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      • KCI등재후보

        예술디자인학과 학생의 그릿과 진로준비행동 관계에서 회복탄력성의 매개효과

        Lili Zhang,Yu Wang,고영춘 국제인문사회연구학회 2024 Studies on Humanities and Social Sciences (SHSC) Vol.6 No.1

        Mediating Effect of Resilience in the Relationship Between Grit and Career Preparation Behavior of Art Design Students Lili Zhang,** Yu Wang,*** & Youngchun Ko**** Abstract: This study is to explore the mediating effect of resilience in the influence of grit on career preparation behavior for students in the department of art design. The subjects of the study are 524 students in the department of art design at H and D universities in Heilongjiang Province, China, and reliability, correlation, and regression analysis are conducted using the SPSS 25 program. The relationship among grit, resilience, and career preparation behavior is explored for university students in the department of art design. It is confirmed that resilience partially mediated grit's influence on career preparation behavior. Therefore, in order to promote career preparation behavior of students in the department of art design, university members should create a psychological and material environment for university students so that they can improve their grits and cultivate resilience. Key Words: Grit, Resilience, Career Preparation Behavior, Mediating Effect, Department of Art Design □ 접수일: 2024년 1월 31일, 수정일: 2024년 2월 10일, 게재확정일: 2024년 2월 20일* 이 논문은 주저자인 장려려의 박사학위논문을 발췌하여 수정・보완을 한 것임. ** 주저자, 세한대학교 대학원 교육학과 박사과정(First Author, Doctoral Course, Sehan Univ., Email: hxcizhanglili@126.com)*** 공동저자, 세한대학교 대학원 교육학과 박사과정(Co-author, Doctoral Course, Sehan Univ., Email: 342049496@qq.com)**** 교신저자, 세한대학교 교직과/ 대학원 교육학과 교수(Corresponding Author, Professor, Sehan Univ., Email: ycko@sehan.ac.kr)

      • KCI등재후보

        예술디자인학과 학생의 그릿과 학교적응 관계에서자기효능감의 매개효과

        Yu Wang,Lili Zhang,고영춘 국제인문사회연구학회 2024 Studies on Humanities and Social Sciences (SHSC) Vol.6 No.1

        Mediating Effect of Resilience in the Relationship Between Grit and Career Preparation Behavior of Art Design Students Yu Wang,** Lili Zhang,*** & Youngchun Ko**** Abstract: This study aims to find ways to improve adaptation to school for students in the department of art design. The subjects of the study are 319 students in the department of art design in Hainan Province of China, and reliability, correlation, and regression analysis are conducted using the SPSS 25 program. The relationship among grit, self-efficacy, and adaptation to school is explored for university students in the department of art design. It is confirmed that self-efficacy partially mediated grit's influence on adaptation to school. Therefore, in order to enhance the adaptation of art design students to school, university members should develop each educational program and teaching method strategy etc for them so that grit can be improved and self-efficacy can be cultivated. Key Words: Grit, Serlf-efficacy, Adaptation to School, Mediating Effect, Department of Art Design □ 접수일: 2024년 1월 31일, 수정일: 2024년 2월 17일, 게재확정일: 2024년 2월 28일* 이 논문은 주저자인 왕우의 박사학위논문을 발췌하여 수정・보완을 한 것임. ** 주저자, 세한대학교 대학원 교육학과 박사과정(First Author, Doctoral Course, Sehan Univ., Email: 342049496@qq.com)*** 공동저자, 세한대학교 대학원 교육학과 박사과정(Co-author, Doctoral Course, Sehan Univ., Email: hxcizhanglili@126.com)**** 교신저자, 세한대학교 교직과/ 대학원 교육학과 교수(Corresponding Author, Professor, Sehan Univ., Email: ycko@sehan.ac.kr)

      • KCI등재

        Radiation Force Calculation and Acoustic Power Measurement for a Cylindrical Concave Transducer Based on the Ray Acoustic Model

        Lili Yu,Wende Shou,Chun Hui,Bing Hu 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.4

        New relationships between the radiation force and the acoustic power for a cylindrical concave transducer were derived based on the ray acoustic model. The performance of this model is compared with that of the far-field integration model. The numerical results showed excellent agreement. Thus, these two models can be applied in the correction of measured results. Moreover, the formula based on the ray acoustic model can be applied more widely in practice because of its simplicity. The experimental results demonstrated further the reliability of the relationships between the radiation force and the acoustic power in theory, and the feasibility of using cylindrical concave transducers based on the ray acoustic model in practice.

