렙토스피라증의 진단에 있어 수동혈구응집반응법과 육안응집반응법의 정확도에 관한 연구

최보율,김영규,이수진,송재철,박항배 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.2

Before 1984, Leptospirosis had been reported sporadically in middle inland of Korea as hemorrhagic pneumonia like disease, epidemic pulmonary hemorrhagic fever or epidemic pneumonitis since 1975. The epidemiologic characteristics of this disease were found out and the agent was isolated microbiologically after a large epidemic in 1984. Thereafter many consecutive studies for leptospirosis had been performed in the realm of epidemiology, microbiology and clinical field. But in order to appropriate control of Leptospirosis there are many problems such as organizing surveillance system for early diagnosis and treatment, identifying sero-group and serovar in each epidemic area and assessing vaccine efficacy. The objectives of this study was to find out easily applicable diagnostic methods to be used in a rural community surveillance system. Two diagnostic methods, passive hemagglutination(PHA) test and macroscopic agglutination test(maAT) were measured against their accuracies, sensitivity, specificity and predictive value of positive and negative. 301 sample sera from 270 human cases was collected through Leptospirossis surveillance system in a rural community during 1989-1992. Microscopic agglutination test(MAT) were used for confirmed diagnosis according to WHO guideline with 4 strains; Icterohemorrhagiae lai and Canicola canicola Hond Utrecht IV as standard strians and 6P-014-1 and YP-35-1 as strains isolated in Korea in 1986. The results are as follows. 1. 75(24.9%) among 301 sample sera and 49(18.1%) among 270 persons was serologically positive with MAT. 2. Agreement between PHA and MaAT was very low(k-coefficient≤0.252). 3. In PHA, specificity was very high(≥0.96) but sensitivity was very low(≤0.28). 4. In MaAT, specificity(≥0.73) was relatively lower than PHA but sensitivity (≥0.79) was significantly higher than PHA, especially false-positive rate case was absent in MAT's high antibody titer(above 1:640). It was concluded that MaAT method was a very useful diagnostic tool for early diagnosis of Leptospirosis in a rural community surveillance system, provided that confirmed diagnosis with MAT method be carried out in laboratory of medical school or research institute such as National Institute of Health or Provicial government Institute of Health and Environment.

집단 검진을 통한 조기 위암 발견 관리 체계 개발에 관한연구

최보율,기모란,한동수 한국건강관리협회 1999 건협 Report Vol.2 No.-

Welcome to Epidemiology and Health

Bo Youl Choi 한국역학회 2009 Epidemiology and Health Vol.31 No.-

The Korean Society of Epidemiology publishes a scholarly journal titled 'Korean Journal of Epidemiology', which announces and discusses the results of epidemiological studies from the past 30 yr. Since its first publica-tion in 1979, the journal has contributed to the advancement of epidemiology as well as the prevention and control of disease, and the promotion of health in Korea. In 2009, the editorial board has decided to publish the journal in English to contribute internationally, and change the journal's name. The new name of the journal is 'Epidemiology and Health'. The abstract and full text of articles will be published as an open access online journal, which will be posted onto the homepage (http://www.e-epih.org/) in real time for anyone in the world to access free of charge. Our editorial policy is that 'Epidemiology and Health' is open to every researcher in fields related to epidemiology, regardless of membership, his or her major and nationality. Editorials, lectures, review papers, original articles, epidemic and case investigations, brief communications and letters will be published to generate active discussion through the journal along with the publication of the papers. 'Epidemiology and Health' welcomes articles from various fields of epidemiology, such as 1) infectious diseases epidemiology, 2) chronic diseases epidemiology, 3) nutritional epidemiology, 4) clinical epidemiology, 5) phar-macoepidemiology, 6) genetic or molecular epidemiology, 7) social epidemiology, 8) environmental or occupa-tional epidemiology, 9) epidemiological methods and biostatistics, 10) disease prevention and control, 11) health promotion and, 12) all other fields related to epidemiology.

