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Myeong Seok Kim,Ya Seong Lee,Dong Kwan Kim,Yong Soon Kim,Jin Gyung Choi,Heung Gyu Park,Hyun Woo Kim,Seong Il Kim,Young Guk Kim,Chun Geun Park,Young Sup Ahn,Seon Woo Cha 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.10
Background : The purpose of this study was to big strong and root in the disease, many high quality seed of Achyranthes japonica N. selection by fostering, expanding the spread on a farm and raw materials medicines of sources deployment for process is to contribute to increasing farm income. Methods and Results : Collected variety into the mass selection breeding method by head-to-row cultivation, native variety of Hwasoon and Jangheung Jeonnam, was conducted in 2007. Three individual selection in 2010 as it produces the 27 and five individual in 2008 and 2009. From 2010 to 2011, pure line isolation as it cultivated and one foundation group. Promising in 2012, select one system. Replicated yield trial for two years beginning in 2013 a result of the stem length, multiple No. of branches and providing high -quality “No. 1, Jeollanam-do” majority by assigning system name. Naju-si, Yeongam-gun, local excellence by implementing a local adaptability test recognized in two years. To breed a new variety named as a dwelling “ Woogang” of Achyranthes japonica N. the review by fostering december 2015 to be registered. Conclusions : Leaf type is the broad lancet, flowering time is new variety two days than Jangheung native variety delayed. New variety of stem length and main root length are check variety (89㎝, 13.5㎝) of 9㎝ and 2㎝ tall respectively. Seed yields has native variety as much as 35 % compared to the many into 43.5 kg/10a. The ecdysteroids contents of roots was 1.2 times higher compared to check variety (668.1ppm). The dried root yields of the new variety are 285kg/10a a many native variety than 20%.
차기철 ( Cha Gi Cheol ),유영욱 ( Yu Yeong Ug ),이명규 ( Lee Myeong Gyu ),김동진 ( Kim Dong Jin ),유익근 ( Yu Ig Geun ),엄태규 ( Eom Tae Gyu ) 한국물환경학회 2003 한국물환경학회지 Vol.19 No.5
The relationship between SMP (soluble microbial products) and membrane fouling in the MBR (submerged hollow-fiber membrane bio-reactor) was investigated. The phenol was used as a substrate. The MBR was performed under condition that SMP concentration is changed from 20㎎/L to 60 ㎎/L. The membrane fouling increased with increasing of SMP concentration. The effect of resistance values on the membrane fouling was the order of R_(c)>R_(g)>R_(f)>R_(m). The increase of viscosity and non-biodegradable matters in the MBR was closely connected with the SMP concentration. The concentration of SMP should be kept less than 40 ㎎/L for stable operating of MBR. The T_(max) (time for maximum) decreased with increasing of SMP concentration. The removal rate of organic matters and total nitrogen in the MBR showed over 98% and 90%, respectively.
김명수 ( Kim Myeong Su ),오근태 ( O Geun Tae ),이동하 ( Lee Dong Ha ),차상원 ( Cha Sang Won ) 대한설비관리학회 2003 대한설비관리학회지 Vol.8 No.4
N/A Accelerated degradation is concerned with models and data analyses for degradation of product performance over time and at overstress and design condition. This paper presents an accelerated degradation model of adapters used for notebook E. It is assumed that output voltages of adapters degrade over time and their degradation rate is affected by temperature. An accelerated test is planned and implemented at three levels of temperature, and output voltages are measured periodically to estimate the degradation model. Based on the plot of test data, a degradation model is assumed which is based on the Anhenius model. Regression analysis is used to estimated the model, and analysis of variance is made to verify the significance of regression model. From the estimated model, the failure tjmes and acceleration factor are obtained.
