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김계형,김낙현,김문석,김충종,전재현,박완범,장원종,박상원,김익상,오명돈,최강원 대한감염학회 2008 감염과 화학요법 Vol.40 No.6
Infectious diseases imported from other countries have increased as more and more Koreans are going abroad for various purposes. Tsutsugamushi disease from other endemic area such as Southeast Asia is important, because it can occur in any season and eschar may be absent. We report a case of imported tsutsugamushi disease acquired in the Philippines. A patient presented with fever, headache, and maculopapular skin rash. However, eschar was absent. Polymerase chain reaction (PCR) for 56-kDa gene of Orientia tsutsugamushi using buffy coat was positive. Serum indirect immunofluorescent antibody assay was initially negative but became positive with a titer of 1:320 at follow-up, Sequencing analysis revealed the strain to be 100% identical to the TW73R strain identified in Taiwan. After the patient received doxycycline, body temperature normalized in 12 hours. Tsutsugamushi disease is one of the differential diagnoses that should be included for patients with fever who have recently returned from Southeast Asian countries. PCR for O. tsutsugamushi using patient's buffy coat was useful for early diagnosis.
발전기 보호제어를 위한 Bay Controller 설계에 관한 연구
張樂元(Nak-Won Jang),禹天熙(Chun-Hee Woo),李聖煥(Sung-Hwan Lee) 대한전기학회 2008 전기학회논문지 P Vol.57 No.1
In this paper, we designed the bay control unit that is based on the microprocessors and integrates with the new technology of electrical, electronic, and mechanical fields. Nowadays the customers have required much more integrated multi-protection relay, monitoring, control devices and power management for better and easier maintenance, performance, electrical system analysis and communication according to new trend of switchboard. This bay controller supplies those requirements of customers with easy handling and operation. This bay controller provides a graphic display with rear-lit liquid crystal LCD and push buttons as kinds of HMI(Human Machine Interface). This bay controller provides the parameter setting program, control setting program, various editors and fault recording and analysis program on Windows/95/98/NT/2000/XP for HMI. In addition, this bay controller can be set manually and this manual setting function helps user to interface easily.
급성 신우신염 치료시 아미노글라이코사이드(Micronimicin Sulfate)에 의한 유사 Bartter씨 증후군의 발생에 관한 평가
장우영,김진영,최낙원,한상웅,김호중,박석규,문중돈,나경선,윤경택,위형중,최창렬,조형도,안유현 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.5
The aminoglycoside antibiotics is widely used in the treatment of infectious caused by gram-negative bacteria and for synergistic effect with(β-lactam antibiotics. However, its therapeutic usefulness is limited by this potential nephrotoxicity and by disturbance of electrolyte homeostasis resulting in hypomagnesemia, hypokalemia, hypocalcemia such as Bartter-like syndrome. Many case repots have been reported on development of Bartter-like syndrome after aminoglycosides administration. But these reports had the many differences of such as types of aminoglycosides, age of patients, duration and total dose of treatment, combined antibiotics and baseline diseases. Therefore, the purpose of this study is to assess the effects of micronomocin sulfate on magnesium, calcium and potassium status of patients in acute pyelonephritis. Twenty one patients in acute pyelonephritis(18 female/3 male, ages 20-75) was treated with single or combined antibiotics. Eleven of twenty one patients as study group were treated with boh micronomicin sulfate(aminoglycoside, 4mg/kg/day, during 5-8days) and flomoxef sodium (3rd cephalosporine, 2g/day, during 5-8days), and ten of twenty one patients as control group were treated only with flomoxef sodium(3rd cephalosporine. 2g/day. during 5-8days). Renal values, plasma and urinary electrolytes were measured before and at the end of IV antibiotic therapy. After micronomicin sulfate administrated for 6.4±1.5days, serum Mg, Ca, K, FEMG (fractional excretion of Mg), TTKG(transtubular K concentration gradient) and FEca.(fractional excretion of Ca) did not significantly change(p$gt;0.05). Therefore, those results suggest that micromonicin sulfate therapy within dose of 24mg/day(4mg/kg/day) for 6.4±1.5days may not cause disturbance of electrolyte homeostasis such as Bartter-like syndrome in acute pyelonephritis. Howerever, electrolyte disturbance is an important complication when aminoglycosides is given in larges doses over extended periods. Therefore, monitoring of blood concentration and urinary loes of electrolyte should be carried out along with careful observation of Bartter-like syndrome.
PLD 법으로 제작된 PLZT 박막의 산소압에 따른 구조 및 전기적 특성
장낙원,Jang, Nak-Won 한국마린엔지니어링학회 2006 한국마린엔지니어링학회지 Vol.30 No.8
The structural and electrical characteristics of PLZT thin films fabricated onto $Pt/IrO_2/Ir/Ti/SiO_2/Si$ substrates by a pulsed laser deposition were investigated to develop the high dielectric thin films for capacitor layer of semiconductor memory devices The slim region 14/50/50 PLZT thin films were fabricated by PLD and estimated the characteristics for memory application 14/50/50 PLZT thin films have crystallize into perovskite structure at the $600^{\circ}C$ deposition temperature, 200 mTorr of oxygen pressure, and 2 $J/cm^2$ of laser energy density. In this condition PLZT thin films had the dielectric constant as high as 985, storage charge density 8.17 ${\mu}C/cm^2$ and charging time 0.20 ns. Leakage current density was less than $10^{-10}A/cm^2$ up to 5 V bias voltage.
전자코와 푸리에 변환 근적외선 분광기를 사용한 사골 추출물의 향기 성분 변화 분석
장낙훈(Nak-Hoon Jang),조연수(Yon Soo Cho),박수원(Su Won Park),동혜민(Hyemin Dong),한현정(Hyun Jung Han),노봉수(Bong-Soo Noh) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.6
이 연구는 이전에는 없던 4단계 열수 추출 공정이 사골 내 특유 이취를 효과적으로 제거하고 풍미 성분을 생성시킬 수 있는지 MS-전자코와 FT-NIR을 사용하여 분석하였다. 그 결과, 4단계 열수 추출 공정은 상대적으로 풍미 성분이 많이 생성되었고, 완제품의 경우 진공 농축 공정을 추가적으로 처리함으로써 추출액에 남아있는 지방 유래 휘발성 이취가 감소된 것을 볼 수 있었다. 또한 이렇게 약해진 이취는 생성된 풍미에 masking 되는 효과가 더해져, 다른 회사의 제품과 차별성이 있다고 할 수 있다. This study was conducted to investigate whether four hot-water extraction steps could effectively remove offflavor from bovine bone extracts and produce compounds with pleasant aroma. Experiments were performed using a mass spectrometry-electronic nose and Fourier transform-near infrared spectrometer (FT-NIR). Off-flavor compounds were removed by washing and extraction with hot water. Steaming treatment produced compounds with a better aroma, such as 4-methylthiazole. In addition, a change in flavor compounds was observed in treated samples.