우리나라 HIV/AIDS와 결핵 관리 정책에 대한 고찰

최보율(Bo Youl ChoI) 한국역학회 2006 Epidemiology and Health Vol.28 No.1

  Since the early 1990s, Korea has made efforts to strengthen its National Communicable Disease Control System. In 2005, the Korea government developed various goals for communicable diseases control as a part of Health Plan 2010. The goals include 40 objectives, for the achievement of which a variety of programs and research subjects have been developed. These efforts will contribute to raising the preparedness for and response to the global threat of emerging and reemerging infectious diseases. The author reviewed the status, management goals and future tasks of HIV/AIDS and tuberculosis in Korea. HIV/AIDS is an emerging infectious disease, and tuberculosis is an endemic disease in Korea. These two diseases are included in the UN Millennium Development Goal 6.   The number of HIV/AIDS cases reported in Korea at the end of December 2005 was 3,829, of which 721 have died. The reported HIV prevalence rate among adults aged in 15-49 years is below 0.1%, and the infection level is categorized as "very low". However, the number of newly infected cases has been rising rapidly. The goal of HIV/AIDS control in Health Plan 2010 is to reduce the increasing rate of HIV/AIDS to 35% in 2010. Compared with the global Millennium Development Goal, which is to halt and reverse the spread of HIV/AIDS by 2015, we should set up long-tenn, high level goals, in addition to a comprehensive national plan for the prevention and control of HIV/AIDS.   Korea first implemented a Nationwide Tuberculosis Control Program in the 1960s. By 2005, the prevalence of radiologically active tuberculosis had fallen to 0.35% which is one-fifteenth of the level of 1965. Nevertheless, the current prevalence of and death rate from tuberculosis continue to be much higher than those of advanced nations. Given this such a level of infection, the goals of tuberculosis control need to be specified, and an enhanced tuberculosis control program needs to be implemented to reduce the incidence of tuberculosis and associated death rates.

새로 등장하는 전염병과 국가간 전염병의 전파

최보율(Bo Youl Choi),이수진(Soo-jin Lee) 한국항공우주의학협회 2001 항공우주의학회지 Vol.11 No.2

감염병의 새로운 등장

최보율(Bo Youl Choi) 한국역학회 2008 Epidemiology and Health Vol.30 No.2

The term and concept of emerging infectious diseases (EID) has been burgeoned out in the early 1990s and EID were expected as the most important public health problems of all of countries and global community as a whole. EID have been confirmed as the most important health and security problems when the global community has been experienced a lot of outbreaks of EID including avian influenza in Hong Kong (1997), Nipah encephalitis in Malaysia and Singapore (1999), and anthrax bioterrorism in U.S.A. (2001), and SARS outbreaks in global community (2003). Pandemic influenza could be a big disaster in global community in the near future in the situation of the occurrence of H5N1 avian influenza and it’s human cases in southeastern Asian countries. This paper described the EIDs in terms of two epidemiologic transition theories, and described the important EID in global community since 1970s and reviewed the remarkable emerging and re-emerging infectious diseases in Korea since 1990. Seven factors contributing to EID and the convergence model for EID were introduced. In conclusion, the preparedness and response plan of public health authority the role of epidemiologist was suggested. Especially the cooperative activities between epidemiologists and other field or sector’s professionals were emphasized to find out the etiology or risk factors of EID and preparedness and response plan.

Prospective cohort data quality assurance and quality control strategy and method: Korea HIV/AIDS Cohort Study

Soo Min Kim,Yunsu Choi,Bo Youl Choi,Minjeong Kim,Sang Il Kim,Jun Young Choi,Shin-Woo Kim,Joon Young Song,Youn Jeong Kim,Mee-Kyung Kee,Myeongsu Yoo,Jeong Gyu Lee,Bo Young Park 한국역학회 2020 Epidemiology and Health Vol.42 No.-

