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      • KCI등재

        Fabrication of a water-retaining, slow-release fertilizer based on nanocomposite double-network hydrogels via ion-crosslinking and free radical polymerization

        Yanmin Shen,He Wang,Zijun Liu,Weikun Li,Yuhua Liu,Jingjing Li,Hong-Liang Wei,Huayun Han 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.93 No.-

        A new type of water-retaining, slow-release fertilizer (WSF) based on double-network hydrogels wasfabricated via the ion-crosslinking of sodium carboxymethyl cellulose and the free radical polymeriza-tion of polymerizable β-cyclodextrin (MAH-CD), polyethylene glycol dimethacrylate (PEGDA), acrylamide(AM), and acrylic acid (AA) with urea-loaded halloysite as an additive. The effects of the AM to AAmonomer ratio, the halloysite content, the AlCl3 content and the MAH-CD content on the swelling ratiowere studied. Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), andthermogravimetric analysis (TGA) were applied to characterize the structure and properties of the WSF. The swelling behavior and water retention capacity of the fertilizer were investigated using a classicgravimetric method. The experimental results indicated that the presence of halloysite nanotubes clearlyadjusted the swelling and release properties of the WSF. Kinetic modeling indicated that the swellingmechanism and slow release behavior were consistent with a Fickian diffusion mechanism. Form theconsiderations of its properties and raw materials, the fertilizer developed here has a good prospect ofapplication and extension.

      • KCI등재

        New stability analysis for generalized neural networks with interval time-varying delays

        Yanmin Liu,Junkang Tian,Zerong Ren 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.4

        This paper deals with the problem of delay-dependent stability for neural networks with interval timevaryingdelays. First, we divided delay interval into two parts. Second, a new Lyapunov-Krasovskii functional isconstructed, and relationships between the augmented state vectors have been fully considered, which may yieldless conservative results. Third, based on free-matrix-based integral inequality method and reciprocally convextechnique, some new less conservative delay-dependent stability criteria have been obtained by combining with thenew Lyapunov-Krasovskii functional. Finally, two numerical examples are given to show the effectiveness of thederived conditions over the existing ones.

      • KCI등재

        H2O2 regulates root system architecture by modulating the polar transport and redistribution of auxin

        Chao Su,Liu Liu,Haipei Liu,Brett J. Ferguson,Yanmin Zou,Yankun Zhao,Tao Wang,Youning Wang,Xia Li 한국식물학회 2016 Journal of Plant Biology Vol.59 No.3

        The accumulation and redistribution of the plant hormone auxin plays a crucial role in root development and patterning. Plants can alter their root system architecture (RSA) to adapt to different biotic and abiotic stresses. In addition, reactive oxygen species (ROS), such as H2O2, are known to increase in plants undergoing stress. Here, we present evidence that H2O2 can regulate auxin accumulation and redistribution through modulating polar auxin transport, leading to changes in RSA. Plants exposed to different concentrations of H2O2 formed a highly branched root system with abundant lateral roots and a shorter primary root. Monitoring of the auxin responsive DR5::GUS indicated that auxin accumulation decreased in lateral root primordia (LRP) and emerging lateral root tips. In addition, polar auxin transport, including both basipetal and acropetal transport modulated by AUX1 and PIN protein carriers, was involved in the process. Taken together, our results suggest that H2O2 could regulate plastic RSA by perturbing polar auxin transport as a means of modulating the accumulation and distribution of auxin.

      • KCI등재

        Optimization of Stamping Process Parameters Based on Improved GA-BP Neural Network Model

        Yanmin Xie,Wei Li,Cheng Liu,Meiyu Du,Kai Feng 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.7

        Reasonable process parameters are the key measures to ensure the quality of stamping products. In order to reduce the risk of cracking and wrinkling of stamping products, an improved genetic algorithm is proposed and used to optimize the weights and thresholds of the BP neural network(BPNN). A surrogate model combining an improved genetic algorithm and BPNN(IGA-BPNN)is developed. Taking double C as the research object, the training samples and test samples are extracted through Latin hypercube. The training output of IGA-BPNN model is obtained by AutoForm simulation, and the mapping relationship between process parameters and forming quality is established. Then the mapping relationship is optimized by IGA to obtain the optimal process parameters. The results show that this method reduces the wrinkling of the flange edge of double C and obviously improves the forming quality.

