白毛藤엑기스가 白鼠의 實驗的 肝臟障碍에 미치는 影響

文永熙,姜壽鐵 조선대학교 약학연구소 1989 藥學硏究誌 Vol.11 No.1

In order to study the effect of extracts of Solanum lyratum Thunberg on the liver damage of the rats intoxicated with CCl^4, the activities of GPT, GOT, Al.P, LDH and the levels of total cholesterol, total bilirubin in serum were measured. The results were as follow: The extracts (M-Ex, W-Ex.) wee showed to be significanfty decrease in the activities of GPT and GOT in serum rats intoxicated by CCl_4. The Al.p activity was significantly decreased on the 2nd day after administration of the extracts. The LDH acticity was significantly decreased in all sample groups, but W-Ex was more decreased than M-Ex. The level of total cholesterol and total bilirubin was showed to be signicantly decreased on the 2nd and 4th days after administration of M-Ex., but W-Ex. was not influenced, when copared with control group. Acording to the above results, it is thought that the extract of Solanum lyratum improves the hepatic function in the CCl_4-infoxicated rats.

퍼지 이론을 이용한 다 개체 지능형 시스템의 동기화 제어기 설계 및 구현에 관한 연구

文熙根,金永卓,金秀貞,金寬衡,李尙培 한국해양대학교 산업기술연구소 2003 연구논문집 Vol.20 No.-

이 논문의 주제는 시스템의 두 DC 모터의 동기화를 위한 효과적인 PWM 듀티비 조절이다. 퍼지 제어기는 많은 불확실하고 복잡한 산업 공정에 성공적으로 적용되어왔다. 그래서 만약 목표지점의 길이가 다르다면 속도 조절을 위한 PWM 듀티비 조절을 위해 언어적인 퍼지 규칙을 이용한 퍼지 제어기를 적용했다. 그리고 미지의 플랜트를 위한 퍼지 제어기법을 이용한 미지의 변환 함수 시스템을 연구했다. 이 제어기는 시스템 동기화를 위한 PWM 듀티비 제어에 성공적으로 적용되어지고 있다. The subject of this paper is to control efficient PWM duty for two DC motor synchronousness in the system. Fuzzy controller have been successfully applied to many uncertain and complex industrial plant. So, It adapted fuzzy controller using compositional fuzzy rule so that change PWM duty for speed control if the length of destination is different. And for unknow plant, it is the study to make the unknow transfer function system with fuzzy control method. This controller has been successfully applied to PWM duty control for the system synchronousness.

