정상 한국인에서 연령증가에 따른 혈장 Dehydroepiandrosteronesulfate ( DHEA-S ) 농도 및 DHEA - S / cortisol 비의 변화

박성우,유형준,임성희,최문기,유재명,박민숙,이권엽,박철수,김철홍,김현규,김두만,박규용 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.2

Backgroud: DHEA-S is the most abundant steroid hormone in circulation, and primarily secreted from the adrenal cortex, but its physiological role is little known. One of the characteristic features of DHEA-S is progressive decrement of plasma DHEA-S level with advancing age, in contrast, plasma levels of other adrenal hormones are not chaging or littie decreasing. To grasp the trends of plasma DHEA-S level and DHEA-S/cortisol ratio by age in healthy Korean, we measured the plasma DHEA-S levels and DHEA-S/cortisol ratios in healthy Korean. Methods: Healthy Korean(men: 99, women: 102, age range: 15-97 year old)were studied. Subjects were not taking drugs(such as glucocorticoid or androgenic medication) or cigarettes known to modify the plasma level of DHEA-S and cortisol, and had no evidence of hepatic, renal disease or hyperlipidemia as determined by serum lipid, bilirubin, SGOT, SGPT, BUN, creatinine. Data were analyzed by 10-year age group for men and women: i.e, 10-19, 20-29, 30-39, 40- 49, 50-59, 60-69, 70-79, 80-89 and 90 year or more. Plasma DHEA-S levels were measured by using a commercially available RIA kit with 125I labeled-DHEA-SO4(Coat-A Count DHEA-SO4), and for the measurement of plasma cortisol levels, commercial Gamma Coat TM[125I] Cortisol Radioimmunassay Kit was used. Results:. 1) In both men and women, plasma DHEA-S level showed high interindividual variation within the same age group. 2) There were individual sex differences in plasma levels of DHEA-S, in all age groups, plasma DHEA-S levels were significantly higher values for men than for women. 3) Maximum plasma DHEA-S levels(men; 237+-3.35 ug/dL, women; 108+-17.5 ug/dL) were at third decade in both men and women. 4) Both men and women showed the continuous decline in plasma DHEA-S level with age. These age-related decline was more prominent in men than in women(men; y= -3.152 * +292.6, r2= 0.8459, P$lt;0.05, women; y= -1.417 * +143.3, r2 = 0.7278, P$lt; 0.05). 5) As an index of aging, there was no stastical difference between DHEA-S and DHEA- S/cortisol ratio. Conclusion: In healthy Korean, there were high interindividual variation of plasrna DHEA-S levels. In both men and women plasma DHEA-S level was peak at third decade, and from when it declined progressively with age. These results suggest that although the reliability of single plasma DHEA-S measurement are limited, the decline of DHEA-S with advancing age might be a specific marker of endocrinologic hormonal milieu(aging index). Also, concerning to individual adrenal secreting capacity, we measured DHEA-S/cortisol ratio. But we did not found that plasma DHEA-S/cortisol ratio is superior to the plasma DHEA-S level as an aging index. (J Kor Soc Endocrinol 12:245-254, 1997)

중환자에서 동맥혈 가스분석 횟수와 그로인한 실혈량에 대한 연구

이석열,전철우,정영수,오희숙,마분란,이정미,정혜영,이만복,이길노 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Arterial blood gas analysis is the most comon exam in intensive care unit. In this study, the frequency of blood gas analysis and the amount of blood loss after Blood Gas Analysis in Intensive Care Unit were observed. Methods : From November 1999 to February 2000, 115 patients admitted to intensive care unit at Soonchunhyang university Kumi hospital were studied prospectively for the frequency of blood gas analysis and the amount of blood loss after blood gas analysis in Intensive Care Unit. Results : The mean value of frequency of blood gas analysis was 6.41±6.49 and the mean value of amount of blood loss after blood gas analysis was 0.78ml. This was lower than that of other foreign reports. The patients with ventilator therapy above 24 hours showed higher frequency of blood gas analysis than that of not applied ventilator patients. Pulse oxymetry was applied to all patients and the frequency of blood gas analysis was decreased due to the use of strict pulse oxymetry. Conclusion : Doctors and nurses in intensive care unit keep in mind that adequate blood sampling is needed for the decrease of blood loss. Education and protocol for the decrease of blood loss after arterial blood gas analysis may be necessary.