      • KCI등재

        Experimental Study on Mechanical and Durability Properties of Glass and Polypropylene Fiber Reinforced Concrete

        Jinliang Liu,Yanmin Jia,Jun Wang 한국섬유공학회 2019 Fibers and polymers Vol.20 No.9

        The aim of the study is to validate the effect of glass fiber and polypropylene fiber on improving the mechanicaland durability properties of concrete. In this regard, glass fiber, polypropylene fiber and hybrid fiber were added to concrete,respectively. This paper conducted the compressive and bending flexural tests to confirm that the fiber enhances themechanical properties of concrete. In order to evaluate the durability of fiber reinforced concrete, the rapid chloride migrationtest and rapid chloride penetration test were carried out. The comparisons of experimental results illustrate that the hybridfiber reinforced concrete has the most significant effect on the concrete properties improvements. Moreover, comparing withthe glass fiber reinforced concrete, the polypropylene fiber reinforced concrete plays a better performance on mechanical anddurability properties.

      • Tea seed saponin(TSS) improve lipid metabolism and oxidative stress in high fat diet(HFD)-induced obese mice

        Shuang Liu,Huishan Qin,Yanmin Su,Jiali Li,Wenjing Cao,Wen He,Zhen Zeng,Qi Qi Pang,Jia-Le Song 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        To investigate the effect of TSS on lipid metabolism and oxidative stress in HFD mice. The body weight and food intake were observed. The serum SOD, MDA, GSH, TC, TG, HDL-C, LDL-C were determined by kits. Western Blotting was used to detect the levels of PPAR-γ, AMPK, SIRT1 and PGC-1α. TSS treatment reduced the body weight, Lee"s index and fat organ indices of mice in the HFD group. Compared with the control(CON) group, the serum TC, TG and LDL-C in the HFD group were increased, Administrated with TSS can improve abnormal blood lipid levels. Compared with the CON group, the serum SOD level in HFD group was significantly reduced(P<0.05), and MDA level was increased; while the levels of serum MDA in the TSS group decreased and SOD level increased. The pathological sections showed that TSS could improve the degree of hepatic steatosis. TSS also increased the levels of PPAR-γ, AMPK, SIRT1 and PGC-1α, and the effect of the high-dose group was the most significant. TSS can reduce body weight and fat accumulation, improve lipid metabolism disorder and oxidative stress caused by HFD.

      • KCI등재

        Multi-objective particle swarm optimization with dynamic population size

        Shu Xiaoli,Liu Yanmin,Liu Jun,Yang Meilan,Zhang Qian 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.1

        There are many complex multi-objective optimization problems in the real world, which are difficult to solve using traditional optimization methods. Multi-objective particle swarm optimization is one of the effective algorithms to solve such problems. This paper proposes a multi-objective particle swarm optimization with dynamic population size (D-MOPSO), which helps to compensate for the lack of convergence and diversity brought by particle swarm optimization, and makes full use of the existing resources in the search process. In D-MOPSO, population size increases or decreases depending on the resources in the archive, thereby regulating population size. On the one hand, particles are added according to local perturbations to improve particle exploration. On the other hand, the non-dominated sorting and population density are used to control the population size to prevent the excessive growth of population size. Finally, the algorithm is compared with 13 competing multi-objective optimization algorithms on four series of benchmark problems. The results show that the proposed algorithm has advantages in solving different benchmark problems.

      • SCIESCOPUSKCI등재

        Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling

        Zhan, Yingzhuan,Chen, Yinnan,Liu, Rui,Zhang, Han,Zhang, Yanmin 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8

        It has been suggested that combined effect of natural products may improve the treatment effectiveness in combating proliferation of cancer cells. Here, we examined the combined anticancer activities of compounds of three natural origin including baicalein, curcumin, and resveratrol with chemotherapy drug paclitaxel respectively, which showed that combination of paclitaxel with curcumin exhibited synergistic growth inhibition and induced significant apoptosis in MCF-7 cell lines. Treatment of MCF-7 cell lines with paclitaxel and curcumin induced the apoptosis of regulatory protein Bcl-2 but decreased Bax expression. In addition, simultaneous treatment with paclitaxel and curcumin strongly inhibited paclitaxel-induced activities of EGFR signaling. Furthermore, the combination of paclitaxel and curcumin exerted increased anti-tumor efficacy on mouse models. Overall, our data described the promising therapeutic potential and underlying mechanisms of combining paclitaxel with curcumin in treating breast cancer.