포도알균 균혈증 환자에서 사망 예측 위험인자

문수연,이미숙,손준성,이희주,이상오 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

Background : Staphylococcus aureus is a common cause of severe infection and frequently results in death or disability. We investigated potential risk factors influencing clinical outcome in S. aureus bacteremia (SAB). Materials and Methods : Our study is based on retrospective chart review for episodes of SAB from 168 patients, identified between January 2003 and December 2005. Twenty patients were excluded: 2 patients with infective endocarditis and 18 patients with metastatic lesions. Demographic, underlying diseases, sources of SAB, antimicrobial therapy, laboratory, and microbiologic characteristics were identified. Outcome was classified as death or survival 12 weeks after onset of SAB. Results : A total of 97 patients had survived and 51 patients died 12 weeks after the onset of SAB. Death group was older (66.4±13.6 vs. 59.4±14.9 years, P=0.007) and had higher Acute Physiology and Chronic Health Evaluation II system score (17.5±6.3 vs. 13.5±5.1, P<0.001) and the acute physiology score (11.1±5.5 vs. 8.0±4.3, P<0.001). Patients with nosocomial SAB (36 (70.6%) vs. 49 (50.5%), P=0.03] and ineradicable primary source of SAB (46 (90.2%) vs. 66 (68.0%), P=0.005] were more vulnerable to death. Multivariate analysis shows that hospital acquisition [adjusted odds ratio (OR)=2.93), ineradicable primary source (adjusted OR=5.74) and high APACHE II score (adjusted 0R=1.22) lead to higher mortality rate from SAB. Conclusion : Our study shows hospital acquisition, ineradicable primary source, and high APACHE II score are the risk factors related to death from SAB. On the other hand, methicillin resistance or initially ineffective antimicrobial therapy is not much correlated with mortality rate from SAB. 목적 : 황색포도알균은 중증 감염의 흔한 원인이며, 사망하거나 합병증이 발생하는 경우가 종종 있다. 본 연구를 통해 황색포도알균 균혈증 환자에서 임상적 결과에 영향을 미칠 수 있는 위험인자를 확인해 보고자 한다. 재료 및 방법 : 본 연구는 2003년 1월부터 2005년 12월까지 3년간 168 명의 환자에서 발생한 황색포도알균 균혈증에 대해 후향적 의무기록 조사를 바탕으로 이루어졌다. 성별, 나이, 기저 질환, 황색포도알균 균혈증의 원발 병소, 항생제 사용력과 미생물학적 특징에 대한 자료를 모았으며, 균혈증 발생 당시 질환의 중증도는 acute physiology score (APS)와 APACHE II 점수(acute physiology and conic health evaluation II system, APACHE II score)를 이용하여 측정하였다. 결과는 균혈증 발생 12 주 후 사망과 생존으로 나누어 분석하였다. 결과 : 황색포도알균 균혈증 발생 12 주 후 97명의 환자가 생존하였으며, 51명이 사망하였다. 사망 환자 군이 나이가 더 많았으며(66.4±13.6 vs. 59.5±14.9세, P=0.007), APACHE II 점수(17.5±6.3 vs. 13.5±5.1, P<0.001)와 APS (11.1±5.5 vs. 8.0±4.3, P<0.001)가 높았다. 병원 내 감염에 의한 황색포도알균 균혈증 환자[36 (70.62%) vs. 49 (50.5%), P=0.030]와 제거 불가능한 원발 병소를 지닌 경우[46 (90.2%) vs. 66 (68.0%), P=0.005] 사망위험성 이 높았다. 다 변량 분석에 의하면 병원 내 감염[adjusted odds ratio (OR)=2.93]과 제거 불가능한 원발 병소(adjusted OR=5.74), 높은 APACHE II 점수(adjusted 0R=1.22)에 의해 황색포도알균에 의한 사망률이 증가하였다 결론 : 본 연구에서 병원 내 감염과 제거 불가능한 원발 병소, 높은 APACHEH 점수가 황색포도알균 균혈증에 의한 사망과 관련된 위험인자이다. 반면, 메티실린 내성과 초기 부적절한 항생제 사용은 황색포도알균 균혈증의 사망률과 연관성이 없었다.

보우타이 패치 안테나의 초광대역화 설계

문수덕,박재일,최경,황희용 강원대학교 정보통신연구소 2005 정보통신논문지 Vol.9 No.-

In this paper, A ultra wideband antenna with electromagnetically coupled feeding is presented. The designed antenna is composed of Bow-tie patch with parasitic patch ground of a semicircular shape. The measured bandwidth of the designed antenna is from 2.5GHz to 8.3GHz for -10dB return loss (VSWR < 2). This antenna shows a similar radiation pattern of monopole and maximum gain better than ideal dipole throughout the operating frequency band.

다중 채널 동축 케이블의 초고주파 측정용 보드 설계

문수덕,김진규,황희용 강원대학교 산업기술연구소 2007 産業技術硏究 Vol.27 No.A

In High-Speed DSP systems, crosstalk between transmission lines of multi-channel can degrade the performance of equipment operations, This paper presents a microwave board to measure multi-channel coaxial cable assembly. The designed board has good performances from DC to 3 GHz, which have improved characteristic impedance, reduced crosstalk by using via fence, and low transmission loss. Using the designed board, we can measure characteristics of DUT(Device Under Test) such as return loss, insertion loss, crosstalk, phase delay, and characteristic impedance. The measured results are used to improve performances of a produced coaxial cable assembly.

