MANNOPROTEIN 과 GLUCAN 의 첨가가 쥐의 성장과 NATURAL KILLER CELL ACTIVITY 에 미치는 영향

손광수,조광근,최윤재,윤연화,김재영,한영근,문태현,김성찬 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.6

본 연구의 목적은 효모 세포벽, 또는 효모의 세포벽으로부터 본 연구에서 확립한 방법으로 분리한 mannoprotein(MP)과 glucan(Glu)을 동물에 급여하므로써 동물의 일당중체량, 일당사료섭취량과 사료:중체량의 비율, 그리고 동물이 가지고 있는 면역기능의 활성화정도를 조사하는데 있다. 산업적 측면에서 대량 추출하기 위하여 기존에 있는 방법을 개선하여 변형된 방법으로 효모세포벽제제를 분리하였다. 본 연구에서 분리된 효모세포벽제제(cell wall, mannoprotein glucan)와 시판중인 효모세포벽제제(Bio-Mos^(TM))를 0.1%로 4주령 횐쥐에 4주간 급여하였다. 일당중체량은 개선된 방법으로 분리한 glucan을 급여한 처리구에서 가장 높은 중체량을 나타냈으며, 다음으로 mannoprotein 급여구가 높았으며 cell wall과 시제품(Bio-Mos^(TM)) 급여구에서 낮은 중체량을 보였다. 일당사료섭취량에 있어서 glucan 급여구가 cell wall과 시제품 급여구들과 비교할 때 높았으며 사료:중체량 비율 또한 glucan 급여구에서 가장 좋은 경향을 보였다. 사양 4주깨 횐쥐로부터 spleen을 채취하여 YACl 세포에 대한 natural killer cell의 cytotoxicity를 분석한 결과 본 실험실에서 분리한 mannoprotein과 glucan이 면역 증진효과가 큰것으로 보였다. Mannoprotein 급여구와 glucan 급여구에서 대조구와 cell wall 급여구보다 면역 효과가 뚜렷하게 나타났으며(MP, P<0.01; Glu, P<0.05), mannoprotein 급여구가 glucan 급여구보다 natural killer cell의 활성도가 높았다(P<0.01). 결론적으로 효모세포벽, mannoprotein과 glucan을 횐쥐에 급여했을 때 성장능력에 있어서 유의성 있는 효과가 나타나지 않았지만 세포배양수준에서 spleen natural killer cell의 activity를 증가시키는 효과가 있다. The purpose of this study was to investigate the average daily gam, average daily feed intake, feed gain ratio and immune system activation of rats when feeding yeast cell wall, mannoprotein (MP) and glucan (Glu) which were isolated from yeast cell wall. In order to isolate the yeast cell wall products in large scale, we used the improved isolation method basing on the typical one. In this study, yeast cell wall products (cell wall, mannoprotein, glucan) and commercial product (Bio-Mos^(TM)) were fed to 4-week old rats by 0.l% during 4 weeks experimental period. Glucan(extracted from improved method) provided the highest average daily gain. Mannoprotein treated group showed the second highest average daily gain. Cell wall and Bia-Mos^(TM) fed groups showed lower average daily gain. Treatment fed glucan also showed higher average daily feed intake than that of cell wall and commercial Bio-Mos^(TM) groups. And in feed: gain ratio, glucan fed rats showed the respectively good results. At the 4th week of feeding trial, rats' spleens were obtained from all the treatments to evaluate the cytotoxicity of natural killer cell against YACl tumor cell. The results indicated that mannoprotein and glucan had the significant effects on activating immune system. Rats of mannoprotein and glucan treated groups showed the higher immune activity than that of cell wall and control groups (MP, P<0.01; Glu, P<0.05), and natural killer cell activity of mannoprotein fed rats was higher than that of glucan fed rats (P<0.01). In conclusion, although the addition of yeast cell wall, mannoprotein and glucan to the diet of rats did not provide the significant effects on growth performance, it was clear that the mannoprotein and glucan isolated in this study could stimulate the activity of spleen natural killer cell in the cell culture.

