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홍금원,임재수,서희철,임해창 고려대학교 컴퓨터과학기술연구소 2001 JOURNAL OF COMPUTER SCIENCE & ENGINEERING TECHNOLO Vol.3 No.-
본 논문에서는 한국어의 특성을 고려한 용례 검색 시스템을 제안한다. 제안된 시스템은 직접 용례 검색과 색인 기반 용례 검색을 제공한다. 직접 용례 검색에서는 원시 말뭉치에서 한글 음절 단위의 검색뿐만 아니라 한글 자소 단위의 검색이 가능하며, 색인 기반 용례 검색에서는 어절, 형태소, 그리고 체계화된 품사정보를 이용한 검색이 가능하다. 검색속도 및 색인된 파일의 크기는 실험을 통하여 최적화 한다. 사용자는 검색된 용례로부터 연산 및 정렬 과정을 거쳐서 보다 정확하게 선별된 용례를 얻을 수 있다. 본 시스템을 통해 얻어진 용례 정보는 사전 편찬 등의 한국어 연구의 기초 자료로 활용할 수 있으며, 말뭉치를 기반으로 한 다양한 분야에서 활용할 수 있을 것이다. In this paper, we propose the concordance system considering the characteristics of Korean. The proposed system provides two kinds of retrieval method: direct access retrieval and index based retrieval. In direct access retrieval method, it is possible to retrieve examples using grapheme-based query as well as syllable based query. In index-based retrieval method, it is possible to retrieve examples using eojeol, morpheme, or part-of-speech. The speed of the system and the size of the indexed file is optimized through several experiments. Users can acquire the exact and selective examples from previously retrieved items by filtering and/or sorting. The linguistic information acquired by the system can be utilized as basic data for Korean Linguistic research such as lexicography and it can be used in various application fields based on corpus.
장태원,김윤규,윤동영,이창희,홍영습,신해림,정갑열,김준연 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4
Objectives : This study was carried out to suggest preventive methods for hypertension in cold-exposed workers. Methods : In 11 refs·iteration industries, 68 workers working in refrigerated areas more than one time per day were selected as the exposed group, and 68 workers not exposed to cold were selected as the control group. We interviewed the subjects with a questionnaire covering occupational history, and conducted clinical and laboratory tests including measurements of blood pressure and core temperature. Results : The systolic blood pressure in the exposed group(130.0±13.3 mmHg) was significantly higher than that recorded In the control group(118.3±12.1 mmHg), as was the diastolic blood pressure in the exposed group(82.7±8.5 mmHg) versus the control group(77.4±8.7 mmHg). The core temperature in the exposed group(36.1±0.7℃) was significantly lower than that experienced in the control group (36.4±0.5℃). In logistic regression analysis, age, cold exposure severity and milk intake were significant variables, with odds ratios of 5.204(95 % CI 1.440∼18.812), 2.674(95 % CI 1.080∼6.618), and 0.364(95 % Cl 0.141∼0.942) , respectively. Conclusions : Our study suggests that cold-exposed workers have higher a higher risk of hypertension, and that their core temperature is lower. Risk factors affecting hyper-tension of cold-exposed workers include age, cold exposure severity and milk intake. For the prevention of hypertension, cold-exposed workers should minimize cold-exposure time as much as possible.
Basic phenotyping platform for genetically engineered mouse at KRIBB
Hae Rim Kim,Eun Kyoung Kim,Yong Sub Byun,Kang Ju Seong,Ju Young Lee,Yu Rim Kim,Min Young Lee,Sang Mi Cho,Taek Chang Lee,Hae Jin Lee,Young Ho Kho,Ok Seong Moon,Young Won Seo,Ki Hoon Lee,Hoyoung Ghang,W 한국실험동물학회 2015 한국실험동물학회 학술발표대회 논문집 Vol.2015 No.8
국내 산란계의 주요 바이러스성 질병에 대한 혈청학적 모니터링 결과 및 분석 (pp.361-372)
이혜림(Hae Rim Lee),김종만(Jong Man Kim),김진형(Jin Hyung Kim),김창문(Chang Moon Kim),소현희(Hyun Hee So),이동우(Dong Woo Lee),하봉도(Bong Do Ha),홍성철(Song Chol Hong),모인필(In Pil Mo) 韓國家禽學會 2010 韓國家禽學會誌 Vol.37 No.4
본 연구에서는 충북대학교 조류질병학실험실에 2009년 한 해동안 의뢰된 산란계의 혈청 검사 결과에 대해 분석하여, 산란계의 주요 질병에 대한 국내 산란계의 면역 상태 및 질병 감염 실태를 파악하였다. 검사 대상 질병은 AI, ND, IB, aMPV, EDS'76, IBD, CIA이었으며, 산란계의 성장 단계에 따라 주령 구간을 나누어 분석하였다. AI, ND, IB는 모체이행항체가 감소한 후 산란 기간에 걸쳐 혈청 역가가 안정적으로 형성되는 특징을 보여 주었다. 그러나 AI는 모든 주령 구간에 걸쳐 음성인 계군이 존재하는 반면, ND는 3~10주령 구간의 한 음성 계군을 제외하고 전 주령에 걸쳐 100%의 계군 양성률을 보이고, ND의 평균 GMT가 AI의 평균 GMT보다 높았는데, 이는 두 질병의 백신 정책의 차이에 기인한 것이다. IB의 산란기의 안정적인 역가는 백신 역가에 산란기 전반에 걸친 야외 감염 개체의 존재로 인한 야외감염 역가가 더해진 것으로 판단된다. aMPV는 2009년에 백신을 실시하지 않았던 질병이므로, 양성 역가를 통해 aMPV의 야외 감염을 추적할 수 있었으며, GMT 변화 및 계군 내양성 개체율의 증가 경향을 통해 일령이 증가할수록 야외감염률이 증가하는 양상을 파악할 수 있었다. EDS'76은 산란 기간에 걸쳐 높은 양성률과 낮은 변이계수를 보여 야외감염이 아닌 백신에 의한 역가 형성이 대부분임을 알 수 있었다. IBD의 모체이행항체는 높은 수준으로 이행되는 것을 확인하였으며, CIA는 백신을 적용하지 않은 계군에서 양성과 음성 계군이 모두 존재하였으며, 그 차이는 차단 방역에 기인하는 것으로 판단되었다. 