OBJECTIVES: The aim of effective data quality control and management is to minimize the impact of errors on study results by identifying and correcting them. This study presents the results of a data quality control system for the Korea HIV/AIDS Cohort Study that took into account the characteristics of the data. METHODS: The HIV/AIDS Cohort Study in Korea conducts repeated measurements every 6 months using an electronic survey administered to voluntarily consenting participants and collects data from 21 hospitals. In total, 5,795 sets of data from 1,442 participants were collected from the first investigation in 2006 to 2016. The data refining results of 2015 and 2019 were converted into the data refining rate and compared. RESULTS: The quality control system involved 3 steps at different points in the process, and each step contributed to data quality management and results. By improving data quality control in the pre-phase and the data collection phase, the estimated error value in 2019 was 1,803, reflecting a 53.9% reduction from 2015. Due to improvements in the stage after data collection, the data refining rate was 92.7% in 2019, a 24.21%p increase from 2015. CONCLUSIONS: Despite this quality management strategy, errors may still exist at each stage. Logically possible errors for the post-review refining of downloaded data should be actively identified with appropriate consideration of the purpose and epidemiological characteristics of the study data. To improve data quality and reliability, data management strategies should be systematically implemented.

병원의 관리개선을 위한 원가개념의 도입과 원가분석전산시스템의 효과분석 : K대학병원의 원가분석시스템을 중심으로

최황규,이열원,윤덕보,오건영,정수경 한국병원경영학회 1996 병원경영학회지 Vol.1 No.1

Some of the large sized companies have taken parts in a hospital business with a view or justification to improve medical care regadless of the disadvantageous fee-for-service medical insurance reimbursement system controlled by authorities related. This gradually brought about the financial difficulties to university hospitals as well as general hospitals that were less competitive. In this circumstance the hospital administrators are called for preparing and implementing proper financial strategies by analyzing external circumstances and internal abilities of their hospitals. In this aspect, an effective cost-analysis system in the hospital has been needed for years. K-University hospital developed the practical cost-analysis system and applied it to the hospital management. The effects of const analysis system are as belows : first, the trend of the monthly revenue per medical specialist from March to July in 1996 showed increasing pattern which is different from that in past years. second, it turned out that the department of functional laboratory in relation to medical treatment enlarged the medical revenue very sharply. third, the intensive care units were being operated at the state of deficit, while other general wards were lucrative.

일부 농촌지역 학동의 B형 간염 감염률에 대한 조사 연구

최보율,김동준,박항배 한양대학교 의과대학 1986 한양의대 학술지 Vol.6 No.2

The positive rate of hepatitis B surface antigen (HBsAg) in Korea reported to be ranging from five to eleven per cent by the age composition, residential area of the group examined and by the method of study. As for the children, the positive rates reported were 4.5% (Kwon et al, 1977; of the pediatric patients hospitalized due to illnesses other than hepatic diseases), 4.2%, 4.8% (Hong et al, 1979 and Heon et al, 1983), 5.8% in farm villages and 2.9% in urban area (Kim et al, 1986). To grasp the rate and nature of hepatitis B virus infection in rural area of this country, authors examined 474 children in two elementary school and one middle school located in relatively isolated, remote agricultural district of the HBsAg and anti-HBs positive rates. The summary is as follows: 1. The overall positive rates of HBsAg and anti-HBs were 5.9% and 9.7% respectively. 2. While the positive rate of HBsAg didn't show the tendency to increase with age, that of anti-Hbsdid. 3. In age group below 14, the HBsAg positive rate was higheringirls than in boys but in 15 to 17 age group, the higher positive rate was noted among boys. Anti-HBs positive rate was higher in males throughout all age groups. 4. Since remarkably higher positive rates (both HBsAg and anti-HBs) were observed in certain villages, school or even in specific classes, one could conjecture that the source of infection was in those specific community and transmitted through close bodily contact between the children in, to and from the school.

Fabrication of 3-Dimensional LiMn2O4 Thin Film

Bo Gun Park,Jea Hyeok Ryu,Won Youl Choi,Yong Joon Park 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.3

3-Dimensionally ordered macroporous LiMn2O4 thin film was prepared by a sol-gel and dip coating method on Pt/Ti/SiO2/Si substrate. An opal structure consisting of mono dispersed polystyrene beads (300 nm) was used as a template. After solution containing Mn and Li precursors was coated on the template-deposited substrate, the template and organic materials in the precursors was removed by calcination at 400 °C . And then the 3-dimensional LiMn2O4 thin film with spinel structure was fabricated by heat treatment at 700 °C . The structural and electrochemical property was investigated by XRD, SEM and charge-discharge cycler.