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      • KCI등재

        A Study on the Formal Systematization within the 3D Modeling Designs - Focused on The Law of Grouping -

        Gu, Ling-Feng,Jeon, Hyung-Jin,Pak, Hong-Sik Korea Multimedia Society 2017 The journal of multimedia information system Vol.4 No.3

        As to talk about computer aided 3D modeling, it can be conformed to the popular aesthetics based theory of heightening the organizing useful visual information. This thesis heightens the formativeness of the 3D modeling from the angle of the Gestalt psychology and attempts a finding of a method as also explains among the grouping laws of Gestalt. They are the definitions and the special features of 'The Law of Proximity', 'The Law of Similarity', 'The Law of Closure', 'The Law of Continuity', etc. And, through a logical, theoretical analysis, the relationships between such laws are found out. And the case examples of the uses of such laws in the 3D animation character designs and the situation in which such laws are applied to the things in the actual lives are analyzed. If it is intended to improve the formativeness of the 3D model forms, the rules of the simplicity, the safety, and the symmetry must be pursued according to the visual recognitions of the human beings. Because the actual objects are seen and touched, other than the visual pursuits by the human beings, the functionalities and the practicalities of the objects must be considered.

      • KCI등재

        A Systematic Study of the Meaning Conveyed by Morphology in 3D Modeling Design

        Ling Feng Gu,박홍식 한국콘텐츠학회 2023 International Journal of Contents Vol.19 No.1

        Implementation of 3D modeling design through morphological systematization represents a cuttingedge design methodology. However, this innovative approach has yet to establish a cohesive theoretical framework. Therefore, this paper utilized principles of Gestalt psychology as a foundation for significant research. By analyzing characteristics of organizational principles, the following eight essential keywords related to morphological systematization were proposed: “similar color,” “similar size,” “similar shape,” “distance,” “response,” “directional,” “overlapping,” and “incomplete.” These keywords were then synthesized to construct a morphological system framework that could allow content developers to aesthetically investigate various forms of 3D modeling and assess the strength of their formative attributes.

      • KCI등재

        3D-Printed Prosthesis Replacement for Limb Salvage after Radical Resection of an Ameloblastoma in the Tibia with 1 Year of Follow Up: A Case Report

        Dehong Feng,Junshan He,Chenyu Zhang,Ling Wang,Xiaofeng Gu,Yu Guo 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.9

        Ameloblastoma in the tibia is rare. Limb reconstruction after tumor resection is challenging in terms of selection of the operativemethod. Here, we report a case of radical resection of an ameloblastoma in the mid-distal tibia combined with limb salvage usinga three-dimensional (3D)-printed prosthesis replacement, with 1-year follow-up results. After receiving local institutional reviewboard approval, a titanium alloy prosthesis was designed using a computer and manufactured with 3D-printing technology. Duringthe operation, the stem of the prosthesis was inserted closely into the proximal tibial medullary cavity. Then, the metal anklemortise and the talus were compacted closely. Radiographic results at 1-year follow up showed that the prosthesis was wellplaced, and no loosening was observed. The Musculoskeletal Tumor Society (MSTS) 93 functional score was 26 points, and thefunctional recovery percentage was 86.7%. Computer-assisted 3D-printing technology allowed for more volume and structuralcompatibility of the prosthesis, thereby ensuring a smooth operation and initial prosthetic stabilization. During the follow up, thepresence of bone ingrowths on the porous surface of some segments of the prosthesis suggested good outcomes for long-term biologicalintegration between the prosthesis and host bone.

      • KCI등재

        The antibacterial activity of E. coli bacteriophage lysin lysep3 is enhanced by fusing the Bacillus amyloliquefaciens bacteriophage endolysin binding domain D8 to the C-terminal region

        Shuang Wang,Jingmin Gu,Meng Lv,Zhimin Guo,Guangmou Yan,Ling Yu,Chongtao Du,Xin Feng,Wenyu Han,Changjiang Sun,Liancheng Lei 한국미생물학회 2017 The journal of microbiology Vol.55 No.5

        Bacteriophage endolysin is one of the most promising antibioticsubstitutes, but in Gram-negative bacteria, the outermembrane prevents the lysin from hydrolyzing peptidoglycansand blocks the development of lysin applications. Theprime strategy for new antibiotic substitutes is allowing lysinto access the peptidoglycan from outside of the bacteria byreformation of the lysin. In this study, the novel Escherichiacoli (E. coli) phage lyase lysep3, which lacks outside-in catalyticability, was fused with the N-terminal region of theBacillus amyloliquefaciens lysin including its cell wall bindingdomain D8 through the best manner of protein fusionbased on the predicted tertiary structure of lysep3-D8 to obtainan engineered lysin that can lyse bacteria from the outside. Our results showed that lysep3-D8 could lyse both Gramnegativeand Gram-positive bacteria, whereas lysep3 and D8have no impact on bacterial growth. The MIC of lysep3-D8on E. coli CVCC1418 is 60 μg/ml; lysep3-D8 can inhibit thegrowth of bacteria up to 12 h at this concentration. The bactericidalspectrum of lysep3-D8 is broad, as it can lyse of allof 14 E. coli strains, 3 P. aeruginosa strains, 1 Acinetobacterbaumannii strain, and 1 Streptococcus strain. Lysep3-D8 hassufficient bactericidal effects on the 14 E. coli strains testedat the concentration of 100 μg/ml. The cell wall binding domainof the engineered lysin can destroy the integrity of theouter membrane of bacteria, thus allowing the catalytic domainto reach its target, peptidoglycan, to lyse the bacteria. Lysep3-D8 can be used as a preservative in fodder to benefitthe health of animals. The method we used here proved to bea successful exploration of the reformation of phage lysin.

      • KCI등재

        Multilocus Sequence Typing and Virulence Factors Analysis of Escherichia coli O157 Strains in China

        Xiao W. Ji,Ya L. Liao,Ye F. Zhu,Hai G. Wang,Ling Gu,Jiang Gu,Chen Dong,Hong L. Ding,Xu H. Mao,Feng C. Zhu,Quan M. Zou 한국미생물학회 2010 The journal of microbiology Vol.48 No.6

        Escherichia coli O157:H7, an important food-borne pathogen, has become a major public health concern worldwide. The aim of this study was to investigate the molecular epidemiologic feature of E. coli O157:H7strains in China. 105 E. coli O157:H7 isolates were collected from various hosts and places over 9 years. A multilocus sequence typing scheme (MLST) was applied for bacteria genotyping and polymerase chain reaction (PCR) was used for virulence factor identification. Seven new MLST sequence types (STs), namely ST836, ST837, ST838, ST839, ST840, ST841, and ST842 were identified, which grouped into two lineages. Phylogenetic analysis suggested that the most two frequent STs in China, ST837 and ST836, may be the derivatives of E. coli O157:H7 Sakai or E. coli O157:H7 EDL933. Geographical diversity and host variety of E. coli O157:H7 were observed in China. In addition, the different distribution of tccp was detected. The data presented herein provide new insights into the molecular epidemiologic feature of E. coli O157:H7, and aid in the investigation of the transmission regularity and evolutionary mechanism of E. coli O157:H7.

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