Incisional Hernia in Adult Liver Transplant Recipients

( Ji Soo Lee ),( Kyeong Sik Kim ),( Chan Woo Cho ),( Kyo Won Lee ),( Gyu-seoung Choi ),( Jong Man Kim ),( Choon Hyuck David Kwon ),( Jae-won Joh ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Incisional hernia is one of the complication following abdominal operation. Patients undergoing liver transplantation have a high risk of developing an incisional hernia because of immunosuppression. The purpose of this study is to review incisional hernia cases after liver transplantation and to identify the risk factors for hernia formation. Methods: We retrospectively reviewed and analyzed the medical records of the ninety-four incisional hernia patients after liver transplant recipients from January 2000 to December 2015 in single center institution. Results: 1463 underwent adult liver transplantation during the study period. 94 Incisional hernia patients were found among them. The overall incisional hernia rate was 6.4 %. Mean age was 54 years old and 76.6 % were men. No significant difference was observed for sex, diagnosis, smoking, alcohol, albumin, Child-Pugh score, MELD score, intensive care unit stay, hepatorenal syndrome, ventilator, spontaneous bacterial peritonitis, diabetes, bile leakage, wound problems between patients with incisional hernia and patients without incisional hernia. The characteristics of patients with incisional hernia showed old recipient, more body weight, higher body mass index, living donor recipient compared with patients without incisional hernia. Hypertension, tuberculosis, rejection, postoperative complication event before hernia were significant risk factor (p<0.05). Conclusions: Present study identifies the risk factors for incisional hernia. Surgeons should strive to reduce the risk of incisional hernia after adult liver transplantation.

사서교사의 리더십에 관한 고찰

이만수 ( Man Soo Lee ) 한국디지틀도서관포럼 2014 디지틀 도서관 Vol.74 No.-

이 연구는 사서교사와 리더십에 대한 이론과, 사서교사가 갖추어야 할 리더십에 관하여 조사하여 고찰하는데 목적이 있다. 리더는 앞장을 서서, 여러 사람을 이끌어가는 사람이다. 리더십은 여러 사람을 이끌어 가는 사람이 가지고 있는 능력, 지도력이다. 사서교사는 학교도서관 담당 교사로서 학교도서관 운영을 잘 하는 능력 있는 리더이다. 사서교사는 (1) 솔선수범하여야 한다. (2) 자신감을 가져야 한다. (3) 부지런해야 한다. (4) 직원을 사랑해야 한다. (5) 책임감을 가져야 한다. The purpose of this study is to review the theories about teacher librarian and leadership. Leader is the person who lead the follow men. Leadership is the ability which the person has in leading the followmen. Teacher libralian is the leader who has the competency in operation of the school library. Thus the teacher librarian ought to 1) be the initiative and set an example; 2) have the self confidency; 3) be diligent; 4) love the followmen of school library; 5) possess the responsibility.

건진센터 수검자 자료를 이용한 비만지표에 대한 연구

김상만,최희정,이득주,김광민,윤수진 대한비만학회 1997 The Korean journal of obesity Vol.6 No.2

We have examined l5145 persons(7468 men 7677 women) to determine the role of Obesity Index(body mass index, WHR, body fat percent) on the risk of various chronic disease. All the subjects were pooled from Health Examination Center who took the annual health examination from June, 1994 through Jan, 1997, BMI(Body mass index, kg/㎡), WHR(Waist hip ratio) were measured and correlated with the frequency of chronic disease. In order to evaluated the BMI, WHR, Body Fat as an independent factors on rnorbidity, analysis of covariance was applied adjusted for age. The risk of variows chronic diseases were also analyzed with obesity, defined by BMI above 26kg/㎡ (men), 25kg/㎡ (women), by logistic regression adjusted age and sex. Risk of hypertension was 2.6 with 95% eonfidence interval of 1.9-2.8 in obese group. Risk of diabetes mel1itus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.2(2.3-4.4), 1.2(0.9-1.4), 2.1(1.7-2.8), 1.4(1.1-2.6) and 1.3(0.8-2.3) respectiveiy. The risk of various chronic diseases were also analyzed with obesity, WHR above 0.9(men), 0.81(women), by logistic regression adjusted age and sex. Risk of hypertension was 1.7 with 95% confidence interval of 1.4 -2.1 in obese group. Risk of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.1(2.3-4.0), 1.2(0.9-l.4), 1.4(1.1-2.6), 2.4(l.8-4.8) and 2.1(1.2-4.1) respectively. The BMI, WHR were independent risk factors for various chronic diseases.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