전신마취후 발생한 좌수 혈전성괴저

한민환,김정기,정태형,문영삼 대한마취과학회 1976 Korean Journal of Anesthesiology Vol.9 No.2

A 64-year-old female with earcinoma of esophagogastic junction developed gangrene of left arm after esophagogastrectomy to require amputation of the arm. The pateint had no known cardiac disorder before the operation but showed marked arrhythmia during the procedure. The general anesthesia was carried out with penthothal-succinylcholine induction and maintenance with N2O-O2-halothane.

한국(韓國)의 문화(文化) : 문화로 읽는 근대 이행기 매체문학 -『년한반도(年韓半島)』를 대상으로-

문선영 ( Tae Moon Han ),한태문 ( Sun Young Moon ) 한국사상문화학회 2010 韓國思想과 文化 Vol.51 No.-

이 논문은 한국의 근대 매체인 『少年韓半島』를 통해 한국 근대 이행기 매체문학의 정체성을 살펴보려는 의도 아래 기획 집필된 것이다. 이 때 중심되는 화두는 `문화`이다. 근대 이행기를 배경으로 한 매체문학을 대상으로 당대 문화 풍속도를 고찰하고자 하였다. 『少年韓半島』는 1906년 11월 1일 창간되었고, 1907년 4월 통권 6호로 종간되었다. 『年韓半島』는 국민정신을 함양하고 신지식을 선도하는 데 발간 목적을 두었다. `민주 정체(民主 政體)`를 새로운 국가상으로 삼고 있으며, 국민의 자질을 갖추기 위해서 무엇보다 `지식`의 습득이 우선되어야 함을 강조했다. <『少年韓半島』와 문화의식>은 `문화` 코드를 중심으로 한국 근대 매체의 정체성 문제를 집중적으로 다룬 것이다. 연구 대상이 『少年韓半島』인만큼, 문화의 범주로는 아이 또는 청소년들을 중심으로 한 일상문화와 기저문화에 주목했다. 여기서 당대 소년들의 삶의 동선과 민족주의 그리고 계몽주의를 통해 당대 문화의식을 도출하였다. 무엇보다 `교육`에 방점을 둔 문화적 풍속도가 두드러진다. 『少年韓半島』는 근대 학지(學知)를 다양하게 소개함으로써 아이들에게 삶의 좌표 설정과 문화적 판도를 깨우치게 하고, 나아가 이후 발간되는 『소년』, 『청춘』 등 본격적인 아동 또는 청소년 잡지의 시대를 연 종합지로서 의의를 지닌다. 그러나 이제껏 『少年韓半島』의 원본이 공개되지 않아 본격적인 연구가 이루어지지 못한 학계의 사정을 감안할 때, 본고는 되도록 그 낱낱을 헤아리려 했다. `신대한(新大韓)` 또는 `신대한을 건설할 주체`의 표상으로 `소년`을 전면에 내세우고 있는 만큼, 이를 중심으로 근대이행기의 문화 풍속 담론의 정체성을 해명하는 데 바쳐져 있다. This paper was written in the purpose of examining the identity of the media literature in the transitional period to modern ages in Korea by The Boy Han Peninsula. The topic of discussion is "culture." This paper tries to reflect on the cultural manners and customs in those days making the media literature which are based on the transitional period to modern ages as the object. The Boy Han Peninsula was launched on 1 Nov 1906 and ceased to be published in April of 1907, totally making 6 volumes. It was published in order to cultivate the spirit of the nation and lead the new set of knowledge. It takes the `political body of democracy` as the new portrait of the country, and emphasized that the learning of `knowledge` must be preceded for the preparation of the capabilities of the nation. `The Cultural Consciousness Appearing in The Boy Han Peninsula` focusedly dealt with the problem of the identity of media in modern Korea, mainly by the code of `culture`. As its title suggests, its cultural category directs its attention to the culture of ordinary lives of children and juveniles and their subculture. It induces the cultural consciousness of those days by those predicates of the lives of the boys of those days, nationalism and illumine. The cultural manners and customs of those days is especially marked by its drive toward education. The Boy Han Peninsula introduced various academic knowledge of modern times to awaken the children to the problem of setting proper coordinates in their lives and to the cultural territory of those days, and performed its role of pioneers who opened up the era of child or juvenile magazines which successively followed up like Boy, Youth and others. As its research object is The Boy Han Peninsula, before anything else, this paper is dedicated to explain the identity of the literary history of the modern ages in Korea as a discourse on the cultural manners and customs of the transitional period to modern ages by reflecting on the cultural manners and customs of that transitional period to modern ages, mainly by children that `Purpose` in the first volume makes `boyhood` stand for, or the symbol of the leader who will establish, the New Great Han.

