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Ran Chu,Penglin Liu,Jingying Chen,Xiaodong Cheng,Kezhen Li,Yanci Che,Jianliu Wang,Li Li,Xi Zhang,Shu Yao,Li Song,Ying Zhao,Changzhen Huang,Ying Xue,Xiyu Pan,Junting Li,Zhongshao Chen,Jie Jiang,Beihua 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.2
Objective: To evaluate the impact of bleomycin/etoposide/cisplatin (BEP) and paclitaxel/carboplatin (PC) chemotherapy regimens on the fertility and prognostic outcomes in malignant ovarian germ cell tumor (MOGCT) patients who underwent fertility-sparing surgery (FSS). Methods: A propensity score matching algorithm was performed between the BEP and PC groups. The χ2 test and the Kaplan-Meier method were used to compare the fertility outcome, disease-free survival (DFS) and overall survival (OS). The Cox proportional hazards regression analysis was used to identify risk factor of DFS. Results: We included 213 patients, 185 (86.9%) underwent BEP chemotherapy, and 28 (13.1%) underwent PC chemotherapy. The median age was 22 years (range, 8–44 years), and the median follow-up period was 63 months (range, 2–191 months). Fifty-one (29.3%) patients had a pregnancy plan, and 35 (85.4%) delivered successfully. In the before and after propensity score matching cohorts, there were no significant differences in spontaneous abortion, selective termination of pregnancy, during-pregnancy status, and live birth between the BEP and PC groups (p>0.05). Fourteen (6.6%) patients experienced recurrence, including 11 (5.9%) in the BEP group and 3 (10.7%) in the PC group. Four (1.9%) patients in the BEP group died. Kaplan-Meier analysis revealed no significant differences in DFS (p=0.328) and OS (p=0.446) between the BEP and PC groups, and the same survival results were observed in the after matching cohort. Conclusion: The PC regimen is as safe as the BEP regimen for MOGCT patients with fertility preservation treatment, and no differences were observed in fertility and clinical prognosis.
Research on Grey Predictive Control of PMSM Based on Reduced-order Luenberger Observer
Huang Xianghui,Guan Penglin,Pan Hongguang,Liu Shulin,Du Guanghui,Huang Xinyi,Wang Xueyan 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.5
To further improve the dynamic and anti-interference performance of permanent magnet synchronous motor (PMSM) control system, a dual closed loop model predictive control (MPC) strategy combining with grey prediction and reduced-order Luenberger observer is proposed in this paper for speed and current control. To be specifi c, fi rstly, the dual closed loop MPC strategy is introduced based on the mathematical model of PMSM, that is, the model predictive controller is used for the outer loop of speed, and the deadbeat predictive controller for the inner loop of current. Secondly, considering the grey prediction method can establish grey model and whiten the system grey quantity to some extent, it is used in the PMSM control system to improve the dynamic performance. Finally, to solve the problem that the motor is easy to be aff ected by disturbances, a reduced-order Luenberger observer is designed to combine with the model predictive controller to improve the system anti-interference performance. The simulation results show that the dual MPC strategy based on grey prediction makes the system more stable and dynamic response faster, while the dual MPC strategy combining with the grey prediction and the reduced-order Luenberger observer makes the system more resistant to load disturbance.