1-Arylpyrrole로부터 9-Arylcarbazole의 합성

朴유미,金寅植,李龍均,成大東,金東賢,金倫瑛,鄭大一 東亞大學校附設基礎科學硏究所 1997 基礎科學硏究論文集 Vol.14 No.1

Carbazoles were discovered in anthracene oil of coal tar, and are the parent structure of a number of heterocyclic compounds. Much attention has been paid to carbazole derivatives recently as the materials for semiconductors and photoconductive compounds. Many conventional methods for synthesis of carbazoles were known such as Grabe-Ullmann methods and the Tauber methods. In the course of the investigation for the synthesis of pyrrole derivatives 3. We have found the formation of 9-arylcarbazoles 4 under refluxing glacial acetic acid. Thus we report the results here.

방사선조사가 백서의 치주조직에 미치는 영향에 관한 실험적 연구

박대희,이상래 大韓口腔顎顔面 放射線學會 1986 Imaging Science in Dentistry Vol.16 No.1

It is known that radiation therapy is a kind of treatment choices of the maxillofacial tumors. This study is designed to investigate the irradiation effects on rat's periodontal tissues as functional tissues which relate to tooth-support, hard tissue formation and destruction. 20 rats (Sprague-Dowley branch, male) were devided into control group of 4 and experimental groupe of 16. Experimental group was singly exposed to Co-60 irradiation with 10 Gy in the head and neck region. Animals were sacrificed on 2 bays, 1 week, 2 weeks and 3 weeks after the irradiation. The specimens were observed by histopathological examination employing H-E stain, van-Gieson stain and PA-ACH fluorescent stain. The results were as follows: 1. Cementoblasts and osteoblasts were gradually lost and rearranged along the external surfaces of the cementum and alveolar bone, but osteoclasts were almost not affected. 2. The cell numbers of the periodontal ligament were decreased due to the cellular atrophy and degeneration, but recovered almost normally on the 3rd week after irradiation. 3. The collagen fibers within the periodontal ligament were irregularly oriented, became finer and decreased in number. 4. The vessels of the periodontal ligament were decreased at the initial stage but increased again on the 2nd week after irradiation, and the hemorrhagic appearances, occurred within the tissues, due to the arterial destruction, were lasted until 3 weeks after irradiation. 5. The glycogen within the periodontal ligament was gradually and stored in the matrices of the cemental side on the 1st week after irradiation, but recovered almost normally on the 3rd week after irradiation.

大學敎育의 評價方法 改善方案에 關한 硏究

李揆成,權相善,金大倫,朴哉林,林鍾吉,朴英淑 新羅大學校 1982 論文集 Vol.12 No.-

The present study aims to develop of evaluation method for college education. This study consiste of two parts: to identify the corelation between the freshmen's scores of pre-test for entrance examination and their scores of freshmen's year, and to make suggestions for the improvement of evaluation method in college on the basis of the former study results. Seen from the above mentioned aspects of this study, this study has meanings in its seek for a rational curriculum improvement and in its research of the pilot curriculum which presupposes the alleged system of limited graduation quota. This research which is conducted by above mentioned purpose andmeanings can be summerized as follows; 1) The freshmen's mean score of the-pre-test of college entrance examination is 192. 38. Among the departments of natural scienc attained the most higher score(204.22). and department of arts and gymnastics 162. 02 which is below average score. 2) In the achivements of the freshmn'e year the departments of natural sciences obtained the best results, followed by the departments of arts and gymnastics, education, and cultural aciences in oder. 3) There is no corelation between the pre-test scores of college entrance examination and the college achivement results. 4) The mean scores of the major and teaching subjects geneally increas as they go up into the advanced school years. 5) Each department has their own method of evaluation. 6) Teaching syllabus is asked to be presented whit the direction of clas, contents, purpose, and specific items of evaluation. 7) Achivements of college work must be evaluated by the normal distribution curve with the facts about specific factors of the study and students group taken into consideration.

