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Phytochemical Studies of Phyllanthus debilis
K.S.Chandrashekar,D.Satyanarayana,A.B.Joshi,E.V.S.Subrahmanyam 한국생약학회 2004 Natural Product Sciences Vol.10 No.3
Two Lignans Phyllanthin and Hypophyllanthin, and a steroid b-sitosterol has been isolated from the leaves of Phyllanthus debilis and their structures were established by spectral analysis and direct comparison with authentic samples. This is the first report of occurrence of these compound from P.debilis.
P. S. Kumar,G. V. V. J. Rao,R. S. Kumar,P. E. Satyanarayana 경남대학교 기초과학연구소 2024 Nonlinear Functional Analysis and Applications Vol.29 No.1
In this paper, we prove the existence of common fixed point for a pair of $\alpha-\eta-\psi$-Geraghty contraction type maps in complete metric spaces using new type of $\alpha$-admissible. These results extend and generalize some of the previously known results.
Rao, M. Mohana,Satyanarayana, S.,Kumar, S. Vinay,Jain, H.S. The Korean Institute of Electrical Engineers 2010 Journal of Electrical Engineering & Technology Vol.5 No.4
Gas-insulated transmission lines (GITL) are valued as technological solutions in hydro-power stations due to their enormous power handling capabilities. The performance of GITL is a function of the size of metallic particles inside the gas-insulated chamber. Electrostatic field (E-field) enhancement is a common phenomenon in gas-insulated lines due to these metallic particles. In this study, the E-field enhancement factor is calculated by considering metallic particles at various locations in the gas-insulated line/bus section, such as high-tension (HT) conductor, high-voltage shields, support insulator, and inner surface of grounded enclosure. For this purpose, a two-dimensional model based on finite element (FE) method is developed. The length of the metallic particle is in the range of 1 to 10 mm while the diameter is between 1 to 3 mm. E-field enhancement is also computed for various particle configurations of the gas-insulated system, with focus on dielectric coating made of epoxy on HT conductor and inner surface of grounded enclosure.
M. Mohana Rao,S. Satyanarayana,S. Vinay Kumar,H.S. Jain 대한전기학회 2010 Journal of Electrical Engineering & Technology Vol.5 No.4
Gas-insulated transmission lines (GITL) are valued as technological solutions in hydropower stations due to their enormous power handling capabilities. The performance of GITL is a function of the size of metallic particles inside the gas-insulated chamber. Electrostatic field (E-field) enhancement is a common phenomenon in gas-insulated lines due to these metallic particles. In this study, the E-field enhancement factor is calculated by considering metallic particles at various locations in the gas-insulated line/bus section, such as high-tension (HT) conductor, high-voltage shields, support insulator, and inner surface of grounded enclosure. For this purpose, a two-dimensional model based on finite element (FE) method is developed. The length of the metallic particle is in the range of 1 to 10 ㎜ while the diameter is between 1 to 3 ㎜. E-field enhancement is also computed for various particle configurations of the gas-insulated system, with focus on dielectric coating made of epoxy on HT conductor and inner surface of grounded enclosure.
K. Anitha,S. Mohana Lakshmi,S. V. Satyanarayana 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.4
The leguminous plants Canavalia ensiformis (CE) and Canavalia gladiata (CG) though not eaten frequently but possess some desirable potential but widely used for lowering the glucose level in folkloric medicine. The current research aims for the fractionation of total triterpenoids (TT) and total flavonoid (TF) of ethanolic seed extract of Canavalia species shows significant hypoglycemic, hypolipidemic effect in High-fat diet +Streptozotocin induced rats and to explore the mechanism. Two fractions of Canavalia ensiformis (CE) total triterpenoids (CETT), total flavonoids (CETF) and two fractions of Canavalia gladiata (CG) total triterpenoids (CGTT), total flavonoids (CGTF) were subjected to Phytopharmacognostic study. Glibenclamide (5 mg/kg) was used as a standard drug. The body weight of control group increased significantly from 206 ± 0.98 to 240 ± 0.97 after STZ treated at 21st day diabetic rats showed significant decrease in body weight from 220 ± 0.78 to 168 ± 0.34. HbA1C level was raised in diabetic group 12.2% meanwhile treated groups summarized deceased levels. Elevated level of blood glucose > 386 mg/dl was considered as severe diabetic and further Diabetic induced rats, when treated with these four fractions of extracts, decreased the blood glucose level and serum levels of TC, TG, LDL has also lowered in treated rats than in diabetic rats and increased levels of HDL. The antioxidant indexes SOD, GSH showed decreased levels and LPx, NO levels elevated in diabetic group were also evaluated Histopathological effect of Pancreas of CETT, CETF, CGTT, CGTF has been studied The results obtained from this study showed significant hypoglycemic, hypolipidemic and antioxidant potential.