운동종목에 따른 운동선수의 영양필요량 및 기호성에 준한 표준 식단의 컴퓨터 입력 프로그램 개발방법에 관한 연구

문수재,손경희,이동우,이영미 연세대학교 대학원 1986 延世論叢 Vol.22 No.1

본 연구는 각종 운동선수 대상의 설문조사를 기초로 하여 운동선수의 식생활 관리를 위한 전산화 프로그램을 제시하였다. 즉 1) 운동선수의 식기호를 통한 요구와 체급의 필요에 준한 각종 식단작성과 급식관리를 위한 전산화 프로그램을 작성하였다. 2) 이에 근거를 둔 영양상담 프로그램을 개발하기 위한 기초자료의 정리를 시도하였다. 기초자료 수집을 위해 실시한 16종목의 운동선수 232명을 대상으로 실시한 기호도 및 생활유형 분석조사의 결과는 대부분의 운동선수가 ① 규칙적인 생활을 하고 있었으며, 일일생활의 구성은 취침(7~8시간), 아침식사전 운동(1~1 1/2시간), 오전운동(2~3시간), 오후운동(2 1/2~3 1/2시간), 식사 및 휴식(5~7시간), 자유시간(1~3시간)으로 구성되어 있으며, ② 현재 식생활의 문제점은 단체급식시 급식시 제공되는 음식의 맛, 질적수준, 3끼 음식 분배량의 부적절성, 경기직전에 식사의 지나친 감량이나 증량을 지적하였다. ③ 조사대상으 88%가 장기적인 식사관리가 필요하다고 지적했으며, 경기력 향상을 위해 특별히 처방된 식사를 하는 선수는 전체의 43.5%로 처방식의 주종은 육류(단백질식품), 야채(비타민, 무기질식품), 그 이외 열량농축식품(지방, 캔디류)으로 구성되어 있었다. 처방식을 가지고 있는 주요 이유는 영양섭취를 개선시킴으로써 경기력 및 체력향상과 운동시에 condition조절이 가능하다는 점을 지적하였다. ④ 식품에 대한 기호성 조사에서는 대부분의 식품에 대해 극히 싫어하거나 기피하는 문제점은 없었다. 컴퓨터를 이용한 운동선수 대상의 식생활관리 프로그램 개발을 위해서 사용한 기기는 IBM-PC OA-16XT기종의 Personal computer였으며, 이 기기에서 이용가능한「Basic language」,「lotus」system, 「DBASE Ⅲ」를 이용하여 프로그램을 작성하였다. 프로그램 작성을 위해 선행한 연구로 ① 설문조사를 통하여 운동선수의 생활유형을 분석하여, 각 운동종목별 영양필요량 산출을 시도하였고, ② 한끼에 1,200Kcal를 공급할 수 있는 식단을 영양학적, 식품학적 견지에서 작성하였으며, ③ 식품별 자료처리가 용이하도록 식품교환단위의 설정 및 음식에 고유 번호를 부여하는 작업을 실시하였다. 프로그램은 ① 일일 섭취한 영양가 평가하는 프로그램 ② 운동종목, 체중, 성, 생활시간을 고려한 일일 필요 영양소량을 계산하는 프로그램 ③ 변화있고 다양한 식단작성 및 Recipe 제시 프로그램을 개발하였다.

Gel 狀 食品에 關한 실험조리적 검토 Ⅱ-응고제에 따른 두부의 Testure 특성을 중심으로

文秀才,孫敬喜 연세대학교 대학원 1980 延世論叢 Vol.16 No.2

Soybean curds were prepared using coagulants such as calcium sulfate, calcium chloride, magnesium chloride, glucono delta lactone and acetic acid. Their hardness was measured by a sensory method to develop a standard recipe. The textural characteristics of bean curds prepared by the standard recipe were measured by a texturometer and a penetrometer, and results there-from were used to establish a texture standard for soybean curd. Changes in the texture of soybean curd under different cooking conditions were surveyed by a penetrometer. Results obtained through the aforecited experiments are summarized as follows: The optimal concentration of coagulants for soybeancurd preparation was 1.84% for calcium sulfate, 1.05% for calcium chloride, 1.84% for magnesium chloride, 1.97% of glucono delta lactone and 0.48% of acetic acid. As the result of the sensory evaluation, the most acceptable soybean cued was determined to be one made with acetic acid. Other coagulants in the order of acceptability were magnesium chloride, calcium chloride, glucono delta loctone, calcium sulfate soybean curd, and commercial soybean curds. Through the objective examination of soybean curds by a texturometer and a penetrmoeter, it was found out that calcium sulfite soybean curd was the hardest, followed by glucono delta lactone, magnesium choloride, calciumchloride, and acetic acid soybean curd. Acetic acid soybean curd, the most acceptable, was 0.47TU, and calcium sulfate soybean curd, the least acceptable, was 1.73TU. Bean curds were put into distilled water and solutions of different concentration revels including salt, mono sodium glutamate, acetic acid, starch, and sodium carbonate. They were then boiled at the temperature of 100℃ for two, five, ten and twenty minutes, respectively, while their textural changes were observed by a penetrometer The hardness level of soybean curd texture in varying cooking conditions dropped sharply in five minutes of cooking. It then slowly rose or fell for ten minutes. From this point on, the level of hardness continued to decline in process of time. Accordingly, it is not necessary to boil soybean curd for more than ten minutes.