관상정맥동과의 연결이 없는 좌상대정맥의 CT 소견 : 1예 보고 case report

백상현,박재성,이혜경,홍현숙,김대호,조준희,박성진,차장규 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

A persistent left superior vena cava (PLSVC) is the most common thoracic venous anomaly. It is a persistent remnant of a vessel that is present as a counterpart of normal right-sided superior vena cava(SVC) in early embryological development but normally disappears later. Its diagnosis can be confirmed by many noninvasive and invasive tests, or it is incidentally diagnosed at insertion into the left subclavian or jugular vein or thoracic surgery. If it is not associated with other congenital cardiac anomalies, it is usually asymptomatic and hemodynamically insignificant. We describe the chest radiograph and CT findings of bilateral SVC with drainage to left superior intercostal vein, hemiazygos, azygos vein and right SVC, and no connection of coronary sinus.

재무제표 구조 개선에 관한 연구 : 국제비교 중심으로

이대선,고완석,유청을,송기신,박성환 서강대학교 경영학연구원 2002 서강경영논총 Vol.13 No.1

초과이익할인모형의 이익추정기간과 터미널가치에 관한 실증연구

이대선,박성환,이진욱 서강대학교 경영학연구원 2003 서강경영논총 Vol.14 No.1

Wavelet based Fast Numerical Solutions of Elliptic Differential Equations

김대경,박상웅 한양대학교 이학기술연구소 1999 이학기술연구지 Vol.1 No.-

본 논문에서는 근사이론과 웨이블렛 분해를 이용하여 타원형 편미분방정식에 대한 고속수치 해법을 연구하였다. 특히 타원형 편미분방정식에 대한 웨이블렛의 수학적 분석을 통하여 실질적으로 빠른 수치해법을 수행할 수 있는 전처리 행열자를 유도하였다. 실제 수치모의실험을 위하여 주기적 경계조건을 갖는 간단한 모델을 사용하였다. The objective of this paper is to study of a fast numerical sollution method of elliptic differential equations based on approximation theory and wavelet decompositions. For the numerical simulation of this study, we consider a simple model of elliptic differential equations with periodic boundary conditions and empoly orthogonal wavelets.

Swanson의 주의력결핍 장애척도의 한국판 표준화

이종범,박성찬,정성덕,김진성,서완석,배대석,주열 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.2

연구목적 : 한국판 Swanson의 주의력 결핍 장애 척도(이하 SNAP)의 신뢰도와 타당도를 검증하고, 이를 국내 실정에서 주의력결핍 과잉행동장애 환자를 선별할 수 있는 평가용 도구로서 적합한지 여부와 연구에 사용할 수 있는지를 알아보고자 하였다. 방 법 : 1998년 7월 1일부터 2001년 9월 30일까지 영남대학교 의료원 신경정신과 외래를 방문한 주의력결핍 과잉행동장애 환자 392명과 정상대조군 432명을 대상으로 SNAP을 시행하였다. 결 과 : 남녀 간의 SNAP 척도 점수비교에서, 환자군에서는 유의한 차이가 없었으나 정상 대조군에서는 남자가 유의하게 높게 나타났다(p<.01 ∼ .001). 검사-재검사 신뢰도 검증에서 신뢰도 계수는 각 하위 척도에서 .85에서 .92로 모두 만족할 만큼 높았다(p<.05). 내적일관성에 의한 신뢰도 검증에서 정상 및 환자군에서 각 하위척도별로 Cronbach α값이 .80(p.05)이상으로 나타났고, 반분신뢰도는 정상 및 환자군에서 각 하위척도별로 0.731에서 .866사이였다(p<.05). 주의결핍장애 평가 척도-가정관(Attention Deficit Disorder Evaluation Scale-Home Version) 및 소아기 집중력 문제 척도(Childhood Attentin Problem Scale)와의 준거 타당도는 ADHD 환자군에서 .342에서 .713사이였고(p<.05), 정상 대조군에서 .551에서 .789였다(p<.05). 요인분석을 해 본 결과 본 척도는 3개의 요인으로 분류되었는데, 부주의(inattention) 요인, 충동성/과잉행동(impulsivity/hyperactivity)요인, 또래 관계(peer interaction)요인으로 구분되었다. 본 척도가 정상인과 환자를 감별할 수 있는 척도인가를 알아보기 위한 감별 타당도 검사를 해본 결과 87.5%를 분류하여 높게 나타났다. 환자와 정상인을 구분하는 점수인 절단점은 표준편차 1.5를 절단점으로 잡을 때 이는 백분율로 93percentile에 해당하는 점수로서 각 소척도 점수에서 남자(0.98∼1.65)와 여자(0.64∼1.38)의 절단점이 다르게 나타났으며 남자가 높게 나타났다. 결 론 : 이상의 결과에서 볼 때 한국판 SNAP 평가 척도의 신뢰도와 타당도가 입증되었고 환자를 판별하는 능력이 우수하여 향후 ADHD 연구에 유용한 도구로 사료된다. Objectives : The purpose of this study was to examine reliability and validity of Swanson's attention deficit disorder sacale(SNAP). Method : SNAP was administered to 432 elementary school students and 392 patients who were diagnosed as attention deficit hyperactivity disorder in Yeungnam university hospital from 1998 July to 2001 September. Results : In the reliability test, the test-retest reliability coefficient was significantly high and that of inattention was 0.85, that of impulsivity was 0.90, that of hyperactivity was 0.90 and that of peer interaction was 0.92(p<.05). In the reliability test by internal consistency, the Cronbach α coefficient was above 0.80 at each subscale in both patients and normal control group(p<.05). The split-half reliability coefficient by first-second half method showed high correlation and those of each scales were from 0.731 to 0.866 in both patients and normal control group(p<.05). The criterion validity of SNAP with Attention Deficit Disorder Evaluation Scale-Home Version(ADDES-HA) and Childhood Attention Problem Scale(CAP) scale was from 0.342 to 0.713 in patients group, from 0.551 to 0.789 in normal control group(p<0.05). The discriminant ability between ADHD and normal subjects by SNAP was 87.5%. Conclusion : In this point of view, SNAP scale showed high reliability and validity in applying to Korean subjects and was proved to be useful screening tool for attention deficit hyperactivity disorder reserch.