A Study on Reimbursement Mechanism and the use for Exporters

Han,Ki Moon 韓國貿易商務學會 2010 貿易商務硏究 Vol.48 No.-

In letter of credit arrangements, the issuing bank nominate a reimbursing bank which serves as a source of funds payment to the beneficiary. The reimbursing bank could be 3rd party bank or the issuing bank itself. In view of working capital requirements, most beneficiary want to get export proceeds in advance through nominated banks and therefore letter of credit usually permit the beneficiary to negotiate drafts, accompanied by required documents, to nominated bank. If the credit is available with the nominated bank, there must be a reimbursement instruction in the credit, because in this method of availability the issuing bank is obliged to reimburse the nominated bank if that bank acts on its nomination There are legal relationship among issuing bank, nominated bank and reimbursing bank with regard to reimbursement activities. Related rules are UCP and URR and UCC (in case of USA). Korean exporters and bankers do not appear to know well the role of reimbursement and usage. 3 cases (court case + ICC Opinion + bad practices) were employed to study the reimbursement mechanism and suggest better usages. The beneficiary is strongly recommended to know the benefit of reimbursement claim from independent reimbursing bank. The benefits include speed payment (thereby saving finance costs) and safe funds (in case of stop payment by the issuing bank right after the proceeds are reimbursed). And further the beneficiary banks (being nominated or claim banks) are also recommended to take advantage of the 3rd party reimbursement in view of the cases illustrated.

근대전환기 역사, 전기 단형서사의 언론 매체별 비교 연구

문한별 ( Han Byoul Moon ) 한국문학교육학회 2011 문학교육학 Vol.35 No.-

Comparative Study on the Short Narratives in the Newspapers and Journals in the Transitional Period to Modern Era in Korea Moon, Han-Byoul There are different forms of short narratives in the newspapers and journals in the transitional period to modern era in Korea. Among them, the short narratives dealing with historical figures home and abroad are based on "Jeon(傳)", a traditional narrative form. However, clear differences are being shown between the newspapers and journals. In the journals, the narratives closely follow the structure and form of "Jeon". The narratives in the newspapers still have the characteristics of "Jeon". However, as they are under the categories such as "editorial" and "novel", which are not related to "Jeon", certain discrepancies exist between form and purpose. It means that the short narratives in the newspapers are being utilized for other values besides the ones represented by the historical figures in "Jeon" Meanwhile, the short narratives in the journals maintains the existing form while the ideology reflects the transition period to modern era, which clearly shows contents and purposes precede forms in the journals. As such, the short narratives show similarities and differences depending on the purposes and values of the media. The paper aims to go beyond a unilateral view on the short narratives in this era by highlighting such differences.

근막 결손의 복원과 자궁천골인대 고정을 통한 전자궁적출술 후 질탈출의 성공적 교정

문화숙(Hwa Sook Moon),최진국(Jin Koo Choi),김경서(Kyung Seo Kim),박근식(Kyun Sik Park),황지영(Ji Young Hwang),문성은(Sung Eun Moon),한지원(Ji Won Han),김상국(Sang Gook Kim),김상갑(Sang Gap Kim) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.7

