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Huan Lan,Zhewen Dong,Yaqi Wu,Chaojie Chong,Zhiqiang Liu,Wanying Li,Zixian Wang,Junyang Liu,Qi Qi Pang,Jia-Le Song,Yanyuan Zhou 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
In this study, we investigated the antifibrotic effects of Rha on letrozole-induced PCOS in rats. Rha treatment restored letrozole-induced alterations in the body weight (BW), relative weights of the ovaries, and relative weights of uterine and visceral adipose tissues. Histological observation showed that Rha reduced the number of atretic follicles, cystic follicles, and fibrosis of the ovaries in the PCOS rats. Administration of Rha reduced letrozole-induced metabolic dysfunction by decreasing the serum levels of TG and TC and increasing the levels of HDL-C in the PCOS rats. Rha treatment also modulated the serum levels of sex hormones, which decreased the LH, E2 and T and increased the FSH in PCOS rats. Finally, Rha treatment appeared to increase the activity of PPAR-γ, reduce the activation of the TGF-β1/Smad pathway, and reduce the collagen I, α-SMA and CTGF levels in the ovaries of the PCOS rats. Our results demonstrated that Rha significantly ameliorated metabolic disturbances and ovarian fibrosis in the letrozole-induced PCOS rats. Rha may be an effective compound in preventing ovarian fibrosis in the future.
Huan Lan,Zhewen Dong,Yaqi Wu,Chaojie Chong,Zhiqiang Liu,Wanying Li,Zixian Wang,Junyang Liu,Qi Qi Pang,Jia-Le Song,Yanyuan Zhou 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
This study investigated the antifibrotic effects of SA on ovarian fibrosis in letrozole-induced PCOS in rats. SA treatment restored letrozole-induced alterations in the body weight (BW), relative weights of the ovaries, and visceral adipose tissues. Histological observation showed that SA reduced the number of atretic follicles, cystic follicles, and fibrosis of the ovaries in PCOS rats. SA treatment also modulated the serum levels of sex hormones, which decreased the luteinizing hormone (LH), and testosterone (T) and increased the follicle-stimulating hormone (FSH) in PCOS rats. Administration of SA reduced letrozole-induced metabolic dysfunction by decreasing the serum levels of triglyceride (TG) and total cholesterol (TC) and increasing the levels of high-density lipoprotein cholesterol (HDL-C) in PCOS rats. Finally, SA treatment appeared to increase the activity of PPAR-γ, reduce the activation of the TGF-β1/Smad pathway, and reduce the collagen I, α-SMA and CTGF levels in the ovaries of the PCOS rats. Our results demonstrated that SA significantly ameliorated ovarian fibrosis and abolic disturbances in the letrozole-induced PCOS rats.
Study on High Resistance Distance Relay in Directly Earth System
Liu, Huan-Zhang,Li, Ying-Hong The Korean Institute of Electrical Engineers 2011 The Journal of International Council on Electrical Vol.1 No.4
The coverage of transition resistance and the avoidance of load impedance is in essence a contradiction for distance protection. It's evident from the impedance plane that the requirement to avoid the load impedance results in that the action space of the distance relay is greatly limited, which accordingly reduces the ability of the relays to cover the transition resistance. In fact, there are some limitations to analyze the distance relays in the impedance plane. It would be better in the voltage plane. The three elements of distance relay in the voltage plane are the polarization voltage, operation voltage and operation characteristic, of which the polarization voltage is most important. The relay could ideally select pre-fault voltage as polarization voltage, while it practically employs the positive voltage. The difference between the two kinds of polarization voltage is negligible in the state of low impedance ground fault, while significant in the state of high impedance ground fault. Thus, this paper uses the memory and the non-fault phase parameters to gain the pre-fault voltage, that is, the new polarization voltage, and puts forward a new self-adaptive high impedance ground distance relay.
Characterization of the Parameters for the Refining Intensity in Terms of Performance
Huan Liu,Jixian Dong,Hui Jing,Xiya Guo,Lijie Qiao 한국펄프·종이공학회 2019 펄프.종이기술 Vol.51 No.2
Refining intensity is typically used to measure the efficiency of refining in the pulp and paper industry, and the refining intensity is difficult to analyze due to the various parameters influencing it. In this paper, the previously published refining intensities of a disc refiner were analyzed, and the characterization parameters were proposed. Based on the bar interactions, the refining intensity was established using theoretical derivation. The cut edge length (CEL), the CEL-based characterization parameters and bar interactions (BI) characterization parameters were used to show that the CEL directly reflected the number of bar interaction points, but it had no direct relationship with the bar interaction area (BIA) and bar interaction length (BIL). By analyzing the relationship between the different refining intensities and the properties of the fibers or pulp, it could be concluded that the specific refining energy (SRE) better reflected the variations in the beating degree of the pulp during the refining process compared with the specific surface load (SSL) and BI-based refining intensities. Also, the intensity based on the bar interaction length (BIL) can better characterize the changes in the average fiber length. However, all the intensities analyzed in this paper do not comprehensively describe the refining process and cannot predict all the parameters of the pulp and fibers but only partly characterize their properties. Therefore, further studies are required to establish a more comprehensive and precise measure of refining intensity.