Hahm, Eunil,Cha, Myeong Geun,Kang, Eun Ji,Pham, Xuan-Hung,Lee, Sang Hun,Kim, Hyung-Mo,Kim, Dong-Eun,Lee, Yoon-Sik,Jeong, Dae-Hong,Jun, Bong-Hyun American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.47
<P>Surface-enhanced Raman scattering (SERS) spectroscopy is attractive in various detection analysis fields. However, the quantitative method using SERS spectroscopy remains as an area to be developed. The key issues in developing quantitative analysis methods by using SERS spectroscopy are the fabrication of reliable SERS-active materials such as nanoparticle-based structures and the acquisition of the SERS signal without any disturbance that may change the SERS signal intensity and frequency. Here, the fabrication of seamless multilayered core-shell nanoparticles with an embedded Raman label compound as an internal standard (ML<SUB>RLC</SUB> dots) for quantitative SERS analysis is reported. The embedded Raman label compound in the nanostructure provides a reference value for calibrating the SERS signals. By using the ML<SUB>RLC</SUB> dots, it is possible to gain target analyte signals of different concentrations while retaining the Raman signal of the internal standard. The ML<SUB>4-BBT</SUB> dots, containing 4-bromobenzenethiol (4-BBT) as an internal standard, are successfully applied in the quantitative analysis of 4-fluorobenzenethiol and thiram, a model pesticide. Additionally, ratiometric analysis was proved practical through normalization of the relative SERS intensity. The ratiometric strategy could be applied to various SERS substrates for quantitative detection of a wide variety of targets.</P> [FIG OMISSION]</BR>
돼지 관상동맥 스텐트 재협착 모델에서 Carvedilol 부착 Biodiv Ysio(TM) 스텐트의 신생내막 증식 억제 효과
김원 ( Kim Won ),정명호 ( Jeong Myeong Ho ),차광수 ( Cha Gwang Su ),이승현 ( Lee Seung Hyeon ),홍영준 ( Hong Yeong Jun ),김주한 ( Kim Ju Han ),안영근 ( An Yeong Geun ),박옥영 ( Park Og Yeong ),김무현 ( Kim Mu Hyeon ),조정관 ( Jo 대한내과학회 2004 대한내과학회지 Vol.66 No.1
목적 : Carvedilol은 알파 및 베타수용체 차단제로서 혈관 평활근 세포의 이동과 증식을 억제하며, 동물실험에서 신생내막의 증식을 효과적으로 억제하였다. 저자 등은 돼지 관상동맥 스텐트 재협착 모형을 이용하여 carvedilol 부착 스텐트의 스텐트 내 신생내막 증식 억제와 스텐트 재협착의 예방에 대한 효과를 알아보고자 하였다. 방법 : 실험용 동물은 25~35 kg의 암돼지를 aspirin과 ticlopidine으로 전처치하고, 확립된 방법을 이 Background : Carvedilol is a beta- and alpha-receptor blocker, a direct inhibitor of smooth muscle cell proliferation and migration, and produces a significant suppression of neointimal hyperplasia in rat carotid injury model. We tested whether carvedilol
Jeong, Sinyoung,Park, Ji Yong,Cha, Myeong Geun,Chang, Hyejin,Kim, Yong-il,Kim, Hyung-Mo,Jun, Bong-Hyun,Lee, Dong Soo,Lee, Yoon-Sik,Jeong, Jae Min,Lee, Yun-Sang,Jeong, Dae Hong Royal Society of Chemistry 2017 Nanoscale Vol.9 No.7
<P>Antibody-conjugated nanoparticles (NPs) have attracted great attention in diagnostic and therapeutic applications due to their high sensitivity and specificity for biotargets, as well as their wide applicability. Unfortunately, these features are significantly affected by antibody conjugation methods in terms of conjugation efficiency, orientation of the target binding site in the antibody, and denaturation during chemical conjugation reactions. Furthermore, the number of conjugated antibodies on each NP and the overall targeting efficacy are critical factors for a quantitative bioassay with antibody-conjugated NPs. Herein, we report a versatile and oriented antibody conjugation method using copper-free click chemistry. Moreover, the number of conjugated antibodies and their binding capacity were quantitatively and experimentally evaluated using fluorescently-labeled antibodies and antigens. The strong binding capability of antibody-conjugated NPs prepared using the copper-free click chemistry-based conjugation strategy was 8 times superior to the binding capability seen following the use of the EDC/NHS-coupling method. Additionally, the versatility of the developed antibody conjugation method was also demonstrated by conjugation of the antibody to three kinds of silica-encapsulated NPs.</P>