      • KCI등재

        Transparent Lamellar Porous Material and Its Greatly Reduced Dielectric Constant

        Lili Liu,Cuijiao Zhao,Yawen Huang,Xiaonan Wei,Hongtao Yu,Junxiao Yang 한국고분자학회 2017 Macromolecular Research Vol.25 No.10

        One trend for low dielectric materials is to reach low dielectric constant values at as low porosity as possible. In this work, a lamellar porous material was prepared by spin-coating of poly(vinyl alcohol) (PVA)/manganese dioxide (MnO2) nanosheet composited film, followed by cross-linking of PVA and removing nanosheets. FTIR, XRD and TGA measurement results demonstrate that the templates were almost completely removed. SEM image shows that the etched PVA film has a lamellar porous structure. Dielectric test results indicate that at the porosity of only 17.5%, the dielectric constant of porous PVA is reduced to approximately half that of neat cross-linked PVA. The serial model shows a good consistence with experimental dielectric constant value. This explains well the high efficiency of lamellar porous structure in reducing dielectric constant.

      • SCIESCOPUSKCI등재

        Isovitexin Protects Mice from Methicillin- Resistant Staphylococcus aureus-Induced Pneumonia by Targeting Sortase A

        ( Lili Tian ),( Xinliang Wu ),( Hangqian Yu ),( Fengying Yang ),( Jian Sun ),( Tiezhong Zhou ),( Hong Jiang ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.10

        The rise of methicillin-resistant Staphylococcus aureus (MRSA) has resulted in significant morbidity and mortality, and clinical treatment of MRSA infections has become extremely difficult. Sortase A (SrtA), a virulence determinant that anchors numerous virulence-related proteins to the cell wall, is a prime druggable target against S. aureus infection due to its crucial role in the pathogenicity of S. aureus. Here, we demonstrate that isovitexin, an active ingredient derived from a variety of traditional Chinese medicines, can reversibly inhibit SrtA activity in vitro with a low dose (IC<sub>50</sub>=24.72 μg/ml). Fluorescence quenching and molecular simulations proved the interaction between isovitexin and SrtA. Subsequent point mutation experiments further confirmed that the critical amino acid positions for SrtA binding to isovitexin were Ala-92, Ile-182, and Trp-197. In addition, isovitexin treatment dramatically reduced S. aureus invasion of A549 cells. This study shows that treatment with isovitexin could alleviate pathological injury and prolong the life span of mice in an S. aureus pneumonia model. According to our research, isovitexin represents a promising lead molecule for the creation of anti-S. aureus medicines or adjuncts.

      • SCISCIESCOPUS

        Adiponectin Regulates Bone Marrow Mesenchymal Stem Cell Niche Through a Unique Signal Transduction Pathway: An Approach for Treating Bone Disease in Diabetes : Adiponectin Regulates BMSC Niche

        Yu, Liming,Tu, Qisheng,Han, Qianqian,Zhang, Lan,Sui, Lei,Zheng, Leilei,Meng, Shu,Tang, Yin,Xuan, Dongying,Zhang, Jin,Murray, Dana,Shen, Qingping,Cheng, Jessica,Kim, Sung-Hoon,Dong, Lily Q.,Valverde, P Wiley (John WileySons) 2015 Stem Cells Vol.33 No.1

        <P>Adiponectin (APN) is an adipocyte-secreted adipokine that exerts well-characterized antidiabetic properties. Patients with type 2 diabetes (T2D) are characterized by reduced APN levels in circulation and impaired stem cell and progenitor cell mobilization from the bone marrow for tissue repair and remodeling. In this study, we found that APN regulates the mobilization and recruitment of bone marrow-derived mesenchymal stem cells (BMSCs) to participate in tissue repair and regeneration. APN facilitated BMSCs migrating from the bone marrow into the circulation to regenerate bone by regulating stromal cell-derived factor (SDF)-1 in a mouse bone defect model. More importantly, we found that systemic APN infusion ameliorated diabetic mobilopathy of BMSCs, lowered glucose concentration, and promoted bone regeneration in diet-induced obesity mice. In vitro studies allowed us to identify Smad1/5/8 as a novel signaling mediator of APN receptor (AdipoR)-1 in BMSCs and osteoblasts. APN stimulation of MC3T3-E1 osteoblastic cells led to Smad1/5/8 phosphorylation and nuclear localization and increased SDF1 mRNA expression. Although APN-mediated phosphorylation of Smad1/5/8 occurred independently from adaptor protein, phosphotyrosine interaction, pleckstrin homology domain, and leucine zipper containing 1, it correlated with the disassembly of protein kinase casein kinase 2 and AdipoR1 in immunoprecipitation experiments. Taken together, this study identified APN as a regulator of BMSCs migration in response to bone injury. Therefore, our findings suggest APN signaling could be a potential therapeutic target to improve bone regeneration and homeostasis, especially in obese and T2D patients.</P>

      • KCI등재

        Enhanced photocatalytic activity of TiO2/graphene by tailoring oxidation degrees of graphene oxide for gaseous mercury removal

        Yu Guan,Tao Hu,Jiang Wu,Lili Zhao,Fengguo Tian,Wei-Guo Pan,Ping He,Xuemei Qi,Fangqin Li,Kai Xu 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.1