Liu, Huan,Hao, Kuangrong,Ding, Yongsheng Korean Institute of Information Scientists and Eng 2017 Journal of Computing Science and Engineering Vol.11 No.3
In this paper, the abdominal-deformation measurement scheme is conducted on a shape-flexible mannequin using the DIC technique in a stereo-vision system. Firstly, during the integer-pixel displacement search, a novel fractal dimension based on an adaptive-ellipse subset area is developed to track an integer pixel between the reference and deformed images. Secondly, at the subpixel registration, a new mutual-learning adaptive particle swarm optimization (MLADPSO) algorithm is employed to locate the subpixel precisely. Dynamic adjustments of the particle flight velocities that are according to the deformation extent of each interest point are utilized for enhancing the accuracy of the subpixel registration. A test is performed on the abdominal-deformation measurement of the shape-flexible mannequin. The experiment results indicate that under the guarantee of its measurement accuracy without the cause of any loss, the time-consumption of the proposed scheme is significantly more efficient than that of the conventional method, particularly in the case of a large number of interest points.
Huan Liu,Kuangrong Hao,Yongsheng Ding 한국정보과학회 2017 Journal of Computing Science and Engineering Vol.11 No.3
In this paper, the abdominal-deformation measurement scheme is conducted on a shape-flexible mannequin using the DIC technique in a stereo-vision system. Firstly, during the integer-pixel displacement search, a novel fractal dimension based on an adaptive-ellipse subset area is developed to track an integer pixel between the reference and deformed images. Secondly, at the subpixel registration, a new mutual-learning adaptive particle swarm optimization (MLADPSO) algorithm is employed to locate the subpixel precisely. Dynamic adjustments of the particle flight velocities that are according to the deformation extent of each interest point are utilized for enhancing the accuracy of the subpixel registration. A test is performed on the abdominal-deformation measurement of the shape-flexible mannequin. The experiment results indicate that under the guarantee of its measurement accuracy without the cause of any loss, the time-consumption of the proposed scheme is significantly more efficient than that of the conventional method, particularly in the case of a large number of interest points.
Annual Financial Impact of Thyroidectomies for Nodular Thyroid Disease in China
Liu, Xiao-Yun,Zhu, Li-Jun,Cui, Dai,Wang, Zhi-Xiao,Chen, Huan-Huan,Duan, Yu,Shen, Mei-Ping,Zhang, Zhi-Hong,Wang, Xiao-Dong,Chen, Jia-Wei,Alexander, Erik Karl,Yang, Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14
A large proportion of patients with thyroid nodules in China undergo thyroidectomy in order to get confirmatory histology diagnosis. The financial impact of this modality remains to be investigated. To evaluate rationality of performing thyroidectomy without a routine FNA preoperatively from the economic perspective, we conducted a retrospective, observational study of all archival thyroidectomies with records of cost per stay (CPS), cost per day (CPD) and length of stay (LOS) from 2008 to 2013 in the First Affiliated Hospital of Nanjing Medical University. We compared all the parameters between cancer and non-cancer thyroidectomies. We recruited 6, 140 thyroidectomies with valid records of CPS, CPD and LOS in this period. The CPS of cancer thyroidectomy was significantly higher than non-cancer thyroidectomy. The percentage of cancer thyroidectomy increased from 26.5% to 41.6%. The percentage of annual cost of cancer thyroidectomies rose from 30.2% to 45.2%. The LOS for cancer and non-cancer thyroidectomy decreased while the CPD increased in the past six years. The estimated national cost in 2012 for all thyroidectomies would be USD 1.86 billion with USD 1.09 billion for non-cancer thyroidectomies. We have witnessed great improvement in the healthcare for patients with thyroid nodules in China. However, given limited healthcare resources, currently thyroid FNA for more precise preoperative diagnosis may help to curb the rapidly increasing demand in healthcare costs in the future for nodular thyroid disease in China.
Huan Liu,Jie Bai,Chunping Li,Shan Wang,Yarong Huang,QI WANG,WEIYAN SUN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.3
Ag nanoparticles (Ag NPs) embedded carbon nano¯bers (CNFs) were prepared by a new routewhich included chemical reaction process, electrospinning and calcination technique. The mor-phology and structure of the composite nano¯bers were investigated by scanning electron mi-croscopy, energy dispersive X-ray spectroscopy, transmission electron microscopy and X-raydi®raction. It indicated that Ag NPs were uniformly distributed in the CNFs. This e®ectivesynthesis method can be used to prepare other composite nano¯bers with functionality. The AgNPs/CNFs that served as supported catalysts were used in the styrene epoxidation by TBHP. The Ag NPs/CNFs catalyst showed its highly catalytic activity for the epoxidation of styrene(conversion: 40.6%, SO selectivity: 35.9%). This kind of composite nano¯ber membrane wasproved e®ectively catalytic activity and recycled easily in the styrene epoxidation.