본 연구를 통하여 국내 산란계에서의 혈청 역가 분포를 파악하는데 많은 정보를 얻을 수 있었으나, 향후 지속적인 야외 계군의 혈청학적 모니터링이 되어야 할 것으로 판단된다. Serological evaluation for the poultry is important for various reasons, such as designing and assessing the vaccination program and diagnosing diseases and for this reason, serologic tests for the layer flocks have been conducted on a regular basis. Moreover, the nationwide serological survey and analysis are essential to understand the epidemiological status of national poultry industry. In this sense, the study was conducted to evaluate the immune status of the layer flocks with the sera submitted to Avian Disease Laboratory, Chungbuk National University in 2009, and several important viral diseases were selected for evaluation including low pathogenic avian influenza (LPAI), Newcastle disease (ND), infectious bronchitis (IB) and avian metapneumovirus (aMPV). For LPAI and ND, the age-related patterns of geometric mean titer (GMT) changes were similar but there were differences in the flock positive rate and the level of GMT due to the different vaccination policy. In the case of IB, the values of GMT showed that the field infection was more prevalent than expected. For aMPV, positive birds in a flock increased as the layers got older, which reflected the course of field infection because vaccination against aMPV was not allowed in 2009. From this study, the immune status for the main viral diseases in layers became more clarified but this information was limited because of only one year study. Therefore, serological survey needs to be conducted on a yearly basis and furthermore include broilers and breeders for a better understanding of the health status in the national poultry industry.
임창수,최해룡,정용구,박윤관,정흥섭,이훈갑,이기찬,주정화 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6
Patterns of brain-stem compression and secondary brain-stem evoked postentials were investigated to correlate with expanding mass volume and location in mass-induced supratentorial brain compression in cats in which the subjects were divided into four experimental group i.e., frontal, temporal, parietal, and occipital brain-compressed groups. Postmortem inspection of the brain-stem showed either unilateral or bilateral dorsal herniation of the brain in frontal and temporal brain-compressed groups and dorsolateral herniation in parietal and occipital brain-compressed groups, respectively. Microscopic examination revealed that the secondary brain-stem hemorrhages were mostly caused by venous bleeding secondary to venous congestion, the bleeding being more severe in occipital brain-compressed group. As the intracranial pressure was raised by expansion of a supratentorial balloon, the late components of the BSEP were suppressed first, followed by the suppression of the early components. In BSEP recording. a significant change was observed in Vth wave with prolongation of latency and decrease in amplitude. This finding suggests that the midbrain is the most vulnerable to compression ischemia. In parietal group, the Vth wave started to be prolonged at 0.4㎖ of balloon expansion and totally disappeared at 1.8㎖ of expansion.
( Chang Il Kwon ),( Pil Won Park ),( Hae Youn Kang ),( Gwang Il Kim ),( Sung Tae Cha ),( Kyung Soo Kim ),( Kwang Hyun Ko ),( Sung Pyo Hong ),( Seong Gyu Hwang ),( Kyu Sung Rim ) 대한내과학회 2007 The Korean Journal of Internal Medicine Vol.22 No.1
Background: Since the pathologic findings of Crohn`s disease (CD) and intestinal tuberculosis (IT) overlap to a large degree, the development of other biomarkers will be of great help for making the differential diagnosis of these 2 diseases. The aim of the present study is to examine the clinical efficacy of using the tissue angiotensin converting enzyme (ACE) assay in making the differential diagnosis between CD and IT. Methods: Tissue specimens were obtained from 36 patients who were diagnosed with CD or IT by the colonoscopic biopsy, as well as by the clinical findings. The expression of tissue ACE was detected by immunohistochemical staining. The optimal cut-off value of the immunoreactive scoring (IRS) system we used to differentiate CD from IT was determined by analysis of the ROC curve and AUROC. Results: Granuloma was present in 15 of 19 patients with CD (78.9%) and in 15 of 17 patients with IT (88.2%). ACE was present in the cytoplasm of the epithelioid cells in the granulomas from 13 of 15 patients with CD and in 14 of 15 patients with IT. The IRS scores of ACE were greater in the patients with CD than that of the patients with IT (8.07±4.38 vs. 4.13±2.47, respectively, p=0.006). In differentiating CD from IT, the AUROC curve for the IRS of ACE was 0.767 with a sensitivity of 66.7%, a specificity of 93.3% and the cut-off point was 7.5. Conclusions: The results of our study suggest that the assessment of the tissue ACE expression can be helpful for making the differential diagnosis between CD and IT.