. He was successfully treated with antibiotics, anticoagulants, and vasodilator. To our knowledge, this is the first report on symmetrical peripheral gangrene complicating E. coli sepsis in Korea.

충남대학교 부속동물병원에 의뢰된 개의 뇨결석 성분 분석 결과

노경완,송근호,조종기,박성준 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

A retrospective analysis was performed with 14 cases of canine urolithiasis examined at Laboratory of Clinical Pathology, College of Veterinary Medicine, Chungnam National University in the period between January 2005 and November 2005. The female (8 cases) had most occurrence about 14 cases. The Shih-tzu (8 cases), Poodle (4 cases) had higher incidences than other breeds. Canine urolithiasis occurred from 1 year 3 months to 7 years 6 months, but the most prevalence age was 3 years. The major mineral component of calculi was calcium oxalate (64.28%) and struvite(21.44%).

Diffuse Large B-cell Lymphomas의 예후인자로서의 혈청 β2-microglobulin

어완규,신성훈 KOSIN UNIVERSITY COLLEGE OF MEDICINE 2006 高神大學校 醫學部 論文集 Vol.21 No.1

Background: This study was undertaken to see whether serum β2-microglobulin (B2M) could be used as a prognostic factor or not in patients with previously untreated diffuse large B-cell lymphoma (DLBCL). Methods: One hundred and forty-six consecutive patients with previously untreated DLBCL were participated in this study between 1995 and 2004. Serum B2M was measured by a radioimmunoassay in pretreatment serum samples of patients with DLBCL. Patients were then treated with CHOP or equivalent regimens with or without radiotherapy. Results: Serum B2M was available in 127 out of 146 patients enrolled. The median age was 54 years (15-80). Serum B2M levels greater than 2.5 mg/L were found in 27/127 (21.3%) patients. Higher serum levels were associated with old age, high serum LDH, poor performance status, increased number of extranodal site(s), advanced stage, constitutional symptom, bone marrow involvement, and high International Prognostic Index (P=0.001, 0.000, 0.000. 0.024, 0.000, 0.010, 0.040, and 0.000, respectively). The complete response rate was 40.7% vs. 68.0% for patients with serum B2M levels greater than 2.5 mg/L vs. control (P=0.010). The median overall survival was 11 months vs. 74 months for patients with serum B2M levels greater than 2.5 mg/L vs. control (P=0.0000). Conclusions: Serum B2M level was a good predictor of complete response and overall survival in patients with previously untreated DLBCL and could be used as a prognostic factor.

개에 있어서 심장사상충증을 동반한 창상성 횡격막 허니아의 수술적 치료 1례

조승혁,임영환,손정민,노경완,박창식,전무형,김명철,송근호,정성목 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

A 7-month old. castrated male Shih-tzu dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with history of depression. dyspnea. mild scale. tachypnea. exercise intolerance and severe leanness. On physical examination. cardiac arrhythmias was heard and heart worm ELISA test was positive. Microfilaria was found on the direct blood smear. Survey radiographs showed loss of diaphragmatic line and cardiac silhouette. displacement of lung fields and presence of gas filled intestines in the thoracic cavity. Rib fracture and pelvic fracture with callus formation were found incidentally. On the basis of physical examination and radiographic findings. it was diagnosed as traumatic diaphragmatic hernia and heart worm disease. Herniorrhaphy was performed. Postoperatively. it was treated for heart worm disease and scale. There is no evidence of recurrence of diaphragmatic hernia and heart worm disease over 1 year.

웹카메라를 이용한 천체사진촬영에 관한 연구

류성룡,황완기 금오공과대학교 2006 論文集 Vol.27 No.-

Recently, CCD cameras has been widely adoped for astronomical photography. CCD is more sensitive than photographic film and has the advantage of e,ISY digital image processing. In this paper, we have used a PC web camera instead of expensive commercial astronomical CCD camera for astrophotography. The images of the bright objects such as Moon, Sun, and Jupiter have been easily obtained by an ordinary web camera. A Vesta Pro web camera have been modified by Steve Chamber method for long exposed astrophotography. The thermal noise of the CCD has been dramatically decreased by cooling the CCD with a Peltier device. The initial images of the globular clusters M3 and M13 have been obtained with the modified Vesta Pro~SC web camera. We could obtain the bright pictures correspond to the long exposed photography by digitally adding the several short exposed frames. The noise of the long exposed frames were greatly reduced compared to the short exposed frames. In conclusion, we have shown that the web camera can be used for astrophography very economically in middle schools and high schools which have telescopes with limited tracking ability.