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유현아,김은영,서민지,정은,조민정,오현진,장지혜,박지찬,이정의,박석영 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2
Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.
항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향
소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3
Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.
오윤경,장진영,박상학,류소연 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Pmpose: To investigate the characteristics of Myers-Briggs Type Indicator (MBTI) in premedical students of one medical college and to compare the personality profiles of them with those of other studies which involved the K-orean university students and other country population. Mateiials and Methods: The MBTI was used to measure the personality profiles of premedical students at the Center for Teaching & Leaming of Chosun University. One hundred and twenty five premedical students participated in this study and the MBTI profiles of them were compared to those of K-orean university students (1,441 persons), i.e. their potential patients and those of the United Kingdom (UK.) Population (1,634 persons) and a sample of UK- doctors (313 persons) of one medical college involved in other studies. Results: The premedical students had a preference for Introversion (62%) rather than Extraversion (38%), Sensing (70%) rather than Intuition (30%), Thinking (66%) rather than Feeling (34%), and Judging (57%) rather than Perceiving (43%). There were more Thinking (66% vs 57%, p=0.071) in the premedical students than in K-orean university students with borderline significance. There were significantly more Thinking (66% vs 46%, P=0.000) and more Introversion (62% vs 48%, p=0.002) than in UK- adult population. Also there were significantly more Sensing (62% vs 48%, p=0.002), significantly less Judging (57% vs 68%, P=0.034), and more Introversion (62% vs 53%, 0=0.094) with borderline significance than in UK doctors. But no difference was shown in Thinking between the premedical students and UK- doctors, Conclusion: The personality profiles of the premedical students in this study differed in Thinking with borderline significance from K-orean university students and significantly differed from the UK adult population in Thinking and Introversion showing the cultural difference. No difference of Thinking between the premedical students and UK doctors despite of cultural difference suggests the correlation between the Thinking and medical professional choice.
진행된 자궁경부암에서 단순분할조사법(Simple Fractionation)과 다수회 분할 조사법(Hyperfractionation)의 비교 : 종양의 조절과 합병증
오지영,이태화,김성한 고신대학교 의과대학 2011 고신대학교 의과대학 학술지 Vol.26 No.1
OBJECTIVES: To discern in advanced uterine cervical cancer whether the hyperfractionation is more effective in tumor control and in reducing radiation complication rates than the simple fractionation. METHODS: We retrospectively reviewed the medical records of 184 patients with advanced cervical cancer at our hospitals from January 2000 to December 2004. All patients were treated with radiation, 114 patients with simple fractionation, and 70 patients with hyperfractionation. RESULTS: Mean age was 55.4 years at baseline study. Complications were occurred in 90 patients of the 184 patients who treated with radiation therapy. Of these, 48 patients suffered from gastrointestinal complications, 24 patients suffered from genitourinary complications and 18 patients had both complications. Complications were occurred in 72 cases in simple fractionation group and 40 cases in hyperfractionation group. 77 patients had acute complications and 13 patients had chronic complications. There was no statistically significant difference between two groups (P = 0.772). Mild complication were occurred in 75 patients and severe complication were occurred in 15 patients, there was no statistically significant difference in two groups (P = 0.495). 66 patients had gastrointestinal complications and 42 patients had genitourinary complications, there was no statistical significance in two groups (P = 0.910). CONCLUSION: Many complications were occurred in patients who treated with radiation therapy, but there was no statistically significant survival and complication difference in two groups. Further research is needed.
외상성 뇌손상 환자의 지능 장애와 K-WAIS 소검사내 분산도
오상우,김지영,노승호 圓光大學校 醫科大學 神經精神科學敎室 1997 圓光精神醫學 Vol.13 No.2
본 연구는 외상성 뇌손상 환자의 병전 지능을 추정하여, 추정된 지능을 현재 지능과 비교하고, K-WAIS 소검사내 분산도 분석을 시행하여 인지 기능의 효율성을 평가하고자 하였다. 연구 결과, 외상성 뇌손상 환자 집단은 정신분열증 집단이나 기타 임상 집단의 환자들에 비해 지능이 유의하게 저하되어 있었다. 그러나 소검사내 분산도 분석에서는 외상성 뇌손상 환자 집단이 다른 두 집단보다 인지적 효율성이 더 높았다. In this study, premorbid IQ in patients with traumatic brain injury were estimated and compared with measured IQ, and examined efficiency of cognitive function through K-WAIS intrasubtest scatter analysis. These results suggested that traumatic brain injury patient's IQ were significantly lower than those of the schizophrenia and other psychiatric patients. But traumatic brain injury patient's cognitive efficiency were higher than those of the schizophrenia and other psychiatric patients.
색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석
송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2
Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)
오윤경,장지영,도남용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Pmpose: To present the characteristics and treatment outcome of laryngeal cancer patients who were treated by radiation therapy with or without surgery and chemotherapy. Materials and Melhods: A total of 23 patients with laryngeal cancer treated from 1998 through 2003 were available for analysis. The primary site of the cancer was the glottis in 12 patients, the supraglottis in 10 patients, and the subglottis in 1 patient. The stages were Ⅰ in 7 patients (30%), Ⅱ in 5(22%), Ⅲ in 3(13%), IV in 6(26%), and recurrent in 2(9%). The minimum follow-up period in surviving patients is 3 years after the radiation therapy. They were treated by radiation therapy at least 44 Gy with or without surgery and chemotherapy. Results: The overall survival at 1, 2, 3, 5 years in total patients were 95.6%, 82.6%, 78.2%, 73.9%. The overall survival at 1, 2, 3, 5 years in the glottic cancer patients were 100%, 100%, 91.6%, 91.6%. The overall survival at 1, 2, 3, 5 years in the supraglottic cancer patients were 90%, 70%, 70%, 60%. The 3-year overall survival showed the significant difference according to the primary site (glottic vs. supraglottic), cervical lymph node status (negative vs. positive), and overall time of radiation therapy (<50 days vs. 50-59 days vs. ≥60 days), Conclusion: The overall survival rate of laryngeal cancer patients in this analysis seems to be similar in early glottic cancers and relatively good in supraglottic cancers as compared with the results of other studies even though the total number of patients is small.