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      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

        김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

        Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

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        알쯔하이머형 치매환자 뇌파의 시공간적 패턴분석 : Karhunen-Loeve 방법을 통한 뇌파분석의 임상적용을 위한 예비연구

        고효진,김형래,김대진,김수용,박성종 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

        연구목적: 뇌파의 시공간적 패턴분석(spatio-temporal pattern analysis)방법을 이용하여 알쯔하이머형 치매의 진단 특히 초기 치매환자의 진단에 대한 예비연구를 하고자 하였다. 방법: 알쯔하이머형 치매환자 10명과 정상대조군 10명을 대상으로 하여 Karhunen-Loeve 분해법을 이용한 시공간적 패턴분석을 통하여 비교하였다. 결과: 첫째, 세가지 주요패턴 중 가장 많은 빈도를 보인 으뜸패턴에서 알쯔하이머형 치매환자는 좌우측 비대 칭성이 정상대조군에 비해 뚜렷해지는 형태를 보였다. 둘째, 으뜸패턴을 비교하여 뇌의 각 부분에 대한 차이를 보았을 때 알쯔하이머형 치매환자는 대조군에 비해 주로 좌측 두정부와 측두엽 부위에서 고유값의 유의한 차이가 있었다. 셋째, 으뜸패턴 전개계수의 Fourier amplitued spectrum 분석을 통하여 알쯔하이머형 치매환자 10명중 6명에서 상당히 큰 진폭의 상승부분을 관찰할 수 있었으며 정상대조군에서는 이러한 진폭의 이상소견이 관찰되지 않았다. 결론: 본 연구의 결과는 알쯔하이머형 치매으 병태생리적 위치가 좌측 측두-두정엽에 있음을 시사하였으며 앞으로 시공간적 패턴분석 방법이 알쯔하이머형 치매환자의 진단에 유용하게 사용될 수 있도록 추후연구가 필요할 것으로 생각하였다. Objectives: We introduce a novel analysis method of spatio-temporal pattern analysis of EEG. Using it, we presents a results discriminating severe Alzheimer's disease patients from normal subjects. Methods: To the groups of 10 Alzheimer's disease patients and 10 normal aged subjects, we applied the Karhunen-Loeve decomposition method and observed their principal patterns and time-varying dynamics. Results: First, there was a first primaty pattern of the eigenvector in Alzheimer's disease patients that showed opposite polarities at the left and the right hemispheric regions. Second, the Alzheimer's disease patients had significantly different average values of the eigenvector at the left parieto-temporal area than the normal controls did. Third, some Alzheimer's disease patients had one, coherent frequency component in the Fourier amplitude spectrum of the first pattern expansion coefficient. Conclusions: Our results suggest that the pathophysiologic site of Alzheimer's dementia may be left temporo-parietal area in brain and further studies need to evaluate whether the spatio-temoral pattern analysis could be used to diagnose Alzheimer's dementia patients.

      • 군산산단 주변의 주요 악취물질 규명 및 저감을 위한 기초조사

        김성천,박성순,박태선,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-

        We examined odor concentration during two seasons(fall and winter). The results were as follows : We confirmed the concentration of H₂S, MM, DMS were high. And especially DMA, TMA and i-PA were detected highly in fall and odor indices of those were more than 1, so we confirmed those materials were odor origin materials, but did not detected those materials in winter. The concentrations of n-butylicacid and MEK in VOCs in winter were higher than fall. Therefore we think that examination odor materials with temperature are very important. The concentrations of DEA, i-BA and methanol, methyl ethyl ketone(MEK), methyl cyclo hexane, toluene, and stylene were not exceed minimum sensitive concentration, but those are presumed odor potential material. The odor origin materials in Kunsan industrial complex in fall were H₂S, DMA, TMA, i-PA, n-butylicacid, and the odor potential material were MMA, sec-BA, methyl ethyl ketone(MEK). The odor origin materials in Kunsan industrial complex in winter were H₂S, MM, DMS, n-butylicacid, and the odor potential material were DEA, i-BA, methyl ethyl ketone(MEK), methyl cyclohexane. The dilute magnification in Kunsan industrial complex in fall were examined DMA 10, TMA 3 and total of those was 13, and that in winter were examined H₂S 3, MM 2, DMS 2 and total of those was 8. But the regulation of boundary of factory in industrial complex is <20. The number of odor intensity(1.0 - 2.0) were that H₂S was one in fall and four in winter and therefore that of total five. And the number of odor intensity(1.0 - 2.0) of TMA was four in fall. Generally a civil appeal occur that odor intensity is more than 2.0.

