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배남규,문석재,임동윤,권오성 대한본초학회 1997 大韓本草學會誌 Vol.12 No.2
The present study was attempted to investigate the cardiovascular effects of Cheonmagudeumg-Eum (CMGDE), which is known to be one of chinese medical prescriptions used in treatment of hypertension, in the anesthetized rats and to clarify the mechanism of its pharmacological action, making use of its water extract. 1. CMGDE (5-45 ㎎/㎏), given into a femoral vein of the rat, produced a dose-dependent hypotensive and bradycardic responses while even much larger doses of it (10-90 ㎎/㎏), given into the rectum, did induced negligible hypotensive responses. 2. CMGDE-induced depressor responses were inhibited greatly by pretreatment with phentolamine (an adrenergic α-receptor antagonist), but not by pretreatment with atropine (an antimuscarinic agent) and chlorisondamine (an autonomic ganglionic blocker). 3. Pressor responses evoked by intravenous norepinephrine were attenuated significantly by pretreatment of CMGDE-infusion with a rate of 45㎎/㎏/20min. 4. In the rat aortic strips, phenylephrine (an adrenergic α1-receptor agonist) and high potassium (a membrane depolarizing agent) caused potent contractile responses, respectively. However, in the presence of CMGDE (2㎎/㎖), the contractile responses of phenylephrine (10-5M) and high potassium (5.6×10 exp (-2)M) were markedly inhibited. Taken together, these experimental results suggest strongly that Cheonmagudeung-Eum may cause the hypotensive responses in the anesthetized normotensive rat, indicating that this cardiovascular effects of CMGDE is likely due to the blockade of adrenergic α-receptors without cholinergic effects.
항에리트로포에틴 (Anti-erythropoietin) 항체에 의한 진성 적혈구계 무형성증 (Pure Red Cell Aplasia) 2예
양재석 ( Jae Seok Yang ),이정은 ( Jung Eun Lee ),박동준 ( Dong Jun Park ),성은영 ( Eun Young Seong ),주권욱 ( Kwon Wook Joo ),안규리 ( Cu Rie Ahn ),한진석 ( Jin Suk Han ),김성권 ( Suhng Gwon Kim ),조한익 ( Han Ik Cho ),이정상 ( Ju 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.5
배석환(Seok-Hwan Bae),박명철(Myung-Chul Park),유재상(Jae-Sang You),김용권(Yong-Gwon Kim),류철호(Cheul-Ho Ryoo),오동현(Dong-Hyun Oh) 대한방사선과학회(구 대한방사선기술학회) 2023 방사선기술과학 Vol.46 No.2
The purpose of this study was to examine the association between the shapes and colors of emergency exit symbols, magnetic field warning symbols, and radiation zone symbols used in hospitals for staff and patient safety and their effects on cognitive memory. The hippocampal region’s signal intensity(SI) was analyzed using fMRI. The Symbol 2 (1.75±0.54) with a green background had the highest signal intensity (SI) for emergency exits, according to the findings. The black symbol 2 (1.60±0.51) with a yellow background had the highest signal intensity (SI) for the magnetic field warning symbol, followed by the black symbol 1 (1.59±0.65) with an orange background. The black symbol 2 (1.59±0.59) with a yellow background and the black symbol 3 (1.58±0.52) with an orange background had the low signal intensity with slight differences as for the radiation zone symbols. In conclusion, it was determined that the signal intensity of the black symbol with a yellow background was the highest in the magnetic field area and radiation area. This implies that symbols with a high signal intensity (SI) must be utilized intensively. To ensure that the correct meaning of the symbols is communicated in the future, they must also be utilized regularly and continually in disaster safety education.