목적 : 본 연구는 전자궁적출술 후 질탈출을 부위-특이적인 결함의 개념에 입각하여 치골경부 근막과 직장질 격막의 연결을 통한 골반내 근막의 복원과 자궁천골인대 고정술을 이용한 질탈출의 성공적인 수술적 교정의 방법과 결과를 보고하고자 한다. 연구 방법 : 1999년부터 2001년 8월까지 자궁적출술 후 질궁탈출 증상으로 문화병원 산부인과를 내원, 탈출된 질의 근막을 재건시킨 다음, 이를 자궁천골인대에 고정시킴으로써 질의 부위-특이적인 교정술을 받은 3명의 환자를 대상으로 하였다. 3명중 1명은 개복술을 하였고 2명은 내시경 수술을 하였다. 결과 : 환자의 연령 분포는 49-67세였으며, 수술시간은 평균 113분 (105-125)이었다. 세 환자 모두 수술 후 질의 상태가 해부학 및 기능적으로 정상이었으며, 9일째 특이사항 없이 퇴원하였다. 수술 후 HRT를 시행한 1명을 포함한 3명 모두 각각 24개월, 12개월, 7개월간의 추적 검사에서도 특이한 합병증이나 재발 없이 좋은 경과를 보였다. 결론 : 골반 근막 결손의 복원과 자궁천골인대 고정술은 전자궁적출술 후 질탈출의 교정에 매우 안전하고 효과적이며, 기능적인 방법으로 사료되며, 자궁천골인대를 질탈출 교정에 이용한 연구는 본 연구가 국내에서 처음이다. Objective : To report the method and efficacy of the site specific-defects repair in the endopelvic fascia and uterosacral ligament suspension for the correction of posthysterectomy vaginal vault prolapse. Methods : This study was performed in 3 patients with posthyterectomy vaginal vault prolapse who underwent the surgery for the reconstruction of endopelvic fascia and the correction of vault prolapsed vagina by using uterosacral ligament suspension at the department of Obstetrics and Gynecology in Moon-Hwa Hospital. Among them, 1 patient was treated by laparotomy, and 2 patients were treated by laparoscope. Results : The age of patients ranged from 49 to 67 years. The mean operation time was 111 minutes (105-120 minutes). The status of postoperative vagina was normal in all 3 patients, who were discharged 9 days after operation without symptoms. No complication or recurrence were found in them despite long-term follow-up for 24 months, 12 months, 7 months, respectively after operation. One patient has been treated with HRT therapy. Conclusion : The reconstruction of the defect of endopelvic fascia and uterosacral ligament fixation may be very safe, effective, and functional in the correction of vaginal vault prolapse. This study reports the treatment of vaginal vault prolapse using uterosacral ligament within Korea for the first time.

자연과학적 데이터를 활용한 풍납토성 백제토기의 분류 방안 연구

문은정 ( Eun Jung Moon ),강희준 ( Hee Jun Kang ),한민수 ( Min Su Han ),이한형 ( Han Hyoung Lee ) 백제학회 2011 백제학보 Vol.0 No.5

본 연구는 풍납토성 출토 백제토기를 대상으로 현장에서 소성온도에 따라 토기를 분류할 수 있는 외형관찰 기준을 마련하는데 자연과학적 데이터를 활용하고자 하는 연구이다. 소성온도는 토기의 경도, 밀도 풍을 포함한 다양한 물리화학적 특성에 영향을 미친다. 이 중 현장에서 측정이 가능하고 유용한 것이 경도이다. 그러므로 우리나라의 발굴현장에서 적용하고 있는 경도 측정기준을 적용하여 토기를 분류하고, 자연과학적 분석을 통하여 이들 토기의 마이크로비커스 경도, 밀도, 흡수율, 조직의 유리질화도, 광물학적 특성 등을 측정하여 현장에서 적용하는 경도분류 기준과의 상관관계를 비교연구하였다. 그 결과, 발굴현장에서 동전의 긁힘에 의해 주로 행해지던 연질과 경질의 이분법적 분류는 연질과 연경질, 경질의 세 단계로 세분됨을 알 수 있었다. 소성 온도 추정 결과, 연질은 1,000˚C 이하, 연경질은 1,000~1,100˚C, 경질은 1,200˚C 이상에서 소성되었을 것으로 판단된다. 한편, 3단계로 분류되는 토기들의 각 단계별 외형적 공통점을 추출하여 자연과학적인 정밀분석 없이 육안관찰만으로 토기를 3단계로 분류할 수 있는 관찰기준의 제시를 시도하였다. 이러한 기준은 파괴분석을 하지 않고도 토기의 외형적 특징을 이용하여 토기의 대략적인 물성과 소성온도 추정을 가능하게 할 것으로 기대된다. 단, 이러한 기준은 풍납토성에서 출토된 한성백제시기의 토기 중에서 배류와 호류 등 색상이 단조로운 제한된 기종을 중심으로 한 결과라는 한계를 가진다. 따라서 추가적으로 여러 기종의 다양한 색상을 가진 토기들을 대상으로 풍납토성 출토 토기의 경도별 분류가 가능하도록 수정·보완하는 연구를 진행할 예정이다. Observation methods of appearance were studied to establish a systemized classification criteria according to the firing temperatures of excavated earthenware from the Pung-Nap Mud Castle. A firing temperature has an impact on various physical and chemical properties including hardness and density of earthenware. Of all the properties, hardness can be measured in situ. Therefore, the earthenware were categorized according to the measurement method of hardness which can be applied and useful method for archaeological sites. In addition, the correlation between the measurement method and micro Vickers hardness, absorptance, degree of vitrescence and mineralogical properties of the earthenware were studied by means of a natural scientific analysis. The result suggests that the dichotomous way of classification based on a scratching method determining whether it is hard or soft should be categorized into three stages; soft, soft/hard and hard. According to the presumption of the firing temperature, it is believed that the earthenware were fired at below 1,000℃, 1,000~1,100℃ and 1,200℃ respectively. The systemized observation method was proposed to enable the earthenware to be categorized into three stages using visual observation without a detailed scientific analysis. The method will make it possible to estimate roughly the physical properties and firing temperature of the earthenware with only visual observation. However, it has limits as it was established focusing on certain types such as Cups and Jars among the Han-Sung Baek-Je earthenware. Therefore, a further study is planned to be carried out on various objects excavated from Pung-Nap Mud Castle in order to enable categorization on the basis of hardness of the earthenware.