브로콜리 줄기의 callus배양 및 항노화 효과

박태진 ․ 이상민 ․ 조준환 ․ 남수호․ 신주은 ․ 김대환 ․ 이인순 ․ 박흠대 대구대학교 산업기술연구소 2018 産業技術硏究 Vol.29 No.2

Broccoli (Brassica oleracea var. italica) is well known of excellent antioxidant food so that we researched on its anti-aging and callus differentiation from the tissue of broccoli stem by MS medium with exo-phytohormone as IAA, kinetin. The functional materials of callus tissue were extracted with water and 70% EtOH after 16 days progressed callus formation. As a result, callus differentiation and formation were showed higher efficiency at B5 condition medium (0.1 mg/L IAA, 0.4 mg/L). The callus cultured on B3, B6 and B7 medium were observed the reaction of enzymatic browning to callus tissue. The anti-aging effect on the extract was experiment with DPPH radical scavenging and catalase(CAT). The activity of DPPH radical scavenging was showed high value in water extract of B1, B6, B8, B9 and was increased depending on sample concentration. However, in case of the extract of 70% EtOH, DPPH activity was showed different effect depending on the sample kind. CAT activity was found the highest enzyme unit in the extract of natural broccoli and B1(no add exo-phytohormone). It is to express that a broccoli itself is great food for anti-aging. Therefore, callus formation of broccoli considers having no economic efficiency to do development of anti-aging product.

신원방우황청심원의 뇌허혈 및 중추신경계에 미치는 영향

조태순,이선미,이은방,조성익,김용기,신대희,박대규 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

Abstract-In order to investigate pharmacological properties of New Wonbang Woohwangchungsimwon Pill(NSCH) and Wonbang Woohwangchungsimwon Pill (SCH), the effects of NSCH and SCH on cerebral ischemia and central nervous system were compared. Cerebral ischemia insult was performed using unilateral carotid artery occlusion in mongolian gerbils. The histological observations showed preventive effects of NSCH and SCH treatments with ischemia-induced brain damage. The ATP in brain tissue was decreased in vehicle-treated ischemic gerbils. This decrease was prevented by SCH treatment. In contrast to what was seen with ATP, lipid peroxide were elevated in vehicle-treated ischemic gerbils. This elevation was inhibited by NSCH and SCH treatments. While NSCH and SCH had no effects on the hexobarbital-induced sleeping time, they prevented the seizures induced by eletric shock and strychnine. NSCH and SCH showed sedative effect in rotarod and spontaneous activity test. Furthermore, NSCH and SCH showed anti-stress effect. Our findings suggest that the pharmacological profiles of NSCH on cerebral ischemia and central nervous system are similar to those of SCH.