        We used a simple method of graphene oxide (GO) preparation with different oxidation levels, and control the properties of the TiO2 nanocrystals by tuning the content and oxidation degree of GO to enhance the photocatalytic performance. During the hydrothermal reaction, reduction of GO, formation of TiO2 and chemical bonds between TiO2 and reduced graphene oxide (RGO) was achieved simultaneously. Characterization results showed that TiO2 properties such as crystalline grain and particle size could be tailored by the amount of functional groups, and that crystallinity was also controlled by GO degrees of oxidation. TiO2/RGO photocatalysts showed great efficiency of mercury oxidation, which reached 83.7% and 43.6% under UV and LED light irradiation, respectively. The effects of crystalline grain size and surface chemical properties on Hg0 removal under LED and UV light irradiation were analyzed. In addition, the properties of the photocatalysts before and after UV illumination were investigated, finding that part of Ti-OH on TiO2 surface transformed to Ti-O-Ti. In a nutshell, this work could provide a new insight into enhancing activity of photocatalysts and understanding the photocatalytic mechanism.

      • Novel integrative soft computing for daily pan evaporation modeling

        LiLi Liu,Yongjun Zhu,Yu Zhang,Peng Wang,Loke Kok Foong 국제구조공학회 2022 Smart Structures and Systems, An International Jou Vol.30 No.4

        Regarding the high significance of correct pan evaporation modeling, this study introduces two novel neurometaheuristic approaches to improve the accuracy of prediction for this parameter. Vortex search algorithms (VSA), sunflower optimization (SFO), and stochastic fractal search (SFS) are integrated with a multilayer perceptron neural network to create the VSA-MLPNN, SFO-MLPNN, and SFS-MLPNN hybrids. The climate data of Arcata-Eureka station (operated by the US environmental protection agency) belonging to the years 1986-1989 and the year 1990 are used for training and testing the models, respectively. Trying different configurations revealed that the best performance of the VSA, SFO, and SFS is obtained for the population size of 400, 300, and 100, respectively. The results were compared with a conventionally trained MLPNN to examine the effect of the metaheuristic algorithms. Overall, all four models presented a very reliable simulation. However, the SFS-MLPNN (mean absolute error, MAE = 0.0997 and Pearson correlation coefficient, R<sub>P</sub> = 0.9957) was the most accurate model, followed by the VSA-MLPNN (MAE = 0.1058 and R<sub>P</sub> = 0.9945), conventional MLPNN (MAE = 0.1062 and R<sub>P</sub> = 0.9944), and SFO-MLPNN (MAE = 0.1305 and RP = 0.9914). The findings indicated that employing the VSA and SFS results in improving the accuracy of the neural network in the prediction of pan evaporation. Hence, the suggested models are recommended for future practical applications.

      • KCI등재

        On asymmetric generalization of the Weibull distribution by scale–location mixing of normal laws

        V.Yu. Korolev,Lily Kurmangazieva,A.I. Zeifman 한국통계학회 2016 Journal of the Korean Statistical Society Vol.45 No.2

        Two approaches are suggested to the definition of asymmetric generalized Weibull distribution. These approaches are based on the representation of the two-sided Weibull distributions as variance–mean normal mixtures or more general scale–location mixtures of the normal laws. Since both of these mixtures can be limit laws in limit theorems for random sums of independent random variables, these approaches can provide additional arguments in favor of asymmetric two-sided Weibull-type models of statistical regularities observed in some problems related to stopped random walks, in particular, in problems of modeling the evolution of financial markets

      • KCI등재

        A Novel Anti-Microbial Peptide from Pseudomonas, REDLK Induced Growth Inhibition of Leishmania tarentolae Promastigote In Vitro

        Yanhui Yu,Panpan Zhao,Lili Cao,Pengtao Gong,Shuxian Yuan,Xinhua Yao,Yanbing Guo,Hang Dong,Weina Jiang 대한기생충학ㆍ열대의학회 2020 The Korean Journal of Parasitology Vol.58 No.2

        Leishmaniasis is a prevalent cause of death and animal morbidity in underdeveloped countries of endemic area. However, there is few vaccine and effective drugs. Antimicrobial peptides are involved in the innate immune response in many organisms and are being developed as novel drugs against parasitic infections. In the present study, we synthesized a 5-amino acid peptide REDLK, which mutated the C-terminus of Pseudomonas exotoxin, to identify its effect on the Leishmania tarentolae. Promastigotes were incubated with different concentration of REDLK peptide, and the viability of parasite was assessed using MTT and Trypan blue dye. Morphologic damage of Leishmania was analyzed by light and electron microscopy. Cellular apoptosis was observed using the annexin V-FITC/PI apoptosis detection kit, mitochondrial membrane potential assay kit and flow cytometry. Our results showed that Leishmania tarentolae was susceptible to REDLK in a dose-dependent manner, disrupt the surface membrane integrity and caused parasite apoptosis. In our study, we demonstrated the leishmanicidal activity of an antimicrobial peptide REDLK from Pseudomonas aeruginosa against Leishmania tarentolae in vitro and present a foundation for further research of anti-leishmanial drugs.

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