Current Status of the Estimation on the Number of People Who Living with HIV and the Rate of Undiagnosed Cases

Myeongsu Yoo,Cheol-Hee Yoon,Byeong-Sun Choi 대한미생물학회 2020 Journal of Bacteriology and Virology Vol.50 No.3

Status of HPV vaccination among HPV-infected women aged 20–60 years with abnormal cervical cytology in South Korea: a multicenter, retrospective study

성재현,류상미,Myeongsu Yoo,이정규,김기순,지영미,조치흠,김석모,홍성란,정대훈,이원철,박종섭,김태진,Mee Kyung Kee 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.1

Objectives: Since 2007, human papillomavirus (HPV) vaccines have been administered for the prevention of cervical cancer in Korea. We investigated the status of HPV vaccination among HPV-infected adult women with abnormal cervical cytology before the introduction of National Immunization Program. Methods: From 2010 to 2016, HPV-positive women (age, 20–60 years) with atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion (LSIL) were enrolled from five hospitals across Korea. Their HPV genotype, epidemiologic, and clinical data, including HPV vaccination history, were obtained. We compared the epidemiological characteristics and prevalence of HPV-16/18 genotypes between vaccinated and unvaccinated women. Results: Among the 1,300 women, approximately 26% had a history of vaccination. Vaccinated patients were significantly younger, unmarried, and had a higher education level than unvaccinated women. For HPV-vaccinated individuals by vaccine dose, there was a significant younger age at vaccination initiation (p=0.025), longer duration from HPV vaccination to Pap test date (p=0.001), and lower proportion of HPV-16/18 (p=0.028) in the women with three doses. There was a significantly lower prevalence of HPV-16/18 genotypes in women who were vaccinated at least 12 months prior than in unvaccinated women (adjusted prevalence ratio [aPR]=0.51; 95% confidence interval [CI]=0.29–0.88). For women with LSIL, the prevalence of the HPV-16/18 genotypes was significantly lower in women who were vaccinated more than 12 months prior than in unvaccinated women (aPR=0.35; 95% CI=0.13–0.96). Conclusion: This study highlighted the status of HPV vaccination and the prevalence of HPV-16/18 genotypes among HPV-infected women with abnormal cervical cytology according to HPV vaccination. It provides preliminary information regarding the status of HPV vaccination among Korean adult women.

HCGIR(중량 천장유리 설치로봇)의 하드웨어 설계

이승열(SeungYeol Lee),유석종(SeokJong Yoo),최종호(JongHo Choe),길명수(MyeongSu Gil),이계영(KyeYoung Lee),이상헌(SangHeon Lee),한창수(ChangSoo Han) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11

The objective of the study is to propose a heavy ceiling glass installation robot in hazardous construction site. This system combines a basic system composed of a multi-DOF manipulator and an aerial lifts with an additional module for construction works. According to an additional module type combined with a basic system, it can be used in a various construction fields. In this study, we describe a construction robot which helps a human operator handle easily heavy ceiling glass in case of using the cooperation system on construction site. This study introduces a HRI (Human Robot Interface) as additional module for a HRC (Human-Robot Cooperation) in construction site.

Effect of socioeconomic disparities on the risk of COVID-19 in eight metropolitan cities, the Korea: a community-based study

Hwang Myung-Jae,Park Shin Young,윤태호,Jang Jinhwa,Lee Seon-young,Yoo Myeongsu,Kim Yoo-Yeon,정해관,Kwon Donghyok,김종헌 한국역학회 2022 Epidemiology and Health Vol.44 No.-

OBJECTIVES: Socioeconomic disparities have been reported as the main risk factors contributing to the spread of coronavirus disease 2019 (COVID-19) at the community level. We conducted an epidemiological study on the risk of COVID-19 incidence using area deprivation indices (DIs) depending on the characteristics of the susceptible population. METHODS: The database of the confirmed COVID-19 cases in eight metropolitan cities, the Republic of Korea, from January 20, 2020 to December 31, 2021, was combined with the area DIs and standardized prevalence of diabetes and hypertension from the community health survey. The relative risk (RR) was estimated using a generalized linear model with Poisson distribution by age group. RESULTS: The risk of COVID-19 incidence increased with the increasing age group, especially in patients aged ≥ 75 years. The RR per interquartile range increment of total social deprivation index (total SDI) was 1.54 (95% confidence interval [CI]: 1.34- 1.70) in the COVID-19 incidence. Especially, the risk of COVID-19 incidence in the first wave was about three times higher in the region belonging to the lowest socioeconomic status than in the region with the highest socioeconomic status. The risk was 3.08 (95% CI: 2.42 to 3.78) based on the total SDI and 3.13 (95% CI: 2.53 to 3.83) based on the social deprivation index. CONCLUSIONS: This study provides scientific evidence that socioeconomic inequity is an important risk factor for the spread of COVID-19. This finding suggests that a mid-to-long-term strategy is needed for the susceptible population to reduce the burden of COVID-19 in the community. KEY WORDS: COVID-19, Socioeconomic disparity, Area deprivation index, Community, Korea