      • KCI등재

        Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling

        Yingzhuan Zhan,Yinnan Chen • Rui Liu,Han Zhang,Yanmin Zhang 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8

        It has been suggested that combined effect ofnatural products may improve the treatment effectiveness incombating proliferation of cancer cells. Here, we examinedthe combined anticancer activities of compounds of threenatural origin including baicalein, curcumin, and resveratrolwith chemotherapy drug paclitaxel respectively, whichshowed that combination of paclitaxel with curcuminexhibited synergistic growth inhibition and induced significantapoptosis in MCF-7 cell lines. Treatment of MCF-7cell lines with paclitaxel and curcumin induced the apoptosisof regulatory protein Bcl-2 but decreased Baxexpression. In addition, simultaneous treatment with paclitaxeland curcumin strongly inhibited paclitaxel-inducedactivities of EGFR signaling. Furthermore, the combinationof paclitaxel and curcumin exerted increased anti-tumorefficacy on mouse models. Overall, our data described thepromising therapeutic potential and underlying mechanismsof combining paclitaxel with curcumin in treating breast cancer.

      • KCI등재

        Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method

        Mudalal Mahmoud,Wang Zhanqi,Mustafa Shockry,Liu Yiping,Wang Yao,Yu Jize,Wang Shengnan,Sun Xiaolin,Zhou Yanmin 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.5

        Background: An in vitro study on rapid culturing method of human gingival fibroblast cells (HGFCs) was established to investigate the potential use of the leukocyte-platelet rich fibrin (L-PRF) in tissue engineering technology, different medical fields, including periodontology and implantology. Methods: Eight biopsies were obtained from eight different donors and a modified culturing technique was developed to obtain HGFCs. The modified 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT assay was used to compare the cell viability when the modified culturing method was used in comparison to the standard method. Blood samples were collected from the same patients and L-PRF was isolated using a standard protocol. The releases of platelet-derived growth factor-AA and transforming growth factor-beta1 at various time intervals were observed using enzyme-linked immunosorbent assay (ELISA) kit. The proliferative effect of L-PRF on HGFCs was assessed by the cell counting kit—8 assay. Results: A simple and rapid modified method for in vitro HGFC culture yielded a cellular monolayer within three to nine days after cell culture. L-PRF with three-dimensional polymer fibers released growth factors that peaked during the first three hours and continued to produce up to 10 days. The L-PRF presented a dose-dependent effect on HGFCs proliferation where HGFCs proliferation increased with an increase in L-PRF concentration. Conclusion: The modified technique for the culture of HGFCs might be useful for the development of future experimental and clinical studies, besides L-PRF has great therapeutic potential in oral surgery fields. Background: An in vitro study on rapid culturing method of human gingival fibroblast cells (HGFCs) was established to investigate the potential use of the leukocyte-platelet rich fibrin (L-PRF) in tissue engineering technology, different medical fields, including periodontology and implantology. Methods: Eight biopsies were obtained from eight different donors and a modified culturing technique was developed to obtain HGFCs. The modified 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT assay was used to compare the cell viability when the modified culturing method was used in comparison to the standard method. Blood samples were collected from the same patients and L-PRF was isolated using a standard protocol. The releases of platelet-derived growth factor-AA and transforming growth factor-beta1 at various time intervals were observed using enzyme-linked immunosorbent assay (ELISA) kit. The proliferative effect of L-PRF on HGFCs was assessed by the cell counting kit—8 assay. Results: A simple and rapid modified method for in vitro HGFC culture yielded a cellular monolayer within three to nine days after cell culture. L-PRF with three-dimensional polymer fibers released growth factors that peaked during the first three hours and continued to produce up to 10 days. The L-PRF presented a dose-dependent effect on HGFCs proliferation where HGFCs proliferation increased with an increase in L-PRF concentration. Conclusion: The modified technique for the culture of HGFCs might be useful for the development of future experimental and clinical studies, besides L-PRF has great therapeutic potential in oral surgery fields.

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