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費用中心의 機械셀-部品群의 經濟的 形成方法에 관한 硏究
李震圭,金英謙,金鎭勇 동국대학교 대학원 1991 大學院硏究論集-東國大學校 大學院 Vol.21 No.-
The purpose of this study is to develop a cost based heuristic algorithm selecting an optimal combination of machine cell and part family under the condition of minimizing total cost or number of exceptional elements. This heuristic algorithm considers cost elements such as processing cost, subcontract cost, and production frequency. This algorithm can be applied to real situation by using, preference, and production expert's importance or production ratio or flow ratio as a weight factor. When this proposed approach is applied to the real situation, expected benefits are as follows : the reduction of production lead time, work in process, labor force, tooling. rework and scrap, setup time. order time delivery, and paper work, additionally, it is expected that the human relationship and productivity can be improved.
장애유아 통합교육의 성공을 위한 예비 유아교사 교육과정 탐색
이진화,임원신 남서울대학교보건의료개발연구소 2004 보건복지 연구 논집 Vol.1 No.1
This study aims to develop the curriculum of early childhood teacher education for inclusion. It has been increasing an interest in an inclusive education for young children these days. However, there are several barries to perform it sucessfully. Among them, the most important thing to solve barries for an inclusion is to prepare and practice general early childhood teachers. It is discussed about the importance of beliefs, attitudes and roles of ECE teachers in an inclusion. Also, according to the roles of ECE teachers in an inclusion, the analysis of present curricula for ECE teacher education is examined and several important subjects including parent involvement, practicum, and a understanding of individual child development, are explored. Finally, it is discussed about the problems which make difficult to develop the curriculum of ECE teacher education for an inclusion and also presented some methods for a sucessful inclusion in ECE.
FUZZY 이론에 의한 트러스 構造物의 最適化에 관한 硏究
李奎遠,李珍遠,梁昌容 全北大學校 1996 論文集 Vol.42 No.-
Fuzzy theory is useful in dealing with vagueness and ambiguities concerned with subjective judgement of human beings. In this research the optimization of the section area of truss structure has been tested by using fuzzy theory. The section area of member was chosen with design variable and the weight function of strucure was chosen with objective function. According to changing constraint conditions linearly with using fuzzy set, various optimum object functions will be obtained by feasible direction method. This algorithm was applied practically to the 10 bar truss structure and subsequently came to almost same value of objective function. Therefore this algorithm appers to be effective method of section area optimization. Accordingly, the optimization of truss structures which utilizes the results of this study can be helpful in economical design of truss stuctures.
한국 재래식 된장 중 indole의 분포 및 indole 생성균
이은주,박선미,신진돈,김종규 嶺南大學校 環境問題硏究所 1991 環境硏究 Vol.11 No.1
Indole contents and microorganisms producing indole were investigated from traditional Korean soybean paste. Distributions of indole contents were 0∼140㎍/g in the soybean paste and the mean was 8.1㎍/g. Through quantitative analysis of indole and sensory evaluation indole was found to be the main cause of feacal odor in soybean paste. Microorganisms producing indole isolated in soybean paste were rods, Gram positive and spore formation, so they were Bacillus species. But the microorganisms were different from characters of known Bacillus species, so they were types of Bacillus species.
대구지역 공단과 인근 주거지역의 휘발성유기화합물질 오염도 평가
조완근,이진우 한국환경과학회 2004 한국환경과학회지 Vol.13 No.6
Air pollution from the Daegu industrial complex (DIC) in Korea has been a common nuisance and cause of complaints for nearby residents. The current study measured the indoor and outdoor levels of six VOC (benzene, toluene, ethylbenzene, and three isomeric xylenes) at two residential areas with a different proximity to the DDIC, plus the ambient levels at two industrial areas within the boundary of the DDIC. The QA/QC program included the range of correlation coefficient (0.94~0.99) for calibration curves, within the permissible range. Toluene was the most abundant VOC in the ambient air both in residential and industrial areas. Both indoor and outdoor air concentrations of all target VOC except benzene were higher in residential area near the DIC compared to that further away from the DIC. Moreover, the ambient air concentrations of all target VOC except benzene for two industrial sites (A and B) were significantly higher than the outdoor or indoor air concentrations in the two residential areas. The findings further suggested that VOC ambient levels measured in a residential area near the DIC be used as a potential indicator of odor-causing unidentified air pollutants transported from the DIC. Moreover, it was found that the elevated ambient toluene levels outweighed the indoor sources with respect to the environmental exposure of residents nearby the DIC. However, in the residential area further away from the DIC, the toluene indoor sources outweighed the outdoor sources.
인체혈장 중 에탐부톨의 HPLC 분석법의 검증 및 단일용량 투여에 의한 약물동태 연구
곽혜선,박경호,최준식,송진아,성민경,장정옥,이화정 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.2
An HPLC method was employed for the determination of ethambutol in human plasma. After addition of internal standard (IS, octylamine, 2 μg/mL) and alkalinization of the plasma with 5 M sodium hydroxide, the drug and IS were extracted into the mixture of chloroform and diethyl ether (40:60, v/v). Following a 15-min vortex-mixing and a 10-min centrifugation, the organic phase was spiked with 100 pL of phenylethylisocyanate (2000 μg/mL) for chemical derivatization, mixed for 5 min and evaporated to dryness under a stream of nitrogen. The residue was reconstituted with 100 μL of mobile phase and 20 pL was injected into Cl8 column with a mobile phase consisting of methanol:water (70:30, v/v). The samples were detected utilizing an ultraviolet detector at 200 nm. The method was specific and validated with a limit of 0.15 μg/mL. Infra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification. The applicability of this method was demonstrated by analysis of human plasma after oral administration of a single 1200-mg dose to 20 healthy subjects. From the plasma ethambutol concentration vs. time curves, the mean AUC was 9.61 ± 1.64 μg hr/mL. and Cmax of 2.68 μg/mL reached 2.73 hr after administration. The mean biological half-life of ethambutol was 3.46 ± 1.21 hr. Based on the results, this simple and validated assay could readily be used in any pharmacokinetic studies using humans.