Prospective cohort data quality assurance and quality control strategy and method: Korea HIV/AIDS Cohort Study

Soo Min Kim,Yunsu Choi,Bo Youl Choi,Minjeong Kim,Sang Il Kim,Jun Young Choi,Shin-Woo Kim,Joon Young Song,Youn Jeong Kim,Mee-Kyung Kee,Myeongsu Yoo,Jeong Gyu Lee,Bo Young Park 한국역학회 2020 Epidemiology and Health Vol.42 No.-

OBJECTIVES: The aim of effective data quality control and management is to minimize the impact of errors on study results by identifying and correcting them. This study presents the results of a data quality control system for the Korea HIV/AIDS Cohort Study that took into account the characteristics of the data. METHODS: The HIV/AIDS Cohort Study in Korea conducts repeated measurements every 6 months using an electronic survey administered to voluntarily consenting participants and collects data from 21 hospitals. In total, 5,795 sets of data from 1,442 participants were collected from the first investigation in 2006 to 2016. The data refining results of 2015 and 2019 were converted into the data refining rate and compared. RESULTS: The quality control system involved 3 steps at different points in the process, and each step contributed to data quality management and results. By improving data quality control in the pre-phase and the data collection phase, the estimated error value in 2019 was 1,803, reflecting a 53.9% reduction from 2015. Due to improvements in the stage after data collection, the data refining rate was 92.7% in 2019, a 24.21%p increase from 2015. CONCLUSIONS: Despite this quality management strategy, errors may still exist at each stage. Logically possible errors for the post-review refining of downloaded data should be actively identified with appropriate consideration of the purpose and epidemiological characteristics of the study data. To improve data quality and reliability, data management strategies should be systematically implemented.

Epidemiological characteristics of HIV infected Korean: Korea HIV/AIDS Cohort Study

최윤수,최보율,Soo Min Kim,Sang-Il Kim,June Kim,Jun Young Choi,Shin Woo Kim,Joon Young Song,Youn Jeong Kim,Dae Won Park,Hyo Youl Kim,최희정,Mee-Kyung Kee,YoungHyun Shin,Myeongsu Yoo 한국역학회 2019 Epidemiology and Health Vol.41 No.-

OBJECTIVES: To manage evidence-based diseases, it is important to identify the characteristics of patients in each country. METHODS: The Korea HIV/AIDS Cohort Study seeks to identify the epidemiological characteristics of 1,442 Korean individuals with human immunodeficiency virus (HIV) infection (12% of Korean individuals with HIV infection in 2017) who visited 21 university hospitals nationwide. The descriptive statistics were presented using the Korea HIV/AIDS cohort data (2006-2016). RESULTS: Men accounted for 93.3% of the total number of respondents, and approximately 55.8% of respondents reported having an acute infection symptom. According to the transmission route, infection caused by sexual contact accounted for 94.4%, of which 60.4% were caused by sexual contact with the same sex or both males and females. Participants repeatedly answered the survey to decrease depression and anxiety scores. Of the total participants, 89.1% received antiretroviral therapy (ART). In the initial ART, 95.3% of patients were treated based on the recommendation. The median CD4 T-cell count at the time of diagnosis was 229.5 and improved to 331 after the initial ART. Of the patients, 16.6% and 9.4% had tuberculosis and syphilis, respectively, and 26.7% had pneumocystis pneumonia. In the medical history, sexually transmitted infectious diseases showed the highest prevalence, followed by endocrine diseases. The main reasons for termination were loss to follow-up (29.9%) and withdrawal of consent (18.7%). CONCLUSIONS: Early diagnosis and ART should be performed at an appropriate time to prevent the development of new infection.