New method for an evaluation of the esthetical improvements resulting from a mandibular angle reduction

Joo-Hwan Kim,Se-Jin Han,Moon-Young Kim 대한구강악안면외과학회 2017 대한구강악안면외과학회지 Vol.43 No.4

Objectives: This paper proposes Han’s ratio as an objective and quantitative comparative result obtained from pre and postoperative data in patients with a mandibular angle reduction. Materials and Methods: Thirty patients, 12 men and 18 women, who visited the Department of Oral and Maxillofacial Surgery with the chief com-plaints of skeletal mandibular prognathism and prominent mandibular angle were selected. The subjects were classified into 3 groups according to the types of surgical procedures involved. Group A consisted of patients who underwent mandibular angle resection and mandibular setback. Group B was comprised of patients with mandibular angle resection, mandibular setback and genioplasty. Group C consisted of patients with mandibular angle resection, mandibular setback, Le Fort I osteotomy, and genioplasty. The landmarks placed in pre and postoperative frontal photographs were used to obtain the Han’s ratio in each group. The Han’s ratios were compared pre- and postoperation and according to the surgical techniques applied. Results: Of the 3 groups who had undergone a mandibular angle resection, all showed a statistically significant increase in Han’s ratio. On the other hand, there was no statistically significant difference based on the surgical techniques used. Conclusion: The ratio of the lateral lower face proposed in this study is a potential indicator of postoperative esthetic enhancement in mandibular angle reduction surgery.

한강둔치에서 재배된 농작물 중의 미중금속 함량에 관한 연구

김연천,전옥경,양혜란,최영희,한선희,이강문,Kim, Youn-Choen,Chun, Ock-Kyoung,Yang, Hae-Ran,Choi, Young-Hee,Han, Sun-Hee,Lee, Kang-Moon 한국식품위생안전성학회 2000 한국식품위생안전성학회지 Vol.15 No.3