      • 매립지 침출수내의 Ca^2+, Fe^2+,3+, 휴믹물질 동반제거에 관한 연구

        김지태,고명욱,배성렬 漢陽大學校 工學技術硏究所 2002 工學技術論文集 Vol.11 No.-

        탄산칼슘(CaCO_3) 결정화 석출과 수산화철(Fe(OH)_3)의 결정화 석출을 위해 반회분식 장치를 이용하였으며, 반응온도는 25±2℃로 유지하였고 교반속도는 40∼80rpm으로 교반하였다. 매립 침출수내에 함유되어져 있는 Ca^2+와 Fe^2+, Fe^3+를 응집 침전물로 결정화한 후, 활성탄에 흡착시켰다. 휴믹물질을 금속 이온 물질과 배위 결합시켜 함께 제거할 수 있었다. 침출수 처리의 적정pH 범위는 9∼10이었고, 약 90%이상의 Ca^2+, 휴믹물질이 동반제거됨을 알 수 있다. 그러나 Fenton 산화처리 이후에 활성탄 흡착에 의한 Fe^2+,3+, 휴믹물질의 동반제거에 있어서 충분한 처리방법이 되지 못함을 관찰할 수 있다. Batch reactor was used in this study for treating CaCO_3 and Fe(OH)_3, temperature was maintained at 25±2℃ and stirring speed was 40∼80rpm. Ionic metals such as Ca^2+, Fe^2+ and Fe^3+ in leachate were precipitated and adsorbed by activated carbon. Subsequently ionic metals and humic substances that combined with Ca^2+, Fe^2+ and Fe^3+ are removed. The removal efficiency of humic substances was varied with pH value. At the pH 9∼10 range in the treated leachate, Ca^2+, humic substances was removed over 90%. but removal of Fe^2+,3+, humic substances didn't show that the efficient treatment was absorbed by activated carbon after Fenton treat.

      • Eisenmenger씨 증후군 산모의 긴박 제왕절개술시 전신마취 경험

        김준,고우석,정종달,유병식,임경준,소금영,안태훈,한승룡 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

        Eisenmenger's syndrome describes a situation in which the left-to-right intracardiac shunt is reversed as a result of increased pulmonary vascular resistance. The patients with Eisenmenger's syndrome are poorly tolerated and markedly increased maternal mortality to 30 - 50% during pregnancy, Physiological change of pregnancy decreases systemic vascular resistance that further aggravates the bi-directional or left shunt associated with Eisemnenger's syndrome. We report a case of 37 weeks a pregnant woman with an urgent cesarean section under general anesthesia for preterm labor. She was a pregnant patient with Eisenmenger's syndrome and did not receive antenatal care during pregnancy. Anesthesia was induced with ketamine-midazolam-fentanyl and maintained with ketamine-midazolam. The patient was ventilated with 100% O₂. Blood pressure was maintained with intravenous phenylephrine, crystalloid solution, and blood. Phenylephhne was used to maintain systemic vascular resistance (SVR). Even though the patient was carried rapid and adequate medical management, the patient was transferred to the ICU in an intubated state and died 2 days after surgery. We conclude that the parturients with Eisenmenger's syndrome require more regular, careful antenatal care, monitoring, and adequate management.

      • KCI등재
      • KCI등재

        건설업 규모별 안전관리 활성화 방안

        고성석,이종빈,김종욱 한국안전학회 2004 한국안전학회지 Vol.19 No.1

        After the IMF financial crisis, a lot of risks in construction industry have been increased gradually with the expansion of construction industry widely, higher stories of building, and the expansion of the underground space and excavation work. These risks are bringing out constriction accidents such as the death, the injury of worker and so on, not so much as it would be effected the corporation's image. In spite of these situations, many constriction industries still maintain the wrong methods and riot try to decrease construction accidents. Decently, we should focus on the fact that larger construction industries have been endeavoring to decrease the accidents in construction site and the safety management system of the larger constriction also is being good, on the other hand, the condition of the work in the case of smaller construction industries is very poor, construction company have a particular safety management system but it has a difference according to the construction magnitude, construction companies have a particular safety management system but it has a difference depending on the construction magnitude. Thus, we need to study the smaller construction safety management to decrease the construction accident according to the construction magnitude. Therefore, this study will suggest the developed way of construction safety management by the comparison and analysis from the difference between the higher and the smaller construction industries.

      • 전주산업단지 및 주변지역 VOCs 및 악취물질 모니터링(Ⅱ)

        박성순,김용문,박비오,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-

        Important main odorous componds and VOCs(volatile organic componds) possibly emitted from the Jeon-Ju Industrial Sites were identified and measured in amount through making air sampling over Jeon-Ju Industrial Sites and analyzing them with the sate of the art analytical instrument. Sampling sites were chosen 8 points by considering the industrial characteristics for the 1,2 Industrial Sites and 2 points for the 3 Industrial. Site Sampling times were two times, the first was September. 2002, the second was November. 2002, and the third February. 2003. Canister sampling units and polyester bags were used to collect 6 liters air samples during 1hour or 3 minutes for VOCs and polyester bags were used to sample 10∼50 liters of air for 3 minutes depending on analytic characteristics of odor compounds. The important main VOCs were measured as ahexane(11.7ppb), 2-methyl(10.3ppb), methyl acetate(9.3ppb), methyl cyclopentane(7.2ppb), dichloromethane(5.2ppb), toluene(4.9ppb), m,p-xylene(4.8ppb), methanol(4.7ppb), M.E.K(methyl ethyl ketone : 3.9ppb), ethyl benzene(3.6ppb), n-undecane(3.6ppb), o-xylene(2.6ppb), 2-methyl hexane(2.6ppb), n-butylacetate(2.4ppb) as in oder of average concentration for the Industrial Sites. In the case of measurement ingredient for sulfur compounds, appeared by MM (N.d - 1.67ppb), DMS(N.d - 1.32ppb), DMDS(N.d - 1.76ppb). NH_(3) was measured as below the detection limit of the instrument. Among aldehydes, form aldehyde, acetaldehyde were detected very highly as 0.1- 1ppm over all the Industrial Sites.

      • KCI등재
      • KCI등재

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