도금사업장의 작업환경의 유해인자 노출수준에 관한 연구

문덕환,도수영,이채관,황용식,선병관,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective : For the purpose of preparing the fundamental data and assessing the status of exposure level of chemical substances and physical agents. Methods and Material : Such as noise, two types of dust, four types of metals, seventeen types of organic solvents, and four types of other materials classified by specific chemical substances in 21 metal product plating factories classified by 28 processes. The author determined exposure level on those hazardous materials from Jan. to Dec. 2001. Results : The results were as follows: 1. The exposure level for noise was exceeded to Threshold Limit Value(TLV) in the process of 6 cases of Machining, 5 and 4 cases of pre and post-buffing, and 6 cases of waterdrop-removing, the mean noise level of all of processes was not exceeded to compliance level. 2. The exposure level for dust was not exceeded to TLV at all. 3. The exposure level for Chromium(Cr) was exceeded to TLV in Chromium plating process, metal exposure level including Zinc(Zn), Manganese(Mn), and Lead(Pb) was not exceeded to TLV. 4. The exposure level of toluene in case of organic solvents was exceeded to TLV in 1 case of finishing/cleaning, coating/developing process, respectively. 5. The exposure level of four types of other materials classified by specific chemical substances were not exceeded to TLV. 6. The exposure level for dust and metal including Zn, Mn, and Pb was decreased in comparison with two results of air monitoring performed. There was no difference of the exposure level for Cr, noise, and four types of other materials classified by specific chemical substances, and the exposure level for organic solvents was slightly increased. 7. The exposure level for noise in factories employing more than 21 workers was higher than that for noise in foadtories employing less than 20 workers. The more workers, the lower exposure level in metal including Zn, Mn. The exposure level for Cr was increasing in factories employing more than 51 workers, and the more workers the lower exposure level in organic solvents. Conclusion : According to above results, this study suggests positive work environment managements in processes exceeding exposure limit value as well as continuously consecutive work environment management in processes not exceeding exposure limit value and revealing no chronological difference of exposure level should be needed.

Sr·페라이트 플라스틱자석의 제조에 관한 연구

문현욱,최희태,서강수,신용진 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

In this paper, we mention he fabrication of Sr ferrite plastic magnet. In order to compose Sr ferrite, first, a little CaO, SiO₂, Na₂SiO₃, and Al₂O₃ are added to SrO5.9Fe₂O₃. Then, the composition is calcinated at 1225℃ under N₂ enviroment for 1 hourwith addition of PVA 5wt% solution. The carbon coating method increase grinding effect on powder fabrication. To fabricate anisotropic Sr ferrite plastic magnet, 80-89wt% of Sr ferrite and polyamide6 are kneaded and then 0-12kOe of magnetic field is applied. On magnet fabrication, an optimal condition of injection mold is obtained under the injection temperature 270℃, the injection pressure 120㎏/㎠, the magnetic field 8kOe and magnetic field applied time 8sec. As the result of experiments, we obtain (BH)max = 2.09MGOe property on anisotropic plastic magnet which is fabricated by using injection mold method in magnetic field.

경사 슬래브교의 지간/폭, 경사각에 따른 응력 상관성

남문희,정희효,이관희,이수경 慶尙大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.12 No.-

Skewed slab bridge have designed a width beam, stress of skewed slab bridge is quite different in according with skew and width /length. Especially in case that we analyse skewed slab bridge as a width beam, stress of right angle direction against axis of bridge is not analysed. In this study we will present the stress of transverse axis to longitudinal axis of bridge according to skew and width/length.