한강 고수부지 및 지천인 안양천, 탄천, 중랑천변의 경작지에서 채집된 36종 285건의 농작물에 대한 Pb, Cr, Cd, Fe, Zn, Mn, Cu. Hg의 농도를 측정하고 그 결과를 채집 시기, 채집 지역 및 작물별로 비교, 분석한 결과, 작물 중의 중금속 함량은 평균치를 기준으로 볼 때 Fe(34.592 ppm)>Mn(11.071 ppm)>Zn(8.853 ppm)>Cu(1.795 ppm)>Cr(0.237 ppm)>Pb(0.100 ppm)>Cd(0.011 ppm)>Hg(0.003 ppm) 순으로 곡류 및 두류에서는 Zn의 함량이 Mn보다 높고, 채소류와 과실류에서는 Mn의 함량이 Zn보다 높은 양상을 나타냈다. 또한 각 지역에서 채취한 작물의 미량금속 함량의 경우 Fe은 0.004∼203.083 ppm, Cu은 0.017∼22.727 ppm. Mn은 0.000∼74.373 ppm. Zn은 0.080∼37.166 ppm으로 비교적 고농도로 존재하고 있는 반면 유해중금속류인 Pb은 0.000∼0.654 ppm, Cd은 0.000∼0.270 ppm, Cr은 0.000∼l.229 ppm, Hg은 0.000∼0.037 ppm으로 비교적 미량으로 존재함을 알수 있었다. 대상 농작물을 잎, 줄기, 뿌리, 열매로 분류하여 미량금속 함량을 분석한 결과, 분석 대상 금속의 농도가 잎>줄기>뿌리>열매의 순으로 나타났다. 무등의 뿌리 작물에 있어서 Pb은 잎(0.055 ppm))뿌리(0.035 ppm), Cr은 잎(0.118 ppm))뿌리(0.031 ppm), Cd은 잎(0.004 ppm)1뿌리(0.001 ppm), Hg은 잎(0.004 ppm))뿌리(0.001 ppm)으로 뿌리보다 잎에 많은 것으로 나타났는데 이러한 결과로 보아 뿌리는 금속 이온이 흡수되는 기관일 뿐 축적은 잎에 비해 상대적으로 적게 됨을 알 수 있었다. This study was conducted to determine the content of trace metals in crops cultivated in Han-riverside, Anyang stream, Tan stream, and Jungryang stream. Trace metals (Pb, Cr, Cd, Fe, Zn, Cu, Hg) were detected in 36 crops, 285 samples by Atomic Absorption Spectrophotometer and Mercury Analyzer. The average concentration of trace metals in crop samples was in the order of Fe (34.592 ppm)>Mn (11.071 ppm)$\geq$Zn(8.853 ppm)>Cu(1.795 ppm)>Cr(0.237 ppm)>Pb(0.100 ppm)>Cd(0.011 ppm)>Hg(0.003 ppm). In crop samples, the contents of Fe, Cu, Mn, and Zn, which ranges were 0.004-203.083 ppm, 0.017~22.727 ppm, 0.000~74.373 ppm, 0.080~37.166 ppm, respectively, were relatively higher than those of Pb, Cd, Cr, and Hg, which ranges were 0.000~0.654 ppm, 0.000~0.270 ppm, 0.000~l.229 ppm, 0.000~0.037 ppm, respectively. The concentration of trace metals in crop samples was in the order of leafy vegetables > stem vegetables > root vegetables > fruity vegetables. In the root vegetables, such as radish, the content of Pb was leaf(0.055 ppm)>root(0.035 ppm), that of Cr, leaf (0.118 ppm)>root(0.031 ppm), that of Cd, leaf(0.004 ppm)>root(0.001 ppm), that of Hg, leaf(0.004 ppm)>root(0.001 ppm). As the results, it could be thought that root is the organ which doesn't accumulate the heavy metal ions, but absorb them.

한우고기의 브랜드 자산이 구전의도 등과의 관계성에 대한 탐색적 연구 - 신뢰와 친밀감의 매개효과를 중심으로 : 한우고기의 브랜드 자산이 구전의도 등과의 관계성에 대한 탐색적 연구

김용만(Kim Yong Man),한일문(Ill Moon Han) 한국마케팅과학회 2006 한국마케팅과학회 학술대회 발표 논문집 Vol.- No.-

This research is investigated theoretical background of influence the influential factors of components of brand equity that is the quality, advertisement, well-being factors to the components of brand equity that is the perceived quality, the brand association, the brand awareness. This investigation was conducted to see the relationship between the words of mouth attitude, that is, outcome effector and the brand loyalty get through the trust and intimacy that is the mediation factor of Han-Woo beef. So, hereafter the more investigation of the influence the influential factors of components of brand equity to the components of brand equity and the relationship between the influential factors of components of brand equity and mediation factor that is trust and intimacy will be conducted. And, the relationship between the customer"s trust, the intimacy outcome effector that is the words of mouth and brand loyalty will be verified.