Mustafa, Bakheit,Satyanarayana, S. Korean Chemical Society 2010 대한화학회지 Vol.54 No.6
L이 urea, acetamide, semicrabazide, formamide 인 thiocyanato (L) Cobaloxime 착물을 합성하고 특성을 규명하였다. Thiocyanato(L)cobaloximes (SCNCo$(DH)_2$(L))과 benzyl (aquo) cobaloxime $PhCH_2Co(DH)_2(OH_2)$를 반응시켜 일반 분자식 $PhCH_2Co(DH)_2SCNCo(DH_2)(L)$를 갖는 일련의 thiocyanato로 연결된 dicobaloximes 생성물을 얻었다. Thiocyanato 리간드의 다리결합을 포함하고 있는 dicobaloximes의 조성에 대한 증거로 말단의 thiocyanocobaloxime (SCNCo$(DH)_2$(L))으로부터 dicobaloxime이 형성되면서 vCN이 $20-45cm^{-1}$ 증가하게 되는 적외선 데이터를 들 수 있다. 이러한 두 일련의 물질에 대한 더많은 특성을 ($^1H$, $^{13}C$) NMR, LCMS 및 원소분석을 통하여 확인하였다. Thiocyanato (L) cobaloximes 및 thiocyanato로 연결된 dicobaloxime의 항균 활성은 E. Coli에 의해 조사하였다. 두 단량체와 이합체 모두의 DNA-결합 행동은 분광학적 방법 및 점성도 측정을 통하여 조사하였다. 그 결과 이합체 착물은 calf-thymus DNA와 DNA의 염기쌍에 말단의 벤질 고리를 통해 사이에 끼인 형태로 결합되어 있음을 나타내었다. 단량체 착물은 DNA와 상호작용하지 않는 것으로 관찰되었다. Complexes of thiocyanato(L)cobaloximes where L is urea, acetamide, semicrabazide and formamide were synthesized and characterized. The reaction of thiocyanato (L) cobaloximes (SCNCo$(DH)_2$(L)) with benzyl (aquo) cobaloxime $PhCH_2Co(DH)_2(OH_2)$ was found to produce a series of thiocyanato bridged dicobaloximes of a general formula of $PhCH_2Co(DH)_2SCNCo(DH_2)(L)$. Evidence for formulation as dicobaloximes containing thiocyanato ligand bridges was obtained from infrared data which show $20-45cm^{-1}$ increase in vCN upon formation of the dicobaloxime from the corresponding terminal thiocyanocobaloxime (SCNCo$(DH)_2$(L)). Further characterization of these two series was done on the basis of ($^1H$,$^{13}C$)NMR, LCMS and elemental analysis. Anti-microbial activity of thiocyanato(L)cobaloximes and thiocyanato bridged dicobaloximes were screened against E. Coli. The DNA-binding behaviors of both monomers and dimers were investigated by spectroscopic methods and viscosity measurements. The results indicated that the dimer complexes bind with calf-thymus DNA in an intercalative mode via the terminal benzyl ring into the base pairs of DNA. It was observed that the monomer complexes did not interact with DNA. Fluorescence spectra for the interaction between thiocyanato bridged dicobaloximes and DNA were also studied.
A.B.Joshi,D.Satyanarayana,K.S.Chandrashekar,E.V.S.Subrahmanyam 한국생약학회 2004 Natural Product Sciences Vol.10 No.3
From the flowers of Ervatamia coronaria four indole alkaloids have been isolated and characterized as harmine, heyneanine, voacristine and apparicine with the help of various spectral data. The alkaloids Harmine and Heyneanine are reported first time from the flowers of Ervatamia coronaria.