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Appearance-based Robot Visual Servo via a Wavelet Neural Network
Qingjie Zhao,Zengqi Sun,Fuchun Sun,Jihong Zhu 대한전기학회 2008 International Journal of Control, Automation, and Vol.6 No.4
This paper proposes a robot visual servo approach based on image appearance and a wavelet function neural network. The inputs of the wavelet neural network are changes of image features or the elements of image appearance vector, and the outputs are changes of robot joint angles. Image appearance vector is calculated by using eigen subspace transform algorithm. The proposed approach does not need a priori knowledge of the robot kinematics, hand-eye geometry and camera models. The experiment results on a real robot system show that the proposed method is practical and simple.
Exosomes derived from miR-214-3p overexpressing mesenchymal stem cells promote myocardial repair
Wenwu Zhu,Qingjie Wang,Jian Zhang,Ling Sun,Xiu Hong,Wei Du,Rui Duan,Jianguang Jiang,Yuan Ji,Haoran Wang,Bing Han 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Aims Exosomes are known as nanovesicles that are naturally secreted, playing an essential role in stem-mediated cardioprotection. This study mainly focused on investigating if exosomes derived from miR-214 overexpressing mesenchymal stem cells (MSCs) show more valid cardioprotective ability in a rat model of acute myocardial infarction (AMI) and its potential mechanisms. Methods Exosomes were isolated from control MSCs (Ctrl-Exo) and miR-214 overexpressing MSCs (miR-214OE-Exo) and then they were delivered to cardiomyocytes and endothelial cells in vitro under hypoxia and serum deprivation (H/SD) condition or in vivo in an acutely infarcted Sprague-Dawley rat heart. Regulated genes and signal pathways by miR-214OE-Exo treatment were explored using western blot analysis and luciferase assay. Results in vitro , miR-214OE-Exo enhanced migration, tube-like formation in endothelial cells. In addition, miR-214OE-Exo ameliorated the survival of cardiomyocytes under H/SD. In the rat AMI model, compared to Ctrl-Exo, miR-214OE-Exo reduced myocardial apoptosis, and therefore reduced infarct size and improved cardiac function. Besides, miR-214OE-Exo accelerated angiogenesis in peri-infarct region. Mechanistically, we identified that exosomal miR-214-3p promoted cardiac repair via targeting PTEN and activating p-AKT signal pathway. Conclusion Exosomes derived from miR-214 overexpressing MSCs have greatly strengthened the therapeutic efficacy for treatment of AMI by promoting cardiomyocyte survival and endothelial cell function.
Dynamic simulation based fault detection and diagnosis for distillation column
Wende Tian,Qingjie Guo,Suli Sun 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.1
The model-based fault diagnosis approach is characterized by a powerful process supervision capability with a priori knowledge about the system under consideration. Nevertheless, system complexity, high dimensionality,process nonlinearity and/or lack of good data often hamper its application in chemical engineering systems. A nonsteady state model based fault detection and diagnosis method for the distillation process was developed, using dynamic simulation to monitor the distillation process and identify abnormal sources when large deviations among measuring variables occur. It continuously updates the inner distillation parameters via on-line correction and predicts the trend of measuring variables and determines the existence of malfunctions simultaneously. The distillation model is dependent on transfer equilibrium, mass and heat balance, and is simulated by Euler and two-tier approach. This method was demonstrated with simulated data of a stripping tower collected from the Tennessee Eastman chemical plant simulator.