공공도서관의 독서회 : 부산광역시립도서관을 중심으로

이만수 明知大學校 文獻情報學會 2004 文獻情報學論集 Vol.8 No.-

이 연구는 부산광역시 교육청 산하 11개 시립도서관이 운영하고 있는 독서회의 목적, 활동 내용, 인원, 활동시기, 대상, 회지 등을 분석하여 독서회의 운영 사항을 파악한 것이다. This study is to represent importance of reading & reading club. and is to grasp reading clubs management through an analysis of name, purpose, subject of activities, the number, proper time of activities, target, bulletin for reading clubs of eleven city libraries in Pusan Metropolitan City

부여 백제시대 가마터의 고고지구자기 연구

이윤수,서광수,서만철 공주대학교 문화재보존과학연구소 2004 문화재과학기술 Vol.3 No.1

충남 부여군 가마터에 대한 고고지자기 연구를 실시하였다. 13개의 가마 시료로부터 구한 특성잔류자화는 열화학작용에 의해서 생성된 자철석에 의해서 수행되며, 가마가 575℃이상 가열된 후 식으면서 그 당시의 지구자기장에 의해서 획득된 것으로 밝혀졌다. 이번 연구에서 구한 특성잔류자화의 그 평균편각과 평균복각은 각각 3.9˚E와 39.4˚ (a_(95)=3.2˚)로서, 한반도의 시험적 영년변화곡선에 대비하여 구한 특성잔류자화의 획득 시기는 서기 1,583년(+44년, -36년)이다. The archaeomagnetic study is examined to determine archomagnetic age of the kiln located in Buyeo area, Chungnam province. The results document that the characteristic remanent magnetization(ChRM) for 13 samples is carried by magnetite grains formed by a thermochemical activity during cooling from more than 575˚C. The Site mean direction (declination and inclination) for the ChRM is 3.9˚E and 39.4˚ (a_(95)=3.2˚). We conclude that the ChRM acquired in A.D. 1,583 (+44 yr, -36 yr), correlating the t-KPSV (tentative Korea Paleoselcular Variation) curve.

하드 실시간 처리에서 보장 알고리즘에 관한 연구

李滿熙,李龍斗,蔡洙煥 한국항공대학교 1994 論文集 Vol.32 No.-

실시간 타스크가 어떤 분산처리시스템의 한 노드에서 발생했을 때, 만약 그 타스크가 주어진 시간 내에 수행이 보장되지 않는다면, 타스크의 전이가 이루어져야 한다. 그런데 불행히도 타스크 전이는 많은 통신시간을 요구한다. 본 논문에서는 하드 실시간 타스크의 특성을 더 잘 반영하는 요소들을 제안하고 이들을 이용하여 타스크의 보장률을 높힘으로서 가능한 한 타이스 전이를 줄이는 알고리즘을 제안했고 이 알고리즘을 시뮬레이션하였다. When a hard real-time task occurs at a node on a distributed system, if the task is not guaranteed to be executed within given deadline, it should be migrated to other nodes. Unfortunately, the task migration requires much communication overhead. We suggest some factors which can represent the characteristics of hard real-time tasks, propose a guarantee algorithm for reducing the number of task migration by increasing the local guarantee ratio, and simulatethe algorithm.

企嶪年金會計에 관한 考察

李萬秀 청주대학교 기업경영학연구소 1985 經營學論集 Vol.7 No.-